ATE140458T1 - Imidazole derivate und diese enthaltende arzneimittel - Google Patents

Imidazole derivate und diese enthaltende arzneimittel

Info

Publication number: ATE140458T1
Authority: AT; Austria
Prior art keywords: products containing; imidazole derivatives; containing same; medicinal products; compounds
Prior art date: 1991-10-24

Application number

AT92921391T

Other languages

English (en)

Inventor

Keiko Koh

Mikio Taniguchi

Noriie Itoh

Hiroshi - Oaza-Tomado Kushida

Osamu Katoaka Haitsu B Morita

Hiroyoshi -Go C-To Yamada

Mastushiro

Kiyotaka Munesada

Kazuo - Tsuzuki

Mineo - Yatabe-Machi Kunihara

Yoshiji Fujita

Original Assignee

Upjohn Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-10-24

Filing date

1992-10-14

Publication date

1996-08-15

1992-10-14 Application filed by Upjohn Co filed Critical Upjohn Co

1996-08-15 Application granted granted Critical

1996-08-15 Publication of ATE140458T1 publication Critical patent/ATE140458T1/de

Links

RAXXELZNTBOGNW-UHFFFAOYSA-N 1H-imidazole Chemical class C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 title 1
229940079865 intestinal antiinfectives imidazole derivative Drugs 0.000 title 1
229940126601 medicinal product Drugs 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 abstract 1
206010007559 Cardiac failure congestive Diseases 0.000 abstract 1
206010019280 Heart failures Diseases 0.000 abstract 1
206010020772 Hypertension Diseases 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
150000002460 imidazoles Chemical class 0.000 abstract 1
238000010253 intravenous injection Methods 0.000 abstract 1
230000005923 long-lasting effect Effects 0.000 abstract 1
231100000053 low toxicity Toxicity 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Ophthalmology & Optometry (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicinal Preparation (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

AT92921391T 1991-10-24 1992-10-14 Imidazole derivate und diese enthaltende arzneimittel ATE140458T1 (de)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
JP27753791		1991-10-24
JP32347491		1991-12-07
JP9519192		1992-04-15
JP4216809A JPH06107661A (ja)	1991-10-24	1992-08-14	イミダゾール誘導体およびこれを有効成分とする医薬組成物

Publications (1)

Publication Number	Publication Date
ATE140458T1 true ATE140458T1 (de)	1996-08-15

Family

ID=27468309

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT92921391T ATE140458T1 (de)	1991-10-24	1992-10-14	Imidazole derivate und diese enthaltende arzneimittel

Country Status (11)

Country	Link
EP (2)	EP0609289B1 (de)
JP (2)	JPH06107661A (de)
AT (1)	ATE140458T1 (de)
AU (1)	AU661346B2 (de)
CA (1)	CA2118802A1 (de)
DE (1)	DE69212331T2 (de)
DK (1)	DK0609289T3 (de)
ES (1)	ES2091489T3 (de)
GR (1)	GR3021143T3 (de)
MX (1)	MX9206157A (de)
WO (1)	WO1993008193A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH06271576A (ja) *	1993-03-19	1994-09-27	Upjohn Co:The	イミダゾール誘導体の製法
US6005105A (en) *	1993-06-21	1999-12-21	Pharmacia & Upjohn Company	Process for producing imidazole derivative
JPH0710879A (ja) *	1993-06-21	1995-01-13	Upjohn Co:The	イミダゾール誘導体の製法
AUPN236595A0 (en)	1995-04-11	1995-05-11	Rescare Limited	Monitoring of apneic arousals
SE9903028D0 (sv) *	1999-08-27	1999-08-27	Astra Ab	New use
SK2692002A3 (en)	1999-08-30	2002-07-02	Aventis Pharma Gmbh	Use of inhibitors of the renin-angiotensin system in the prevention of cardiovascular events
US8969514B2 (en)	2007-06-04	2015-03-03	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
MX354786B (es)	2007-06-04	2018-03-21	Synergy Pharmaceuticals Inc	Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos.
CA2726917C (en)	2008-06-04	2018-06-26	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP2321341B1 (de)	2008-07-16	2017-02-22	Synergy Pharmaceuticals Inc.	Zur behandlung von erkrankungen des magen-darm-trakts, entzündlichen erkrankungen, krebs und anderen erkrankungen geeignete agonisten von guanylatcyclase
US9616097B2 (en)	2010-09-15	2017-04-11	Synergy Pharmaceuticals, Inc.	Formulations of guanylate cyclase C agonists and methods of use
JP2016514671A (ja)	2013-03-15	2016-05-23	シナジーファーマシューティカルズインコーポレイテッド	グアニル酸シクラーゼのアゴニストおよびその使用
WO2014151200A2 (en)	2013-03-15	2014-09-25	Synergy Pharmaceuticals Inc.	Compositions useful for the treatment of gastrointestinal disorders
CN105764916B (zh)	2013-06-05	2021-05-18	博士医疗爱尔兰有限公司	鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4250180A (en) *	1979-07-16	1981-02-10	Ortho Pharmaceutical Corporation	Method of treating arrhythmia
GB2128984B (en) *	1982-05-12	1985-05-22	Hoffmann La Roche	Diaza-bicyclic compounds
DE3347290A1 (de) *	1983-12-28	1985-07-11	Dr. Karl Thomae Gmbh, 7950 Biberach	Neue 2-phenyl-imidazole, ihre herstellung und diese verbindungen enthaltende arzneimittel
IE64514B1 (en) *	1989-05-23	1995-08-09	Zeneca Ltd	Azaindenes
IL96019A0 (en) *	1989-10-31	1991-07-18	Fujisawa Pharmaceutical Co	Imidazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same

1992
- 1992-08-14 JP JP4216809A patent/JPH06107661A/ja active Pending
- 1992-10-14 EP EP92921391A patent/EP0609289B1/de not_active Expired - Lifetime
- 1992-10-14 EP EP19920309342 patent/EP0540209A1/de active Pending
- 1992-10-14 ES ES92921391T patent/ES2091489T3/es not_active Expired - Lifetime
- 1992-10-14 DE DE69212331T patent/DE69212331T2/de not_active Expired - Fee Related
- 1992-10-14 JP JP5507722A patent/JPH07500336A/ja active Pending
- 1992-10-14 WO PCT/US1992/008584 patent/WO1993008193A1/en not_active Ceased
- 1992-10-14 AT AT92921391T patent/ATE140458T1/de not_active IP Right Cessation
- 1992-10-14 DK DK92921391.6T patent/DK0609289T3/da active
- 1992-10-14 CA CA002118802A patent/CA2118802A1/en not_active Abandoned
- 1992-10-14 AU AU27592/92A patent/AU661346B2/en not_active Ceased
- 1992-10-26 MX MX9206157A patent/MX9206157A/es unknown
1996
- 1996-09-25 GR GR960402509T patent/GR3021143T3/el unknown

Also Published As

Publication number	Publication date
JPH06107661A (ja)	1994-04-19
GR3021143T3 (en)	1996-12-31
JPH07500336A (ja)	1995-01-12
AU661346B2 (en)	1995-07-20
MX9206157A (es)	1994-05-31
CA2118802A1 (en)	1993-04-29
DE69212331D1 (de)	1996-08-22
EP0540209A1 (de)	1993-05-05
EP0609289B1 (de)	1996-07-17
DE69212331T2 (de)	1997-01-09
EP0609289A1 (de)	1994-08-10
WO1993008193A1 (en)	1993-04-29
ES2091489T3 (es)	1996-11-01
AU2759292A (en)	1993-05-21
DK0609289T3 (da)	1996-11-25

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Legal Events

Date	Code	Title	Description
1997-02-15	UEP	Publication of translation of european patent specification
1998-07-15	REN	Ceased due to non-payment of the annual fee