ATE140460T1 - Echinocandin-b-derivat - Google Patents

Echinocandin-b-derivat

Info

Publication number: ATE140460T1
Authority: AT; Austria
Prior art keywords: echinocandin; derivative; activity; chem; compound
Prior art date: 1991-10-17

Application number

AT92309348T

Other languages

English (en)

Inventor

Frances Aileen Bouffard

James F Dropinski

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-10-17

Filing date

1992-10-14

Publication date

1996-08-15

1992-10-14 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

1996-08-15 Application granted granted Critical

1996-08-15 Publication of ATE140460T1 publication Critical patent/ATE140460T1/de

Links

FAUOJMHVEYMQQG-HVYQDZECSA-N echinocandin B Chemical class C1([C@H](O)[C@@H](O)[C@H]2C(=O)N[C@H](C(=O)N3C[C@H](C)[C@H](O)[C@H]3C(=O)N[C@H](O)[C@H](O)C[C@@H](C(N[C@H](C(=O)N3C[C@H](O)C[C@H]3C(=O)N2)[C@@H](C)O)=O)NC(=O)CCCCCCC\C=C/C\C=C/CCCCC)[C@@H](C)O)=CC=C(O)C=C1 FAUOJMHVEYMQQG-HVYQDZECSA-N 0.000 title 1
239000002253 acid Substances 0.000 abstract 1
230000003115 biocidal effect Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000002101 lytic effect Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Communicable Diseases (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT92309348T 1991-10-17 1992-10-14 Echinocandin-b-derivat ATE140460T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US77577391A	1991-10-17	1991-10-17

Publications (1)

Publication Number	Publication Date
ATE140460T1 true ATE140460T1 (de)	1996-08-15

Family

ID=25105455

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT92309348T ATE140460T1 (de)	1991-10-17	1992-10-14	Echinocandin-b-derivat

Country Status (5)

Country	Link
EP (1)	EP0539088B1 (de)
JP (1)	JPH05239095A (de)
AT (1)	ATE140460T1 (de)
CA (1)	CA2080756A1 (de)
DE (1)	DE69212267T2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2271571A (en) *	1992-10-19	1994-04-20	Merck & Co Inc	Aminoalkyl ether of cyclohexapeptidylamine compounds
AU674233B2 (en) *	1993-05-04	1996-12-12	Merck & Co., Inc.	Cyclohexapeptidyl aminoalkyl ethers
DE69513408T2 (de) *	1994-08-23	2000-06-08	Merck & Co., Inc.	Ein verbessertes verfahren für die herstellung von seitenketten-derivaten von cyclohexapeptidyl-lipopeptiden
US5516757A (en) *	1994-09-16	1996-05-14	Merck & Co., Inc.	Semi-synthetic lipopeptides, compositions containing said lipopeptides, and methods of use
AU6564000A (en) *	1999-07-27	2001-02-13	Aventis Pharma Deutschland Gmbh	Novel cyclohexapeptide compounds, processes for their production and their use as a pharmaceutical
CN102464704B (zh) *	2010-11-05	2013-12-11	上海医药工业研究院	一种化合物及其制备方法和用途
CN117947021B (zh) *	2024-03-27	2025-05-09	北京瑞贝怡可生物科技有限公司	核酸提取裂解结合液、核酸提取试剂盒及提取方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK173802B1 (da) *	1988-09-12	2001-11-05	Merck & Co Inc	Præparat til behandling af Pneumocystis carinii infeksioner og anvendelse af et cyclohexapeptid til fremstilling af et lægemiddel mod Pneumocystis carinii infektioner
IL94862A (en) *	1989-06-30	1994-10-07	Merck & Co Inc	History of Echinocandin Antifungal Antibiotics, Its Production and Pharmaceutical Preparations Containing It
CA2037957A1 (en) *	1990-03-12	1991-09-13	Merck & Co., Inc.	N-acylated cyclohexapeptide compounds
US5310873A (en) *	1990-03-12	1994-05-10	Merck & Co., Inc.	Cyclohexapeptide compound
US5159059A (en) *	1990-05-29	1992-10-27	Merck & Co., Inc.	Process for reduction of certain cyclohexapeptide compounds

1992
- 1992-10-14 EP EP92309348A patent/EP0539088B1/de not_active Expired - Lifetime
- 1992-10-14 AT AT92309348T patent/ATE140460T1/de not_active IP Right Cessation
- 1992-10-14 DE DE69212267T patent/DE69212267T2/de not_active Expired - Fee Related
- 1992-10-15 JP JP4277137A patent/JPH05239095A/ja active Pending
- 1992-10-16 CA CA002080756A patent/CA2080756A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EP0539088B1 (de)	1996-07-17
DE69212267T2 (de)	1997-01-30
EP0539088A1 (de)	1993-04-28
DE69212267D1 (de)	1996-08-22
CA2080756A1 (en)	1993-04-18
JPH05239095A (ja)	1993-09-17

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Legal Events

Date	Code	Title	Description
1997-01-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties