ATE416189T1 - Cyclohexapeptide, deren herstellung und verwendung in pharmazeutische zusammensetzungen - Google Patents

Cyclohexapeptide, deren herstellung und verwendung in pharmazeutische zusammensetzungen

Info

Publication number: ATE416189T1
Authority: AT; Austria
Prior art keywords: sub; aryl; substituted; alkyl; independently
Prior art date: 1999-07-27

Application number

AT00953050T

Other languages

English (en)

Inventor

Lal Bansi

Genbhau Gund Vitthal

Kumar Gangopadhyay Ashok

Original Assignee

Aventis Pharma Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-07-27

Filing date

2000-07-15

Publication date

2008-12-15

2000-07-15 Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh

2008-12-15 Application granted granted Critical

2008-12-15 Publication of ATE416189T1 publication Critical patent/ATE416189T1/de

Links

239000008194 pharmaceutical composition Substances 0.000 title 1
125000003118 aryl group Chemical group 0.000 abstract 4
125000000623 heterocyclic group Chemical group 0.000 abstract 4
125000000217 alkyl group Chemical group 0.000 abstract 3
-1 12-methylmyristoyl Chemical group 0.000 abstract 2
125000005036 alkoxyphenyl group Chemical group 0.000 abstract 2
150000001412 amines Chemical class 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
ZUOUZKKEUPVFJK-UHFFFAOYSA-N diphenyl Chemical compound C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 abstract 2
125000005842 heteroatom Chemical group 0.000 abstract 2
125000003107 substituted aryl group Chemical group 0.000 abstract 2
YJTKZCDBKVTVBY-UHFFFAOYSA-N 1,3-Diphenylbenzene Chemical group C1=CC=CC=C1C1=CC=CC(C=2C=CC=CC=2)=C1 YJTKZCDBKVTVBY-UHFFFAOYSA-N 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000005037 alkyl phenyl group Chemical group 0.000 abstract 1
125000004103 aminoalkyl group Chemical class 0.000 abstract 1
125000005122 aminoalkylamino group Chemical group 0.000 abstract 1
229940121375 antifungal agent Drugs 0.000 abstract 1
239000003429 antifungal agent Substances 0.000 abstract 1
235000010290 biphenyl Nutrition 0.000 abstract 1
239000004305 biphenyl Substances 0.000 abstract 1
125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
125000002883 imidazolyl group Chemical group 0.000 abstract 1
125000002669 linoleoyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])/C([H])=C([H])\C([H])([H])/C([H])=C([H])\C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
125000001624 naphthyl group Chemical group 0.000 abstract 1
125000001312 palmitoyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
125000006239 protecting group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000000547 substituted alkyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
Communicable Diseases (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

AT00953050T 1999-07-27 2000-07-15 Cyclohexapeptide, deren herstellung und verwendung in pharmazeutische zusammensetzungen ATE416189T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP99114649		1999-07-27

Publications (1)

Publication Number	Publication Date
ATE416189T1 true ATE416189T1 (de)	2008-12-15

Family

ID=8238665

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00953050T ATE416189T1 (de)	1999-07-27	2000-07-15	Cyclohexapeptide, deren herstellung und verwendung in pharmazeutische zusammensetzungen

Country Status (8)

Country	Link
US (1)	US7166572B1 (de)
EP (1)	EP1204677B1 (de)
JP (1)	JP2003505468A (de)
AT (1)	ATE416189T1 (de)
AU (1)	AU6564000A (de)
CA (1)	CA2380176A1 (de)
DE (1)	DE60040989D1 (de)
WO (1)	WO2001007468A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2833596B1 (fr) *	2001-12-14	2005-02-18	Aventis Pharma Sa	Procede de preparation de derives d'echinocandine
US8048853B2 (en)	2008-06-13	2011-11-01	Xellia Pharmaceuticals Aps	Process for preparing pharmaceutical compound and intermediates thereof
US20090324635A1 (en) *	2008-06-25	2009-12-31	Ferenc Korodi	Caspofungin free of caspofungin impurity A
US20100256074A1 (en) *	2008-06-25	2010-10-07	Chaim Eidelman	Processes for preparing high purity aza cyclohexapeptides

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0539088B1 (de) *	1991-10-17	1996-07-17	Merck & Co. Inc.	Echinocandin-B-Derivat
US5914313A (en) *	1991-10-17	1999-06-22	Merck & Co., Inc.	1- 4-hydroxy-5-aminoethyloxy-N2 -(10,12-dimethyl-1-oxotetradecyl)ornithine!-5-(3-hydroxyglutamine)-6-(3-hydroxyproline)echinocandin B, other aminoalkyl derivatives and salts thereof
US5378804A (en)	1993-03-16	1995-01-03	Merck & Co., Inc.	Aza cyclohexapeptide compounds
US5541160A (en) *	1994-04-04	1996-07-30	Merck & Co., Inc.	Antifungal and anti-pneumocystis compounds, compositions containing such compounds, and methods of use
WO1996011210A1 (en) *	1994-10-07	1996-04-18	Fujisawa Pharmaceutical Co., Ltd.	Cyclic hexapeptides having antibiotic activity
CA2211138A1 (en) *	1995-01-26	1996-08-01	Merck & Co., Inc.	Novel antifungal cyclohexapeptides

2000
- 2000-07-15 AT AT00953050T patent/ATE416189T1/de not_active IP Right Cessation
- 2000-07-15 JP JP2001512551A patent/JP2003505468A/ja active Pending
- 2000-07-15 CA CA002380176A patent/CA2380176A1/en not_active Abandoned
- 2000-07-15 US US10/031,764 patent/US7166572B1/en not_active Expired - Fee Related
- 2000-07-15 DE DE60040989T patent/DE60040989D1/de not_active Expired - Fee Related
- 2000-07-15 EP EP00953050A patent/EP1204677B1/de not_active Expired - Lifetime
- 2000-07-15 AU AU65640/00A patent/AU6564000A/en not_active Abandoned
- 2000-07-15 WO PCT/EP2000/006769 patent/WO2001007468A2/en not_active Ceased

Also Published As

Publication number	Publication date
EP1204677B1 (de)	2008-12-03
WO2001007468A2 (en)	2001-02-01
WO2001007468A3 (en)	2001-11-08
CA2380176A1 (en)	2001-02-01
US7166572B1 (en)	2007-01-23
AU6564000A (en)	2001-02-13
EP1204677A2 (de)	2002-05-15
DE60040989D1 (de)	2009-01-15
JP2003505468A (ja)	2003-02-12

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Legal Events

Date	Code	Title	Description
2009-06-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties