ATE141048T1 - Verwendung von polyaminderivaten zur verstärkung der zellularen immunität - Google Patents

Verwendung von polyaminderivaten zur verstärkung der zellularen immunität

Info

Publication number
ATE141048T1
ATE141048T1 AT90109847T AT90109847T ATE141048T1 AT E141048 T1 ATE141048 T1 AT E141048T1 AT 90109847 T AT90109847 T AT 90109847T AT 90109847 T AT90109847 T AT 90109847T AT E141048 T1 ATE141048 T1 AT E141048T1
Authority
AT
Austria
Prior art keywords
cellular immunity
polyamine derivatives
saturated
integer
alkyl
Prior art date
Application number
AT90109847T
Other languages
English (en)
Inventor
Terry L Bowlin
Nellikunja Prakash
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Application granted granted Critical
Publication of ATE141048T1 publication Critical patent/ATE141048T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
AT90109847T 1989-05-23 1990-05-23 Verwendung von polyaminderivaten zur verstärkung der zellularen immunität ATE141048T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US35573689A 1989-05-23 1989-05-23

Publications (1)

Publication Number Publication Date
ATE141048T1 true ATE141048T1 (de) 1996-08-15

Family

ID=23398633

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90109847T ATE141048T1 (de) 1989-05-23 1990-05-23 Verwendung von polyaminderivaten zur verstärkung der zellularen immunität

Country Status (11)

Country Link
EP (1) EP0399519B1 (de)
JP (1) JP2835773B2 (de)
KR (1) KR900017577A (de)
AT (1) ATE141048T1 (de)
AU (1) AU628174B2 (de)
DE (1) DE69028006T2 (de)
DK (1) DK0399519T3 (de)
ES (1) ES2092481T3 (de)
GR (1) GR3021500T3 (de)
IE (1) IE81081B1 (de)
ZA (1) ZA903804B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5561136A (en) * 1990-12-13 1996-10-01 Merrell Pharmaceuticals Inc. Method of treating cancer by conjunctive therapy with N,N'-bis[ethylamino)propyl]-1,7-heptanediamine and a cytotoxic agent
ZA919695B (en) * 1990-12-13 1992-09-30 Merrell Dow Pharma Method of treating cancer by conjunctive therapy with n,n'-bis(3-(ethylamino)propyl)-1,7-heptanediamine and a cytotoxic agent
GB9220921D0 (en) * 1992-10-05 1992-11-18 Merrell Dow Pharma Polyamine derivatives as anticytomegaloviral agents
US5929039A (en) * 1993-11-15 1999-07-27 Baker Medical Research Institute Method for treating cardiac dysfunction and pharmaceutical compositions useful therefor
FR2724379B1 (fr) * 1994-09-13 1996-11-29 Fournier Sca Lab Procede de fabrication de polyamines qui sont des homologues structuraux de la spermidine.
US5516807A (en) * 1994-10-25 1996-05-14 Warner-Lambert Company Method for treating vascular proliferative disorders following balloon angioplasty
AU2003231670B2 (en) * 1997-10-27 2006-06-08 Slil Biomedical Corporation Methods for modulating macrophage proliferation using polyamine analogs
US8198334B2 (en) 1997-10-27 2012-06-12 Pathologica Llc Methods for modulating macrophage proliferation in ocular disease using polyamine analogs
US7087648B1 (en) * 1997-10-27 2006-08-08 The Regents Of The University Of California Methods for modulating macrophage proliferation using polyamine analogs
HUP0400494A3 (en) * 2000-03-24 2004-08-30 Mediquest Therapeutics Inc Sea Polyamine analogues as cytotoxic agents and pharmaceutical compositions containing them
US6919483B2 (en) * 2003-05-23 2005-07-19 Mediquest Therapeutics, Inc. Immunomodulation with novel pharmaceutical compositions
AU2019213664B2 (en) * 2018-01-30 2023-03-16 Panbela Therapeutics, Inc. Methods for producing (6S,15S)-3,8,13,18-tetraazaicosane-6,15-diol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5998015A (ja) * 1982-11-27 1984-06-06 Microbial Chem Res Found 免疫賦活剤
NZ212053A (en) * 1984-05-17 1988-02-29 Merrell Dow Pharma Polyamine containing pharmaceutical compositions for treating neoplasms
JPS62263127A (ja) * 1986-05-06 1987-11-16 メレルダウフア−マス−テイカルズ　インコ−ポレ−テツド 自己由来のｌａｋ細胞、インタ−ロイキン−２、及びオルニチンデカルボキシラ−ゼ阻害剤による腫瘍の処置
ZA88600B (en) * 1987-02-03 1988-07-28 Merrell Dow Pharmaceuticals Inc. Novel polyamine derivatives

Also Published As

Publication number Publication date
KR900017577A (ko) 1990-12-19
IE901845L (en) 1990-11-23
ES2092481T3 (es) 1996-12-01
JPH035420A (ja) 1991-01-11
AU5517190A (en) 1990-11-29
GR3021500T3 (en) 1997-01-31
EP0399519A2 (de) 1990-11-28
ZA903804B (en) 1991-03-27
JP2835773B2 (ja) 1998-12-14
IE81081B1 (en) 2000-02-23
AU628174B2 (en) 1992-09-10
EP0399519A3 (de) 1991-12-04
DK0399519T3 (da) 1996-09-02
EP0399519B1 (de) 1996-08-07
DE69028006T2 (de) 1997-03-20
DE69028006D1 (de) 1996-09-12

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee