ATE141284T1 - Verfahren zur herstellung von hochreinem fibrinogen - Google Patents

Verfahren zur herstellung von hochreinem fibrinogen

Info

Publication number: ATE141284T1
Authority: AT; Austria
Prior art keywords: fibrinogen; solution; ionic strength; high purity; agarose
Prior art date: 1992-02-04

Application number

AT93400247T

Other languages

English (en)

Inventor

Bernard Dazey

Mohamed Hamsany

Sylvia Enfedaque-Morer

Gerard Vezon

Original Assignee

Aquitaine Dev Transf Sanguine

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-02-04

Filing date

1993-02-02

Publication date

1996-08-15

1993-02-02 Application filed by Aquitaine Dev Transf Sanguine filed Critical Aquitaine Dev Transf Sanguine

1996-08-15 Application granted granted Critical

1996-08-15 Publication of ATE141284T1 publication Critical patent/ATE141284T1/de

Links

102000008946 Fibrinogen Human genes 0.000 title abstract 5
108010049003 Fibrinogen Proteins 0.000 title abstract 5
229940012952 fibrinogen Drugs 0.000 title abstract 5
238000004519 manufacturing process Methods 0.000 title abstract 2
FBPFZTCFMRRESA-ZXXMMSQZSA-N D-iditol Chemical compound OC[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-ZXXMMSQZSA-N 0.000 title 1
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 4
239000000243 solution Substances 0.000 abstract 4
229920000936 Agarose Polymers 0.000 abstract 3
238000005349 anion exchange Methods 0.000 abstract 2
239000011324 bead Substances 0.000 abstract 2
239000011780 sodium chloride Substances 0.000 abstract 2
125000003161 (C1-C6) alkylene group Chemical group 0.000 abstract 1
239000007983 Tris buffer Substances 0.000 abstract 1
125000003277 amino group Chemical group 0.000 abstract 1
239000007864 aqueous solution Substances 0.000 abstract 1
239000007853 buffer solution Substances 0.000 abstract 1
238000010828 elution Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
210000002381 plasma Anatomy 0.000 abstract 1
125000006850 spacer group Chemical group 0.000 abstract 1
LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/75—Fibrinogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Zoology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Hematology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Materials For Medical Uses (AREA)
Compounds Of Unknown Constitution (AREA)

AT93400247T 1992-02-04 1993-02-02 Verfahren zur herstellung von hochreinem fibrinogen ATE141284T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9201238A FR2686883B1 (fr)	1992-02-04	1992-02-04	Procede de fabrication de fibrinogene de tres haute purete, fibrinogene de tres haute purete obtenu ainsi qu'une composition pharmaceutique le contenant.

Publications (1)

Publication Number	Publication Date
ATE141284T1 true ATE141284T1 (de)	1996-08-15

Family

ID=9426316

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT93400247T ATE141284T1 (de)	1992-02-04	1993-02-02	Verfahren zur herstellung von hochreinem fibrinogen

Country Status (7)

Country	Link
EP (1)	EP0555135B1 (de)
AT (1)	ATE141284T1 (de)
DE (2)	DE69303941T2 (de)
DK (1)	DK0555135T3 (de)
ES (1)	ES2049701T3 (de)
FR (1)	FR2686883B1 (de)
GR (2)	GR930300095T1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0602173B1 (de) *	1991-09-05	1999-05-26	Baxter International Inc.	Topischer fibrinogenkomplex
ATE184884T1 (de) *	1994-07-14	1999-10-15	Croix Rouge De Belgique	Fibrinogenkonzentrate aus blutplasma, verfahren und anlage für ihre herstellung
DE10261126A1 (de) *	2002-08-13	2004-03-04	Aventis Behring Gmbh	Lagerungsstabile, flüssige Fibrinogen-Formulierung
DE102004009400A1 (de)	2004-02-24	2005-09-08	Zlb Behring Gmbh	Fibrinogen Reinigung
FR2887883B1 (fr)	2005-06-29	2007-08-31	Lab Francais Du Fractionnement	Procede de separation des proteines fibrinogene, facteur xiii et colle biologique d'une fraction plasmatique solubilisee et de preparation de concentres lyophilises desdites proteines
CA2728358C (en)	2008-06-23	2016-06-14	Bio-Products & Bio-Engineering Ag	Storage-stable, functionally intact fibrinogen
EP2619225B1 (de) *	2010-09-20	2016-06-15	Octapharma AG	Verfahren zur herstellung von fibrinogen
US10112972B2 (en)	2012-03-13	2018-10-30	Octapharma Ag	Process for production of fibrinogen and fibrinogen produced thereby
US10188965B2 (en)	2012-12-05	2019-01-29	Csl Behring Gmbh	Hydrophobic charge induction chromatographic depletion of a protein from a solution
US20140154233A1 (en)	2012-12-05	2014-06-05	Csl Limited	Method of purifying therapeutic proteins

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2632309B1 (fr) *	1988-06-07	1990-08-24	Lille Transfusion Sanguine	Procede de purification par voie chromatographique de proteines, notamment de facteur viii, et les produits obtenus
FR2644064B1 (fr) *	1989-02-17	1994-05-27	Aquitaine Dev Transf Sanguine	Procede de fabrication du facteur antihemophilique fviiic ayant une tres haute purete et facteur antihemophilique fviiic ainsi obtenu, ainsi que composition pharmaceutique le contenant
IT1248723B (it) *	1990-06-12	1995-01-26	Scalvo S P A	Processo per la purificazione del fattore viii e fattore viii ottenuto con tale processo

1992
- 1992-02-04 FR FR9201238A patent/FR2686883B1/fr not_active Expired - Fee Related
1993
- 1993-02-02 ES ES93400247T patent/ES2049701T3/es not_active Expired - Lifetime
- 1993-02-02 DE DE69303941T patent/DE69303941T2/de not_active Expired - Fee Related
- 1993-02-02 DK DK93400247.8T patent/DK0555135T3/da active
- 1993-02-02 EP EP93400247A patent/EP0555135B1/de not_active Expired - Lifetime
- 1993-02-02 DE DE93400247T patent/DE555135T1/de active Pending
- 1993-02-02 AT AT93400247T patent/ATE141284T1/de not_active IP Right Cessation
- 1993-09-30 GR GR930300095T patent/GR930300095T1/el unknown
1996
- 1996-10-23 GR GR960402791T patent/GR3021419T3/el unknown

Also Published As

Publication number	Publication date
FR2686883B1 (fr)	1994-05-13
DE555135T1 (de)	1994-03-31
DE69303941T2 (de)	1997-03-27
DE69303941D1 (de)	1996-09-19
ES2049701T3 (es)	1997-01-16
GR3021419T3 (en)	1997-01-31
GR930300095T1 (en)	1993-09-30
DK0555135T3 (da)	1996-11-25
EP0555135B1 (de)	1996-08-14
ES2049701T1 (es)	1994-05-01
EP0555135A1 (de)	1993-08-11
FR2686883A1 (fr)	1993-08-06

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Legal Events

Date	Code	Title	Description
2009-11-15	REN	Ceased due to non-payment of the annual fee