ATE141603T1 - Pyrrolopyrimidine, ihre herstellung und verwendung als tumorizide wirkstoffe - Google Patents

Pyrrolopyrimidine, ihre herstellung und verwendung als tumorizide wirkstoffe

Info

Publication number
ATE141603T1
ATE141603T1 AT90110131T AT90110131T ATE141603T1 AT E141603 T1 ATE141603 T1 AT E141603T1 AT 90110131 T AT90110131 T AT 90110131T AT 90110131 T AT90110131 T AT 90110131T AT E141603 T1 ATE141603 T1 AT E141603T1
Authority
AT
Austria
Prior art keywords
group
substituent
formula
hydrogen atom
optionally
Prior art date
Application number
AT90110131T
Other languages
English (en)
Inventor
Hiroshi Akimoto
Takenori Hitaka
Tetsuo Miwa
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ATE141603T1 publication Critical patent/ATE141603T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT90110131T 1989-05-29 1990-05-29 Pyrrolopyrimidine, ihre herstellung und verwendung als tumorizide wirkstoffe ATE141603T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP13564289 1989-05-29
JP24620989 1989-09-20
JP9337090 1990-04-09

Publications (1)

Publication Number Publication Date
ATE141603T1 true ATE141603T1 (de) 1996-09-15

Family

ID=27307272

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90110131T ATE141603T1 (de) 1989-05-29 1990-05-29 Pyrrolopyrimidine, ihre herstellung und verwendung als tumorizide wirkstoffe

Country Status (5)

Country Link
EP (1) EP0400562B1 (de)
JP (1) JP3015957B2 (de)
AT (1) ATE141603T1 (de)
CA (1) CA2017604A1 (de)
DE (1) DE69028140T2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2057635A1 (en) * 1990-12-14 1992-06-15 Hiroshi Akimoto Condensed heterocyclic compounds, their production and use
DE69216509T2 (de) * 1991-08-12 1997-05-28 Takeda Chemical Industries Ltd Kondensierte Pyrimidinderivate, ihre Herstellung und ihre Verwendung als Antitumormittel
EP0549291A1 (de) * 1991-12-27 1993-06-30 Takeda Chemical Industries, Ltd. Thymidylate Synthase-Inhibitoren
JP3264465B2 (ja) 1993-06-30 2002-03-11 株式会社日立製作所 記憶システム
WO1998008382A1 (en) * 1996-08-30 1998-03-05 Eli Lilly And Company Nonclassical pyrrolo[2,3-d]pyrimidine antifolates
KR20130099013A (ko) 2010-07-30 2013-09-05 다우 코닝 도레이 캄파니 리미티드 당 알콜-개질된 실리콘을 함유한 모발용 화장료

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3276808D1 (de) * 1981-09-25 1987-08-27 Southern Res Inst Pyrido (2,3-d) pyrimidines
JPS58126887A (ja) * 1981-09-26 1983-07-28 Takeda Chem Ind Ltd 新規７−デアザプリン誘導体
US4532241A (en) * 1982-08-26 1985-07-30 Sri International 8,10-Dideazaminopterins
US4684653A (en) * 1985-03-08 1987-08-04 The Trustees Of Princeton University Pyrido(2,3-d)pyrimidine derivatives
IE60038B1 (en) * 1986-06-30 1994-05-18 Univ Princeton 4(3H)-oxo-5, 6, 7, 8-tetrahydropyrido-[2, 3-d]pyrimidine derivatives
NO169490C (no) * 1988-03-24 1992-07-01 Takeda Chemical Industries Ltd Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrrolopyrimidinderivater

Also Published As

Publication number Publication date
JPH049382A (ja) 1992-01-14
EP0400562B1 (de) 1996-08-21
CA2017604A1 (en) 1990-11-29
EP0400562A1 (de) 1990-12-05
JP3015957B2 (ja) 2000-03-06
DE69028140D1 (de) 1996-09-26
DE69028140T2 (de) 1997-02-20

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Legal Events

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