ATE142202T1 - Acridinone als chromogene enzymsubstrate - Google Patents

Acridinone als chromogene enzymsubstrate

Info

Publication number
ATE142202T1
ATE142202T1 AT91113550T AT91113550T ATE142202T1 AT E142202 T1 ATE142202 T1 AT E142202T1 AT 91113550 T AT91113550 T AT 91113550T AT 91113550 T AT91113550 T AT 91113550T AT E142202 T1 ATE142202 T1 AT E142202T1
Authority
AT
Austria
Prior art keywords
enzyme
hydroxy
enzyme substrate
acridin
enzymatically
Prior art date
Application number
AT91113550T
Other languages
English (en)
Inventor
Paul F Corey
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of ATE142202T1 publication Critical patent/ATE142202T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/40Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving amylase
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D219/00Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/06Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20Spiro-condensed ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576Six-membered rings
    • C07F9/64Acridine or hydrogenated acridine ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02Heterocyclic radicals containing only nitrogen as ring hetero atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/54Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2334/00O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/924Hydrolases (3) acting on glycosyl compounds (3.2)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/805Test papers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Emergency Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Saccharide Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT91113550T 1986-12-09 1987-11-27 Acridinone als chromogene enzymsubstrate ATE142202T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US93985586A 1986-12-09 1986-12-09

Publications (1)

Publication Number Publication Date
ATE142202T1 true ATE142202T1 (de) 1996-09-15

Family

ID=25473855

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91113550T ATE142202T1 (de) 1986-12-09 1987-11-27 Acridinone als chromogene enzymsubstrate

Country Status (11)

Country Link
EP (1) EP0459536B1 (de)
JP (1) JPH0662569B2 (de)
AT (1) ATE142202T1 (de)
AU (1) AU585472B2 (de)
DE (2) DE3779066D1 (de)
DK (1) DK643887A (de)
ES (1) ES2091267T3 (de)
IE (1) IE60183B1 (de)
IL (1) IL84666A (de)
NO (1) NO175308C (de)
ZA (1) ZA879223B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7183069B2 (en) 2002-03-07 2007-02-27 Toyama University Reagent, method and apparatus for measuring amylase activity
US7186696B2 (en) 2002-03-07 2007-03-06 Toyama University Reagent and method for measuring amylase
FR2850378B1 (fr) * 2003-01-29 2005-03-04 Bio Merieux Substrats enzymatiques, milieux de culture les contenant, utilisation pour detecter une activite aminopeptidase et/ou differencier des bacteries a gram+ par rapport a des bacteries a gram-
WO2006034036A1 (en) 2004-09-16 2006-03-30 Applera Corporation Fluorescent dye compounds, conjugates and uses thereof
WO2012092403A1 (en) 2010-12-29 2012-07-05 Life Technologies Corporation Ddao compounds as fluorescent reference standards

Also Published As

Publication number Publication date
EP0459536A1 (de) 1991-12-04
IL84666A (en) 1992-02-16
IE873331L (en) 1988-06-09
NO175308B (no) 1994-06-20
DE3751896D1 (de) 1996-10-10
IL84666A0 (en) 1988-05-31
NO875008D0 (no) 1987-12-01
ZA879223B (en) 1988-08-31
DE3779066D1 (en) 1992-06-17
AU585472B2 (en) 1989-06-15
IE60183B1 (en) 1994-06-15
NO175308C (no) 1994-09-28
DK643887D0 (da) 1987-12-08
DE3751896T2 (de) 1997-01-16
ES2091267T3 (es) 1996-11-01
NO875008L (no) 1988-06-10
EP0459536B1 (de) 1996-09-04
JPH01131192A (ja) 1989-05-24
AU8206087A (en) 1988-06-09
JPH0662569B2 (ja) 1994-08-17
DK643887A (da) 1988-06-10

Similar Documents

Publication Publication Date Title
ATE76068T1 (de) Acridinone als chromogene enzymsubstrate.
ATE113664T1 (de) Zusammensetzung, vorrichtung und verfahren zur untersuchung einer peroxidativ aktiven substanz.
AU623038B2 (en) Improved composition, device and method of assaying for peroxidatively active substances
DK0649535T3 (da) Fremgangsmåde til at forbedre målepræcisionen i optisk biosensor assays med detektering af rumligt dæmpede bølger
DK351983D0 (da) Komposition, testmateriale og fremgangsmade til detektering af naervaerelsen og/eller bestemmelse af koncentrationen af glucose i en forsoegsproeve
JPS56134999A (en) Method and reagent for measuring biological activity of heparin in serum
ATE142202T1 (de) Acridinone als chromogene enzymsubstrate
CA1265424C (en) FLUOROGENIC INDICATORS BASED ON DIHYDROQUINOLONE AND DIHYDROCOUMARIN FOR HYDROGEN PEROXIDE
DE3663684D1 (de) Determination of prokallikrein
ZA906998B (en) Process and reagent for the specific determination of pancreatic alpha-amylase
SE8402305L (sv) Sett att bestemma katepsin b i nervaro av andra proteolytiska enzymer, och dertill anvendbara foreningar
JPS5794300A (en) Novel measuring method
JPS5736997A (ja) Anjiotenshinhenkankosonokatsuseisokuteiho
ES469000A3 (es) Un metodo fluorometrico para la determinacion de la activi- dad de transferasas y proteasas en muestras de fluidos bio- logicos

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee