ATE142493T1 - Derivate des hydantoins zur verwendung als hypoglycemische und/oder hypolipidemische wirkstoffe - Google Patents
Derivate des hydantoins zur verwendung als hypoglycemische und/oder hypolipidemische wirkstoffeInfo
- Publication number
- ATE142493T1 ATE142493T1 AT91102632T AT91102632T ATE142493T1 AT E142493 T1 ATE142493 T1 AT E142493T1 AT 91102632 T AT91102632 T AT 91102632T AT 91102632 T AT91102632 T AT 91102632T AT E142493 T1 ATE142493 T1 AT E142493T1
- Authority
- AT
- Austria
- Prior art keywords
- present
- hydantoin
- compounds
- hypoglycemic
- hypolipidemic
- Prior art date
Links
- WJRBRSLFGCUECM-UHFFFAOYSA-N hydantoin Chemical class O=C1CNC(=O)N1 WJRBRSLFGCUECM-UHFFFAOYSA-N 0.000 title abstract 3
- 230000002218 hypoglycaemic effect Effects 0.000 title abstract 3
- 230000000055 hyoplipidemic effect Effects 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 4
- 230000002265 prevention Effects 0.000 abstract 3
- 208000031226 Hyperlipidaemia Diseases 0.000 abstract 2
- 206010061666 Autonomic neuropathy Diseases 0.000 abstract 1
- 208000002177 Cataract Diseases 0.000 abstract 1
- 208000002249 Diabetes Complications Diseases 0.000 abstract 1
- 206010012655 Diabetic complications Diseases 0.000 abstract 1
- 208000017442 Retinal disease Diseases 0.000 abstract 1
- 206010038923 Retinopathy Diseases 0.000 abstract 1
- 239000003472 antidiabetic agent Substances 0.000 abstract 1
- 229940053195 antiepileptics hydantoin derivative Drugs 0.000 abstract 1
- 239000003524 antilipemic agent Substances 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 229940091173 hydantoin Drugs 0.000 abstract 1
- 150000001469 hydantoins Chemical class 0.000 abstract 1
- 208000017169 kidney disease Diseases 0.000 abstract 1
- 206010062198 microangiopathy Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000000392 somatic effect Effects 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B14/00—Arrangements for collecting, re-using or eliminating excess spraying material
- B05B14/30—Arrangements for collecting, re-using or eliminating excess spraying material comprising enclosures close to, or in contact with, the object to be sprayed and surrounding or confining the discharged spray or jet but not the object to be sprayed
Landscapes
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2043420A JP2673381B2 (ja) | 1990-02-23 | 1990-02-23 | 糖尿病前症治療剤および/または脂質低下剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE142493T1 true ATE142493T1 (de) | 1996-09-15 |
Family
ID=12663213
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91102632T ATE142493T1 (de) | 1990-02-23 | 1991-02-22 | Derivate des hydantoins zur verwendung als hypoglycemische und/oder hypolipidemische wirkstoffe |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0444546B1 (de) |
| JP (1) | JP2673381B2 (de) |
| KR (1) | KR100189708B1 (de) |
| AT (1) | ATE142493T1 (de) |
| AU (1) | AU633694B2 (de) |
| CA (1) | CA2036902A1 (de) |
| DE (1) | DE69121940T2 (de) |
| DK (1) | DK0444546T3 (de) |
| WO (1) | WO1991012803A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0600973A1 (de) * | 1991-08-27 | 1994-06-15 | The Upjohn Company | Verfahren zur behandlung von störungen des metabolismus |
| US6337340B1 (en) * | 1998-08-14 | 2002-01-08 | Gpi Nil Holdings, Inc. | Carboxylic acids and isosteres of heterocyclic ring compounds having multiple heteroatoms for vision and memory disorders |
| AU754989B2 (en) * | 1998-11-16 | 2002-11-28 | Nippon Zoki Pharmaceutical Co., Ltd. | A therapeutic agent for intractable vasculitis |
| EP1299362A4 (de) * | 2000-07-05 | 2004-11-03 | Synaptic Pharma Corp | Selektive rezeptorantagonisten des melaninkonzentrierenden hormons-1 (mch1) und ihre anwendung |
| JP4711523B2 (ja) * | 2001-02-13 | 2011-06-29 | 日本臓器製薬株式会社 | 低アルブミン血症改善剤 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4743611A (en) * | 1986-07-02 | 1988-05-10 | American Home Products Corp. | Naphthalenylsulfonylimidazolidinediones and their thioxo analogs useful as aldose reductase inhibitors |
| JPS6322565A (ja) * | 1986-07-02 | 1988-01-30 | アメリカン・ホ−ム・プロダクツ・コ−ポレイシヨン | アルド−スレダクタ−ゼ抑制剤として有用なナフタレニルスルホニルイミダゾリジンジオンおよびそのチオキソ類似体 |
| JP2764262B2 (ja) * | 1987-08-28 | 1998-06-11 | 持田製薬株式会社 | ヒダントイン誘導体及びそれを有効成分とする医薬組成物 |
| JPH0615539B2 (ja) * | 1988-08-24 | 1994-03-02 | 持田製薬株式会社 | ヒダントイン誘導体及びそれを有効成分とする医薬組成物 |
| FI902028A7 (fi) * | 1988-08-24 | 1990-04-23 | Mochida Pharm Co Ltd | Hydantoiinijohdannaisia |
-
1990
- 1990-02-23 JP JP2043420A patent/JP2673381B2/ja not_active Expired - Lifetime
-
1991
- 1991-02-22 DE DE69121940T patent/DE69121940T2/de not_active Expired - Fee Related
- 1991-02-22 KR KR1019910701403A patent/KR100189708B1/ko not_active Expired - Fee Related
- 1991-02-22 EP EP91102632A patent/EP0444546B1/de not_active Expired - Lifetime
- 1991-02-22 AU AU71313/91A patent/AU633694B2/en not_active Ceased
- 1991-02-22 AT AT91102632T patent/ATE142493T1/de active
- 1991-02-22 DK DK91102632.6T patent/DK0444546T3/da active
- 1991-02-22 CA CA002036902A patent/CA2036902A1/en not_active Abandoned
- 1991-02-22 WO PCT/JP1991/000226 patent/WO1991012803A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CA2036902A1 (en) | 1991-08-24 |
| JPH03294270A (ja) | 1991-12-25 |
| WO1991012803A1 (en) | 1991-09-05 |
| DE69121940D1 (de) | 1996-10-17 |
| DE69121940T2 (de) | 1997-02-20 |
| KR100189708B1 (ko) | 1999-06-01 |
| AU7131391A (en) | 1991-02-22 |
| EP0444546A1 (de) | 1991-09-04 |
| DK0444546T3 (da) | 1996-09-30 |
| EP0444546B1 (de) | 1996-09-11 |
| JP2673381B2 (ja) | 1997-11-05 |
| KR920700640A (ko) | 1992-08-10 |
| AU633694B2 (en) | 1993-02-04 |
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