ATE142496T1 - Verwendung von n-butyl-deoxynojirimycin zur behandlung von herpes - Google Patents
Verwendung von n-butyl-deoxynojirimycin zur behandlung von herpesInfo
- Publication number
- ATE142496T1 ATE142496T1 AT89870206T AT89870206T ATE142496T1 AT E142496 T1 ATE142496 T1 AT E142496T1 AT 89870206 T AT89870206 T AT 89870206T AT 89870206 T AT89870206 T AT 89870206T AT E142496 T1 ATE142496 T1 AT E142496T1
- Authority
- AT
- Austria
- Prior art keywords
- deoxynojirimycin
- butyl
- treat herpes
- herpes
- treat
- Prior art date
Links
- XQFRJNBWHJMXHO-RRKCRQDMSA-N IDUR Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C(I)=C1 XQFRJNBWHJMXHO-RRKCRQDMSA-N 0.000 title 1
- UQRORFVVSGFNRO-UTINFBMNSA-N miglustat Chemical compound CCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO UQRORFVVSGFNRO-UTINFBMNSA-N 0.000 title 1
- 229960001512 miglustat Drugs 0.000 title 1
- LXBIFEVIBLOUGU-UHFFFAOYSA-N Deoxymannojirimycin Natural products OCC1NCC(O)C(O)C1O LXBIFEVIBLOUGU-UHFFFAOYSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 241001529453 unidentified herpesvirus Species 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/288,528 US4957926A (en) | 1988-12-22 | 1988-12-22 | Method of treating herpesviruses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE142496T1 true ATE142496T1 (de) | 1996-09-15 |
Family
ID=23107522
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89870206T ATE142496T1 (de) | 1988-12-22 | 1989-12-21 | Verwendung von n-butyl-deoxynojirimycin zur behandlung von herpes |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4957926A (de) |
| EP (1) | EP0378984B1 (de) |
| JP (1) | JP2831068B2 (de) |
| AT (1) | ATE142496T1 (de) |
| CA (1) | CA2006267C (de) |
| DE (1) | DE68927160T2 (de) |
| ES (1) | ES2091766T3 (de) |
| GR (1) | GR3021845T3 (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5252587A (en) * | 1990-04-27 | 1993-10-12 | Merrell Dow Pharmaceuticals, Inc. | N-derivatives of 1-deoxy nojirimycin |
| US5536732A (en) * | 1990-04-27 | 1996-07-16 | Merrell Pharmaceuticals Inc. | N-derivatives of 1-deoxy nojirimycin |
| US5258518A (en) * | 1992-04-01 | 1993-11-02 | G. D. Searle & Co. | 2-substituted tertiary carbinol derivatives of deoxynojirimycin |
| US5268482A (en) * | 1992-04-01 | 1993-12-07 | G. D. Searle & Co. | 2- and 3-sulfur derivatives of 1,5-iminosugars |
| US5331096A (en) * | 1992-04-01 | 1994-07-19 | G. D. Searle & Co. | 2- and 3-sulfur derivatives of 1,5-iminosugars |
| US5342951A (en) * | 1992-04-01 | 1994-08-30 | G.D. Searle & Co. | 2- and 3-sulfur derivatives of 1,5-iminosugars |
| US5216168A (en) * | 1992-04-01 | 1993-06-01 | G. D. Searle & Co. | 2- and 3- amino and azido derivatives of 1,5-iminosugars |
| US5206251A (en) * | 1992-04-01 | 1993-04-27 | G. D. Searle & Co. | 2- and 3- amino and azido derivatives of 1,5-iminosugars |
| JP3628021B2 (ja) * | 1994-01-13 | 2005-03-09 | ジー.ディー.サール アンド カンパニー | B型肝炎ウイルス感染症の治療のための1,5−ジデオキシ−1,5−イミノ−d−グルシトールのn−アルキル誘導体の使用 |
| WO1995022975A1 (en) * | 1994-02-25 | 1995-08-31 | G.D. Searle & Co. | Use of 1-deoxynojirimycin and its derivatives for treating mammals infected with respiratory syncytial virus |
| US20030100532A1 (en) | 1997-02-14 | 2003-05-29 | Gary S. Jacob | Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy for treating hepatitis virus infections |
| ZA9810210B (en) | 1997-11-10 | 1999-07-14 | Searle & Co | Use of alkylated iminosugars to treat multidrug resistance. |
| ATE331515T1 (de) | 1998-02-12 | 2006-07-15 | Searle Llc | Verwendung von n-substituirten-1,5-dideoxy-1,5- imino-d-glucitolen zur behandlung von hepatitis infektionen |
| US6689759B1 (en) | 1998-02-12 | 2004-02-10 | G. D. Searle & Co. | Methods of Treating hepatitis virus infections with N-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy |
| ES2311921T3 (es) * | 1999-02-12 | 2009-02-16 | United Therapeutics Corporation | N-(8,8,8-trifluorooctil)1-5,-didesoxi-1,5-imino-d-glucitol para tratar infecciones por el virus de la hepatitis. |
| AU3858600A (en) | 1999-02-12 | 2001-02-19 | G.D. Searle & Co. | Glucamine compounds for treating hepatitis virus infections |
| CN1422156A (zh) * | 2000-02-14 | 2003-06-04 | 法马西亚公司 | N-取代的-1,5-二脱氧-1,5-亚氨基-d-葡萄糖醇化合物在治疗肝炎病毒感染中的用途 |
| KR100446483B1 (ko) | 2000-03-31 | 2004-09-01 | 미시간 스테이트 유니버시티 | 옥심 또는 이민으로부터 1,5-디데옥시-1,5-이미노 헥시톨제조방법 |
| WO2008045015A1 (en) | 2005-06-08 | 2008-04-17 | Amicus Therapeutics, Inc. | Imino and amino sugar purification |
| US8097728B2 (en) * | 2007-04-30 | 2012-01-17 | Philadelphia Health & Education Corporation | Iminosugar compounds with antiflavirus activity |
| IT201700078102A1 (it) | 2017-07-11 | 2019-01-11 | Dipharma Francis Srl | Sintesi di un azazucchero e suoi intermedi |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1555654A (en) * | 1977-06-25 | 1979-11-14 | Exxon Research Engineering Co | Agricultural burner apparatus |
| NO154918C (no) * | 1977-08-27 | 1987-01-14 | Bayer Ag | Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin. |
| ATE126696T1 (de) * | 1985-12-23 | 1995-09-15 | Hutchinson Fred Cancer Res | Regulierung der retroviralen replikation, infektion und pathogenese. |
-
1988
- 1988-12-22 US US07/288,528 patent/US4957926A/en not_active Expired - Lifetime
-
1989
- 1989-12-21 JP JP1332489A patent/JP2831068B2/ja not_active Expired - Fee Related
- 1989-12-21 ES ES89870206T patent/ES2091766T3/es not_active Expired - Lifetime
- 1989-12-21 CA CA002006267A patent/CA2006267C/en not_active Expired - Fee Related
- 1989-12-21 EP EP89870206A patent/EP0378984B1/de not_active Expired - Lifetime
- 1989-12-21 DE DE68927160T patent/DE68927160T2/de not_active Expired - Fee Related
- 1989-12-21 AT AT89870206T patent/ATE142496T1/de not_active IP Right Cessation
-
1996
- 1996-11-29 GR GR960403244T patent/GR3021845T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE68927160T2 (de) | 1997-03-20 |
| EP0378984A2 (de) | 1990-07-25 |
| CA2006267A1 (en) | 1990-06-22 |
| CA2006267C (en) | 2000-05-02 |
| GR3021845T3 (en) | 1997-02-28 |
| DE68927160D1 (de) | 1996-10-17 |
| JPH02212430A (ja) | 1990-08-23 |
| US4957926A (en) | 1990-09-18 |
| EP0378984A3 (de) | 1992-07-08 |
| JP2831068B2 (ja) | 1998-12-02 |
| EP0378984B1 (de) | 1996-09-11 |
| ES2091766T3 (es) | 1996-11-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |