DK0739205T3 - Anvendelse af N-alkylderivater af 1,5-didesoxy-1,5-imino-D-glucitol til behandling af hepatitis-B-virusinfektioner - Google Patents
Anvendelse af N-alkylderivater af 1,5-didesoxy-1,5-imino-D-glucitol til behandling af hepatitis-B-virusinfektionerInfo
- Publication number
- DK0739205T3 DK0739205T3 DK95905416T DK95905416T DK0739205T3 DK 0739205 T3 DK0739205 T3 DK 0739205T3 DK 95905416 T DK95905416 T DK 95905416T DK 95905416 T DK95905416 T DK 95905416T DK 0739205 T3 DK0739205 T3 DK 0739205T3
- Authority
- DK
- Denmark
- Prior art keywords
- glucitol
- imino
- hepatitis
- treatment
- pct
- Prior art date
Links
- 208000002672 hepatitis B Diseases 0.000 title 1
- 229960002920 sorbitol Drugs 0.000 title 1
- LXBIFEVIBLOUGU-UHFFFAOYSA-N Deoxymannojirimycin Natural products OCC1NCC(O)C(O)C1O LXBIFEVIBLOUGU-UHFFFAOYSA-N 0.000 abstract 1
- 241000700721 Hepatitis B virus Species 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18151994A | 1994-01-13 | 1994-01-13 | |
| PCT/US1994/014548 WO1995019172A1 (en) | 1994-01-13 | 1994-12-23 | Use of n-alkyl derivatives of 1,5-dideoxy-1,5-imino-d-glucitol for the treatment of hepatitis b virus infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0739205T3 true DK0739205T3 (da) | 2000-05-01 |
Family
ID=22664619
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95905416T DK0739205T3 (da) | 1994-01-13 | 1994-12-23 | Anvendelse af N-alkylderivater af 1,5-didesoxy-1,5-imino-D-glucitol til behandling af hepatitis-B-virusinfektioner |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US6037351A (da) |
| EP (1) | EP0739205B1 (da) |
| JP (1) | JP3628021B2 (da) |
| KR (1) | KR100348657B1 (da) |
| CN (1) | CN1074921C (da) |
| AT (1) | ATE186836T1 (da) |
| AU (1) | AU1403795A (da) |
| CA (1) | CA2181033C (da) |
| DE (1) | DE69421828T2 (da) |
| DK (1) | DK0739205T3 (da) |
| ES (1) | ES2140652T3 (da) |
| GR (1) | GR3032527T3 (da) |
| PT (1) | PT739205E (da) |
| WO (1) | WO1995019172A1 (da) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030100532A1 (en) * | 1997-02-14 | 2003-05-29 | Gary S. Jacob | Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy for treating hepatitis virus infections |
| DK1030839T3 (da) | 1997-11-10 | 2004-05-03 | Searle & Co | Anvendelse af alkylerede iminosukkere til behandling af multidrugresistens |
| US6809083B1 (en) * | 1998-02-12 | 2004-10-26 | Richard A. Mueller | Use of N-substituted-1, 5-dideoxy-1, 5-imino-D-glucitol compounds for treating hepatitis virus infections |
| US6689759B1 (en) | 1998-02-12 | 2004-02-10 | G. D. Searle & Co. | Methods of Treating hepatitis virus infections with N-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy |
| EP1714676A3 (en) * | 1998-02-12 | 2006-11-15 | G.D. Searle LLC. | Use of N-substituted-1,5-dideoxy-1,5-imino-D-glucitol compounds for treating hepatitis virus infections |
| US6274597B1 (en) | 1998-06-01 | 2001-08-14 | Mount Sinai School Of Medicine Of New York University | Method of enhancing lysosomal α-Galactosidase A |
| ATE402701T1 (de) * | 1999-02-12 | 2008-08-15 | United Therapeutics Corp | N-(8,8,8-trifluorooctyl)-1,5-dideoxy-1,5-imino- - glucitol zur behandlung von hepatitis-virus- infektionen |
| JP2003505501A (ja) | 1999-02-12 | 2003-02-12 | ジー・ディー・サール・アンド・カンパニー | 肝炎ウィルス感染の処置のためのグルカミン化合物 |
| EP1658846B1 (en) * | 1999-02-12 | 2008-07-30 | United Therapeutics Corporation | N-(8,8,8-trifluorooctyl)-1,5-dideoxy-1,5-imino-D-glucitol for treating hepatitis virus infections |
| ES2302697T3 (es) | 1999-08-10 | 2008-08-01 | The Chancellor, Masters And Scholars Of The University Of Oxford | Compuestos n-alquilicos de cadena larga y derivados oxa de los mismos y uso como composiciones antivirales. |
| EP1261339A1 (en) * | 2000-02-14 | 2002-12-04 | Pharmacia Corporation | Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds for treating hepatitis virus infections |
| WO2006085141A2 (en) * | 2004-08-13 | 2006-08-17 | Migenix Inc. | Compositions and methods for treating or preventing hepadnaviridae infection |
| US8975280B2 (en) | 2006-05-24 | 2015-03-10 | The Chancellor, Masters And Scholars Of The University Of Oxford | Deoxynojirimycin and D-arabinitol analogs and methods of using |
| JP2010510171A (ja) * | 2006-08-21 | 2010-04-02 | ユナイテッド セラピューティクス コーポレーション | ウイルス感染症の治療のための併用療法 |
| US8097728B2 (en) | 2007-04-30 | 2012-01-17 | Philadelphia Health & Education Corporation | Iminosugar compounds with antiflavirus activity |
| JP2013233113A (ja) * | 2012-05-09 | 2013-11-21 | Osaka Univ | 物理的負荷への耐性が向上した細胞の製造方法 |
| RU2743694C1 (ru) * | 2019-12-04 | 2021-02-24 | Общество с ограниченной ответственностью "29 февраля" | Миглустат N-бутил-1,5-дидезокси-1,5-имино-D-глюцит |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1555654A (en) * | 1977-06-25 | 1979-11-14 | Exxon Research Engineering Co | Agricultural burner apparatus |
| US4849430A (en) * | 1988-03-09 | 1989-07-18 | Monsanto Company | Method of inhibiting virus |
| US4957926A (en) * | 1988-12-22 | 1990-09-18 | Monsanto Company | Method of treating herpesviruses |
| US5030638A (en) * | 1990-02-26 | 1991-07-09 | G. D. Searle & Co. | Method of antiviral enhancement |
-
1994
- 1994-12-23 DE DE69421828T patent/DE69421828T2/de not_active Expired - Lifetime
- 1994-12-23 CN CN94195049A patent/CN1074921C/zh not_active Expired - Lifetime
- 1994-12-23 US US08/676,153 patent/US6037351A/en not_active Expired - Lifetime
- 1994-12-23 JP JP51902495A patent/JP3628021B2/ja not_active Expired - Fee Related
- 1994-12-23 KR KR1019960703780A patent/KR100348657B1/ko not_active Expired - Lifetime
- 1994-12-23 AT AT95905416T patent/ATE186836T1/de active
- 1994-12-23 EP EP95905416A patent/EP0739205B1/en not_active Expired - Lifetime
- 1994-12-23 PT PT95905416T patent/PT739205E/pt unknown
- 1994-12-23 WO PCT/US1994/014548 patent/WO1995019172A1/en not_active Ceased
- 1994-12-23 ES ES95905416T patent/ES2140652T3/es not_active Expired - Lifetime
- 1994-12-23 CA CA002181033A patent/CA2181033C/en not_active Expired - Lifetime
- 1994-12-23 DK DK95905416T patent/DK0739205T3/da active
- 1994-12-23 AU AU14037/95A patent/AU1403795A/en not_active Abandoned
-
2000
- 2000-01-31 GR GR20000400223T patent/GR3032527T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1074921C (zh) | 2001-11-21 |
| JP3628021B2 (ja) | 2005-03-09 |
| EP0739205B1 (en) | 1999-11-24 |
| KR100348657B1 (ko) | 2003-08-02 |
| EP0739205A1 (en) | 1996-10-30 |
| CA2181033A1 (en) | 1995-07-20 |
| ES2140652T3 (es) | 2000-03-01 |
| WO1995019172A1 (en) | 1995-07-20 |
| AU1403795A (en) | 1995-08-01 |
| US6037351A (en) | 2000-03-14 |
| GR3032527T3 (en) | 2000-05-31 |
| CN1149253A (zh) | 1997-05-07 |
| JPH09508111A (ja) | 1997-08-19 |
| CA2181033C (en) | 2007-09-04 |
| DE69421828T2 (de) | 2000-04-20 |
| DE69421828D1 (de) | 1999-12-30 |
| ATE186836T1 (de) | 1999-12-15 |
| PT739205E (pt) | 2000-04-28 |
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