IL86862A - Pharmaceutical compositions for reducing the level of circulating immune complexes in vivo, containing mismatched double-stranded rna - Google Patents

Pharmaceutical compositions for reducing the level of circulating immune complexes in vivo, containing mismatched double-stranded rna

Info

Publication number
IL86862A
IL86862A IL86862A IL8686288A IL86862A IL 86862 A IL86862 A IL 86862A IL 86862 A IL86862 A IL 86862A IL 8686288 A IL8686288 A IL 8686288A IL 86862 A IL86862 A IL 86862A
Authority
IL
Israel
Prior art keywords
stranded rna
vivo
immune complexes
reducing
level
Prior art date
Application number
IL86862A
Other languages
English (en)
Other versions
IL86862A0 (en
Original Assignee
Hem Res Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hem Res Inc filed Critical Hem Res Inc
Publication of IL86862A0 publication Critical patent/IL86862A0/xx
Publication of IL86862A publication Critical patent/IL86862A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
IL86862A 1987-07-17 1988-06-26 Pharmaceutical compositions for reducing the level of circulating immune complexes in vivo, containing mismatched double-stranded rna IL86862A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7461687A 1987-07-17 1987-07-17
US12457787A 1987-11-24 1987-11-24

Publications (2)

Publication Number Publication Date
IL86862A0 IL86862A0 (en) 1988-11-30
IL86862A true IL86862A (en) 1993-05-13

Family

ID=26755855

Family Applications (1)

Application Number Title Priority Date Filing Date
IL86862A IL86862A (en) 1987-07-17 1988-06-26 Pharmaceutical compositions for reducing the level of circulating immune complexes in vivo, containing mismatched double-stranded rna

Country Status (18)

Country Link
EP (1) EP0300680B1 (de)
JP (1) JP2601520B2 (de)
KR (1) KR0131880B1 (de)
CN (1) CN1035050A (de)
AT (1) ATE142500T1 (de)
AU (2) AU1820588A (de)
CA (1) CA1326999C (de)
DE (1) DE3855527T2 (de)
DK (1) DK399288A (de)
ES (1) ES2093607T3 (de)
FI (1) FI883352A7 (de)
HU (1) HUT47432A (de)
IE (1) IE76914B1 (de)
IL (1) IL86862A (de)
NO (1) NO175023C (de)
NZ (1) NZ225310A (de)
OA (1) OA08890A (de)
PT (1) PT87996B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4963532A (en) * 1987-11-25 1990-10-16 Hem Research, Inc. dsRNA-based prevention of viral escape
EP0473576A4 (en) * 1989-05-19 1993-03-10 Hem Research, Inc. Short therapeutic dsrna of defined structure
WO1991005560A1 (en) * 1989-10-11 1991-05-02 Hem Research, Inc. PROTECTION FROM SHOCK SUBSEQUENT TO INJURY BY DOUBLE-STRANDED RNAs
ZA908037B (en) * 1989-10-11 1991-09-25 Hem Res Inc Protection from shock subsequent to injury by double-standed rnas
US5132292A (en) * 1990-05-25 1992-07-21 Hem Research, Inc. Treatment of viral hepatitis
GB9108085D0 (en) * 1991-04-16 1991-06-05 Scras Complexes of polyadenylic acid with polyuridylic acid
AU2268892A (en) * 1991-07-16 1993-02-23 Hem Pharmaceuticals Corp. Modulation and diagnosis of cytokine dysfunctions
FR2768344B1 (fr) * 1997-08-26 2001-02-16 Scras Produit comprenant au moins un arn double brin en association avec au moins un agent anti-viral pour une utilisation therapeutique dans le traitement d'une maladie virale
AR013269A1 (es) * 1997-08-04 2000-12-13 Scras Producto que contiene por lo menos un rna de doble filamento combinado con por lo menos un agente anti-viral, para la utilizacion terapeutica en eltratamiento de una enfermedad viral, en especial de la hepatitis viral
FR2768345B1 (fr) * 1997-09-17 2001-05-04 Scras Produit comprenant au moins un arn double brin en association avec au moins un agent anti-viral pour une utilisation therapeutique dans le traitement d'une maladie virale, notamment d'une hepatite virale
FR2766715B1 (fr) * 1997-08-04 2001-02-16 Scras Produit comprenant au moins de l'arn double brin en association avec au moins un agent anti-viral pour une utilisation therapeutique simultanee, separee ou etalee dans le temps, dans le traitement d'une maladie virale
US6506559B1 (en) 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
AUPP249298A0 (en) 1998-03-20 1998-04-23 Ag-Gene Australia Limited Synthetic genes and genetic constructs comprising same I
CN101818145A (zh) 1998-03-20 2010-09-01 联邦科学和工业研究组织 控制基因表达
CA2361201A1 (en) 1999-01-28 2000-08-03 Medical College Of Georgia Research Institute, Inc. Composition and method for in vivo and in vitro attenuation of gene expression using double stranded rna
US6423885B1 (en) 1999-08-13 2002-07-23 Commonwealth Scientific And Industrial Research Organization (Csiro) Methods for obtaining modified phenotypes in plant cells
CA2369944A1 (en) 2001-01-31 2002-07-31 Nucleonics Inc. Use of post-transcriptional gene silencing for identifying nucleic acid sequences that modulate the function of a cell
EP1838338A2 (de) * 2004-12-29 2007-10-03 Mannkind Corporation Verfahren zum auslösen, erhalten und manipulieren von immunantworten durch gezielte verabreichung von biologischen response-modifikatoren in lymphoiden organen
EP3319587B1 (de) * 2015-11-17 2019-08-21 Bioncotech Therapeutics, S.L Neuartige pharmazeutische zusammensetzung umfassend partikel umfassend einen komplex eines doppelsträngigen polyribonucleotids und eines polyalkylenimins
CN105434341B (zh) * 2015-12-22 2018-07-10 肇庆大华农生物药品有限公司 一种兽用聚腺尿苷酸注射液及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4024222A (en) * 1973-10-30 1977-05-17 The Johns Hopkins University Nucleic acid complexes
US4140761A (en) * 1977-04-11 1979-02-20 The United States Of America As Represented By The Department Of Health, Education & Welfare Modification of hepatitis B virus infection in chronic carriers of hepatitis B surface antigen
EP0113162B1 (de) * 1982-09-16 1989-07-19 Hem Research, Inc. Wucherungshemmende Wirkung von ds-Ribonucleinsäuren auf Tumorzellen
CA1326450C (en) * 1985-08-26 1994-01-25 William A. Carter Modulation of aids virus-related events by double stranded rnas (dsrnas)

Also Published As

Publication number Publication date
FI883352L (fi) 1989-01-18
HUT47432A (en) 1989-03-28
KR890001580A (ko) 1989-03-27
IE76914B1 (en) 1997-11-05
FI883352A0 (fi) 1988-07-14
NO175023C (no) 1994-08-17
NZ225310A (en) 1991-05-28
NO175023B (no) 1994-05-09
FI883352A7 (fi) 1989-01-18
DE3855527T2 (de) 1997-04-03
ES2093607T3 (es) 1997-01-01
EP0300680A3 (de) 1991-06-19
ATE142500T1 (de) 1996-09-15
AU1761195A (en) 1995-06-29
IE881894L (en) 1989-01-17
PT87996A (pt) 1989-06-30
EP0300680B1 (de) 1996-09-11
KR0131880B1 (ko) 1998-04-17
DE3855527D1 (de) 1996-10-17
CN1035050A (zh) 1989-08-30
CA1326999C (en) 1994-02-15
PT87996B (pt) 1995-03-31
JP2601520B2 (ja) 1997-04-16
DK399288D0 (da) 1988-07-15
DK399288A (da) 1989-01-18
NO882853D0 (no) 1988-06-28
AU1820588A (en) 1989-01-19
NO882853L (no) 1989-01-18
IL86862A0 (en) 1988-11-30
JPS6490126A (en) 1989-04-06
OA08890A (en) 1989-10-31
EP0300680A2 (de) 1989-01-25

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Legal Events

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KB Patent renewed
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MM9K Patent not in force due to non-payment of renewal fees