ATE142687T1 - Für (lys46, asp97, asp113> und (lys46, asp113, asp137> thaumatin-i polypeptide kodierende dna - Google Patents

Für (lys46, asp97, asp113> und (lys46, asp113, asp137> thaumatin-i polypeptide kodierende dna

Info

Publication number
ATE142687T1
ATE142687T1 AT90902746T AT90902746T ATE142687T1 AT E142687 T1 ATE142687 T1 AT E142687T1 AT 90902746 T AT90902746 T AT 90902746T AT 90902746 T AT90902746 T AT 90902746T AT E142687 T1 ATE142687 T1 AT E142687T1
Authority
AT
Austria
Prior art keywords
asp113
lys46
thaumatin
asp137
asp97
Prior art date
Application number
AT90902746T
Other languages
English (en)
Inventor
Lindley Calvin Blair
Raju Kanaka Koduri
Jar-How Lee
Joachim Ludwig Weickmann
Original Assignee
Int Genetic Eng
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Int Genetic Eng filed Critical Int Genetic Eng
Application granted granted Critical
Publication of ATE142687T1 publication Critical patent/ATE142687T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C07K14/43—Sweetening agents, e.g. thaumatin, monellin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Botany (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT90902746T 1988-11-08 1989-11-06 Für (lys46, asp97, asp113> und (lys46, asp113, asp137> thaumatin-i polypeptide kodierende dna ATE142687T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26870288A 1988-11-08 1988-11-08
US07/407,416 US5221624A (en) 1988-11-08 1989-09-14 DNA encoding (Lys46, Asp97, Asp113) and (Lys46, Asp.sup.137) thaumatin I polypeptides

Publications (1)

Publication Number Publication Date
ATE142687T1 true ATE142687T1 (de) 1996-09-15

Family

ID=26953274

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90902746T ATE142687T1 (de) 1988-11-08 1989-11-06 Für (lys46, asp97, asp113> und (lys46, asp113, asp137> thaumatin-i polypeptide kodierende dna

Country Status (8)

Country Link
US (1) US5221624A (de)
EP (1) EP0396741B1 (de)
JP (1) JPH03502645A (de)
AT (1) ATE142687T1 (de)
AU (2) AU625879B2 (de)
CA (1) CA2002318C (de)
DE (1) DE68927167T2 (de)
WO (1) WO1990005775A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5234834A (en) * 1987-06-19 1993-08-10 The Regents Of The University Of California Constructs for expression of monellin in plant cells
ES2080689B1 (es) * 1994-04-21 1996-09-01 Urquima Sa Procedimiento de obtencion de un edulcorante natural proteico.
AU6674296A (en) * 1995-06-23 1997-01-22 University Of Hawaii Recombinant sweet protein mabinlin
GB9724307D0 (en) * 1997-11-17 1998-01-14 Zeneca Ltd Improvements relating to protein accumulation
US6274707B1 (en) 1999-04-14 2001-08-14 Wisconsin Alumni Research Foundation Protein sweetener
US6420527B1 (en) * 1999-05-06 2002-07-16 International Flavors & Fragrances Inc. Flavor active modified thaumatin and monellin and methods for their production and use
US9101160B2 (en) 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
US8017168B2 (en) 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith
WO2011105841A2 (ko) * 2010-02-24 2011-09-01 중앙대학교 산학협력단 브라제인 발현용 재조합 발현벡터 및 높은 단맛을 가지는 신규한 브라제인 다중 변이체
KR101083040B1 (ko) 2010-02-24 2011-11-16 중앙대학교 산학협력단 높은 단맛을 가지는 신규한 브라제인 다중 변이체 및 이의 제조방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3177281T2 (de) * 1980-12-12 1992-12-10 Unilever Nv Strukturgene, die fuer die verschiedenen allelischen und reifungsformen von praeprothaumatin und deren mutanten kodieren, diese strukturgene enthaltende klonierungsvektoren und deren expression in mikrobiellen wirtzellen.
IE55817B1 (en) * 1982-05-19 1991-01-30 Gist Brocades Nv Cloning system for kluyveromyces species
US4546082A (en) * 1982-06-17 1985-10-08 Regents Of The Univ. Of California E. coli/Saccharomyces cerevisiae plasmid cloning vector containing the alpha-factor gene for secretion and processing of hybrid proteins
AU577334B2 (en) * 1983-10-11 1988-09-22 International Genetic Engineering, Inc. Synthetic thaumatin genes
US4766205A (en) * 1985-11-13 1988-08-23 Beatrice Companies, Inc. Method for isolation of recombinant polypeptides in biologically active forms
ATE85812T1 (de) * 1985-11-13 1993-03-15 Xoma Corp Verkuerzter phosphoglycerat-kinase-promotor.
CA1310923C (en) * 1985-11-13 1992-12-01 Joachim Ludwig Weickmann Dna encoding [asp --] and [lys -, asp --] thaumatin i
IL82935A0 (en) * 1986-08-12 1987-12-20 Phillips Petroleum Co Secretion of heterologous proteins from yeast

Also Published As

Publication number Publication date
DE68927167T2 (de) 1997-04-03
DE68927167D1 (de) 1996-10-17
EP0396741B1 (de) 1996-09-11
AU625879B2 (en) 1992-07-16
AU2707092A (en) 1992-12-17
CA2002318C (en) 2000-05-23
EP0396741A4 (en) 1992-03-11
US5221624A (en) 1993-06-22
WO1990005775A1 (en) 1990-05-31
CA2002318A1 (en) 1990-05-08
AU5045090A (en) 1990-06-12
JPH03502645A (ja) 1991-06-20
AU651501B2 (en) 1994-07-21
EP0396741A1 (de) 1990-11-14

Similar Documents

Publication Publication Date Title
ATE112135T1 (de) Überexpression von phytochrom in transgenen pflanzen.
ATE142687T1 (de) Für (lys46, asp97, asp113> und (lys46, asp113, asp137> thaumatin-i polypeptide kodierende dna
MC2211A1 (fr) Production de polypeptides recombinants par une espece bovine et procedes transgeniques
ATE377360T1 (de) Neuartige phytase
ATE386126T1 (de) Verbesserte expressionsvektoren
NO863806D0 (no) Arab promotorer og fremgangsmaate for fremstilling av polypeptider inkludert cecropiner, ved mikrobiologiske teknikker.
ATE91722T1 (de) Pferde-gamma-interferon.
EP0205475A4 (de) Rekombinantverfahren zur herstellung von serinproteaseinhibitoren, sowie dns-sequenzen dazu.
DK295188A (da) Fibronectinbindende protein og fremgangsmaade til fremstilling heraf
DK1908772T3 (da) Polypeptider og polynucleinsyrer af phorphorymonas gingivalis
JPS6413997A (en) Dna molecule useful for protection of plant
ATE71148T1 (de) Dns-kodierendes (asp 113> und (lys 46, asp 113> thaumatin-i.
ATE286972T1 (de) Für phosphoenolpyruvatcarboxykinase kodierende dna, sie enthaltender rekombinanter vektor und transgene pflanze
AU648029B2 (en) Streptokinase proteins, corresponding genes, corresponding plasmid recombinants, corresponding transformants and processes for preparing same
SE8801723D0 (sv) Fibronectin binding protein as well as its preparation
EP1010761A4 (de) Gen
DE69737321D1 (de) Polypeptide der menschlichen hyaluronan-synthase und dafür kodierende dns
DK27097A (da) Minactivin og fremgangsmåde til fremstilling deraf
EP1295943A4 (de) Polypeptide mit aktivität der stimulierung von neutrophilen
EP0367641A3 (en) Lymphokines, dna sequences encoding these lymphokines and pharmaceutical compositions containing these lymphokines
ATE107694T1 (de) Für a.nidulans-isopenicillin-n-synthetase codierende dns, deren verwendung und dafür codierende vektoren.
PH31199A (en) Coding, promoter and regulator sequences of irf-1.
IT1251680B (it) Clonaggio e sequenziamento dell'operone srfa di bacillus subtilis che codifica il complesso multienzimatico surfattina sintetasi
NO914130L (no) Forbedret ekspresjon av polypeptider
DK56995A (da) Rekombinante lymphotoxin-varianter

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties