ATE142697T1 - Impfstoff gegen bordetella pertussis - Google Patents

Impfstoff gegen bordetella pertussis

Info

Publication number
ATE142697T1
ATE142697T1 AT89870113T AT89870113T ATE142697T1 AT E142697 T1 ATE142697 T1 AT E142697T1 AT 89870113 T AT89870113 T AT 89870113T AT 89870113 T AT89870113 T AT 89870113T AT E142697 T1 ATE142697 T1 AT E142697T1
Authority
AT
Austria
Prior art keywords
vaccine against
bordetella pertussis
against bordetella
pertussis
vaccine
Prior art date
Application number
AT89870113T
Other languages
English (en)
Inventor
Carine Capiau
Camille Locht
Original Assignee
Smithkline Beecham Biolog
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Biolog filed Critical Smithkline Beecham Biolog
Application granted granted Critical
Publication of ATE142697T1 publication Critical patent/ATE142697T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT89870113T 1988-07-22 1989-07-20 Impfstoff gegen bordetella pertussis ATE142697T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US22299188A 1988-07-22 1988-07-22

Publications (1)

Publication Number Publication Date
ATE142697T1 true ATE142697T1 (de) 1996-09-15

Family

ID=22834543

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89870113T ATE142697T1 (de) 1988-07-22 1989-07-20 Impfstoff gegen bordetella pertussis

Country Status (16)

Country Link
EP (1) EP0352250B1 (de)
JP (1) JP2798986B2 (de)
KR (1) KR900001852A (de)
AP (1) AP8900132A0 (de)
AT (1) ATE142697T1 (de)
AU (1) AU3827089A (de)
DE (1) DE68927144T2 (de)
DK (1) DK355789A (de)
FI (1) FI893512L (de)
HU (1) HUT52701A (de)
IL (1) IL90994A0 (de)
NO (1) NO892997L (de)
NZ (1) NZ229954A (de)
OA (1) OA10038A (de)
PT (1) PT91248A (de)
ZA (1) ZA895573B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE106747T1 (de) * 1987-06-24 1994-06-15 Teijin Ltd Bordetella pertussis-varianten.
GB8727489D0 (en) * 1987-11-24 1987-12-23 Connaught Lab Detoxification of pertussis toxin
ES2078258T3 (es) * 1989-04-28 1995-12-16 Sclavo Spa Mutantes de toxina pertussica, cepas de bordetella capaces de producir tales mutantes y su uso en el desarrollo de vacunas antipertussicas.
AU644828B2 (en) * 1989-11-29 1993-12-23 Smithkline Beecham Biologicals (Sa) Novel vaccine
US5786189A (en) * 1989-11-29 1998-07-28 Smithkline Beecham Biologicals (S.A.) Vaccine
IT1248735B (it) * 1990-06-21 1995-01-26 Sclavo Spa Vaccini acellulari contro la pertosse
DK0725653T3 (da) * 1993-10-05 2004-10-11 Celltech Pharmaceuticals Ltd Vaccinepræparater
US20030072774A1 (en) * 1994-06-10 2003-04-17 Diane M. Gajewczyk Proteinaceous adjuvants

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340373C (en) * 1986-01-28 1999-02-02 Rino Rappuoli Cloning and sequencing of the dna fragment which codes for the five subunits of the pertussis toxin, a hybrid plasmid containing the dna fragment and micro-organisms transformed by the hybrid plasmid and capable of expressing all or some of the subunits of the pertussis toxin
US4762710A (en) * 1986-06-16 1988-08-09 The United States Of America As Represented By The Department Of Health And Human Services Novel method of preparing toxoid by oxidation and metal ions
IT1223334B (it) * 1987-11-02 1990-09-19 Sclavo Spa Polipeptidi immunologicamente attivi con una tossicita' alterata utili per la preparazione di un vaccino antipertosse
GB8727489D0 (en) * 1987-11-24 1987-12-23 Connaught Lab Detoxification of pertussis toxin
ES2078258T3 (es) * 1989-04-28 1995-12-16 Sclavo Spa Mutantes de toxina pertussica, cepas de bordetella capaces de producir tales mutantes y su uso en el desarrollo de vacunas antipertussicas.

Also Published As

Publication number Publication date
KR900001852A (ko) 1990-02-27
FI893512A0 (fi) 1989-07-20
JPH0284183A (ja) 1990-03-26
IL90994A0 (en) 1990-02-09
DE68927144D1 (de) 1996-10-17
EP0352250B1 (de) 1996-09-11
NO892997D0 (no) 1989-07-21
DK355789D0 (da) 1989-07-18
FI893512A7 (fi) 1990-01-23
HK1004568A1 (en) 1998-11-27
JP2798986B2 (ja) 1998-09-17
FI893512L (fi) 1990-01-23
NZ229954A (en) 1992-09-25
DK355789A (da) 1990-01-23
PT91248A (pt) 1990-02-08
NO892997L (no) 1990-01-23
AP8900132A0 (en) 1991-01-14
DE68927144T2 (de) 1997-03-20
EP0352250A2 (de) 1990-01-24
ZA895573B (en) 1990-07-25
EP0352250A3 (de) 1990-11-14
HUT52701A (en) 1990-08-28
AU3827089A (en) 1990-01-25
OA10038A (en) 1996-10-14

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties