ATE144701T1 - Verwendung einer kombination aus gelbindender polysacchariden und fein verteilten arzneimittelträgern in ophtalmischen topischen zusammensetzungen - Google Patents

Verwendung einer kombination aus gelbindender polysacchariden und fein verteilten arzneimittelträgern in ophtalmischen topischen zusammensetzungen

Info

Publication number
ATE144701T1
ATE144701T1 AT92105334T AT92105334T ATE144701T1 AT E144701 T1 ATE144701 T1 AT E144701T1 AT 92105334 T AT92105334 T AT 92105334T AT 92105334 T AT92105334 T AT 92105334T AT E144701 T1 ATE144701 T1 AT E144701T1
Authority
AT
Austria
Prior art keywords
ophtalmic
yellow
combination
topical compositions
drug carriers
Prior art date
Application number
AT92105334T
Other languages
English (en)
Inventor
Paul Joseph Tracy Missel
Rajni Jani
John C Lang
Original Assignee
Alcon Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Lab Inc filed Critical Alcon Lab Inc
Application granted granted Critical
Publication of ATE144701T1 publication Critical patent/ATE144701T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A61K47/585—Ion exchange resins, e.g. polystyrene sulfonic acid resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Virology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT92105334T 1991-03-27 1992-03-27 Verwendung einer kombination aus gelbindender polysacchariden und fein verteilten arzneimittelträgern in ophtalmischen topischen zusammensetzungen ATE144701T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US67614691A 1991-03-27 1991-03-27

Publications (1)

Publication Number Publication Date
ATE144701T1 true ATE144701T1 (de) 1996-11-15

Family

ID=24713413

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92105334T ATE144701T1 (de) 1991-03-27 1992-03-27 Verwendung einer kombination aus gelbindender polysacchariden und fein verteilten arzneimittelträgern in ophtalmischen topischen zusammensetzungen

Country Status (9)

Country Link
EP (1) EP0507224B1 (de)
JP (1) JP2536806B2 (de)
AT (1) ATE144701T1 (de)
AU (1) AU654175B2 (de)
CA (1) CA2064160C (de)
DE (1) DE69214863T2 (de)
DK (1) DK0507224T3 (de)
ES (1) ES2095975T3 (de)
GR (1) GR3022385T3 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5932572A (en) * 1992-02-21 1999-08-03 Alcon Laboratories, Inc. Topical anti-glaucoma compositions
WO1993016701A2 (en) * 1992-02-21 1993-09-02 Alcon Laboratories, Inc. Topical antiglaucoma compositions comprising carbonic anhydrase inhibitors and beta-blockers
CA2131101A1 (en) * 1992-05-13 1993-11-25 Louis Desantis Jr. Topical ophthalmic compositions comprising a combination of calcium antagonists with known antiglaucoma agents
US5422116A (en) * 1994-02-18 1995-06-06 Ciba-Geigy Corporation Liquid ophthalmic sustained release delivery system
IL114193A (en) * 1994-06-20 2000-02-29 Teva Pharma Ophthalmic pharmaceutical compositions based on sodium alginate
AU705718B2 (en) * 1995-05-24 1999-05-27 Alcon Laboratories, Inc. Antibacterial compositions
FR2754712B1 (fr) * 1996-10-17 1999-09-03 Merck Sharp Dohme Chibret Lab Compositions ophtalmiques
JP2002506461A (ja) * 1997-06-26 2002-02-26 メルク エンド カンパニー インコーポレーテッド 網膜及び視神経の健康の最適化方法
BR0112787B1 (pt) * 2000-07-28 2013-03-05 composiÇço de soluÇço topicamente administrÁvel.
WO2003013612A1 (fr) * 2001-08-10 2003-02-20 Toray Industries, Inc. Compositions contenant du polysaccharide et leur utilisation
EP1474109B1 (de) * 2001-12-21 2010-08-25 Alcon, Inc. Verwendung von synthetischen anorganischen nanoteilchen als träger für augenmedikamente
EP1471925A2 (de) * 2001-12-21 2004-11-03 Alcon, Inc. Anorganische nanopartikel zur modifizierung der viskosität und physikalischer eigenschaften von ophthalmischen und ohrenheilkundigen zusammensetzungen
JP4725699B2 (ja) * 2002-04-08 2011-07-13 ライオン株式会社 眼科用組成物及び眼科用組成物配合用防腐剤
US8580851B2 (en) 2002-08-21 2013-11-12 Sucampo Ag Ophthalmic solution
ES2431640T3 (es) * 2003-08-21 2013-11-27 Sucampo Ag Composición oftálmica que comprende éster isopropílico de unoprostona y un agente de viscosidad
PT3500255T (pt) 2016-08-19 2023-01-10 Orasis Pharmaceuticals Ltd Composições farmacêuticas oftálmicas e utilizações relacionadas com estas
PL3681500T3 (pl) 2018-04-24 2022-08-01 Allergan, Inc. Zastosowanie chlorowodorku pilokarpiny w leczeniu starczowzroczności
GB202008919D0 (en) * 2020-06-11 2020-07-29 Univ Birmingham Polysaccharide conpositions and therapeutic gels
IT202200021852A1 (it) 2022-10-21 2024-04-21 Montefarmaco Otc S P A Composizione liquida oftalmica viscosa comprendente gomme ed estratti naturali
WO2026042047A1 (en) * 2024-08-23 2026-02-26 Johnson & Johnson Vision Care, Inc. Compositions and articles comprising reversible complexes of crosslinked carrageenan

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4136173A (en) * 1977-01-31 1979-01-23 American Home Products Corp. Mixed xanthan gum and locust beam gum therapeutic compositions
US4136178A (en) * 1977-01-31 1979-01-23 American Home Products Corp. Locust bean gum therapeutic compositions
US4136177A (en) * 1977-01-31 1979-01-23 American Home Products Corp. Xanthan gum therapeutic compositions
US4911920A (en) * 1986-07-30 1990-03-27 Alcon Laboratories, Inc. Sustained release, comfort formulation for glaucoma therapy
FR2653021A1 (fr) * 1989-10-17 1991-04-19 Merck Sharp & Dohme Composition ophtalmique aqueuse liquide a transition de phase liquide-gel.
AU651655B2 (en) * 1991-01-15 1994-07-28 Alcon Laboratories, Inc. Use of carrageenans in topical ophthalmic compositions

Also Published As

Publication number Publication date
GR3022385T3 (en) 1997-04-30
DK0507224T3 (da) 1997-04-07
ES2095975T3 (es) 1997-03-01
JPH0710776A (ja) 1995-01-13
DE69214863D1 (de) 1996-12-05
AU654175B2 (en) 1994-10-27
AU1386392A (en) 1992-10-01
EP0507224A3 (de) 1992-10-28
JP2536806B2 (ja) 1996-09-25
EP0507224A2 (de) 1992-10-07
EP0507224B1 (de) 1996-10-30
CA2064160C (en) 1998-08-11
CA2064160A1 (en) 1992-09-28
DE69214863T2 (de) 1997-04-10

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee