ATE145406T1 - Gamma-retinoinsäure-rezeptor - Google Patents

Gamma-retinoinsäure-rezeptor

Info

Publication number
ATE145406T1
ATE145406T1 AT90911356T AT90911356T ATE145406T1 AT E145406 T1 ATE145406 T1 AT E145406T1 AT 90911356 T AT90911356 T AT 90911356T AT 90911356 T AT90911356 T AT 90911356T AT E145406 T1 ATE145406 T1 AT E145406T1
Authority
AT
Austria
Prior art keywords
retinoic acid
acid receptor
gamma retinoic
receptor
disclosed
Prior art date
Application number
AT90911356T
Other languages
English (en)
Inventor
Fumimaro Takaku
Michio Imawari
Takashi Ishikawa
Ronald Mark Evans
Kazuhiko Umesono
Original Assignee
Salk Inst For Biological Studi
Sloan Kettering Inst Cancer
Fumimaro Takaku
Michio Imawari
Takashi Ishikawa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Salk Inst For Biological Studi, Sloan Kettering Inst Cancer, Fumimaro Takaku, Michio Imawari, Takashi Ishikawa filed Critical Salk Inst For Biological Studi
Application granted granted Critical
Publication of ATE145406T1 publication Critical patent/ATE145406T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70567—Nuclear receptors, e.g. retinoic acid receptor [RAR], RXR, nuclear orphan receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/721—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/71—Fusion polypeptide containing domain for protein-protein interaction containing domain for transcriptional activaation, e.g. VP16
    • C07K2319/715—Fusion polypeptide containing domain for protein-protein interaction containing domain for transcriptional activaation, e.g. VP16 containing a domain for ligand dependent transcriptional activation, e.g. containing a steroid receptor domain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/80—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/826—Viruses
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/843—Digestive system
    • Y10S530/846—Liver

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Physics & Mathematics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT90911356T 1989-06-22 1990-06-22 Gamma-retinoinsäure-rezeptor ATE145406T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/370,407 US5260432A (en) 1989-06-22 1989-06-22 Human gamma retinoic acid receptor DNA

Publications (1)

Publication Number Publication Date
ATE145406T1 true ATE145406T1 (de) 1996-12-15

Family

ID=23459521

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90911356T ATE145406T1 (de) 1989-06-22 1990-06-22 Gamma-retinoinsäure-rezeptor

Country Status (10)

Country Link
US (4) US5260432A (de)
EP (1) EP0479916B1 (de)
JP (1) JP3240056B2 (de)
KR (1) KR0159106B1 (de)
AT (1) ATE145406T1 (de)
AU (1) AU640940B2 (de)
CA (1) CA2066692A1 (de)
DE (1) DE69029197T2 (de)
ES (1) ES2094157T3 (de)
WO (1) WO1990015815A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5571692A (en) * 1987-12-02 1996-11-05 The Salk Institute For Biological Studies Retinoic acid receptor α, vectors and cells comprising the same DNA encoding
US5260432A (en) * 1989-06-22 1993-11-09 Sloan-Kettering Institute For Cancer Research Human gamma retinoic acid receptor DNA
EP0411323A3 (en) * 1989-06-30 1991-08-21 Institut National De La Sante Et De La Recherche Medicale (Inserm) Human and mouse retinoic acid receptors and genes encoding for them
JPH05504479A (ja) * 1990-02-09 1993-07-15 ザ　ソーク　インスティテュート　フォア　バイオロジカル　スタディーズ レチノイドレセプター組成物および方法
US5641652A (en) * 1990-03-22 1997-06-24 The Salk Institute For Biological Studies Insect retinoid-like receptor compositions and methods
US5861274A (en) * 1990-03-22 1999-01-19 The Salk Institute For Biological Studies Nucleic acids encoding peroxisome proliferator-activated receptor
US5922596A (en) * 1990-12-10 1999-07-13 Bristol-Myers Squibb Co. Promoter of the retinoic acid receptor gene for directing gene expression
US6989242B1 (en) 1992-02-26 2006-01-24 The General Hospital Coporation Car receptors and related molecules and methods
US5756448A (en) * 1992-02-26 1998-05-26 The General Hospital Corporation Constitute activator of retinoid (CAR) receptor polypeptides
PL310327A1 (en) * 1993-02-12 1995-12-11 Univ Leland Stanford Junior Adjustable transcription of target genes and other biological processes
US6891021B2 (en) 1993-02-12 2005-05-10 Board Of Trustees Of The Leland Stanford Junior University Regulated apoptosis
JPH08504104A (ja) * 1993-05-18 1996-05-07 アンスティテュー・ナシオナル・ドゥ・ラ・サンテ・エ・ドゥ・ラ・ルシェルシュ・メディカル レチノイン酸レセプター蛋白をコード化する遺伝子における改変を含む遺伝子工学的マウス
US6031149A (en) 1993-05-18 2000-02-29 Institut National De La Sante Et De La Recherche Medicale Genetically engineered mice containing alterations in the genes encoding retinoic acid receptor proteins
WO1996000242A1 (en) * 1994-06-24 1996-01-04 Human Genome Sciences, Inc. Retinoic acid receptor epsilon
AU2952695A (en) * 1994-07-01 1996-01-25 Salk Institute For Biological Studies, The Mammalian peroxisome proliferator-activated receptors and uses thereof
US6489441B1 (en) 1995-09-01 2002-12-03 The Salk Institute For Biological Studies Transcriptional co-repressor that interacts with nuclear hormone receptors
US5939264A (en) * 1996-07-19 1999-08-17 Iowa State University Research Foundation, Inc. Genes and genetic markers for improved reproductive traits in animals
US6184256B1 (en) 1997-04-24 2001-02-06 INSTITUT NATIONAL DE LA SANTé DE LA RECHERCHE MéDICALE Methods and compositions for use in modulating expression of matrix metalloproteinase genes
AUPP012097A0 (en) 1997-10-30 1997-11-27 Commonwealth Scientific And Industrial Research Organisation Assessing lipid metabolism
US6521814B1 (en) 1997-12-22 2003-02-18 Institut National De La Santa Et De La Recherche Medicale Use of ligands for treatment of diseases responsive to retinoids
US6665594B1 (en) * 2001-12-13 2003-12-16 The United States Of America As Represented By The Secretary Of The Navy Plug and play modular mission payloads
AU2002318168B2 (en) 2002-02-25 2007-12-13 Vaxiion Therapeutics, Llc Minicell compositions and methods
WO2008114672A1 (ja) * 2007-03-15 2008-09-25 Reverse Proteomics Research Institute Co., Ltd. がんに特異的なバイオマーカー
US10119150B2 (en) 2012-05-13 2018-11-06 Allele Biotechnology & Pharmaceuticals, Inc. Feeder-free Derivation of human-induced pluripotent stem cells with synthetic messenger RNA
US10155929B2 (en) 2012-05-13 2018-12-18 Allele Biotechnology & Pharmaceuticals, Inc. Feeder-free derivation of human-induced pluripotent stem cells with synthetic messenger RNA
CN110241087B (zh) * 2012-05-13 2023-02-03 美国绿阳生物技术及医药公司 使用合成的信使rna无饲养细胞地衍生人类诱导性多能干细胞

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5171671A (en) * 1987-12-02 1992-12-15 The Salk Institute For Biological Studies Retinoic acid receptor composition
US4981784A (en) * 1987-12-02 1991-01-01 The Salk Institute For Biological Studies Retinoic acid receptor method
CA1320161C (en) * 1987-12-16 1993-07-13 Hugues Blaudin De The Steroid/thyroid hormone receptor-related gene, which is inappropriately expressed in human heptocellular carcinoma, and which is a retinoic acid receptor
US5260432A (en) * 1989-06-22 1993-11-09 Sloan-Kettering Institute For Cancer Research Human gamma retinoic acid receptor DNA
US5091518A (en) * 1989-11-16 1992-02-25 The Salk Institute For Biological Studies Beta retinoic acid response elements compositions and assays

Also Published As

Publication number Publication date
US6284870B1 (en) 2001-09-04
EP0479916A1 (de) 1992-04-15
US5260432A (en) 1993-11-09
AU640940B2 (en) 1993-09-09
US7033828B2 (en) 2006-04-25
US20020077457A1 (en) 2002-06-20
EP0479916A4 (en) 1992-10-07
CA2066692A1 (en) 1990-12-23
DE69029197D1 (de) 1997-01-02
KR0159106B1 (ko) 1998-11-16
WO1990015815A1 (en) 1990-12-27
AU6051990A (en) 1991-01-08
JP3240056B2 (ja) 2001-12-17
US5530094A (en) 1996-06-25
DE69029197T2 (de) 1997-04-10
JPH05501349A (ja) 1993-03-18
US20040171800A9 (en) 2004-09-02
ES2094157T3 (es) 1997-01-16
EP0479916B1 (de) 1996-11-20

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