ATE146184T1 - Neue kardioaktive zyklopentaperhydrophenanthrene- 17-beta-(hydroxy oder alkoxy)-17-alpha-(aryl oder heterozyklyl)-3-beta derivate, ein verfahren zu ihrer herstellung und pharmazeutische präparate davon - Google Patents

Neue kardioaktive zyklopentaperhydrophenanthrene- 17-beta-(hydroxy oder alkoxy)-17-alpha-(aryl oder heterozyklyl)-3-beta derivate, ein verfahren zu ihrer herstellung und pharmazeutische präparate davon

Info

Publication number: ATE146184T1
Authority: AT; Austria
Prior art keywords: beta; heterocyclyl; alkoxy; aryl; alpha
Prior art date: 1992-09-29

Application number

AT93115247T

Other languages

English (en)

Inventor

Mauro Gobbini

Mara Ferrandi

Marco Frigerio

Piero Melloni

Marco Torri

Loredana Valentino

Original Assignee

Sigma Tau Ind Farmaceuti

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-09-29

Filing date

1993-09-22

Publication date

1996-12-15

1993-09-22 Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti

1996-12-15 Application granted granted Critical

1996-12-15 Publication of ATE146184T1 publication Critical patent/ATE146184T1/de

Links

238000000034 method Methods 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title 1
239000000825 pharmaceutical preparation Substances 0.000 title 1
206010019280 Heart failures Diseases 0.000 abstract 1
206010020772 Hypertension Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/003—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring the S atom directly linked to a ring carbon atom of the cyclopenta(a)hydrophenanthrene skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J33/002—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0088—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing unsubstituted amino radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT93115247T 1992-09-29 1993-09-22 Neue kardioaktive zyklopentaperhydrophenanthrene- 17-beta-(hydroxy oder alkoxy)-17-alpha-(aryl oder heterozyklyl)-3-beta derivate, ein verfahren zu ihrer herstellung und pharmazeutische präparate davon ATE146184T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4232656A DE4232656C2 (de)	1992-09-29	1992-09-29	Cyclopentanperhydrophenanthren-17-furyl-3ß-derivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutischen Zusammensetzungen

Publications (1)

Publication Number	Publication Date
ATE146184T1 true ATE146184T1 (de)	1996-12-15

Family

ID=6469153

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT93115247T ATE146184T1 (de)	1992-09-29	1993-09-22	Neue kardioaktive zyklopentaperhydrophenanthrene- 17-beta-(hydroxy oder alkoxy)-17-alpha-(aryl oder heterozyklyl)-3-beta derivate, ein verfahren zu ihrer herstellung und pharmazeutische präparate davon

Country Status (9)

Country	Link
US (1)	US5521167A (de)
EP (1)	EP0590489B1 (de)
JP (1)	JPH06211893A (de)
AT (1)	ATE146184T1 (de)
DE (2)	DE4232656C2 (de)
DK (1)	DK0590489T3 (de)
ES (1)	ES2095542T3 (de)
GR (1)	GR3021998T3 (de)
HK (1)	HK1005879A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19633349A1 (de) *	1996-08-19	1998-02-26	Sigma Tau Ind Farmaceuti	Neue 6-Hydroxy- und 6-Oxo-androstan-Derivate, die auf das kardiovaskuläre System wirken und pharmazeutische Zusammensetzungen, die diese enthalten
US6093389A (en) *	1997-12-01	2000-07-25	American Cyanamid Company	Methods and compositions for attracting and controlling termites
US8084446B2 (en)	2005-04-26	2011-12-27	Eric Marchewitz	Use of DHEA derivatives for enhancing physical performance

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2938030A (en) *	1956-10-03	1960-05-24	Ciba Pharm Prod Inc	New steroids substituted by a heterocyclic nitrogen-containing ring in 17-position
DE1227015B (de) *	1963-01-23	1966-10-20	Bayer Ag	Verfahren zur Herstellung von 3beta-Hydroxy-(bzw.-Acyloxy)-steroid-20-amidylhydrazonen der Pregnanreihe
US3436390A (en) *	1966-05-24	1969-04-01	American Home Prod	4,4-dihydroxy-2-butenoic acid lactones
US3398138A (en) *	1966-05-24	1968-08-20	American Home Prod	Novel cardenolides and derivatives
FR2414514A1 (fr) *	1978-01-11	1979-08-10	Roussel Uclaf	Nouveaux derives steroides 17aaryle ou aheteroaryle, leur procede de preparation et leur application comme medicament
IE53463B1 (en) *	1981-06-15	1988-11-23	Akzo Nv	Mono-and bisquaternary ammonium derivatives of 2 beta,16 beta-d-amino-5 alpha-androstane derivatives and pharmaceutical preparations containing same
US5506354A (en) *	1985-09-12	1996-04-09	The Upjohn Company	Imidazolylpiperazinyl steroids
GB8916636D0 (en) *	1989-07-20	1989-09-06	Erba Carlo Spa	Steroid ethers
DE4221636C1 (de) *	1992-07-01	1994-03-31	Sigma Tau Ind Farmaceuti	Cyclopentanperhydrophenanthren-17beta-(3-furyl)-3-Derivate
DE4227605C2 (de) *	1992-08-20	1995-02-16	Sigma Tau Ind Farmaceuti	17-Hydroxyiminomethyl-14beta-hydroxy-5ß-androstan-Derivate, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen, die dieselben enthalten
US5252630A (en) *	1992-10-15	1993-10-12	Duke University	Antifouling coating and method for using same

1992
- 1992-09-29 DE DE4232656A patent/DE4232656C2/de not_active Expired - Fee Related
1993
- 1993-09-22 DE DE69306513T patent/DE69306513T2/de not_active Expired - Fee Related
- 1993-09-22 AT AT93115247T patent/ATE146184T1/de active
- 1993-09-22 ES ES93115247T patent/ES2095542T3/es not_active Expired - Lifetime
- 1993-09-22 EP EP93115247A patent/EP0590489B1/de not_active Expired - Lifetime
- 1993-09-22 DK DK93115247.4T patent/DK0590489T3/da active
- 1993-09-29 US US08/128,128 patent/US5521167A/en not_active Expired - Fee Related
- 1993-09-29 JP JP5243360A patent/JPH06211893A/ja not_active Withdrawn
1996
- 1996-12-12 GR GR960402371T patent/GR3021998T3/el unknown
1998
- 1998-06-05 HK HK98104948A patent/HK1005879A1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE69306513D1 (de)	1997-01-23
EP0590489B1 (de)	1996-12-11
DE69306513T2 (de)	1997-05-15
EP0590489A3 (en)	1994-06-29
US5521167A (en)	1996-05-28
GR3021998T3 (en)	1997-03-31
DE4232656A1 (de)	1994-03-31
ES2095542T3 (es)	1997-02-16
HK1005879A1 (en)	1999-01-29
DK0590489T3 (da)	1996-12-30
JPH06211893A (ja)	1994-08-02
EP0590489A2 (de)	1994-04-06
DE4232656C2 (de)	1995-01-12

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