ATE147750T1 - Phosphotriester-typ biologisch-aktiver verbindungen - Google Patents

Phosphotriester-typ biologisch-aktiver verbindungen

Info

Publication number
ATE147750T1
ATE147750T1 AT93910147T AT93910147T ATE147750T1 AT E147750 T1 ATE147750 T1 AT E147750T1 AT 93910147 T AT93910147 T AT 93910147T AT 93910147 T AT93910147 T AT 93910147T AT E147750 T1 ATE147750 T1 AT E147750T1
Authority
AT
Austria
Prior art keywords
biologically active
active compounds
radical
phosphotriester
type
Prior art date
Application number
AT93910147T
Other languages
English (en)
Inventor
Gilles Residence Parc Gosselin
Jean-Louis Lab De Chimi Imbach
Bataillon
Original Assignee
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9206383A external-priority patent/FR2691463A1/fr
Application filed by Centre Nat Rech Scient filed Critical Centre Nat Rech Scient
Application granted granted Critical
Publication of ATE147750T1 publication Critical patent/ATE147750T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT93910147T 1992-05-25 1993-05-24 Phosphotriester-typ biologisch-aktiver verbindungen ATE147750T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9206383A FR2691463A1 (fr) 1992-05-25 1992-05-25 Dérivés nucléotidiques, leur préparation et leur application en thérapeutique.
FR9304117A FR2692265B1 (fr) 1992-05-25 1993-04-07 Composes biologiquement actifs de type phosphotriesters.

Publications (1)

Publication Number Publication Date
ATE147750T1 true ATE147750T1 (de) 1997-02-15

Family

ID=26229484

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93910147T ATE147750T1 (de) 1992-05-25 1993-05-24 Phosphotriester-typ biologisch-aktiver verbindungen

Country Status (11)

Country Link
US (2) US6399589B1 (de)
EP (1) EP0642528B1 (de)
JP (1) JP3628324B2 (de)
AT (1) ATE147750T1 (de)
CA (1) CA2136622C (de)
DE (1) DE69307506T2 (de)
DK (1) DK0642528T3 (de)
ES (1) ES2099436T3 (de)
FR (1) FR2692265B1 (de)
GR (1) GR3023130T3 (de)
WO (1) WO1993024510A1 (de)

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EP0642528B1 (de) 1997-01-15
FR2692265B1 (fr) 1996-11-08
GR3023130T3 (en) 1997-07-30
FR2692265A1 (fr) 1993-12-17
DK0642528T3 (da) 1997-07-21
EP0642528A1 (de) 1995-03-15
DE69307506T2 (de) 1997-07-03
ES2099436T3 (es) 1997-05-16
US20020037873A1 (en) 2002-03-28
JP3628324B2 (ja) 2005-03-09
WO1993024510A1 (fr) 1993-12-09
CA2136622A1 (fr) 1993-12-09
US6555676B2 (en) 2003-04-29
DE69307506D1 (de) 1997-02-27
US6399589B1 (en) 2002-06-04
JPH07507068A (ja) 1995-08-03
CA2136622C (fr) 2006-01-03

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