ATE147755T1 - Dipeptidderivate und diese als aktive bestandteile enthaltendes prophylaktisches oder therapeutisches mittel gegen knochenkrankheiten - Google Patents

Dipeptidderivate und diese als aktive bestandteile enthaltendes prophylaktisches oder therapeutisches mittel gegen knochenkrankheiten

Info

Publication number
ATE147755T1
ATE147755T1 AT93109551T AT93109551T ATE147755T1 AT E147755 T1 ATE147755 T1 AT E147755T1 AT 93109551 T AT93109551 T AT 93109551T AT 93109551 T AT93109551 T AT 93109551T AT E147755 T1 ATE147755 T1 AT E147755T1
Authority
AT
Austria
Prior art keywords
prophylactic
therapeutic agent
active ingredients
bone diseases
agent against
Prior art date
Application number
AT93109551T
Other languages
English (en)
Inventor
Naoki Higuchi
Masayuki Saitoh
Shinjiro Niwata
Yoshinobu Kiso
Yasuhiro Hayashi
Original Assignee
Suntory Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suntory Ltd filed Critical Suntory Ltd
Application granted granted Critical
Publication of ATE147755T1 publication Critical patent/ATE147755T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT93109551T 1992-06-15 1993-06-15 Dipeptidderivate und diese als aktive bestandteile enthaltendes prophylaktisches oder therapeutisches mittel gegen knochenkrankheiten ATE147755T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4155115A JPH05345754A (ja) 1992-06-15 1992-06-15 ジペプチド誘導体およびそれを有効成分とする骨疾患の予防または治療剤

Publications (1)

Publication Number Publication Date
ATE147755T1 true ATE147755T1 (de) 1997-02-15

Family

ID=15598916

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93109551T ATE147755T1 (de) 1992-06-15 1993-06-15 Dipeptidderivate und diese als aktive bestandteile enthaltendes prophylaktisches oder therapeutisches mittel gegen knochenkrankheiten

Country Status (5)

Country Link
US (1) US5399743A (de)
EP (1) EP0578978B1 (de)
JP (1) JPH05345754A (de)
AT (1) ATE147755T1 (de)
DE (1) DE69307414T2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5863902A (en) * 1995-01-06 1999-01-26 Sibia Neurosciences, Inc. Methods of treating neurodegenerative disorders using protease inhibitors
US5804560A (en) * 1995-01-06 1998-09-08 Sibia Neurosciences, Inc. Peptide and peptide analog protease inhibitors
WO2000064845A1 (en) * 1999-04-22 2000-11-02 Sankyo Company, Limited Resin-bearing ketoamides and process for the preparation thereof
JP6859559B2 (ja) * 2017-03-16 2021-04-14 二村　芳弘 抗アレルギー作用を呈するフェニルペプチド誘導体
EP4079748A1 (de) * 2021-04-23 2022-10-26 Insusense ApS Modulatoren von sortilinaktivität

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1206487A (en) * 1968-06-04 1970-09-23 Beecham Group Ltd Derivatives of n-acylaminoacid amides
CH626872A5 (de) * 1976-06-21 1981-12-15 Hoffmann La Roche
PH14141A (en) * 1976-06-25 1981-03-05 Hoffmann La Roche Pharmaceutical composition containing dipeptide derivatives
EP0075160B1 (de) * 1981-09-21 1987-01-07 Toyo Soda Manufacturing Co., Ltd. Verfahren zur Gewinnung eines Dipeptidderivates
US4518528A (en) * 1983-05-19 1985-05-21 Rasnick David W α Amino fluoro ketones
FR2588555B1 (fr) * 1985-10-16 1987-12-11 Atochem Monomeres acryliques fluores, polymeres en derivant et leur application au traitement hydrofuge et oleofuge de substrats divers
EP0269311A3 (de) * 1986-11-17 1990-06-06 Merck & Co. Inc. Methoden zur Behandlung von Knochenleiden mittels Verabreichung von Cystein-Proteinaseinhibitoren
EP0300966B1 (de) * 1987-07-23 1992-10-14 Ciba-Geigy Ag Verfahren zur selektiven N-Acylierung von Amino-hydroxamsäurederivaten und darin verwendete Ausgangsstoffe
JPH02218610A (ja) * 1989-02-21 1990-08-31 Toyo Jozo Co Ltd 骨疾患の予防および治療剤
JP2701932B2 (ja) * 1989-04-10 1998-01-21 サントリー株式会社 タンパク質分解酵素阻害剤
JPH041737A (ja) * 1990-04-19 1992-01-07 Ricoh Co Ltd カメラの絞り装置
EP0504938A3 (en) * 1991-03-22 1993-04-14 Suntory Limited Prophylactic and therapeutic agent for bone diseases comprising di- or tripeptide derivative as active ingredient
US5227401A (en) * 1991-10-29 1993-07-13 G. D. Searle & Co. Ethynyl alanine amino diol compounds for treatment of hypertension

Also Published As

Publication number Publication date
DE69307414T2 (de) 1997-06-26
EP0578978B1 (de) 1997-01-15
JPH05345754A (ja) 1993-12-27
US5399743A (en) 1995-03-21
DE69307414D1 (de) 1997-02-27
EP0578978A1 (de) 1994-01-19

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties