ATE148699T1 - Herstellung von 2-(2-thienyl)äthylamin und synthese von thieno(3,2-c)pyridinderivaten daraus - Google Patents
Herstellung von 2-(2-thienyl)äthylamin und synthese von thieno(3,2-c)pyridinderivaten darausInfo
- Publication number
- ATE148699T1 ATE148699T1 AT92401954T AT92401954T ATE148699T1 AT E148699 T1 ATE148699 T1 AT E148699T1 AT 92401954 T AT92401954 T AT 92401954T AT 92401954 T AT92401954 T AT 92401954T AT E148699 T1 ATE148699 T1 AT E148699T1
- Authority
- AT
- Austria
- Prior art keywords
- thieno
- thienyl
- ethylamine
- pyridine derivatives
- synthesis
- Prior art date
Links
- HVLUYXIJZLDNIS-UHFFFAOYSA-N 2-thiophen-2-ylethanamine Chemical compound NCCC1=CC=CS1 HVLUYXIJZLDNIS-UHFFFAOYSA-N 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- PYEZYNAHBMWJFR-UHFFFAOYSA-N thieno[3,2-c]pyridine Chemical class N1=CC=C2S[C]=CC2=C1 PYEZYNAHBMWJFR-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- ZFSLODLOARCGLH-UHFFFAOYSA-N isocyanuric acid Chemical class OC1=NC(O)=NC(O)=N1 ZFSLODLOARCGLH-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
- MKYRMMMSZSVIGD-UHFFFAOYSA-N thieno[3,2-c]pyridine Chemical class N1=CC=C2SC=CC2=C1 MKYRMMMSZSVIGD-UHFFFAOYSA-N 0.000 abstract 1
- 229960002961 ticlopidine hydrochloride Drugs 0.000 abstract 1
- MTKNGOHFNXIVOS-UHFFFAOYSA-N ticlopidine hydrochloride Chemical compound [H+].[Cl-].ClC1=CC=CC=C1CN1CC(C=CS2)=C2CC1 MTKNGOHFNXIVOS-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72647691A | 1991-07-08 | 1991-07-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE148699T1 true ATE148699T1 (de) | 1997-02-15 |
Family
ID=24918761
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92401954T ATE148699T1 (de) | 1991-07-08 | 1992-07-07 | Herstellung von 2-(2-thienyl)äthylamin und synthese von thieno(3,2-c)pyridinderivaten daraus |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0522956B1 (de) |
| AT (1) | ATE148699T1 (de) |
| AU (1) | AU1947992A (de) |
| CA (1) | CA2073317A1 (de) |
| DE (1) | DE69217282T2 (de) |
| DK (1) | DK0522956T3 (de) |
| ES (1) | ES2097295T3 (de) |
| GR (1) | GR3023276T3 (de) |
| MX (1) | MX9203996A (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI101150B (fi) * | 1991-09-09 | 1998-04-30 | Sankyo Co | Menetelmä lääkeaineina käyttökelpoisten tetrahydrotienopyridiinin johd annaisten valmistamiseksi |
| US5599986A (en) * | 1994-09-29 | 1997-02-04 | Hoechst Marion Roussel Inc. | Process for the preparation of alkali metal salts of diformylamide |
| US6043368A (en) * | 1996-09-04 | 2000-03-28 | Poli Industria Chimica, S.P.A. | Method of making thieno-pyridine derivatives |
| CN102432590B (zh) * | 2011-11-23 | 2013-04-17 | 洛阳师范学院 | 一种噻吩乙胺的合成方法 |
| CN107056801B (zh) * | 2016-11-14 | 2018-12-28 | 太原理工大学 | 一种4,5,6,7-四氢噻吩并[3,2-c]吡啶盐酸盐的合成方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2300090A1 (fr) * | 1975-02-07 | 1976-09-03 | Parcor | Procede de preparation de derives de la thienopyridine |
| US4128561A (en) * | 1975-12-12 | 1978-12-05 | Parcor | Process for the preparation of 2-(2-thienyl)-ethylamine and derivatives thereof |
| LU74545A1 (de) * | 1976-03-12 | 1976-09-01 | ||
| US4906756A (en) * | 1988-05-10 | 1990-03-06 | Syntex (U.S.A.) Inc. | 2-(2-nitrovinyl)thiophene reduction and synthesis of thieno[3,2-c]pyridine derivatives |
| DE69114024T2 (de) * | 1990-01-25 | 1996-05-30 | Sanofi Sa | Herstellung von 2-(2'-Thienyl)alkylaminen und deren Derivaten zur Synthese von 4,5,6,7-Thieno[3,2-c]pyridinderivaten. |
| US4997945A (en) * | 1990-01-25 | 1991-03-05 | Syntex (U.S.A.) Inc. | Carbamate salts of 2-(2'-thienyl)alkylamines |
-
1992
- 1992-07-07 EP EP92401954A patent/EP0522956B1/de not_active Expired - Lifetime
- 1992-07-07 ES ES92401954T patent/ES2097295T3/es not_active Expired - Lifetime
- 1992-07-07 CA CA002073317A patent/CA2073317A1/en not_active Abandoned
- 1992-07-07 DE DE69217282T patent/DE69217282T2/de not_active Expired - Lifetime
- 1992-07-07 AT AT92401954T patent/ATE148699T1/de active
- 1992-07-07 DK DK92401954.0T patent/DK0522956T3/da active
- 1992-07-07 MX MX9203996A patent/MX9203996A/es unknown
- 1992-07-07 AU AU19479/92A patent/AU1947992A/en not_active Abandoned
-
1997
- 1997-04-24 GR GR970400937T patent/GR3023276T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2097295T3 (es) | 1997-04-01 |
| MX9203996A (es) | 1993-02-01 |
| EP0522956A3 (en) | 1993-04-07 |
| AU1947992A (en) | 1993-01-14 |
| GR3023276T3 (en) | 1997-07-30 |
| DE69217282D1 (de) | 1997-03-20 |
| DE69217282T2 (de) | 1997-07-03 |
| EP0522956B1 (de) | 1997-02-05 |
| EP0522956A2 (de) | 1993-01-13 |
| DK0522956T3 (da) | 1997-07-28 |
| CA2073317A1 (en) | 1993-01-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |