ATE143661T1 - Imidazonaphthyridinderivate - Google Patents

Imidazonaphthyridinderivate

Info

Publication number: ATE143661T1
Authority: AT; Austria
Prior art keywords: lower alkyl; substituted; represents hydrogen; hydroxy; unsubstituted
Prior art date: 1990-06-01

Application number

AT91108908T

Other languages

English (en)

Inventor

Fumio Suzuki

Takeshi Kuroda

Shigeto Kitamura

Kenji Ohmori

Original Assignee

Kyowa Hakko Kogyo Kk

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-06-01

Filing date

1991-05-31

Publication date

1996-10-15

1991-05-31 Application filed by Kyowa Hakko Kogyo Kk filed Critical Kyowa Hakko Kogyo Kk

1996-10-15 Application granted granted Critical

1996-10-15 Publication of ATE143661T1 publication Critical patent/ATE143661T1/de

Links

VFTLXHXYGQSOEN-UHFFFAOYSA-N 1h-imidazo[4,5-b][1,8]naphthyridine Chemical class C1=CN=C2NC3=NC=NC3=CC2=C1 VFTLXHXYGQSOEN-UHFFFAOYSA-N 0.000 title abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 6
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
125000003118 aryl group Chemical group 0.000 abstract 3
150000002431 hydrogen Chemical class 0.000 abstract 3
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000004423 acyloxy group Chemical group 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
230000003266 anti-allergic effect Effects 0.000 abstract 1
230000003110 anti-inflammatory effect Effects 0.000 abstract 1
125000001589 carboacyl group Chemical group 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
125000002541 furyl group Chemical group 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
-1 mercapto, hydroxy Chemical group 0.000 abstract 1
125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
230000003389 potentiating effect Effects 0.000 abstract 1
125000004076 pyridyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Luminescent Compositions (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT91108908T 1990-06-01 1991-05-31 Imidazonaphthyridinderivate ATE143661T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP14346090		1990-06-01
JP33465790		1990-11-30

Publications (1)

Publication Number	Publication Date
ATE143661T1 true ATE143661T1 (de)	1996-10-15

Family

ID=26475184

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT91108908T ATE143661T1 (de)	1990-06-01	1991-05-31	Imidazonaphthyridinderivate

Country Status (9)

Country	Link
US (3)	US5364859A (de)
EP (1)	EP0459505B1 (de)
JP (1)	JP3016905B2 (de)
AT (1)	ATE143661T1 (de)
CA (1)	CA2043715C (de)
DE (1)	DE69122427T2 (de)
DK (1)	DK0459505T3 (de)
ES (1)	ES2094772T3 (de)
GR (1)	GR3021971T3 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2094772T3 (es) *	1990-06-01	1997-02-01	Kyowa Hakko Kogyo Kk	Derivados de imidazonaftiridinas.
US5281610A (en) *	1991-07-31	1994-01-25	Kyowa Hakko Kogyo Co., Ltd.	Condensed naphthyridine derivatives
JPH05194515A (ja) *	1991-07-31	1993-08-03	Kyowa Hakko Kogyo Co Ltd	縮合ナフチリジン誘導体
CA2124120A1 (en) *	1991-11-25	1993-06-10	Fumio Suzuki	Imidazonaphthyridine derivatives
WO1994002481A1 (fr) *	1992-07-20	1994-02-03	Kyowa Hakko Kogyo Co., Ltd.	Derive d'imidazonaphtyridine
US6365231B2 (en)	1998-06-26	2002-04-02	Kabushiki Kaisha Toshiba	Ammonium halide eliminator, chemical vapor deposition system and chemical vapor deposition process
JP2000119271A (ja) *	1998-08-12	2000-04-25	Hokuriku Seiyaku Co Ltd	１ｈ―イミダゾピリジン誘導体
CA2715683A1 (en)	1999-08-21	2001-03-01	Nycomed Gmbh	Synergistic combination
US6949247B2 (en)	2000-12-28	2005-09-27	Unilever Home & Personal Care Usa Division Of Conopco, Inc.	Stable skin care compositions containing a retinoid and a retinoid booster system
CN1537018A (zh)	2001-05-23	2004-10-13	田边制药株式会社	一种用于软骨疾病再生治疗的组合物
EP1389468A4 (de)	2001-05-23	2007-01-10	Tanabe Seiyaku Co	Zusammensetzungen zur förderung der knochenfrakturheilung
US7087631B2 (en) *	2002-07-18	2006-08-08	Inotek Pharmaceuticals Corporation	Aryltetrazole compounds, and compositions thereof
US7153824B2 (en)	2003-04-01	2006-12-26	Applied Research Systems Ars Holding N.V.	Inhibitors of phosphodiesterases in infertility
KR20080046728A (ko)	2005-09-15	2008-05-27	아스카 세이야쿠 가부시키가이샤	복소환 화합물, 그의 제조 방법 및 용도
WO2010077530A1 (en) *	2008-12-17	2010-07-08	Merck Patent Gmbh	C-ring modified tricyclic benzonaphthiridinone protein kinase inhibitors and use thereof
US20240124454A1 (en) *	2020-12-31	2024-04-18	Nanjing Zaiming Pharmaceutical Co., Ltd.	Tricyclic compound and use thereof
JP2025503186A (ja) *	2022-01-26	2025-01-30	勤浩医▲葯▼（▲蘇▼州）有限公司	Ｍｔａｐ欠失型がん治療用メチオニンアデノシルトランスフェラーゼ２ａ阻害剤

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RO66801A (fr) *	1973-05-25	1979-08-15	Lepetit Spa	Procede pour obtenir des derives des triazoloizoquinolines
US4059584A (en) *	1974-08-07	1977-11-22	Pfizer	2-Acylamino-3-[3-(dialkylamino)propyl]imidazo[4,5-b]pyridines
IL73534A (en) *	1983-11-18	1990-12-23	Riker Laboratories Inc	1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds
ZA848968B (en) *	1983-11-18	1986-06-25	Riker Laboratories Inc	1h-imidazo(4,5-c)quinolines and 1h-imidazo(4,5-c)quinolin-4-amines
CA1271477A (en) *	1983-11-18	1990-07-10	John F. Gerster	1h-imidazo[4,5-c]quinolin-4-amines
US4760073A (en) *	1986-04-11	1988-07-26	Schering Corporation	Aryl-substituted naphthyridine and pyridopyrazine derivatives, useful as anti-allergic agents
WO1989000571A2 (en) *	1987-07-22	1989-01-26	Schering Corporation	Bicyclic compounds, their use as pharmaceuticals, their preparation, and intermediates useful in their preparation
ES2094772T3 (es) *	1990-06-01	1997-02-01	Kyowa Hakko Kogyo Kk	Derivados de imidazonaftiridinas.

1991
- 1991-05-31 ES ES91108908T patent/ES2094772T3/es not_active Expired - Lifetime
- 1991-05-31 JP JP3129651A patent/JP3016905B2/ja not_active Expired - Fee Related
- 1991-05-31 EP EP91108908A patent/EP0459505B1/de not_active Expired - Lifetime
- 1991-05-31 AT AT91108908T patent/ATE143661T1/de not_active IP Right Cessation
- 1991-05-31 DK DK91108908.4T patent/DK0459505T3/da active
- 1991-05-31 CA CA002043715A patent/CA2043715C/en not_active Expired - Fee Related
- 1991-05-31 DE DE69122427T patent/DE69122427T2/de not_active Expired - Fee Related
1992
- 1992-12-29 US US07/999,658 patent/US5364859A/en not_active Expired - Fee Related
1994
- 1994-05-12 US US08/241,631 patent/US5468756A/en not_active Expired - Fee Related
1995
- 1995-09-11 US US08/526,323 patent/US5536730A/en not_active Expired - Fee Related
1996
- 1996-12-11 GR GR960403401T patent/GR3021971T3/el unknown

Also Published As

Publication number	Publication date
JPH04226985A (ja)	1992-08-17
JP3016905B2 (ja)	2000-03-06
US5536730A (en)	1996-07-16
CA2043715C (en)	1997-01-07
DE69122427D1 (de)	1996-11-07
GR3021971T3 (en)	1997-03-31
CA2043715A1 (en)	1991-12-02
EP0459505B1 (de)	1996-10-02
US5364859A (en)	1994-11-15
ES2094772T3 (es)	1997-02-01
US5468756A (en)	1995-11-21
DE69122427T2 (de)	1997-03-06
DK0459505T3 (da)	1996-11-18
EP0459505A1 (de)	1991-12-04

Legal Events

Date	Code	Title	Description
1997-04-15	UEP	Publication of translation of european patent specification
2003-02-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE143661T1 (de)	1996-10-15	Imidazonaphthyridinderivate
DE69120581D1 (de)	1996-08-08	1,8-Naphthyridin-2-on-Derivate
ES2094204T3 (es)	1997-01-16	Derivados de piperazina.
NO882626D0 (no)	1988-06-15	Fremgangsmaate for fremstilling av farmakologisk aktive pyridin-derivater.
NO910804D0 (no)	1991-02-28	Substituerte beta-diketoner.
ES2109936T3 (es)	1998-02-01	Derivados de piperacina.
SE8901060D0 (sv)	1989-03-28	New compounds
ATE148699T1 (de)	1997-02-15	Herstellung von 2-(2-thienyl)äthylamin und synthese von thieno(3,2-c)pyridinderivaten daraus
DE69103985D1 (de)	1994-10-20	N-Alkylthiazolidinderivate.
DE69303847D1 (de)	1996-09-05	Indolderivate
ATE155785T1 (de)	1997-08-15	Mitomycinderivate
DE60103732D1 (de)	2004-07-15	Pyrimidinderivate mit antitumor-wirkung
ES2076995T3 (es)	1995-11-16	Procedimiento para preparar derivados de carbamato de lankacidina.