ATE149156T1 - 3-aryl-2-hydroxypropionsäurederivate und analoge als hypoglykämische mittel - Google Patents

3-aryl-2-hydroxypropionsäurederivate und analoge als hypoglykämische mittel

Info

Publication number
ATE149156T1
ATE149156T1 AT91911285T AT91911285T ATE149156T1 AT E149156 T1 ATE149156 T1 AT E149156T1 AT 91911285 T AT91911285 T AT 91911285T AT 91911285 T AT91911285 T AT 91911285T AT E149156 T1 ATE149156 T1 AT E149156T1
Authority
AT
Austria
Prior art keywords
acid derivatives
analogues
aryl
hydroxypropionic acid
hypoglycemic agents
Prior art date
Application number
AT91911285T
Other languages
English (en)
Inventor
Bernard Hulin
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE149156T1 publication Critical patent/ATE149156T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Detergent Compositions (AREA)
AT91911285T 1990-06-14 1991-05-31 3-aryl-2-hydroxypropionsäurederivate und analoge als hypoglykämische mittel ATE149156T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/537,673 US5089514A (en) 1990-06-14 1990-06-14 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents

Publications (1)

Publication Number Publication Date
ATE149156T1 true ATE149156T1 (de) 1997-03-15

Family

ID=24143633

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91911285T ATE149156T1 (de) 1990-06-14 1991-05-31 3-aryl-2-hydroxypropionsäurederivate und analoge als hypoglykämische mittel

Country Status (21)

Country Link
US (3) US5089514A (de)
EP (1) EP0533781B1 (de)
JP (2) JPH075513B2 (de)
KR (1) KR930700492A (de)
AT (1) ATE149156T1 (de)
AU (1) AU646052B2 (de)
CA (1) CA2084898A1 (de)
DE (1) DE69124798T2 (de)
DK (1) DK0533781T3 (de)
ES (1) ES2098356T3 (de)
FI (1) FI925640A7 (de)
GR (1) GR3022714T3 (de)
HU (1) HUT65603A (de)
IE (1) IE912003A1 (de)
IL (1) IL98447A (de)
MY (1) MY106380A (de)
NO (1) NO924799L (de)
NZ (1) NZ238528A (de)
PT (1) PT97950B (de)
WO (1) WO1991019702A1 (de)
ZA (1) ZA914519B (de)

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MY106380A (en) 1995-05-30
ES2098356T3 (es) 1997-05-01
JP2581523B2 (ja) 1997-02-12
HUT65603A (en) 1994-07-28
FI925640L (fi) 1992-12-11
JPH05507920A (ja) 1993-11-11
EP0533781A1 (de) 1993-03-31
US5306726A (en) 1994-04-26
US5438074A (en) 1995-08-01
FI925640A0 (fi) 1992-12-11
EP0533781B1 (de) 1997-02-26
US5089514A (en) 1992-02-18
PT97950B (pt) 1998-11-30
AU646052B2 (en) 1994-02-03
JPH07149636A (ja) 1995-06-13
DE69124798T2 (de) 1997-06-12
CA2084898A1 (en) 1991-12-15
WO1991019702A1 (en) 1991-12-26
GR3022714T3 (en) 1997-06-30
HU9203943D0 (en) 1993-03-29
IL98447A (en) 1995-12-31
NO924799D0 (no) 1992-12-11
NZ238528A (en) 1993-07-27
IL98447A0 (en) 1992-07-15
KR930700492A (ko) 1993-03-15
FI925640A7 (fi) 1992-12-11
IE912003A1 (en) 1991-12-18
ZA914519B (en) 1993-01-27
DE69124798D1 (de) 1997-04-03
PT97950A (pt) 1992-03-31
AU7995691A (en) 1992-01-07
JPH075513B2 (ja) 1995-01-25
DK0533781T3 (da) 1997-07-07
NO924799L (no) 1992-12-14

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