ATE150793T1 - Markierte verbindungen zur verwendung in einem diagnostischen atemtest - Google Patents

Markierte verbindungen zur verwendung in einem diagnostischen atemtest

Info

Publication number
ATE150793T1
ATE150793T1 AT91911157T AT91911157T ATE150793T1 AT E150793 T1 ATE150793 T1 AT E150793T1 AT 91911157 T AT91911157 T AT 91911157T AT 91911157 T AT91911157 T AT 91911157T AT E150793 T1 ATE150793 T1 AT E150793T1
Authority
AT
Austria
Prior art keywords
microorganisms
breath test
oils
produce
labeled
Prior art date
Application number
AT91911157T
Other languages
English (en)
Inventor
David John Kyle
Original Assignee
Martek Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Martek Corp filed Critical Martek Corp
Application granted granted Critical
Publication of ATE150793T1 publication Critical patent/ATE150793T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1206—Administration of radioactive gases, aerosols or breath tests
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B1/00—Production of fats or fatty oils from raw materials
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06—Lysis of microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6463—Glycerides obtained from glyceride producing microorganisms, e.g. single cell oil
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/946—Microorganisms using algae

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Analytical Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Atmospheric Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
AT91911157T 1990-05-21 1991-05-13 Markierte verbindungen zur verwendung in einem diagnostischen atemtest ATE150793T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/525,820 US5164308A (en) 1990-05-21 1990-05-21 Preparation of labelled triglyceride oils by cultivation of microorganisms

Publications (1)

Publication Number Publication Date
ATE150793T1 true ATE150793T1 (de) 1997-04-15

Family

ID=24094735

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91911157T ATE150793T1 (de) 1990-05-21 1991-05-13 Markierte verbindungen zur verwendung in einem diagnostischen atemtest

Country Status (7)

Country Link
US (3) US5164308A (de)
EP (1) EP0533775B1 (de)
JP (1) JPH05507275A (de)
AT (1) ATE150793T1 (de)
CA (1) CA2083041C (de)
DE (1) DE69125373T2 (de)
WO (1) WO1991018105A1 (de)

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US6334997B1 (en) 1994-03-25 2002-01-01 Isotechnika, Inc. Method of using deuterated calcium channel blockers
CN1087725C (zh) * 1994-03-25 2002-07-17 同位素技术有限公司 用氘代方法增强药物效果
WO1997018321A1 (en) * 1995-11-15 1997-05-22 Martek Corporation Photosynthetic production of stable isotopically labeled recombinant proteins
US5707602A (en) * 1996-03-25 1998-01-13 Meretek Diagnostics Measurement of gastric emptying
AU2956397A (en) * 1996-05-15 1997-12-05 Gist-Brocades B.V. Sterol extraction with polar solvent to give low sterol, high triglyceride, microbial oil
US5785949A (en) * 1996-09-05 1998-07-28 Meretek Diagnostics Measurement of liquid phase gastric emptying
CA2249173C (en) * 1997-10-06 2008-12-16 Tokyo Gas Co., Ltd. Diagnostic agent for liver function
CA2250485C (en) * 1997-10-21 2008-04-29 Tokyo Gas Co., Ltd. Diagnostic agent for diabetes
US6284219B1 (en) 1998-06-30 2001-09-04 Phenome Sciences Inc. In vivo determination of metabolic function for use in therapy management
EP1006198A1 (de) * 1998-12-01 2000-06-07 Meretek Diagnostics Ein nicht-invasives Verfahren zur funktionellen Feststellung von Säuglingen und Kindern mit einer ererbten metabolischen Störung
US6291241B1 (en) * 1999-03-29 2001-09-18 Trevor Percival Castor Methods for making Hypericum fractions and St. John's Wort products
AU2001252559B2 (en) * 2000-05-02 2005-09-15 Otsuka Pharmaceutical Co., Ltd. Preparations for evaluating eliminative ability of stomach
WO2002099123A1 (en) * 2001-06-05 2002-12-12 The Children's Hospital Of Philadelphia Methods and kits for diagnosing a pancreatic-based fat malabsorption disorder
US20050281745A1 (en) * 2002-03-22 2005-12-22 Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center Stable isotope based dynamic metabolic profiling of living organisms for characterization of metabolic diseases, drug testing and drug development
JP4088097B2 (ja) * 2002-04-26 2008-05-21 サントリー株式会社 高度不飽和脂肪酸含有脂質の製造方法
US7695971B2 (en) * 2003-08-06 2010-04-13 Children's Hospital Medical Center Use of non-absorbable fat in determining dietary fat absorption
US20060188444A1 (en) * 2005-02-23 2006-08-24 Otsuka Pharmaceutical Co., Ltd. Method for monitoring patient or subject compliance with medical prescriptions, and formulation for use in the method
US20090041662A1 (en) * 2005-02-23 2009-02-12 Irie Yasuo Method for Monitoring Patient or Subject Compliance with Medical Prescriptions, and Formulation for Use in the Method
EP2371967B1 (de) 2005-03-18 2015-06-03 DSM IP Assets B.V. Produktion von Carotenoiden in Ölhaltigen Hefen und Pilzen
DK2447356T3 (en) 2005-06-07 2016-06-06 Dsm Nutritional Products Ag Eukaryotic MICROORGANISMS FOR PRODUCTION OF LIPIDS AND ANTIOXIDANTS
CN101232905B (zh) 2005-07-25 2013-01-09 大塚制药株式会社 一种用于测量嘧啶代谢能力的口服制剂
US9162953B2 (en) * 2006-07-05 2015-10-20 Centre Nationale De Recherche Scientifique Iron-copper co-catalyzed process for carbon-carbon or carbon-heteroatom bonding
WO2008129358A2 (en) 2006-08-01 2008-10-30 Ocean Nutrition Canada Ltd. Oil producing microbes and methods of modification thereof
FR2904773B1 (fr) * 2006-08-11 2008-11-07 Lvmh Rech Composition cosmetique amincissante contenant un extrait de biomasse de l'algue neochloris oleoabundans
US8691555B2 (en) 2006-09-28 2014-04-08 Dsm Ip Assests B.V. Production of carotenoids in oleaginous yeast and fungi
CN104212844A (zh) 2007-06-01 2014-12-17 索拉兹米公司 在微生物中生产油
RU2361922C1 (ru) * 2007-11-19 2009-07-20 Лимнологический институт Сибирского отделения Российской академии наук Способ получения изотопномеченых 13c полиненасыщенных жирных кислот
MX338039B (es) * 2008-04-09 2016-03-30 Solazyme Inc Modificacion quimica directa de biomasa bacteriana y aceites microbianos.
US20100303989A1 (en) 2008-10-14 2010-12-02 Solazyme, Inc. Microalgal Flour
US20160324167A1 (en) 2008-10-14 2016-11-10 Terravia Holdings, Inc. Novel microalgal food compositions
US8809037B2 (en) 2008-10-24 2014-08-19 Bioprocessh20 Llc Systems, apparatuses and methods for treating wastewater
EP2370554B1 (de) 2008-11-28 2019-05-15 Corbion Biotech, Inc. Herstellung von massgeschneiderten ölen in rekombinanten heterotrophen mikroorganismen
US8709750B2 (en) * 2008-12-15 2014-04-29 Cavitation Technologies, Inc. Method for processing an algae medium containing algae microorganisms to produce algal oil and by-products
CN102498200B (zh) * 2009-07-28 2014-11-26 焦耳无限科技公司 光生物反应器、太阳能收集系统、以及热控制方法
US20110177564A1 (en) * 2010-01-15 2011-07-21 Massachusetts Institute Of Technology Bioprocess and microbe engineering for total carbon utilization in biofuel production
EP2576800B1 (de) 2010-05-28 2019-01-30 Corbion Biotech, Inc. Verfahren zur Herstellung von Ölen aus Prototheca
AU2011323288B2 (en) 2010-11-03 2016-05-26 Corbion Biotech, Inc. Microbial oils with lowered pour points, dielectric fluids produced therefrom, and related methods
AU2012212079B2 (en) 2011-02-02 2016-07-28 Corbion Biotech, Inc. Tailored oils produced from recombinant oleaginous microorganisms
MX339607B (es) 2011-05-06 2016-05-31 Solazyme Inc Microorganismos geneticamente modificados que metabolizan xilosa.
JP2014185189A (ja) * 2011-07-14 2014-10-02 Ajinomoto Co Inc 脂肪酸類の製造法
EP2839018B1 (de) 2012-04-18 2019-06-05 Corbion Biotech, Inc. Massgeschneiderte öle
KR102105354B1 (ko) 2012-08-20 2020-04-29 오츠카 세이야쿠 가부시키가이샤 당대사능의 측정 방법 및 그에 사용하는 조성물
US10098371B2 (en) 2013-01-28 2018-10-16 Solazyme Roquette Nutritionals, LLC Microalgal flour
EP2970926B1 (de) 2013-03-13 2018-01-31 DSM Nutritional Products AG Manipulation von mikroorganismen
ES2754246T3 (es) 2013-03-15 2020-04-16 Otsuka Pharma Co Ltd Composición para su uso en un método para medir la razón de combustión azúcar/ácido graso
US9249252B2 (en) * 2013-04-26 2016-02-02 Solazyme, Inc. Low polyunsaturated fatty acid oils and uses thereof
FR3009619B1 (fr) 2013-08-07 2017-12-29 Roquette Freres Compositions de biomasse de microalgues riches en proteines de qualite sensorielle optimisee
CN105829521A (zh) 2013-10-04 2016-08-03 索拉兹米公司 定制油
EP3167053B1 (de) 2014-07-10 2019-10-09 Corbion Biotech, Inc. Neuartige ketoacyl-acp-synthasegene und verwendungen davon
AR104042A1 (es) 2015-03-26 2017-06-21 Mara Renewables Corp Producción de alta densidad de biomasa y aceite utilizando glicerol en bruto
AU2016293487B2 (en) 2015-07-13 2021-07-01 MARA Renewables Corporation Enhancing microalgal metabolism of xylose
US10851395B2 (en) 2016-06-10 2020-12-01 MARA Renewables Corporation Method of making lipids with improved cold flow properties
US20240216321A1 (en) 2022-12-02 2024-07-04 Dsm Ip Assets B.V. Fermentatively-produced retinoid containing compositions, and the methdos of making and using the same

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Also Published As

Publication number Publication date
US5164308A (en) 1992-11-17
US5466434A (en) 1995-11-14
EP0533775A4 (en) 1993-06-30
EP0533775A1 (de) 1993-03-31
EP0533775B1 (de) 1997-03-26
DE69125373D1 (de) 1997-04-30
CA2083041A1 (en) 1991-11-22
CA2083041C (en) 2003-07-22
DE69125373T2 (de) 1997-09-25
WO1991018105A1 (en) 1991-11-28
JPH05507275A (ja) 1993-10-21
US5376540A (en) 1994-12-27

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