ATE150793T1 - Markierte verbindungen zur verwendung in einem diagnostischen atemtest - Google Patents

Markierte verbindungen zur verwendung in einem diagnostischen atemtest

Info

Publication number
ATE150793T1
ATE150793T1 AT91911157T AT91911157T ATE150793T1 AT E150793 T1 ATE150793 T1 AT E150793T1 AT 91911157 T AT91911157 T AT 91911157T AT 91911157 T AT91911157 T AT 91911157T AT E150793 T1 ATE150793 T1 AT E150793T1
Authority
AT
Austria
Prior art keywords
microorganisms
breath test
oils
produce
labeled
Prior art date
Application number
AT91911157T
Other languages
English (en)
Inventor
David John Kyle
Original Assignee
Martek Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Martek Corp filed Critical Martek Corp
Application granted granted Critical
Publication of ATE150793T1 publication Critical patent/ATE150793T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1206—Administration of radioactive gases, aerosols or breath tests
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B1/00—Production of fats or fatty oils from raw materials
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06—Lysis of microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6463—Glycerides obtained from glyceride producing microorganisms, e.g. single cell oil
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/946—Microorganisms using algae

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Optics & Photonics (AREA)
  • Dispersion Chemistry (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Atmospheric Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
AT91911157T 1990-05-21 1991-05-13 Markierte verbindungen zur verwendung in einem diagnostischen atemtest ATE150793T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/525,820 US5164308A (en) 1990-05-21 1990-05-21 Preparation of labelled triglyceride oils by cultivation of microorganisms

Publications (1)

Publication Number Publication Date
ATE150793T1 true ATE150793T1 (de) 1997-04-15

Family

ID=24094735

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91911157T ATE150793T1 (de) 1990-05-21 1991-05-13 Markierte verbindungen zur verwendung in einem diagnostischen atemtest

Country Status (7)

Country Link
US (3) US5164308A (de)
EP (1) EP0533775B1 (de)
JP (1) JPH05507275A (de)
AT (1) ATE150793T1 (de)
CA (1) CA2083041C (de)
DE (1) DE69125373T2 (de)
WO (1) WO1991018105A1 (de)

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US6334997B1 (en) 1994-03-25 2002-01-01 Isotechnika, Inc. Method of using deuterated calcium channel blockers
ES2293638T3 (es) * 1994-03-25 2008-03-16 Isotechnika, Inc. Mejora de la eficacia de farmacos por deuteracion.
WO1997018321A1 (en) * 1995-11-15 1997-05-22 Martek Corporation Photosynthetic production of stable isotopically labeled recombinant proteins
US5707602A (en) * 1996-03-25 1998-01-13 Meretek Diagnostics Measurement of gastric emptying
US6166230A (en) * 1996-05-15 2000-12-26 Gist-Brocades B.V. Sterol extraction with polar solvent to give low sterol, high triglyceride, microbial oil
US5785949A (en) * 1996-09-05 1998-07-28 Meretek Diagnostics Measurement of liquid phase gastric emptying
CA2249173C (en) * 1997-10-06 2008-12-16 Tokyo Gas Co., Ltd. Diagnostic agent for liver function
CA2250485C (en) * 1997-10-21 2008-04-29 Tokyo Gas Co., Ltd. Diagnostic agent for diabetes
US6284219B1 (en) 1998-06-30 2001-09-04 Phenome Sciences Inc. In vivo determination of metabolic function for use in therapy management
EP1006198A1 (de) * 1998-12-01 2000-06-07 Meretek Diagnostics Ein nicht-invasives Verfahren zur funktionellen Feststellung von Säuglingen und Kindern mit einer ererbten metabolischen Störung
US6291241B1 (en) * 1999-03-29 2001-09-18 Trevor Percival Castor Methods for making Hypericum fractions and St. John's Wort products
EP1285668A4 (de) * 2000-05-02 2007-07-11 Otsuka Pharma Co Ltd Zusammensetzungen zur feststellung der eliminationsgeschwindigkeit im magen
US7402405B2 (en) * 2001-06-05 2008-07-22 The Children's Hospital Of Philadelphia Methods and kits for diagnosing a pancreatic-based fat malabsorption disorder
US20050281745A1 (en) * 2002-03-22 2005-12-22 Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center Stable isotope based dynamic metabolic profiling of living organisms for characterization of metabolic diseases, drug testing and drug development
JP4088097B2 (ja) * 2002-04-26 2008-05-21 サントリー株式会社 高度不飽和脂肪酸含有脂質の製造方法
US7695971B2 (en) * 2003-08-06 2010-04-13 Children's Hospital Medical Center Use of non-absorbable fat in determining dietary fat absorption
US20090041662A1 (en) * 2005-02-23 2009-02-12 Irie Yasuo Method for Monitoring Patient or Subject Compliance with Medical Prescriptions, and Formulation for Use in the Method
US20060188444A1 (en) * 2005-02-23 2006-08-24 Otsuka Pharmaceutical Co., Ltd. Method for monitoring patient or subject compliance with medical prescriptions, and formulation for use in the method
CN103589650A (zh) 2005-03-18 2014-02-19 米克罗比亚公司 产油酵母和真菌中类胡萝卜素的产生
ES2626018T3 (es) 2005-06-07 2017-07-21 Dsm Nutritional Products Ag Microorganismos eucariotas para la producción de lípidos y antioxidantes
PT1920786E (pt) 2005-07-25 2011-12-28 Otsuka Pharma Co Ltd Preparação oral para avaliar a capacidade metabólica da pirimidina
WO2008004088A2 (en) * 2006-07-05 2008-01-10 Centre National De La Recherche Scientifique (C.N.R.S.) Iron-copper co-catalyzed process for carbon-carbon or carbon-heteroatom bonding
CN101981201A (zh) 2006-08-01 2011-02-23 加拿大海洋营养食品有限公司 产油微生物及改良这些微生物的方法
FR2904773B1 (fr) * 2006-08-11 2008-11-07 Lvmh Rech Composition cosmetique amincissante contenant un extrait de biomasse de l'algue neochloris oleoabundans
WO2008042338A2 (en) 2006-09-28 2008-04-10 Microbia, Inc. Production of carotenoids in oleaginous yeast and fungi
US20090004715A1 (en) 2007-06-01 2009-01-01 Solazyme, Inc. Glycerol Feedstock Utilization for Oil-Based Fuel Manufacturing
RU2361922C1 (ru) * 2007-11-19 2009-07-20 Лимнологический институт Сибирского отделения Российской академии наук Способ получения изотопномеченых 13c полиненасыщенных жирных кислот
CA2720828C (en) * 2008-04-09 2017-03-21 Solazyme, Inc. Direct chemical modification of microbial biomass and microbial oils
US20160324167A1 (en) 2008-10-14 2016-11-10 Terravia Holdings, Inc. Novel microalgal food compositions
US20100303989A1 (en) 2008-10-14 2010-12-02 Solazyme, Inc. Microalgal Flour
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US8709750B2 (en) * 2008-12-15 2014-04-29 Cavitation Technologies, Inc. Method for processing an algae medium containing algae microorganisms to produce algal oil and by-products
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WO2011088364A2 (en) * 2010-01-15 2011-07-21 Massachuseits Institute Of Technology Bioprocess and microbe engineering for total carbon utilization in biofuelproduction
US8592188B2 (en) 2010-05-28 2013-11-26 Solazyme, Inc. Tailored oils produced from recombinant heterotrophic microorganisms
EP2635663B1 (de) 2010-11-03 2019-05-08 Corbion Biotech, Inc. Mikrobielle öle mit redzuzierten giesspunkten, dielektrische flüssigkeiten daraus und zugehörige verfahren
KR101964965B1 (ko) 2011-02-02 2019-04-03 테라비아 홀딩스 인코포레이티드 재조합 유지성 미생물로부터 생산된 맞춤 오일
MX339607B (es) 2011-05-06 2016-05-31 Solazyme Inc Microorganismos geneticamente modificados que metabolizan xilosa.
JP2014185189A (ja) * 2011-07-14 2014-10-02 Ajinomoto Co Inc 脂肪酸類の製造法
US8945908B2 (en) 2012-04-18 2015-02-03 Solazyme, Inc. Tailored oils
CA2882528A1 (en) 2012-08-20 2014-02-27 Otsuka Pharmaceutical Co., Ltd. Method for measuring carbohydrate metabolism ability, and composition for use in said method
US10098371B2 (en) 2013-01-28 2018-10-16 Solazyme Roquette Nutritionals, LLC Microalgal flour
DK2970926T3 (en) 2013-03-13 2018-04-16 Dsm Nutritional Products Ag GENMANIPULATION OF MICROorganisms
KR20210014204A (ko) 2013-03-15 2021-02-08 오츠카 세이야쿠 가부시키가이샤 지방산 연소에 의한 인슐린 저항성의 측정 방법, 및 그에 사용하는 조성물
EP2993993A2 (de) * 2013-04-26 2016-03-16 Solazyme, Inc. Öle mit niedrigem gehalt an mehrfach ungesättigten fettsäuren und verwendungen davon
FR3009619B1 (fr) 2013-08-07 2017-12-29 Roquette Freres Compositions de biomasse de microalgues riches en proteines de qualite sensorielle optimisee
MX369685B (es) 2013-10-04 2019-11-19 Terravia Holdings Inc Aceites adaptables.
US9969990B2 (en) 2014-07-10 2018-05-15 Corbion Biotech, Inc. Ketoacyl ACP synthase genes and uses thereof
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CA2991707C (en) 2015-07-13 2023-08-01 MARA Renewables Corporation Enhancing microbial metabolism of c5 organic carbon
US10851395B2 (en) 2016-06-10 2020-12-01 MARA Renewables Corporation Method of making lipids with improved cold flow properties
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Also Published As

Publication number Publication date
CA2083041A1 (en) 1991-11-22
EP0533775A4 (en) 1993-06-30
US5164308A (en) 1992-11-17
JPH05507275A (ja) 1993-10-21
EP0533775B1 (de) 1997-03-26
EP0533775A1 (de) 1993-03-31
DE69125373T2 (de) 1997-09-25
DE69125373D1 (de) 1997-04-30
WO1991018105A1 (en) 1991-11-28
CA2083041C (en) 2003-07-22
US5466434A (en) 1995-11-14
US5376540A (en) 1994-12-27

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