ATE150793T1 - Markierte verbindungen zur verwendung in einem diagnostischen atemtest - Google Patents

Markierte verbindungen zur verwendung in einem diagnostischen atemtest

Info

Publication number
ATE150793T1
ATE150793T1 AT91911157T AT91911157T ATE150793T1 AT E150793 T1 ATE150793 T1 AT E150793T1 AT 91911157 T AT91911157 T AT 91911157T AT 91911157 T AT91911157 T AT 91911157T AT E150793 T1 ATE150793 T1 AT E150793T1
Authority
AT
Austria
Prior art keywords
microorganisms
breath test
oils
produce
labeled
Prior art date
Application number
AT91911157T
Other languages
English (en)
Inventor
David John Kyle
Original Assignee
Martek Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Martek Corp filed Critical Martek Corp
Application granted granted Critical
Publication of ATE150793T1 publication Critical patent/ATE150793T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1206—Administration of radioactive gases, aerosols or breath tests
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B1/00—Production of fats or fatty oils from raw materials
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06—Lysis of microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6463—Glycerides obtained from glyceride producing microorganisms, e.g. single cell oil
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/946—Microorganisms using algae

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Virology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Atmospheric Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Mycology (AREA)
  • Cell Biology (AREA)
AT91911157T 1990-05-21 1991-05-13 Markierte verbindungen zur verwendung in einem diagnostischen atemtest ATE150793T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/525,820 US5164308A (en) 1990-05-21 1990-05-21 Preparation of labelled triglyceride oils by cultivation of microorganisms

Publications (1)

Publication Number Publication Date
ATE150793T1 true ATE150793T1 (de) 1997-04-15

Family

ID=24094735

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91911157T ATE150793T1 (de) 1990-05-21 1991-05-13 Markierte verbindungen zur verwendung in einem diagnostischen atemtest

Country Status (7)

Country Link
US (3) US5164308A (de)
EP (1) EP0533775B1 (de)
JP (1) JPH05507275A (de)
AT (1) ATE150793T1 (de)
CA (1) CA2083041C (de)
DE (1) DE69125373T2 (de)
WO (1) WO1991018105A1 (de)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3354582B2 (ja) * 1991-09-30 2002-12-09 サントリー株式会社 オメガ９系高度不飽和脂肪酸およびこれを含有する脂質の製造方法
US6569640B1 (en) * 1993-03-12 2003-05-27 Aphios Corporation Method of fractionation of biologically-derived materials using critical fluids
ES2293638T3 (es) * 1994-03-25 2008-03-16 Isotechnika, Inc. Mejora de la eficacia de farmacos por deuteracion.
US6334997B1 (en) 1994-03-25 2002-01-01 Isotechnika, Inc. Method of using deuterated calcium channel blockers
AU7731696A (en) * 1995-11-15 1997-06-05 Martek Corporation Photosynthetic production of stable isotopically labeled recombinant proteins
US5707602A (en) * 1996-03-25 1998-01-13 Meretek Diagnostics Measurement of gastric emptying
ES2175409T5 (es) * 1996-05-15 2007-05-01 Dsm Ip Assets B.V. Extraccion de esterol con un disolvente polar para dar un aceite microbiano bajo en esterol.
US5785949A (en) * 1996-09-05 1998-07-28 Meretek Diagnostics Measurement of liquid phase gastric emptying
CA2249173C (en) * 1997-10-06 2008-12-16 Tokyo Gas Co., Ltd. Diagnostic agent for liver function
CA2250485C (en) * 1997-10-21 2008-04-29 Tokyo Gas Co., Ltd. Diagnostic agent for diabetes
US6284219B1 (en) 1998-06-30 2001-09-04 Phenome Sciences Inc. In vivo determination of metabolic function for use in therapy management
EP1006198A1 (de) * 1998-12-01 2000-06-07 Meretek Diagnostics Ein nicht-invasives Verfahren zur funktionellen Feststellung von Säuglingen und Kindern mit einer ererbten metabolischen Störung
US6291241B1 (en) * 1999-03-29 2001-09-18 Trevor Percival Castor Methods for making Hypericum fractions and St. John's Wort products
KR20030007567A (ko) * 2000-05-02 2003-01-23 오츠카 세이야쿠 가부시키가이샤 위 배설 능력 측정용 제제
EP1404861A4 (de) * 2001-06-05 2006-02-01 Philadelphia Children Hospital Verfahren und kits zur diagnose einer fett-malabsorptionsstörung mit ursache im pankreas
US20050281745A1 (en) * 2002-03-22 2005-12-22 Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center Stable isotope based dynamic metabolic profiling of living organisms for characterization of metabolic diseases, drug testing and drug development
JP4088097B2 (ja) * 2002-04-26 2008-05-21 サントリー株式会社 高度不飽和脂肪酸含有脂質の製造方法
US7695971B2 (en) * 2003-08-06 2010-04-13 Children's Hospital Medical Center Use of non-absorbable fat in determining dietary fat absorption
US20060188444A1 (en) * 2005-02-23 2006-08-24 Otsuka Pharmaceutical Co., Ltd. Method for monitoring patient or subject compliance with medical prescriptions, and formulation for use in the method
US20090041662A1 (en) * 2005-02-23 2009-02-12 Irie Yasuo Method for Monitoring Patient or Subject Compliance with Medical Prescriptions, and Formulation for Use in the Method
BRPI0609040B1 (pt) 2005-03-18 2018-07-31 Microbia, Inc. Fungo recombinante do gênero yarrowia, método de produção de um carotenóide e método de preparo de um aditivo alimentício ou ração contendo um carotenóide
EP3467096B1 (de) 2005-06-07 2022-01-12 DSM Nutritional Products AG Eukaryotische mikroorganismen zur herstellung von lipiden und antioxidantien
EP1920786B8 (de) 2005-07-25 2012-02-22 Otsuka Pharmaceutical Co., Ltd. Orales präparat zur messung der fähigkeit pyrimidin zu metabolisieren
EP2043970B1 (de) * 2006-07-05 2018-04-18 Centre National De La Recherche Scientifique (C.N.R.S.) Co-katalysiertes eisen-kupfer-verfahren für kohlenstoff-kohlenstoff- oder kohlenstoff-heteroatom-bindung
ES2572833T3 (es) 2006-08-01 2016-06-02 Dsm Nutritional Products Ag Proceso de producción de aceite microbiano que contiene ácidos grasos poliinsaturados
FR2904773B1 (fr) * 2006-08-11 2008-11-07 Lvmh Rech Composition cosmetique amincissante contenant un extrait de biomasse de l'algue neochloris oleoabundans
EP2078092A2 (de) 2006-09-28 2009-07-15 Microbia, Inc. Herstellung von carotenoiden in öliger hefe und pilzen
CN104212844A (zh) 2007-06-01 2014-12-17 索拉兹米公司 在微生物中生产油
RU2361922C1 (ru) * 2007-11-19 2009-07-20 Лимнологический институт Сибирского отделения Российской академии наук Способ получения изотопномеченых 13c полиненасыщенных жирных кислот
AU2009234176B2 (en) * 2008-04-09 2014-08-07 Corbion Biotech, Inc. Direct chemical modification of microbial biomass and microbial oils
US20160324167A1 (en) 2008-10-14 2016-11-10 Terravia Holdings, Inc. Novel microalgal food compositions
US20100303989A1 (en) 2008-10-14 2010-12-02 Solazyme, Inc. Microalgal Flour
US8809037B2 (en) 2008-10-24 2014-08-19 Bioprocessh20 Llc Systems, apparatuses and methods for treating wastewater
CN102712858B (zh) 2008-11-28 2015-08-12 索拉兹米公司 在重组异养型微生物中制备特制油
US8709750B2 (en) * 2008-12-15 2014-04-29 Cavitation Technologies, Inc. Method for processing an algae medium containing algae microorganisms to produce algal oil and by-products
AU2010281397B2 (en) * 2009-07-28 2014-11-06 Joule Unlimited Technologies, Inc. Photobioreactors, solar energy gathering systems, and thermal control methods
US20110177564A1 (en) * 2010-01-15 2011-07-21 Massachusetts Institute Of Technology Bioprocess and microbe engineering for total carbon utilization in biofuel production
CN106135460B (zh) 2010-05-28 2020-07-24 柯碧恩生物技术公司 包含特制油的食品组合物
CA2816125C (en) 2010-11-03 2018-12-11 Solazyme, Inc. Microbial oils with lowered pour points, dielectric fluids produced therefrom, and related methods
CA2825691C (en) 2011-02-02 2020-08-25 Solazyme, Inc. Tailored oils produced from recombinant oleaginous microorganisms
EP2705138B1 (de) 2011-05-06 2017-03-22 TerraVia Holdings, Inc. Genetisch modifizierte mikroorganismen zur verstoffwechselung von xylose
JP2014185189A (ja) * 2011-07-14 2014-10-02 Ajinomoto Co Inc 脂肪酸類の製造法
AU2013249172C1 (en) 2012-04-18 2017-08-10 Corbion Biotech, Inc. Tailored oils
JP6352188B2 (ja) 2012-08-20 2018-07-04 大塚製薬株式会社 糖代謝能の測定方法及びそれに使用する組成物
US10098371B2 (en) 2013-01-28 2018-10-16 Solazyme Roquette Nutritionals, LLC Microalgal flour
US9873880B2 (en) 2013-03-13 2018-01-23 Dsm Nutritional Products Ag Engineering microorganisms
EP2975400B1 (de) 2013-03-15 2019-09-04 Otsuka Pharmaceutical Co., Ltd. Zusammensetzung zur verwendung in einem verfahren zur messung des zucker- / fettsäureverbrennungsverhältnisses
EP2993993A2 (de) * 2013-04-26 2016-03-16 Solazyme, Inc. Öle mit niedrigem gehalt an mehrfach ungesättigten fettsäuren und verwendungen davon
FR3009619B1 (fr) 2013-08-07 2017-12-29 Roquette Freres Compositions de biomasse de microalgues riches en proteines de qualite sensorielle optimisee
CA2925527A1 (en) 2013-10-04 2015-04-09 Solazyme, Inc. Tailored oils
US9969990B2 (en) 2014-07-10 2018-05-15 Corbion Biotech, Inc. Ketoacyl ACP synthase genes and uses thereof
AR104042A1 (es) 2015-03-26 2017-06-21 Mara Renewables Corp Producción de alta densidad de biomasa y aceite utilizando glicerol en bruto
AU2016293487B2 (en) 2015-07-13 2021-07-01 MARA Renewables Corporation Enhancing microalgal metabolism of xylose
US10851395B2 (en) 2016-06-10 2020-12-01 MARA Renewables Corporation Method of making lipids with improved cold flow properties
EP4626260A2 (de) 2022-12-02 2025-10-08 DSM IP Assets B.V. Fermentativ hergestellte retinoidhaltige zusammensetzungen und verfahren zu ihrer herstellung und verwendung

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1342098A (en) * 1971-03-12 1973-12-25 Atomic Energy Authority Uk 14c-labelled compounds
US4485173A (en) * 1981-01-19 1984-11-27 Cpc International Inc. Preparation of fats and oils
JPS62146597A (ja) * 1985-12-20 1987-06-30 Idemitsu Petrochem Co Ltd 菌体中の油脂成分の分離方法
JPH0763381B2 (ja) * 1987-03-06 1995-07-12 財団法人相模中央化学研究所 微生物によるエイコサペンタエン酸含有脂質の製法
JPS63273484A (ja) * 1987-04-30 1988-11-10 Yoshihara Seiyu Kk 高パルミトオレイン酸含有脂質の製造方法
JPS63295527A (ja) * 1987-05-27 1988-12-01 Nippon Oil & Fats Co Ltd 高度不飽和脂肪酸の濃縮分離方法
GB8715428D0 (en) * 1987-07-01 1987-08-26 Univ Dundee Organic compounds
WO1989000606A1 (en) * 1987-07-20 1989-01-26 Maricultura, Incorporated Microorganism production of omega-3 (n-3) lipids
JPH0225447A (ja) * 1988-07-13 1990-01-26 Nippon Oil & Fats Co Ltd 高度不飽和脂肪酸類の製造方法
JPH02146597A (ja) * 1988-11-28 1990-06-05 Yamaha Corp 電子楽器の楽音制御方法
JP2834251B2 (ja) * 1990-01-22 1998-12-09 旭化成工業株式会社 コンクリート板用吊込み治具
JPH03273484A (ja) * 1990-03-23 1991-12-04 Sanyo Electric Co Ltd 自動販売機

Also Published As

Publication number Publication date
DE69125373T2 (de) 1997-09-25
EP0533775A1 (de) 1993-03-31
CA2083041C (en) 2003-07-22
CA2083041A1 (en) 1991-11-22
US5164308A (en) 1992-11-17
US5466434A (en) 1995-11-14
US5376540A (en) 1994-12-27
WO1991018105A1 (en) 1991-11-28
DE69125373D1 (de) 1997-04-30
JPH05507275A (ja) 1993-10-21
EP0533775A4 (en) 1993-06-30
EP0533775B1 (de) 1997-03-26

Similar Documents

Publication Publication Date Title
ATE150793T1 (de) Markierte verbindungen zur verwendung in einem diagnostischen atemtest
DE69123880D1 (de) Verfahren zur Herstellung von Eicosapentaensäure oder von einem Esterderivat davon
DE3854080D1 (de) Verfahren zur Herstellung von Bis-homo-gamma-linolensäure.
ATE11057T1 (de) Verfahren zur herstellung von d-glucoson und dfructose.
DK155800C (da) Fremgangsmaade til fremstilling af biomasse faestnet til en baerer
DE69230495D1 (de) Spurenelementreiches zusatzmittel, verfahren zu dessen herstellung, diese enthaltende zusammensetzung und deren verwendung
ES440263A1 (es) Procedimiento para la fermentacion continua de cultivos.
ATE32349T1 (de) Verfahren zur biotechnologischen herstellung von poly-d(-)-3-hydroxybuttersaeure.
IL74552A0 (en) Strains of micro-organisms able to produce l-carnitine and process for the microbiological production of l-carnitine
DE3854948D1 (de) Verfahren zur Herstellung von organobimetallischen Verbindungen
DE3781555D1 (de) Verfahren zur herstellung einer zwei diastereoisomerische n-acylaminosaeureester enthaltenden diastereoisomerischen mischung.
DE69112716D1 (de) Verfahren zur biologischen Herstellung einer Hydroxyvitamin-D-Verbindung.
DE69416424D1 (de) Verfahren zur herstellung von tert-leucin und analoge in enantiemerer form und zwischenprodukte
ATE86666T1 (de) Verfahren zur herstellung von l-sorbose und vorrichtung zur kultivierung von mikroorganismen.
ATE124449T1 (de) Mikrobiologisches verfahren zur herstellung von hydroxylierten heterocyclen.
DE69321767D1 (de) Verfahren zur Herstellung von N-Alkyl oder N-Cycloalkyl-2-Benzolthiazolesulfenimiden
SE7909905L (sv) Substratplattor for vextkulturer med forbettrad rotbildning
ATE233267T1 (de) Verfahren zur herstellung von 3- vinylcephalosporinen
ES446012A1 (es) Un procedimiento mejorado para producir microorganismos uti-lizadores de metano que son cepas de methylococcus.
ATE95568T1 (de) Mikrobiologisches verfahren zur herstellung von uk-61.689 und mikroorganismen zur verwendung darin.
JPS5763086A (en) Production of lipase
ATE3878T1 (de) Verfahren zur herstellung von 11-betahydroxysteroiden.
ATE2339T1 (de) Verfahren zur herstellung von sphingomyelinase, sphingomyelinase und deren verwendung.
DE69528225D1 (de) Verfahren zur Herstellung von Gamma-Nonalaktonen in natürlicher Form
Kyle Method of diagnosing fatty acid metabolism or absorption disorders using labeled triglyceride oils produced by cultivation of microorganisms

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties