ATE151883T1 - Verfahren zum nachweis freier igf-i, igf-ii, und gh spiegel in körperflüssigkeiten - Google Patents

Verfahren zum nachweis freier igf-i, igf-ii, und gh spiegel in körperflüssigkeiten

Info

Publication number
ATE151883T1
ATE151883T1 AT92300306T AT92300306T ATE151883T1 AT E151883 T1 ATE151883 T1 AT E151883T1 AT 92300306 T AT92300306 T AT 92300306T AT 92300306 T AT92300306 T AT 92300306T AT E151883 T1 ATE151883 T1 AT E151883T1
Authority
AT
Austria
Prior art keywords
igf
body fluid
levels
free
capture reagent
Prior art date
Application number
AT92300306T
Other languages
English (en)
Inventor
Venkat R Mukku
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ATE151883T1 publication Critical patent/ATE151883T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575—Hormones
    • G01N2333/61—Growth hormones [GH] (Somatotropin)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575—Hormones
    • G01N2333/65—Insulin-like growth factors (Somatomedins), e.g. IGF-1, IGF-2
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y10S436/817—Steroids or hormones

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Endocrinology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT92300306T 1991-01-17 1992-01-14 Verfahren zum nachweis freier igf-i, igf-ii, und gh spiegel in körperflüssigkeiten ATE151883T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/642,509 US5198340A (en) 1991-01-17 1991-01-17 Assay for free igf-i, igf-ii, and gh levels in body fluids

Publications (1)

Publication Number Publication Date
ATE151883T1 true ATE151883T1 (de) 1997-05-15

Family

ID=24576872

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92300306T ATE151883T1 (de) 1991-01-17 1992-01-14 Verfahren zum nachweis freier igf-i, igf-ii, und gh spiegel in körperflüssigkeiten

Country Status (7)

Country Link
US (1) US5198340A (de)
EP (1) EP0495625B1 (de)
AT (1) ATE151883T1 (de)
DE (1) DE69218981T2 (de)
DK (1) DK0495625T3 (de)
ES (1) ES2101802T3 (de)
GR (1) GR3024052T3 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4228839A1 (de) 1992-08-29 1994-03-03 Behringwerke Ag Verfahren zum Nachweis und zur Bestimmung von Mediatoren
DE69428454T2 (de) * 1993-12-20 2002-05-02 David Jeston Baylink Verfahren zur freisetzung bindender proteine von liganden
US6346510B1 (en) * 1995-10-23 2002-02-12 The Children's Medical Center Corporation Therapeutic antiangiogenic endostatin compositions
US5747273A (en) * 1996-05-07 1998-05-05 Diagnostic Systems Laboratories, Inc. Immunoassay of total insulin-like growth factor binding protein-1
US6066464A (en) * 1996-12-10 2000-05-23 Diagnostic Systems Laboratories, Inc. Immunoassay of IGF family of peptides, their binding proteins and related molecules in dried whole blood filter paper spots
US5824467A (en) * 1997-02-25 1998-10-20 Celtrix Pharmaceuticals Methods for predicting drug response
US6200762B1 (en) 1997-08-01 2001-03-13 Aurora Biosciences Corporation Photon reducing agents and compositions for fluorescence assays
US6214563B1 (en) 1997-08-01 2001-04-10 Aurora Biosciences Corporation Photon reducing agents for reducing undesired light emission in assays
US6221612B1 (en) * 1997-08-01 2001-04-24 Aurora Biosciences Corporation Photon reducing agents for use in fluorescence assays
US6394952B1 (en) * 1998-02-03 2002-05-28 Adeza Biomedical Corporation Point of care diagnostic systems
EP1506286B1 (de) * 2002-05-24 2014-03-19 Merck Sharp & Dohme Corp. Neutralisierung eines menschlichen anti-igfr-antikörpers
JP5179011B2 (ja) * 2002-10-09 2013-04-10 ディーエムアイ バイオサイエンシズ インコーポレイテッド 胎盤虚血および多臓器不全のモニタリング
EP2274978B1 (de) 2003-09-12 2015-05-20 Tercica, Inc. Verfahren zur Behandlung von IGF-1 (insulin-like growth factor 1)-Mangel
US7326567B2 (en) 2003-11-12 2008-02-05 Schering Corporation Plasmid system for multigene expression
US7169560B2 (en) * 2003-11-12 2007-01-30 Helicos Biosciences Corporation Short cycle methods for sequencing polynucleotides
TW200526684A (en) * 2003-11-21 2005-08-16 Schering Corp Anti-IGFR1 antibody therapeutic combinations
JP2008514900A (ja) * 2004-07-30 2008-05-08 アデザ・バイオメデイカル・コーポレイシヨン 疾病および他の状態のマーカーとしての癌胎児性フィブロネクチンならびに癌胎児性フィブロネクチンの検出のための方法
US7833513B2 (en) 2004-12-03 2010-11-16 Rhode Island Hospital Treatment of Alzheimer's Disease
PT1828249E (pt) * 2004-12-03 2011-02-25 Schering Corp Biomarcadores para a pré-selecção de pacientes para terapêutica anti-igf1r
WO2006094185A2 (en) * 2005-03-03 2006-09-08 Dmi Biosciences Inc. Quantification of proteins
JP4875064B2 (ja) * 2005-04-15 2012-02-15 シェーリング コーポレイション 癌を処置または予防するための方法および組成物
NZ564098A (en) * 2005-06-15 2010-04-30 Schering Corp Anti-IGF1R antibody formulations
CN114544978A (zh) * 2022-03-04 2022-05-27 美康生物科技股份有限公司 一种igf-1检测试剂盒及其制备方法和检测方法
CN116087386A (zh) * 2023-04-11 2023-05-09 西湖欧米(杭州)生物科技有限公司 一种人胰岛素样生长因子检测方法及试剂盒

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4005187A (en) * 1974-06-03 1977-01-25 Data Diagnostic Corporation Diagnostic test method
US4015939A (en) * 1976-05-12 1977-04-05 Bio-Rad Laboratories, Inc. Competitive binding thyroid assay with improved bound-free separation step
AT357272B (de) * 1976-09-18 1980-06-25 Boehringer Mannheim Gmbh Verfahren und vorrichtung zum nachweis und zur bestimmung eines spezifischen bindeproteins oder einer damit bindefaehigen substanz
US4219335A (en) * 1978-09-18 1980-08-26 E. I. Du Pont De Nemours And Company Immunochemical testing using tagged reagents
NZ190452A (en) * 1978-05-19 1981-04-24 Becton Dickinson Co Solid phase assay receptor contacted with analyte and then with labeled analyte
US4292296A (en) * 1978-09-12 1981-09-29 Baxter Travenol Laboratories, Inc. Diagnostic method
US4333918A (en) * 1979-03-23 1982-06-08 Technicon Instruments Corporation Radioassay for vitamin B12
US4299916A (en) * 1979-12-26 1981-11-10 Syva Company Preferential signal production on a surface in immunoassays
US4786606A (en) * 1981-01-23 1988-11-22 Baxter Travenol Laboratories, Inc. Solid phase system for ligand assay
US4477578A (en) * 1982-03-04 1984-10-16 Medical & Scientific, Inc. Method and apparatus for performing assays
US4504585A (en) * 1982-04-05 1985-03-12 Aalto Scientific, Ltd. Affinity immunoassay system
US4469787A (en) * 1982-05-14 1984-09-04 Mallinckrodt Inc. Immunoassay involving soluble complex of second antibody and labeled binding protein
JPS604423A (ja) * 1983-06-22 1985-01-10 Yamaha Motor Co Ltd 小型４輪車
US4594327A (en) * 1983-11-02 1986-06-10 Syntex (U.S.A.) Inc. Assay method for whole blood samples
GB8404843D0 (en) * 1984-02-24 1984-03-28 Amersham Int Plc Free analyte assay
EP0165669A1 (de) * 1984-05-04 1985-12-27 Corning Glass Works Methode zur Messung freien Ligands
US4791068A (en) * 1984-06-22 1988-12-13 Scripps Clinic And Research Foundation Diagnostic assay for inhibitor of tissue-type and urokinase-type plasminogen activators
FI852545A7 (fi) * 1984-06-29 1985-12-30 Ortho Diagnostic Systems Inc Vasta-aine-lektiini kerrosanalyysi.
US4680275A (en) * 1985-02-11 1987-07-14 Becton, Dickinson And Company Homogeneous fluorescence immunoassay using a light absorbing material
US4818687A (en) * 1985-02-28 1989-04-04 Massachusetts Institute Of Technology Affinity column and process for detection of low molecular weight toxic substances
US4704355A (en) * 1985-03-27 1987-11-03 New Horizons Diagnostics Corporation Assay utilizing ATP encapsulated within liposome particles
US4737456A (en) * 1985-05-09 1988-04-12 Syntex (U.S.A.) Inc. Reducing interference in ligand-receptor binding assays
GB8522388D0 (en) * 1985-09-10 1985-10-16 Lepetit Spa Receptor-antibody sandwich assay
EP0218309B1 (de) * 1985-10-04 1995-11-15 Diagnostic Products Corporation Verfahren zum Messen von Freiliganden in biologischen Flüssigkeiten
JPS6298260A (ja) * 1985-10-25 1987-05-07 Nitto Electric Ind Co Ltd 免疫活性物質測定キツト
GB2203836B (en) * 1987-04-24 1991-01-23 Dr Ch Ng Soo Ling Determination of analyte concentration by re-equilibration
AU1232188A (en) * 1987-05-29 1988-12-01 Mallinckrodt, Inc. Novel pair of monoclonal antibodies to insulin-like growth factor i permits immunometric assay for igf-i
US4943522A (en) * 1987-06-01 1990-07-24 Quidel Lateral flow, non-bibulous membrane assay protocols
US5057417A (en) * 1987-06-12 1991-10-15 Genentech, Inc. Compositions and methods for the synthesis of growth hormone receptor and growth hormone binding protein
GB2207245A (en) * 1987-07-15 1989-01-25 Unilever Plc Specific binding chemiluminescent assay
CA1305664C (en) * 1987-08-06 1992-07-28 Stephen James Lovell System and process for a visible assay for analyte
US4956302A (en) * 1987-09-11 1990-09-11 Abbott Laboratories Lateral flow chromatographic binding assay device
JPH0198969A (ja) * 1987-10-12 1989-04-17 Meiji Milk Prod Co Ltd レセプターの新規な結合測定方法
DK131988A (da) * 1988-03-11 1989-09-12 Erasmus University Igf-bindingsprotein, dna-struktur, der koder for igf-bindingsproteinet og vektor indeholdende denne dna-struktur
DD276532A1 (de) * 1988-10-25 1990-02-28 Akad Wissenschaften Ddr Verfahren zum nachweis von menschlichem wachstumshormon (hgh)
IL92816A0 (en) * 1988-12-22 1990-09-17 Biogrowth Inc Recombinant dna molecules,hosts,processes and human somatomedin carrier protein-like polypeptides
WO1990008957A1 (en) * 1989-01-30 1990-08-09 Epitope, Inc. Avidin-biotin assisted immunoassay

Also Published As

Publication number Publication date
ES2101802T3 (es) 1997-07-16
EP0495625A3 (en) 1993-04-07
DE69218981D1 (de) 1997-05-22
EP0495625A2 (de) 1992-07-22
US5198340A (en) 1993-03-30
DE69218981T2 (de) 1997-09-25
DK0495625T3 (da) 1997-10-06
GR3024052T3 (en) 1997-10-31
EP0495625B1 (de) 1997-04-16

Similar Documents

Publication Publication Date Title
ATE151883T1 (de) Verfahren zum nachweis freier igf-i, igf-ii, und gh spiegel in körperflüssigkeiten
ATE297950T1 (de) Testverfahren und reagenzien zur quantifizierung von hbnp
DE3852996D1 (de) Immunoassayverfahren zum Nachweis von Antigenen.
DE69328622D1 (de) Reagenzien und verfahren zum nachweis und zur quantifizierung von thyroxin in flüssigen proben
ATE209356T1 (de) Ein verfahren zur bestimmung von kollagenfragmenten in körperflüssigkeiten, ein testkit und mittel zur durchführung des verfahrens, und seine verwendung zur feststellung von mit dem kollagenmetabolismus assoziierten störungen
DE19882221T1 (de) Verfahren und Vorrichtung zum automatischen Impfen von Kulturmedien mit bakteriellen Proben aus klinischen Probenbehältern
ATE253645T1 (de) Verfahren zur bestimmung von säugetier nukleinsäuren aus stuhlproben und dafür benötigte reagenzien
SE9604575D0 (sv) Method and system for analyte determination
DE59309900D1 (de) Verfahren zur Analyse partikelverstärkter Agglutinationsreaktionen auf Zentrifugalanalysatoren durch Bestimmung der Trübungsaufhellung
DE60312513D1 (de) Zusammensetzungen und verfahren zum nachweis vom apo-b48 und apo-b100
ATE77149T1 (de) Verfahren und testkit zur bestimmung freier wirkstoffe in biologischen fluessigkeiten.
EP0753743A3 (de) Vitamin-D-Bestimmung
ATE111533T1 (de) Verfahren zur bestimmung von nukleinsäuren.
DE60031204D1 (de) VERFAHREN und KIT ZUM NACHWEIS UND ZUR IDENTIFIZIERUNG VON KRISTALLEN IN BIOLOGISCHEN FLÜSSIGKEITEN
DE68924243D1 (de) Verfahren und Reagenzien zum Nachweis von Amphetamin und/oder d-Methamphetamin in biologischen Proben.
EP1780537A4 (de) Proteomanalyseverfahren für phosphoryliertes protein
ATE206522T1 (de) Massensensitive biosensoren
EP1138781A3 (de) Methode zur Quantifizierung der Bindeaktivität von DNA-bindenden Proteinen
ATE462975T1 (de) Verfahren zum immunochemischen testen des anti- hm1.24-antikörpers
ATE121197T1 (de) Immunometrisches verfahren zum nachweis von lipoprotein-teilchen, anti-lp(a) monoklonale antikörper und ihre anwendung zur diagnose von atherosklerose.
CA2366651A1 (en) A method for detecting megsin protein and use thereof
IL79283A (en) Method for determining free ligands in biological fluids with protein bound ligands,by using an analogue tracer specific lig-and binder and chemical inhibitor
DE69930843D1 (de) Verfahren zum bestimmen von autoantikörpern
DE69935850D1 (de) Verfahren zur messung der gesamkonzentration eines analytes
FR2805545B1 (fr) Procede electrochimique de detection d'acides nucleiques

Legal Events

Date Code Title Description
EELA Cancelled due to lapse of time