ATE209356T1 - Ein verfahren zur bestimmung von kollagenfragmenten in körperflüssigkeiten, ein testkit und mittel zur durchführung des verfahrens, und seine verwendung zur feststellung von mit dem kollagenmetabolismus assoziierten störungen - Google Patents

Ein verfahren zur bestimmung von kollagenfragmenten in körperflüssigkeiten, ein testkit und mittel zur durchführung des verfahrens, und seine verwendung zur feststellung von mit dem kollagenmetabolismus assoziierten störungen

Info

Publication number
ATE209356T1
ATE209356T1 AT94926817T AT94926817T ATE209356T1 AT E209356 T1 ATE209356 T1 AT E209356T1 AT 94926817 T AT94926817 T AT 94926817T AT 94926817 T AT94926817 T AT 94926817T AT E209356 T1 ATE209356 T1 AT E209356T1
Authority
AT
Austria
Prior art keywords
collagen
fragments
carrying
test kit
body fluid
Prior art date
Application number
AT94926817T
Other languages
English (en)
Inventor
Per Qvist
Martin Bonde
Original Assignee
Osteometer Biotech As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8100323&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE209356(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Osteometer Biotech As filed Critical Osteometer Biotech As
Application granted granted Critical
Publication of ATE209356T1 publication Critical patent/ATE209356T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders
    • G01N2800/108—Osteoporosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT94926817T 1993-09-17 1994-09-19 Ein verfahren zur bestimmung von kollagenfragmenten in körperflüssigkeiten, ein testkit und mittel zur durchführung des verfahrens, und seine verwendung zur feststellung von mit dem kollagenmetabolismus assoziierten störungen ATE209356T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK931040A DK104093D0 (da) 1993-09-17 1993-09-17 Fremgangsmaade til bestemmelse af collagen-fragmenter i legemsvaesker, test-kit og midler til udoevelse af fremgangsmaaden og anvendelse af fremgangsmaaden til diagnosticering af lidelser associeret til collagen-metabolismen
PCT/DK1994/000348 WO1995008115A1 (en) 1993-09-17 1994-09-19 A method of assaying collagen fragments in body fluids, a test kit and means for carrying out the method and use of the method to diagnose the presence of disorders associated with the metabolism of collagen

Publications (1)

Publication Number Publication Date
ATE209356T1 true ATE209356T1 (de) 2001-12-15

Family

ID=8100323

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94926817T ATE209356T1 (de) 1993-09-17 1994-09-19 Ein verfahren zur bestimmung von kollagenfragmenten in körperflüssigkeiten, ein testkit und mittel zur durchführung des verfahrens, und seine verwendung zur feststellung von mit dem kollagenmetabolismus assoziierten störungen

Country Status (7)

Country Link
EP (2) EP0742902B2 (de)
JP (2) JP3423720B2 (de)
AT (1) ATE209356T1 (de)
AU (1) AU7652194A (de)
DE (1) DE69429192T3 (de)
DK (1) DK104093D0 (de)
WO (1) WO1995008115A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5962639A (en) * 1987-11-06 1999-10-05 Washington Research Foundation Synthetic peptides corresponding to telopeptide sequences of cross-linked type I collagen metabolites
GB9506050D0 (en) * 1995-03-24 1995-05-10 Osteometer A S Assaying collagen fragments in body fluids
AU3746295A (en) 1994-10-17 1996-05-06 Osteometer Biotech As Estimation of the fragmentation pattern of collagen in body fluids and the diagnosis of disorders associated with the metabolism of collagen
US5750647A (en) * 1995-05-19 1998-05-12 Washington Research Foundation Synthetic peptide analogs of NTx
US6107047A (en) * 1996-03-21 2000-08-22 Osteometer Biotech A/S Assaying protein fragments in body fluids
GB9617616D0 (en) * 1996-08-22 1996-10-02 Osteometer Biotech As Assaying protein fragments in body fluids
EP0829724A1 (de) * 1996-09-17 1998-03-18 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Verfahren zum Nachweis von Kollagenabbau
JP3913787B2 (ja) * 1996-12-09 2007-05-09 オステオメーター・ビオテク・エー／エス Ｉ型コラーゲン断片のサンドウイッチ測定法
JPH10300749A (ja) * 1997-04-28 1998-11-13 Mitsubishi Chem Corp コラーゲン断片を認識する抗体
WO1999006840A1 (en) * 1997-07-31 1999-02-11 Metra Biosystems, Inc. Collagen-peptide assay method
AU9312598A (en) * 1997-09-10 1999-03-29 Allegheny University Of The Health Sciences Inhibitors of collagen assembly
US6117646A (en) * 1997-09-22 2000-09-12 Osteometer Biotech A/S Assaying protein fragments in body fluids
US6602980B1 (en) 1998-06-19 2003-08-05 Washington Research Foundation Collagen type III synthetic peptides for collagen resorption assays
US6348320B1 (en) 1998-06-19 2002-02-19 Washington Research Foundation Cartilage resorption assays measuring type II collagen fragments
US6916903B2 (en) 1998-06-19 2005-07-12 Washington Research Foundation Collagen type III synthetic peptides for collagen resorption assays
DE19980834T1 (de) 1998-06-19 2001-06-13 Washington Res Found Knorpel-Resorptionstests
DE19919982C2 (de) * 1999-04-30 2001-06-28 Pe Diagnostik Gmbh Verfahren zur Ermittlung osteoporotischer Prozesse
DE69920981T2 (de) * 1999-06-17 2005-07-21 Washington Research Foundation, Seattle Knorpelresorptionsassays
JP2003002845A (ja) * 2001-04-03 2003-01-08 Univ Nihon 哺乳類の硬組織治療用組成物及びその治療方法
RU2357974C2 (ru) * 2003-01-10 2009-06-10 Аблинкс Н.В. Терапевтические полипептиды, их гомологи, их фрагменты и их применение для модуляции агрегации, опосредованной тромбоцитами
FI20050814A0 (fi) * 2005-08-11 2005-08-11 Procollagen Oy Menetelmä nivelreumassa muodostuvien kollageeniautovasta-aineiden havaitsemiseksi
DK2538222T3 (da) * 2007-11-05 2021-11-15 Nordic Bioscience As Biokemiske markører til cvd-risikovurdering
DE102010037622B4 (de) 2010-09-17 2012-07-12 Lophius Biosciences Gmbh Verfahren zum Nachweis, Differenzieren und Quantifizieren von T-Zellpopulationen mittels der Reverse Transkription quantitativen Real-Time PCR (RT-qPCR) Technologie
GB201016050D0 (en) * 2010-09-24 2010-11-10 Nordic Bioscience As Assay for a type II collagen biomarker in serum
EP2822457A4 (de) * 2012-03-09 2015-11-11 Basf Se Mittel und verfahren zur beurteilung von schilddrüsenüberfunktion
JP7341774B2 (ja) * 2019-07-30 2023-09-11 オリエンタル酵母工業株式会社 骨質の評価方法
WO2023068248A1 (ja) * 2021-10-20 2023-04-27 積水メディカル株式会社 Ｉ型コラーゲン架橋ｎ－テロペプチドの免疫測定方法及び免疫測定キット、並びに抗体又はその抗体断片
US20240369543A1 (en) * 2021-10-20 2024-11-07 Sekisui Medical Co., Ltd. Measuring reagent for cross-linked n-telopeptide of type i collagen, preparation method thereof, and immunoassay method using same
CN118922717A (zh) * 2022-03-25 2024-11-08 积水医疗株式会社 免疫学检测方法和免疫学检测试剂盒
CN118829882A (zh) * 2022-03-25 2024-10-22 积水医疗株式会社 免疫学检测方法和免疫学检测试剂盒
CN116102638B (zh) * 2023-01-09 2025-05-16 中国农业科学院农产品加工研究所 基于亲和吸附富集骨胶原蛋白成骨活性肽的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3209149A1 (de) * 1982-03-13 1983-10-06 Hoechst Ag Verfahren zur gemeinsamen immunologischen bestimmung von prokollagen-peptid (typ iii) und prokollagen-peptid col 1 (typ iii) und verfahren zur herstellung von anti-prokollagen-peptid col 1 (typ iii)-serum
US5300434A (en) † 1987-11-06 1994-04-05 Washington Research Foundation Hybridoma cell line producing an antibody to type-I collagen amino-terminal telopeptide
US4973666A (en) * 1987-11-06 1990-11-27 Washington Research Foundation Peptide fragments containing HP and LP cross-links
GB9105893D0 (en) * 1991-03-20 1991-05-08 Orion Yhtymae Oy Bone resorption assay based on a peptide liberated during collagen degradation
EP0631586B1 (de) * 1992-01-31 1997-12-29 David Jeston Baylink Aminoterminale prokollagen 1(i) peptide
DE4225038C2 (de) * 1992-07-29 1995-11-30 Boehringer Mannheim Gmbh Herstellung und Verwendung von Antikörpern gegen Kollagen
JPH08505149A (ja) * 1992-12-28 1996-06-04 ジェイ． ベイリンク，デビッド 骨再吸収検定法
US5750647A (en) * 1995-05-19 1998-05-12 Washington Research Foundation Synthetic peptide analogs of NTx

Also Published As

Publication number Publication date
DK104093D0 (da) 1993-09-17
EP1104887A2 (de) 2001-06-06
JP3790727B2 (ja) 2006-06-28
DE69429192T2 (de) 2002-07-18
WO1995008115A1 (en) 1995-03-23
EP0742902B1 (de) 2001-11-21
EP0742902B2 (de) 2007-06-13
JP3423720B2 (ja) 2003-07-07
DE69429192T3 (de) 2008-01-17
EP1104887A3 (de) 2009-08-26
DE69429192D1 (de) 2002-01-03
AU7652194A (en) 1995-04-03
JPH09509736A (ja) 1997-09-30
EP0742902A1 (de) 1996-11-20
JP2003202338A (ja) 2003-07-18

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