ATE152127T1 - Muteine des menschlichen parathormons und ihre herstellung - Google Patents

Muteine des menschlichen parathormons und ihre herstellung

Info

Publication number
ATE152127T1
ATE152127T1 AT92113322T AT92113322T ATE152127T1 AT E152127 T1 ATE152127 T1 AT E152127T1 AT 92113322 T AT92113322 T AT 92113322T AT 92113322 T AT92113322 T AT 92113322T AT E152127 T1 ATE152127 T1 AT E152127T1
Authority
AT
Austria
Prior art keywords
amino acid
recombinant dna
human parathyroid
residue
parathyroid hormone
Prior art date
Application number
AT92113322T
Other languages
English (en)
Inventor
Tsunehiko Fukuda
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP4169713A external-priority patent/JPH05271279A/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ATE152127T1 publication Critical patent/ATE152127T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C07K2319/41—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a Myc-tag
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/735—Fusion polypeptide containing domain for protein-protein interaction containing a domain for self-assembly, e.g. a viral coat protein (includes phage display)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT92113322T 1991-08-07 1992-08-05 Muteine des menschlichen parathormons und ihre herstellung ATE152127T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP19805691 1991-08-07
JP4169713A JPH05271279A (ja) 1991-08-07 1992-06-26 ヒト副甲状腺ホルモンムテインおよびその製造法

Publications (1)

Publication Number Publication Date
ATE152127T1 true ATE152127T1 (de) 1997-05-15

Family

ID=26492969

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92113322T ATE152127T1 (de) 1991-08-07 1992-08-05 Muteine des menschlichen parathormons und ihre herstellung

Country Status (4)

Country Link
EP (1) EP0528271B1 (de)
AT (1) ATE152127T1 (de)
CA (1) CA2075408A1 (de)
DE (1) DE69219242T2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996017941A2 (en) * 1994-12-07 1996-06-13 Bionebraska, Inc. Production of c-terminal amidated peptides from recombinant protein constructs
CA2178894A1 (en) * 1995-06-15 1996-12-16 Tsunehiko Fukuda Parathyroid hormone derivatives and their use
AU3161997A (en) * 1996-06-21 1998-01-14 Francis Gossard A novel hypertension related calcium regulated gene (hcarg)
WO2016065052A1 (en) 2014-10-22 2016-04-28 Extend Biosciences, Inc. Insulin vitamin d conjugates
US9585934B2 (en) * 2014-10-22 2017-03-07 Extend Biosciences, Inc. Therapeutic vitamin D conjugates

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3312928A1 (de) * 1983-04-11 1984-11-22 Gesellschaft für Biotechnologische Forschung mbH (GBF), 3300 Braunschweig Human-parathormon produzierende hybridvektoren und human-parathormongen
EP0383751B1 (de) * 1986-10-22 1994-03-09 GAUTVIK, Kaare M., Dr. Herstellung von human-parathyroidhormon
EP0341963A3 (de) * 1988-05-09 1991-07-24 Merck & Co. Inc. Parathyroidhormonhemmer
US5171670A (en) * 1989-05-12 1992-12-15 The General Hospital Corporation Recombinant dna method for production of parathyroid hormone
CA2040264A1 (en) * 1990-04-12 1991-10-13 Tatsuhiko Kanmera Parathyroid hormone antagonists

Also Published As

Publication number Publication date
EP0528271B1 (de) 1997-04-23
DE69219242D1 (de) 1997-05-28
EP0528271A1 (de) 1993-02-24
CA2075408A1 (en) 1993-02-08
DE69219242T2 (de) 1997-09-25

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties