ATE152181T1 - Methode zum nachweis von unweltbedingten vergehen - Google Patents

Methode zum nachweis von unweltbedingten vergehen

Info

Publication number
ATE152181T1
ATE152181T1 AT94903321T AT94903321T ATE152181T1 AT E152181 T1 ATE152181 T1 AT E152181T1 AT 94903321 T AT94903321 T AT 94903321T AT 94903321 T AT94903321 T AT 94903321T AT E152181 T1 ATE152181 T1 AT E152181T1
Authority
AT
Austria
Prior art keywords
pct
stress
environmental stress
sec
unenvironmental
Prior art date
Application number
AT94903321T
Other languages
English (en)
Inventor
Robert Alan Larossa
William Robert Majarian
Dyk Tina Kangas Van
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26743124&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE152181(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Du Pont filed Critical Du Pont
Application granted granted Critical
Publication of ATE152181T1 publication Critical patent/ATE152181T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0069—Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/66—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving luciferase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Enzymes And Modification Thereof (AREA)
AT94903321T 1992-12-04 1993-12-02 Methode zum nachweis von unweltbedingten vergehen ATE152181T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98842892A 1992-12-04 1992-12-04
US6317393A 1993-05-14 1993-05-14

Publications (1)

Publication Number Publication Date
ATE152181T1 true ATE152181T1 (de) 1997-05-15

Family

ID=26743124

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94903321T ATE152181T1 (de) 1992-12-04 1993-12-02 Methode zum nachweis von unweltbedingten vergehen

Country Status (11)

Country Link
US (1) US5683868A (de)
EP (1) EP0673439B2 (de)
JP (1) JPH08504101A (de)
KR (1) KR100262681B1 (de)
AT (1) ATE152181T1 (de)
AU (1) AU5730494A (de)
CA (1) CA2150232C (de)
DE (1) DE69310207T3 (de)
ES (1) ES2102811T5 (de)
IL (2) IL107815A (de)
WO (1) WO1994013831A1 (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2200702C (en) * 1994-11-23 2000-12-05 E.I. Du Pont De Nemours And Company Lyophilized bioluminescent bacterial reagent for the detection of toxicants
AU724155B2 (en) * 1996-04-25 2000-09-14 Vlaamse Instelling Voor Technologisch Onderzoek (Vito) Recombinant nucleic acid sequences and methods for determining both genotoxicity and mutagenicity of a sample and the kinetics of the genetoxicity
US5817463A (en) * 1996-06-28 1998-10-06 Abbott Laboratories Nucleic acid primers and probes for detecting Mycoplasma pneumoniae
AUPO128096A0 (en) * 1996-07-29 1996-08-22 Crc For Waste Management And Pollution Control Limited Biosensors
US6025131A (en) * 1996-10-23 2000-02-15 E. I. Du Pont De Namours And Company Facile method for identifying regulated promoters
EP0943000A1 (de) * 1996-11-15 1999-09-22 E.I. Du Pont De Nemours And Company Hochsensitive methode zum nachweis von schädlichen umwelteinflüssen unter verwendung kleiner probenvolumina
IL131336A0 (en) * 1997-02-28 2001-01-28 Du Pont A method for identifying the site of action of xenobiotic chemicals
GB9713666D0 (en) 1997-06-27 1997-09-03 Univ Cambridge Tech Biosensor materials and methods
WO1999014311A1 (en) * 1997-09-18 1999-03-25 Smithkline Beecham Corporation Method of screening for antimicrobial compounds
CA2321931A1 (en) * 1998-03-06 1999-09-10 E.I. Du Pont De Nemours And Company Methods for identifying polycationic, peptide-like compounds with antibacterial activity
US6703211B1 (en) * 1998-03-13 2004-03-09 Promega Corporation Cellular detection by providing high energy phosphate donor other than ADP to produce ATP
EP0950717A1 (de) 1998-04-14 1999-10-20 "VLAAMSE INSTELLING VOOR TECHNOLOGISCH ONDERZOEK", afgekort "V.I.T.O." Diagnostisches System und Verfahren zur Bestimmung genotoxischer Substanzen in einer Probe
GB9819666D0 (en) * 1998-09-09 1998-11-04 Univ Aberdeen Biosensor
US6720415B2 (en) * 1998-12-02 2004-04-13 Princeton University Compositions and methods for regulating bacterial pathogenesis
US6602666B2 (en) 1998-12-02 2003-08-05 Vlaamse Instelling Technologisch Onderzoek (V.I.T.O.) Recombinant nucleic acid sequences and methods for determining both genotoxicity and mutagenicity of a sample and the kinetics of the genotoxicity
US6677431B2 (en) 1999-12-10 2004-01-13 The Trustees Of The University Of Pennsylvania Design, preparation, and properties of antibacterial β-peptides
GB0000908D0 (en) * 2000-01-14 2000-03-08 Scient Generics Ltd Parallel free-space optical communications
KR100414784B1 (ko) * 2000-01-18 2004-01-13 (주)바이오니아 연속식 수질 독성 검사 장치
KR100377539B1 (ko) * 2000-04-06 2003-03-26 광주과학기술원 식품내 잔류하는 농약에 대한 발광미생물을 이용한 독성탐지방법
US6716582B2 (en) 2000-04-14 2004-04-06 E. I. Du Pont De Nemours And Company Cellular arrays for the identification of altered gene expression
KR20020041603A (ko) * 2000-11-28 2002-06-03 박호군 발광유전자 luxCDABE를 포함하는 재조합플라스미드, 이 플라스미드에 의해 형질 전환된 대장균SB01(KFCC 11176) 및 이의 용도
CA2365791A1 (en) 2000-12-22 2002-06-22 Pfizer Products Inc. Novel bioluminescent assays and bacterial strains useful therein
US20040076954A1 (en) * 2001-03-12 2004-04-22 Irm, Llc Genomics-driven high speed cellular assays, development thereof, and collections of cellular reporters
DE10138766A1 (de) * 2001-08-07 2003-02-20 Bayer Cropscience Ag Verfahren zum Identifizieren von makrocyclischen Polyketiden
DE10242433A1 (de) * 2002-09-11 2004-03-25 Henkel Kgaa DNA-Chips zur Bioprozeßkontrolle
WO2005017198A2 (en) * 2003-08-18 2005-02-24 Aic Surface display expression system
WO2006018049A1 (en) * 2004-08-18 2006-02-23 Aic Surface display expression system
WO2006096063A1 (en) * 2005-03-11 2006-09-14 Stichting Voor De Technische Wetenschappen Construct and method for screening, selection and identification of stress factors
KR100697245B1 (ko) 2005-03-28 2007-03-21 한국생명공학연구원 중금속 유도성 프로모터와 이의 생물공학적 활용
WO2007058807A1 (en) * 2005-11-10 2007-05-24 Chaperone Technologies, Inc. Screening method for dnak inhibitors
KR100749493B1 (ko) 2006-03-22 2007-08-14 한국원자력연구원 대장균에서 rpoS 유전자의 발현을 조절함으로서프로피온산에 대한 미생물 감수성을 증진시키는 방법
RU2348687C1 (ru) * 2007-05-21 2009-03-10 Институт цитологии и генетики Сибирского отделения Российской академии наук (СО РАН) Штамм бактерий escherichia coli для тестирования присутствия в среде фенола и перекиси водорода
RU2355760C1 (ru) * 2007-10-29 2009-05-20 Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов" (ФГУП ГосНИИгенетика) НАБОР lux-БИОСЕНСОРОВ ДЛЯ ОПРЕДЕЛЕНИЯ ДЕТЕРГЕНТОВ ГИДРОФОБНОЙ ПРИРОДЫ В СРЕДЕ
US8647642B2 (en) 2008-09-18 2014-02-11 Aviex Technologies, Llc Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment
WO2013052237A2 (en) * 2011-09-08 2013-04-11 Attagene, Inc. Systems and methods for assay of bio-contaminants in water
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4581335A (en) * 1982-12-01 1986-04-08 Texas A&M University System Process for producing a cloned luciferase-synthesizing microorganism
US5221623A (en) * 1986-07-22 1993-06-22 Boyce Thompson Institute For Plant Research, Inc. Use of bacterial luciferase structural genes for cloning and monitoring gene expression in microorganisms and for tagging and identification of genetically engineered organisms
US5232833A (en) * 1988-09-14 1993-08-03 Stressgen Biotechnologies Corporation Accumulation of heat shock proteins for evaluating biological damage due to chronic exposure of an organism to sublethal levels of pollutants
DE3833628A1 (de) * 1988-10-03 1990-04-12 Genlux Forschungsgesellschaft Verfahren zum nachweis und zur identifikation toxischer substanzen mit hilfe klonierter mikroorganismen
DE3902982A1 (de) * 1989-02-01 1990-08-02 Genlux Forschungsgesellschaft Verfahren zum nachweis von quecksilber mit hilfe von durch quecksilber zu erhoehter biolumineszenz angeregter mikroorganismen
EP0573500B2 (de) * 1991-03-01 2002-05-02 Vito Fusionierte gene sowie deren verwendung zur bestimmung von metall- und xenobiotikagehalten
EP0597984A1 (de) * 1991-07-30 1994-05-25 Bio-Technical Resources, Inc. Einrichtung für das aufspüren von wässrigen unreinheiten
CA2139667C (en) * 1992-07-06 2005-03-29 Spencer B. Farr Methods and diagnostic kits for determining toxicity utilizing bacterial stress promoters fused to reporter genes

Also Published As

Publication number Publication date
ES2102811T5 (es) 2001-10-16
EP0673439A1 (de) 1995-09-27
JPH08504101A (ja) 1996-05-07
DE69310207T2 (de) 1997-08-14
IL107815A (en) 2003-12-10
IL107815A0 (en) 1994-04-12
DE69310207T3 (de) 2001-11-15
IL139794A0 (en) 2002-02-10
WO1994013831A1 (en) 1994-06-23
DE69310207D1 (de) 1997-05-28
CA2150232C (en) 2000-12-19
KR950704511A (ko) 1995-11-20
EP0673439B1 (de) 1997-04-23
AU5730494A (en) 1994-07-04
EP0673439B2 (de) 2001-07-04
CA2150232A1 (en) 1994-06-23
ES2102811T3 (es) 1997-08-01
US5683868A (en) 1997-11-04
KR100262681B1 (ko) 2000-08-01

Similar Documents

Publication Publication Date Title
DE69310207D1 (de) Methode zum Nachweis von unweltbedingten Vergehen
ATE316147T1 (de) Enzymsensor
CA2320159A1 (en) A system for pathfinding
ATE147790T1 (de) Direkte methode zum nachweis von sehr niedrigerem grad der coliform-kontamination
IL158743A0 (en) Polynucleotide sequencing method
FI102618B1 (fi) Menetelmä proteiini-inhibiittorien ja -aktivaattorien seulomiseksi
DK0711360T3 (da) Fremgangsmåde til identificering af mikroorganismer under anvendelse af mindst to kromogener
DK0823041T3 (da) Fremgangsmåde til farvedetektering
SE8801702D0 (sv) Sett vid bestemning av enzymatisk aktivitet
DE69732647D1 (de) Verfahren und kulturmedien zum nachweis von hefen und/oder schimmelpilzen in proben
ES2171964T3 (es) Esteres dibenzodihidropiridinecarboxilicos y su uso en metodos de ensayo quimiluminiscente.
ATE148745T1 (de) Kontrolle der mikrosporogenese durch verwendung von externinduzierbaren promotorsequenzen
ATE399860T1 (de) Mutation innerhalb des connexin 26 gens und bezug zu prelingualer syndromloser taubheit sowie detektionsverfahren
FR2708285B1 (fr) Procédé d'identification de microorganismes avec un milieu supplémenté en hydrate de carbone.
ATE142173T1 (de) Methode zum regeln von abwasserreinigungsanlagen unter anwendung von qualitätsauswertung von messwerten
DE60026598D1 (de) Neue enzymatische substrate zum nachweis von pseudomonas aeruginosa
AU5707794A (en) Determination of toxicity
IL101996A (en) Regulation of enzyme activities by contacting them with noble gases
DE69214843D1 (de) Verfahren zum nachweis von beschädigungen des magenepithels
NZ309777A (en) Method for the detection of compounds that modulate the effects of the obese protein
ATE540966T1 (de) Von phenoxazinon abgeleitete neue enzymsubstrate und deren verwendung als entwickler bei der detektion von mikroorganismen mit peptidaseaktivität
DE69409372D1 (de) Immunoassay-verfahren mit verwendung von zeta potential
ATE193552T1 (de) Intersexuelle heterozygote phycomyces
DE69837768D1 (de) Verfahren und agens zur bestimmung von deaminase-aktivität
EP0426768A4 (en) Expression of dna sequences derived from nocardioform microorganisms