ATE152450T1 - 2,3,4,5-tetrahydro-1h-3-benzazepine und ihre pharmazeutisch verträglichen säureadditionssalze - Google Patents

2,3,4,5-tetrahydro-1h-3-benzazepine und ihre pharmazeutisch verträglichen säureadditionssalze

Info

Publication number: ATE152450T1
Authority: AT; Austria
Prior art keywords: benzazepines; tetrahydro; pharmaceutically acceptable; acid addition; addition salts
Prior art date: 1992-02-24

Application number

AT93905215T

Other languages

English (en)

Inventor

Christian Foged

Rolf Hohlweg

Erik Bardrum Nielsen

Original Assignee

Novo Nordisk As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-02-24

Filing date

1993-02-05

Publication date

1997-05-15

1993-02-05 Application filed by Novo Nordisk As filed Critical Novo Nordisk As

1997-05-15 Application granted granted Critical

1997-05-15 Publication of ATE152450T1 publication Critical patent/ATE152450T1/de

Links

239000002253 acid Substances 0.000 title 1
150000003839 salts Chemical class 0.000 title 1
MWVMYAWMFTVYED-UHFFFAOYSA-N 2,3,4,5-tetrahydro-1h-3-benzazepine Chemical class C1CNCCC2=CC=CC=C21 MWVMYAWMFTVYED-UHFFFAOYSA-N 0.000 abstract 1
210000003169 central nervous system Anatomy 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
150000002431 hydrogen Chemical class 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

AT93905215T 1992-02-24 1993-02-05 2,3,4,5-tetrahydro-1h-3-benzazepine und ihre pharmazeutisch verträglichen säureadditionssalze ATE152450T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DK92233A DK23392D0 (da)	1992-02-24	1992-02-24	Heterocykliske forbindelser, deres anvendelse og fremstilling

Publications (1)

Publication Number	Publication Date
ATE152450T1 true ATE152450T1 (de)	1997-05-15

Family

ID=8091236

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT93905215T ATE152450T1 (de)	1992-02-24	1993-02-05	2,3,4,5-tetrahydro-1h-3-benzazepine und ihre pharmazeutisch verträglichen säureadditionssalze

Country Status (23)

Country	Link
EP (1)	EP0628039B1 (de)
JP (1)	JPH07504172A (de)
KR (1)	KR100255739B1 (de)
AT (1)	ATE152450T1 (de)
AU (1)	AU667878B2 (de)
BG (1)	BG62208B1 (de)
CA (1)	CA2130678C (de)
CZ (1)	CZ288626B6 (de)
DE (1)	DE69310353T2 (de)
DK (2)	DK23392D0 (de)
ES (1)	ES2102019T3 (de)
FI (1)	FI113770B (de)
GR (1)	GR3023896T3 (de)
HU (1)	HU221314B1 (de)
IL (1)	IL104657A (de)
NO (1)	NO310193B1 (de)
NZ (1)	NZ249465A (de)
RO (1)	RO116088B1 (de)
RU (1)	RU2114839C1 (de)
SK (1)	SK281390B6 (de)
UA (1)	UA34451C2 (de)
WO (1)	WO1993017012A1 (de)
ZA (1)	ZA931099B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK0750616T3 (da) *	1994-03-16	2001-07-23	Cenes Ltd	Syreadditionssalte af 2,3,4,5-tetrahydro-1H-3-benzazapinforbindelser
HUP9900746A3 (en) *	1995-09-15	1999-11-29	Cenes Ltd Histon	Acid addition salts of 2,3,4,5-tetrahydro-1h-3-benzazepine compounds, process for their preparation and pharmaceutical compositions containing the same
GB0130576D0 (en) *	2001-12-20	2002-02-06	Cenes Ltd	Dopamine D1 receptor agonist pro-drug compounds & derivatives
ATE441417T1 (de) *	2002-12-20	2009-09-15	Glaxo Group Ltd	Benzoädüazepinderivate für die behandlung von neurologischen krankheiten
PL2912019T3 (pl)	2012-10-25	2021-11-02	Tetra Discovery Partners Llc	Heteroarylowe inhibitory pde4
WO2015048407A1 (en) *	2013-09-26	2015-04-02	Tetra Discovery Partners, LLC	Heteroaryl inhibitors of pde4

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK180485D0 (da) *	1985-04-22	1985-04-23	Novo Industri As	Nitrogenholdige forbindelser
DK325188D0 (da) *	1988-06-15	1988-06-15	Novo Industri As	Hidtil ukendte benzazepinderivater
DK67489D0 (da) *	1989-02-14	1989-02-14	Novo Industri As	Nye benzazepinderivater

1992
- 1992-02-24 DK DK92233A patent/DK23392D0/da not_active Application Discontinuation
1993
- 1993-02-05 RU RU94040719A patent/RU2114839C1/ru not_active IP Right Cessation
- 1993-02-05 EP EP93905215A patent/EP0628039B1/de not_active Expired - Lifetime
- 1993-02-05 CA CA002130678A patent/CA2130678C/en not_active Expired - Fee Related
- 1993-02-05 WO PCT/DK1993/000041 patent/WO1993017012A1/en not_active Ceased
- 1993-02-05 JP JP5514460A patent/JPH07504172A/ja active Pending
- 1993-02-05 HU HU9402434A patent/HU221314B1/hu not_active IP Right Cessation
- 1993-02-05 ES ES93905215T patent/ES2102019T3/es not_active Expired - Lifetime
- 1993-02-05 KR KR1019940702944A patent/KR100255739B1/ko not_active Expired - Fee Related
- 1993-02-05 AU AU36265/93A patent/AU667878B2/en not_active Ceased
- 1993-02-05 DK DK93905215.5T patent/DK0628039T3/da active
- 1993-02-05 DE DE69310353T patent/DE69310353T2/de not_active Expired - Fee Related
- 1993-02-05 SK SK1000-94A patent/SK281390B6/sk unknown
- 1993-02-05 NZ NZ249465A patent/NZ249465A/en unknown
- 1993-02-05 AT AT93905215T patent/ATE152450T1/de not_active IP Right Cessation
- 1993-02-05 UA UA94085741A patent/UA34451C2/uk unknown
- 1993-02-05 RO RO94-01400A patent/RO116088B1/ro unknown
- 1993-02-05 CZ CZ19941988A patent/CZ288626B6/cs not_active IP Right Cessation
- 1993-02-09 IL IL10465793A patent/IL104657A/en not_active IP Right Cessation
- 1993-02-17 ZA ZA931099A patent/ZA931099B/xx unknown
1994
- 1994-08-22 BG BG98993A patent/BG62208B1/bg unknown
- 1994-08-23 FI FI943875A patent/FI113770B/fi not_active IP Right Cessation
- 1994-08-24 NO NO19943123A patent/NO310193B1/no not_active IP Right Cessation
1997
- 1997-06-26 GR GR970401543T patent/GR3023896T3/el unknown

Also Published As

Publication number	Publication date
JPH07504172A (ja)	1995-05-11
RO116088B1 (ro)	2000-10-30
BG98993A (bg)	1995-05-31
HUT71127A (en)	1995-11-28
AU3626593A (en)	1993-09-13
KR950700286A (ko)	1995-01-16
EP0628039A1 (de)	1994-12-14
DK23392D0 (da)	1992-02-24
CZ288626B6 (cs)	2001-08-15
AU667878B2 (en)	1996-04-18
IL104657A0 (en)	1993-06-10
NO943123L (no)	1994-08-24
CZ198894A3 (en)	1995-10-18
CA2130678C (en)	2004-04-20
CA2130678A1 (en)	1993-08-25
FI943875L (fi)	1994-08-23
SK100094A3 (en)	1995-04-12
DK0628039T3 (da)	1997-12-08
FI113770B (fi)	2004-06-15
FI943875A0 (fi)	1994-08-23
HU221314B1 (en)	2002-09-28
BG62208B1 (bg)	1999-05-31
KR100255739B1 (ko)	2000-05-01
EP0628039B1 (de)	1997-05-02
ZA931099B (en)	1994-08-17
WO1993017012A1 (en)	1993-09-02
RU94040719A (ru)	1996-07-10
IL104657A (en)	1999-11-30
NZ249465A (en)	1996-02-27
SK281390B6 (sk)	2001-03-12
NO943123D0 (no)	1994-08-24
HU9402434D0 (en)	1994-10-28
GR3023896T3 (en)	1997-09-30
UA34451C2 (uk)	2001-03-15
NO310193B1 (no)	2001-06-05
DE69310353T2 (de)	1997-10-02
RU2114839C1 (ru)	1998-07-10
DE69310353D1 (de)	1997-06-05
ES2102019T3 (es)	1997-07-16

Legal Events

Date	Code	Title
1997-09-15	UEP	Publication of translation of european patent specification
2000-09-15	EEIH	Change in the person of patent owner
2005-11-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
FI941378A0 (fi)	1994-03-24	Bentsimidatsoliyhdisteitä, niiden käyttö ja valmistus
ATE211743T1 (de)	2002-01-15	Substituierte 3-aminochinuclidine
PH25571A (en)	1991-08-08	Alpha'-alkyl-4-amino-3-quinolinemethanols, 1-(4-aralkylamino-3-quinolinyl) alaknones, their use as medicaments
ATE206708T1 (de)	2001-10-15	Benzimidazolonderivate mit zentraler dopaminerger aktivität
FI970469A0 (fi)	1997-02-04	Bentsimidatsolijohdannaisia, joilla on dopaminerginen aktiivisuus
DE69310353D1 (de)	1997-06-05	2,3,4,5-tetrahydro-1h-3-benzazepine und ihre pharmazeutisch verträglichen säureadditionssalze
TW349864B (en)	1999-01-11	Use of N-(pyridinyl)-1H-indol-a-amines for the preparation of a medicament for the treatment of obsessive-compulsive disorders
FI865220A0 (fi)	1986-12-19	Foerfarande foer framstaellning av sulfinyl- och sulfonylsubstituerade 3-benzazepiner.
ATE89553T1 (de)	1993-06-15	Hydroxy-1,2,3,4-tetrahydroaminoacridine, verfahren fuer ihre herstellung und ihre verwendung als arzneimittel.