ATE152722T1 - Verfahren zur herstellung von 9-(2-hydroxy)- ethoxy-guanin - Google Patents

Verfahren zur herstellung von 9-(2-hydroxy)- ethoxy-guanin

Info

Publication number: ATE152722T1
Authority: AT; Austria
Prior art keywords: pct; guanine; ethoxy; hydroxy; producing
Prior art date: 1993-09-10

Application number

AT94906897T

Other languages

English (en)

Inventor

Stefano Turchetta

Sabina Pucci

Gianfranco Piccoli

Giovanni Frare

Original Assignee

Recordati Chem Pharm

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-09-10

Filing date

1994-02-03

Publication date

1997-05-15

1993-09-10 Priority claimed from IT93RM000608A external-priority patent/IT1266486B1/it

1993-11-03 Priority claimed from IT93MI002324A external-priority patent/IT1266654B1/it

1994-02-03 Application filed by Recordati Chem Pharm filed Critical Recordati Chem Pharm

1997-05-15 Application granted granted Critical

1997-05-15 Publication of ATE152722T1 publication Critical patent/ATE152722T1/de

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AT94906897T 1993-09-10 1994-02-03 Verfahren zur herstellung von 9-(2-hydroxy)- ethoxy-guanin ATE152722T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT93RM000608A IT1266486B1 (it)	1993-09-10	1993-09-10	Procedimento per la preparazione della 9-(2-idrossi)etossimetil- guanina.
IT93MI002324A IT1266654B1 (it)	1993-11-03	1993-11-03	Procedimento per la purificazione della 9-(2-idrossi) etossimetilguanina

Publications (1)

Publication Number	Publication Date
ATE152722T1 true ATE152722T1 (de)	1997-05-15

Family

ID=26331057

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94906897T ATE152722T1 (de)	1993-09-10	1994-02-03	Verfahren zur herstellung von 9-(2-hydroxy)- ethoxy-guanin

Country Status (21)

Country	Link
US (1)	US5756737A (de)
EP (1)	EP0717744B1 (de)
JP (1)	JPH09502707A (de)
CN (1)	CN1041632C (de)
AT (1)	ATE152722T1 (de)
AU (1)	AU685774B2 (de)
BG (1)	BG61569B1 (de)
BR (1)	BR9407426A (de)
CA (1)	CA2171283A1 (de)
DE (1)	DE69403087T2 (de)
DK (1)	DK0717744T3 (de)
ES (1)	ES2103575T3 (de)
FI (1)	FI961054A7 (de)
GR (1)	GR3024343T3 (de)
HU (1)	HU214841B (de)
NO (1)	NO960927D0 (de)
NZ (1)	NZ261573A (de)
PL (1)	PL174765B1 (de)
RU (1)	RU2125570C1 (de)
SK (1)	SK29396A3 (de)
WO (1)	WO1995007281A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19536164A1 (de) *	1995-09-28	1997-04-03	Boehringer Ingelheim Kg	Verbessertes Verfahren zur Herstellung von 9-[(2-Hyroxyethoxy)methyl]guanin (Acyclovir)
IN179493B (de) *	1996-02-22	1997-10-11	Lupin Laboraties Ltd
EP0976751A1 (de) *	1996-04-09	2000-02-02	Lupin Laboratories Limited	Ein Verfahren zur Isomerisierung von einem N-7 Isomer in einem N-9 Isomer verwendbar in der Synthese von acyclischen Nucleosiden
US6440980B1 (en) *	1996-09-17	2002-08-27	Avanir Pharmaceuticals	Synergistic inhibition of viral replication by long-chain hydrocarbons and nucleoside analogs
US20050176956A1 (en) *	2001-10-15	2005-08-11	Babu Jayachandra S.	Process for the preparation of ganciclovir intermediate n2-acetyl-9-(1,3-diacetoxy-2-propoxymethyl) guanine
CA2421026C (en) *	2001-10-16	2005-02-15	Avanir Pharmaceuticals	Viral inhibition by n-docosanol
US7078524B2 (en) *	2002-11-22	2006-07-18	Ranbaxy Laboratories Limited	Process for the synthesis of ganciclovir
ES2289650T3 (es) *	2004-03-03	2008-02-01	Chemi S.P.A.	Sal monosodica del acido 3-piridil-1-hidroxietiliden-1,1-bifosfonico amorfa y procedimiento para la preparacion de la misma.
US7700694B2 (en) *	2006-04-28	2010-04-20	Tsrc Corporation	Catalyst composition and method for hydrogenating a polymer having a conjugated diene
CN117551100B (zh) *	2024-01-12	2024-03-12	苏州诺维康生物科技有限公司	(s)-9-[3-(4,4'-双甲氧基三苯甲基)-2-羟基丙基]-n2-乙酰基鸟嘌呤的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4146715A (en) *	1975-08-27	1979-03-27	Burroughs Wellcome Co.	2-amido-9-(2-acyloxyethoxymethyl)hypoxanthines
YU41079B (en) *	1976-08-27	1986-12-31	Wellcome Found	Process for the synthesis of substituted purine compounds
US4816447A (en) *	1981-08-26	1989-03-28	Merck & Co., Inc.	Anti-viral guanine compounds
US4609661A (en) *	1982-08-09	1986-09-02	Syntex (U.S.A.) Inc.	Substituted 9-(1-O- or 3-O-monosubstituted or 1,3-di-O-substituted propoxymethyl)purines as antiviral agents
JPS5980685A (ja) *	1982-10-29	1984-05-10	Fujisawa Pharmaceut Co Ltd	Ｎ−低級アルカノイルグアニン誘導体およびそれを用いる方法
YU45690B (sh) *	1984-12-22	1992-07-20	Krka Tovarna Zdraviln.Sol.O.	Postopek za pripravo 9-(2-hidroksietoksimetil)-gvanina
SU1705296A1 (ru) *	1988-03-31	1992-01-15	Институт Органического Синтеза Ан Латвсср	Способ получени 9-(2-оксиэтоксиметил)гуанина
JP3225545B2 (ja) *	1991-09-18	2001-11-05	味の素株式会社	非環状ヌクレオシド類の製造法

1994
- 1994-02-03 PL PL94313322A patent/PL174765B1/pl unknown
- 1994-02-03 HU HU9600556A patent/HU214841B/hu not_active IP Right Cessation
- 1994-02-03 BR BR9407426A patent/BR9407426A/pt not_active Application Discontinuation
- 1994-02-03 AU AU60383/94A patent/AU685774B2/en not_active Ceased
- 1994-02-03 US US08/602,789 patent/US5756737A/en not_active Expired - Fee Related
- 1994-02-03 DK DK94906897.7T patent/DK0717744T3/da active
- 1994-02-03 JP JP7508403A patent/JPH09502707A/ja active Pending
- 1994-02-03 CA CA002171283A patent/CA2171283A1/en not_active Abandoned
- 1994-02-03 WO PCT/EP1994/000308 patent/WO1995007281A1/en not_active Ceased
- 1994-02-03 CN CN94193288A patent/CN1041632C/zh not_active Expired - Fee Related
- 1994-02-03 FI FI961054A patent/FI961054A7/fi unknown
- 1994-02-03 SK SK293-96A patent/SK29396A3/sk unknown
- 1994-02-03 DE DE69403087T patent/DE69403087T2/de not_active Expired - Fee Related
- 1994-02-03 ES ES94906897T patent/ES2103575T3/es not_active Expired - Lifetime
- 1994-02-03 RU RU96107229A patent/RU2125570C1/ru active
- 1994-02-03 EP EP94906897A patent/EP0717744B1/de not_active Expired - Lifetime
- 1994-02-03 AT AT94906897T patent/ATE152722T1/de not_active IP Right Cessation
- 1994-02-03 NZ NZ261573A patent/NZ261573A/en unknown
1996
- 1996-03-04 BG BG100395A patent/BG61569B1/bg unknown
- 1996-03-07 NO NO960927A patent/NO960927D0/no unknown
1997
- 1997-07-31 GR GR970401990T patent/GR3024343T3/el unknown

Also Published As

Publication number	Publication date
DE69403087T2 (de)	1997-08-14
WO1995007281A1 (en)	1995-03-16
EP0717744B1 (de)	1997-05-07
JPH09502707A (ja)	1997-03-18
NO960927L (no)	1996-03-07
NO960927D0 (no)	1996-03-07
FI961054A0 (fi)	1996-03-07
CN1130382A (zh)	1996-09-04
HUT74295A (en)	1996-11-28
NZ261573A (en)	1997-02-24
FI961054L (fi)	1996-03-07
FI961054A7 (fi)	1996-03-07
AU685774B2 (en)	1998-01-29
BG100395A (bg)	1996-09-30
CN1041632C (zh)	1999-01-13
RU2125570C1 (ru)	1999-01-27
DE69403087D1 (de)	1997-06-12
BG61569B1 (en)	1997-12-30
HU214841B (hu)	1998-06-29
PL174765B1 (pl)	1998-09-30
PL313322A1 (en)	1996-06-24
ES2103575T3 (es)	1997-09-16
DK0717744T3 (da)	1997-12-08
AU6038394A (en)	1995-03-27
SK29396A3 (en)	1996-10-02
HU9600556D0 (en)	1996-05-28
BR9407426A (pt)	1996-04-09
CA2171283A1 (en)	1995-03-16
US5756737A (en)	1998-05-26
EP0717744A1 (de)	1996-06-26
GR3024343T3 (en)	1997-10-31

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Legal Events

Date	Code	Title	Description
1997-10-15	UEP	Publication of translation of european patent specification
2000-11-15	REN	Ceased due to non-payment of the annual fee