ATE154008T1 - Lacton-verbindung und verfahren zu ihrer herstellung - Google Patents

Lacton-verbindung und verfahren zu ihrer herstellung

Info

Publication number
ATE154008T1
ATE154008T1 AT94300732T AT94300732T ATE154008T1 AT E154008 T1 ATE154008 T1 AT E154008T1 AT 94300732 T AT94300732 T AT 94300732T AT 94300732 T AT94300732 T AT 94300732T AT E154008 T1 ATE154008 T1 AT E154008T1
Authority
AT
Austria
Prior art keywords
lactone compound
producing
zero
stereoisomer
chem
Prior art date
Application number
AT94300732T
Other languages
English (en)
Inventor
Masayasu Tabe
Kenji Manabe
Koji Tomimori
Atsuo Hazato
Osami Takenouchi
Yoshiaki Azuma
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Application granted granted Critical
Publication of ATE154008T1 publication Critical patent/ATE154008T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Furan Compounds (AREA)
AT94300732T 1993-02-05 1994-02-01 Lacton-verbindung und verfahren zu ihrer herstellung ATE154008T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP1870393 1993-02-05
JP6843493 1993-03-26

Publications (1)

Publication Number Publication Date
ATE154008T1 true ATE154008T1 (de) 1997-06-15

Family

ID=26355421

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94300732T ATE154008T1 (de) 1993-02-05 1994-02-01 Lacton-verbindung und verfahren zu ihrer herstellung

Country Status (11)

Country Link
US (1) US5604257A (de)
EP (1) EP0619305B1 (de)
JP (1) JP3588369B2 (de)
KR (1) KR940019700A (de)
CN (1) CN1055922C (de)
AT (1) ATE154008T1 (de)
AU (1) AU686578B2 (de)
CA (1) CA2114830C (de)
DE (1) DE69403541T2 (de)
DK (1) DK0619305T3 (de)
TW (1) TW364905B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0854139B1 (de) * 1994-06-07 2001-09-05 Teijin Limited Vitamin D3-Derivate und ein Verfahren zu ihrer Herstellung
US6020500A (en) * 1995-08-22 2000-02-01 The Lubrizol Corporation Hydroxy-substituted monolactones useful as intermediates for preparing lubricating oil and fuel additives
DE19619036A1 (de) 1996-04-30 1997-11-13 Schering Ag Neue Vitamin D-Derivate mit carbo- oder heterocyclischen Substituenten an C-25, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
JP3020141B2 (ja) * 1996-10-07 2000-03-15 株式会社富士薬品 経鼻投与用製剤
EP1609469A3 (de) * 1996-12-13 2009-07-29 ZymoGenetics, Inc. Zusammenstellungen und Methoden zur Stimulierung des Knochenwachstums
US6080779A (en) * 1996-12-13 2000-06-27 Osteoscreen, Inc. Compositions and methods for stimulating bone growth
US6022887A (en) * 1996-12-13 2000-02-08 Osteoscreen, Inc. Compositions and methods for stimulating bone growth
US6376476B1 (en) * 1996-12-13 2002-04-23 Zymogenetics Corporation Isoprenoid pathway inhibitors for stimulating bone growth
AUPP332898A0 (en) * 1998-05-04 1998-05-28 Unisearch Limited Pharmaceutical composition
EP1123921A4 (de) * 1998-10-23 2003-08-20 Teijin Ltd Vitamin d 3 derivate und diese enthaltende heilmittel für entzündliche erkrankungen der atemwege
US7041309B2 (en) * 2002-06-13 2006-05-09 Neuropro Technologies, Inc. Spinal fusion using an HMG-CoA reductase inhibitor

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58118516A (ja) * 1981-12-29 1983-07-14 Teijin Ltd 1α,25−ジヒドロキシビタミンD↓3−26,23−ラクトンを含有するカルシユウム調節剤
DE3247836A1 (de) * 1981-12-29 1983-07-07 Teijin Ltd., Osaka Arzneimittel und verwendung derselben zur steuerung der serumcalciumkonzentration bei warmbluetern
JPS58210011A (ja) * 1982-05-31 1983-12-07 Kureha Chem Ind Co Ltd 抗腫瘍剤
JPS60185715A (ja) * 1984-03-05 1985-09-21 Teijin Ltd 骨形成促進剤
JPS62175496A (ja) * 1986-01-30 1987-08-01 Teijin Ltd ステロイド化合物及びその製造法

Also Published As

Publication number Publication date
EP0619305A1 (de) 1994-10-12
TW364905B (en) 1999-07-21
DE69403541D1 (de) 1997-07-10
DK0619305T3 (da) 1997-07-07
JPH06329696A (ja) 1994-11-29
AU5486694A (en) 1994-08-11
AU686578B2 (en) 1998-02-12
DE69403541T2 (de) 1997-09-25
CN1108244A (zh) 1995-09-13
CA2114830C (en) 2000-06-06
KR940019700A (ko) 1994-09-14
CA2114830A1 (en) 1994-08-06
US5604257A (en) 1997-02-18
CN1055922C (zh) 2000-08-30
JP3588369B2 (ja) 2004-11-10
EP0619305B1 (de) 1997-06-04

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee