ATE154387T1 - Cdna für ratten c-typ natriuretisches peptid und vorläuferprotein - Google Patents
Cdna für ratten c-typ natriuretisches peptid und vorläuferproteinInfo
- Publication number
- ATE154387T1 ATE154387T1 AT91115393T AT91115393T ATE154387T1 AT E154387 T1 ATE154387 T1 AT E154387T1 AT 91115393 T AT91115393 T AT 91115393T AT 91115393 T AT91115393 T AT 91115393T AT E154387 T1 ATE154387 T1 AT E154387T1
- Authority
- AT
- Austria
- Prior art keywords
- cdna
- precursor protein
- rats
- type natriuretic
- natriuretic peptide
- Prior art date
Links
- 239000002243 precursor Substances 0.000 title abstract 4
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 102000012421 C-Type Natriuretic Peptide Human genes 0.000 title 1
- 101800000060 C-type natriuretic peptide Proteins 0.000 title 1
- 241000700159 Rattus Species 0.000 title 1
- 239000002934 diuretic Substances 0.000 abstract 2
- 230000001452 natriuretic effect Effects 0.000 abstract 2
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 239000002299 complementary DNA Substances 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP02241074A JP3026352B2 (ja) | 1990-09-11 | 1990-09-11 | ラットCNPcDNA及び前駆体蛋白 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE154387T1 true ATE154387T1 (de) | 1997-06-15 |
Family
ID=17068911
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91115393T ATE154387T1 (de) | 1990-09-11 | 1991-09-11 | Cdna für ratten c-typ natriuretisches peptid und vorläuferprotein |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5973134A (de) |
| EP (1) | EP0475394B1 (de) |
| JP (1) | JP3026352B2 (de) |
| AT (1) | ATE154387T1 (de) |
| DE (1) | DE69126487T2 (de) |
| DK (1) | DK0475394T3 (de) |
| ES (1) | ES2104639T3 (de) |
| GR (1) | GR3024580T3 (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL142118A0 (en) * | 2001-03-20 | 2002-03-10 | Prochon Biotech Ltd | Method and composition for treatment of skeletal dysplasias |
| CN1960757A (zh) | 2004-03-31 | 2007-05-09 | 中尾一和 | 身高增加用组合物 |
| CN1960758B (zh) | 2004-03-31 | 2014-10-22 | 中外制药株式会社 | 关节炎的治疗剂或预防剂 |
| DE602005027461D1 (de) | 2004-04-21 | 2011-05-26 | Enobia Pharma Inc | Konjugate zur zuführung an knochen und verfahren zu deren verwendung beim hinführen von proteinen zum knochen |
| JP6055779B2 (ja) | 2010-12-27 | 2016-12-27 | アレクシオン ファーマシューティカルズ, インコーポレイテッド | ナトリウム利尿ペプチドを含む組成物およびその使用方法 |
| US10052366B2 (en) | 2012-05-21 | 2018-08-21 | Alexion Pharmaceuticsl, Inc. | Compositions comprising alkaline phosphatase and/or natriuretic peptide and methods of use thereof |
| US10822596B2 (en) | 2014-07-11 | 2020-11-03 | Alexion Pharmaceuticals, Inc. | Compositions and methods for treating craniosynostosis |
| JP6787894B2 (ja) | 2014-12-05 | 2020-11-18 | アレクシオン ファーマシューティカルズ, インコーポレイテッド | 組換えアルカリホスファターゼを用いた発作の処置 |
| JP6868561B2 (ja) | 2015-01-28 | 2021-05-12 | アレクシオン ファーマシューティカルズ, インコーポレイテッド | アルカリホスファターゼ欠損を有する被験者を治療する方法 |
| JP6993961B2 (ja) | 2015-08-17 | 2022-01-14 | アレクシオン ファーマシューティカルズ, インコーポレイテッド | アルカリホスファターゼの製造 |
| EP3355904A4 (de) | 2015-09-28 | 2019-06-12 | Alexion Pharmaceuticals, Inc. | Identifizierung wirksamer dosierungsschemata für gewebeunspezifische alkalische phosphatase-enzymersatztherapie von hypophosphatasie |
| WO2017074466A1 (en) | 2015-10-30 | 2017-05-04 | Alexion Pharmaceuticals, Inc. | Methods for treating craniosynostosis in a patient |
| WO2017155569A1 (en) | 2016-03-08 | 2017-09-14 | Alexion Pharmaceuticals, Inc. | Methods for treating hypophosphatasia in children |
| KR20240160671A (ko) | 2016-04-01 | 2024-11-11 | 알렉시온 파마슈티칼스, 인코포레이티드 | 알칼리성 포스파타아제로 근육 약화의 치료 |
| US10898549B2 (en) | 2016-04-01 | 2021-01-26 | Alexion Pharmaceuticals, Inc. | Methods for treating hypophosphatasia in adolescents and adults |
| EP3464573B1 (de) | 2016-06-06 | 2026-03-04 | Alexion Pharmaceuticals, Inc. | Auswirkungen von metallen auf die herstellung von alkalischen phosphatasen |
| EP3500289B1 (de) | 2016-08-18 | 2024-10-09 | Alexion Pharmaceuticals, Inc. | Asfotase alfa zur behandlung von tracheobronchomalazie |
| KR20190129058A (ko) | 2017-03-31 | 2019-11-19 | 알렉시온 파마슈티칼스, 인코포레이티드 | 성인 및 청소년에서 저포스파타제증 (hpp)을 치료하는 방법 |
| US11913039B2 (en) | 2018-03-30 | 2024-02-27 | Alexion Pharmaceuticals, Inc. | Method for producing recombinant alkaline phosphatase |
| ES2972119T3 (es) | 2018-08-10 | 2024-06-11 | Alexion Pharma Inc | Cicatrización ósea en implantes utilizando fosfatasa alcalina |
| KR20220111693A (ko) | 2019-12-09 | 2022-08-09 | 알렉시온 파마슈티칼스, 인코포레이티드 | 알칼리성 포스파타제 폴리펩티드 및 이의 이용 방법 |
| US12083169B2 (en) | 2021-02-12 | 2024-09-10 | Alexion Pharmaceuticals, Inc. | Alkaline phosphatase polypeptides and methods of use thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3026351B2 (ja) * | 1990-07-13 | 2000-03-27 | 壽之 松尾 | ブタcnp遺伝子及び前駆体蛋白 |
-
1990
- 1990-09-11 JP JP02241074A patent/JP3026352B2/ja not_active Expired - Lifetime
-
1991
- 1991-09-11 EP EP91115393A patent/EP0475394B1/de not_active Expired - Lifetime
- 1991-09-11 AT AT91115393T patent/ATE154387T1/de not_active IP Right Cessation
- 1991-09-11 DK DK91115393.0T patent/DK0475394T3/da active
- 1991-09-11 US US07/757,606 patent/US5973134A/en not_active Expired - Lifetime
- 1991-09-11 DE DE69126487T patent/DE69126487T2/de not_active Expired - Lifetime
- 1991-09-11 ES ES91115393T patent/ES2104639T3/es not_active Expired - Lifetime
-
1997
- 1997-08-29 GR GR970402222T patent/GR3024580T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US5973134A (en) | 1999-10-26 |
| ES2104639T3 (es) | 1997-10-16 |
| JP3026352B2 (ja) | 2000-03-27 |
| DE69126487D1 (de) | 1997-07-17 |
| EP0475394B1 (de) | 1997-06-11 |
| EP0475394A3 (en) | 1992-09-16 |
| DE69126487T2 (de) | 1997-11-27 |
| GR3024580T3 (en) | 1997-12-31 |
| DK0475394T3 (da) | 1997-07-07 |
| JPH04121190A (ja) | 1992-04-22 |
| EP0475394A2 (de) | 1992-03-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |