ATE154388T1 - Verwendung von modifiziertem heparin kofaktor ii - Google Patents

Verwendung von modifiziertem heparin kofaktor ii

Info

Publication number: ATE154388T1
Authority: AT; Austria
Prior art keywords: heparin cofactor; modified heparin; hcii; modified; cofactor
Prior art date: 1989-10-20

Application number

AT90870188T

Other languages

English (en)

Inventor

Douglas Meyer Tollefsen

Vivianna Maia Derechin

Morey Alan Blinder

Original Assignee

Univ Washington

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-10-20

Filing date

1990-10-15

Publication date

1997-06-15

1990-10-15 Application filed by Univ Washington filed Critical Univ Washington

1997-06-15 Application granted granted Critical

1997-06-15 Publication of ATE154388T1 publication Critical patent/ATE154388T1/de

Links

HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical class OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 title abstract 2
102000004032 Heparin Cofactor II Human genes 0.000 title abstract 2
108090000481 Heparin Cofactor II Proteins 0.000 title abstract 2
101100450563 Mus musculus Serpind1 gene Proteins 0.000 abstract 2
108090000190 Thrombin Proteins 0.000 abstract 1
239000004019 antithrombin Substances 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
229960004072 thrombin Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8121—Serpins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Diabetes (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Hematology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Saccharide Compounds (AREA)

AT90870188T 1989-10-20 1990-10-15 Verwendung von modifiziertem heparin kofaktor ii ATE154388T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/424,440 US5102995A (en)	1989-10-20	1989-10-20	Dna encoding modified heparin cofactor ii

Publications (1)

Publication Number	Publication Date
ATE154388T1 true ATE154388T1 (de)	1997-06-15

Family

ID=23682642

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90870188T ATE154388T1 (de)	1989-10-20	1990-10-15	Verwendung von modifiziertem heparin kofaktor ii

Country Status (9)

Country	Link
US (1)	US5102995A (de)
EP (1)	EP0424351B1 (de)
JP (1)	JPH03139280A (de)
AT (1)	ATE154388T1 (de)
CA (1)	CA2028082A1 (de)
DE (1)	DE69030909T2 (de)
DK (1)	DK0424351T3 (de)
ES (1)	ES2104598T3 (de)
GR (1)	GR3024588T3 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6291662B1 (en)	1984-12-05	2001-09-18	Amgen Inc.	Recombinant methods for production of serine protease inhibitors and DNA sequences
US5871956A (en) *	1984-12-06	1999-02-16	Amgen Inc.	Recombinant methods for production of serine inhibitors and DNA sequences useful for same
US5900400A (en) *	1984-12-06	1999-05-04	Amgen Inc.	Serine protease inhibitor analogs
US6132990A (en) *	1984-12-06	2000-10-17	Amgen Boulder Inc.	Recombinant methods for production of serine protease inhibitors and DNA sequences useful for same
GB9024685D0 (en) *	1990-11-13	1991-01-02	Raleigh Industries Ltd	Cycle seat pillar mounting
JP3479539B2 (ja) *	1992-04-10	2003-12-15	エーザイ株式会社	ヒトアンチトロンビンｉｉｉ変異体
US6303691B1 (en)	1992-07-31	2001-10-16	Exxon Mobil Chemical Patents Inc.	Impact modification of polyamides
US6869925B1 (en) *	1992-09-09	2005-03-22	Amgen Inc.	Inhibition of retrovirus infection
US6017880A (en) *	1994-03-09	2000-01-25	Amgen Inc.	Inhibition of retrovirus infection
JPH09176040A (ja) *	1995-12-27	1997-07-08	Green Cross Corp:The	ヘパリンコファクターｉｉの医薬用途
AU2878199A (en) *	1998-02-27	1999-09-15	University Of North Carolina At Chapel Hill, The	Mutant heparin cofactor ii
AU2746399A (en) *	1998-03-09	1999-09-27	Welfide Corporation	Heparin cofactor ii-containing compositions and method for stabilizing the same
GB0916578D0 (en) *	2009-09-22	2009-10-28	Malmsten Nils M	Polypeptides and uses thereof
GB2500184A (en) *	2012-03-12	2013-09-18	Ximmune Ab	Polypeptide derived from helix A of heparin cofactor II
US20180078916A1 (en) *	2015-03-18	2018-03-22	Carnegie Mellon University	Lignin-based surfactants

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3521226A1 (de) *	1985-02-08	1986-08-14	Hoechst Ag, 6230 Frankfurt	Gene fuer biologisch aktive proteine
US4861865A (en) *	1989-01-23	1989-08-29	Washington University	Novel antithrombin peptide

1989
- 1989-10-20 US US07/424,440 patent/US5102995A/en not_active Expired - Fee Related
1990
- 1990-10-15 DE DE69030909T patent/DE69030909T2/de not_active Expired - Fee Related
- 1990-10-15 EP EP90870188A patent/EP0424351B1/de not_active Expired - Lifetime
- 1990-10-15 DK DK90870188.1T patent/DK0424351T3/da active
- 1990-10-15 ES ES90870188T patent/ES2104598T3/es not_active Expired - Lifetime
- 1990-10-15 AT AT90870188T patent/ATE154388T1/de active
- 1990-10-19 CA CA002028082A patent/CA2028082A1/en not_active Abandoned
- 1990-10-19 JP JP2279543A patent/JPH03139280A/ja active Pending
1997
- 1997-08-29 GR GR970402232T patent/GR3024588T3/el unknown

Also Published As

Publication number	Publication date
EP0424351B1 (de)	1997-06-11
EP0424351A2 (de)	1991-04-24
CA2028082A1 (en)	1991-04-21
ES2104598T3 (es)	1997-10-16
DK0424351T3 (da)	1997-10-13
GR3024588T3 (en)	1997-12-31
EP0424351A3 (en)	1991-10-09
DE69030909T2 (de)	1998-01-29
JPH03139280A (ja)	1991-06-13
US5102995A (en)	1992-04-07
DE69030909D1 (de)	1997-07-17

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