ATE157883T1 - Verfahren zur herstellung von piroxicam/cyclodextrin-komplexen, die erhaltenen produkte und ihre pharmazeutischen zusammensetzungen - Google Patents

Verfahren zur herstellung von piroxicam/cyclodextrin-komplexen, die erhaltenen produkte und ihre pharmazeutischen zusammensetzungen

Info

Publication number
ATE157883T1
ATE157883T1 AT91104649T AT91104649T ATE157883T1 AT E157883 T1 ATE157883 T1 AT E157883T1 AT 91104649 T AT91104649 T AT 91104649T AT 91104649 T AT91104649 T AT 91104649T AT E157883 T1 ATE157883 T1 AT E157883T1
Authority
AT
Austria
Prior art keywords
piroxicam
pharmaceutical compositions
products obtained
producing
cyclodextrin complexes
Prior art date
Application number
AT91104649T
Other languages
English (en)
Inventor
Fabio Carli
Paolo Chiesi
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Application granted granted Critical
Publication of ATE157883T1 publication Critical patent/ATE157883T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nanotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT91104649T 1990-03-27 1991-03-25 Verfahren zur herstellung von piroxicam/cyclodextrin-komplexen, die erhaltenen produkte und ihre pharmazeutischen zusammensetzungen ATE157883T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT19829A IT1241088B (it) 1990-03-27 1990-03-27 Procedimento per la preparazione di complessi piroxicam/ciclodestrina,prodotti ottenuti e loro composizioni farmaceutiche

Publications (1)

Publication Number Publication Date
ATE157883T1 true ATE157883T1 (de) 1997-09-15

Family

ID=11161628

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91104649T ATE157883T1 (de) 1990-03-27 1991-03-25 Verfahren zur herstellung von piroxicam/cyclodextrin-komplexen, die erhaltenen produkte und ihre pharmazeutischen zusammensetzungen

Country Status (24)

Country Link
US (1) US5164380A (de)
EP (1) EP0449167B1 (de)
JP (1) JPH04221314A (de)
KR (1) KR0175934B1 (de)
AT (1) ATE157883T1 (de)
AU (1) AU644417B2 (de)
CA (1) CA2039052C (de)
CZ (1) CZ280164B6 (de)
DE (1) DE69127566T2 (de)
DK (1) DK0449167T3 (de)
ES (1) ES2107430T3 (de)
FI (1) FI102461B1 (de)
GR (1) GR3025305T3 (de)
HU (1) HU217834B (de)
IE (1) IE910969A1 (de)
IL (1) IL97693A (de)
IT (1) IT1241088B (de)
MA (1) MA22089A1 (de)
NO (1) NO178456C (de)
NZ (1) NZ237583A (de)
PT (1) PT97176B (de)
RU (1) RU2034544C1 (de)
SK (1) SK279171B6 (de)
ZA (1) ZA912282B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5254541A (en) * 1991-11-15 1993-10-19 Merck Frosst Canada, Inc. (Quinolin-2-ylmethoxy)indole/cyclodextrin complex
IL111184A (en) * 1993-10-08 2000-08-13 Farmarc Nederland B V Of Cito Crystalline inclusion complex of diclofenac with unsubstituted beta-cyclodextrin
ZA959469B (en) * 1994-11-15 1996-05-15 South African Druggists Ltd Pharmaceutical composition
US7255877B2 (en) 1996-08-22 2007-08-14 Jagotec Ag Fenofibrate microparticles
US6465016B2 (en) 1996-08-22 2002-10-15 Research Triangle Pharmaceuticals Cyclosporiine particles
IT1295289B1 (it) * 1997-10-07 1999-05-04 Telos S R L Co-macinati per uso cosmetico e dermatologico
US6979456B1 (en) 1998-04-01 2005-12-27 Jagotec Ag Anticancer compositions
KR100635456B1 (ko) 1998-05-29 2006-10-18 스키에파마 캐나다 인코포레이티드 열보호화 마이크로입자 조성물 및 그의 말단의 스팀멸균방법
IL143197A0 (en) 1998-11-20 2002-04-21 Rtp Pharma Inc Dispersible phospholipid stabilized microparticles
US20060073188A1 (en) * 1999-03-31 2006-04-06 Pierre Fabre Medicament Fast-dissolving isotropic expanded microporous composition or structure for pharmaceutical, veterinary, dietetic, food or cosmetic use and method for obtaining same
ITMI20012749A1 (it) * 2001-12-21 2003-06-21 Chiesi Farma Spa Procedimento per la preparazione mediante trattamento con microonde di composti di inclusione tra farmaco e ciclodestrine e prodotti ottenut
DK2260871T3 (da) 2004-04-01 2013-08-26 Pf Medicament Inklusionskomplekser omfattende piroxicam, en cyklodextrin og arginin
FR2868315B1 (fr) * 2004-04-01 2006-07-14 Pierre Fabre Medicament Sa Procede de preparation d'un compose d'inclusion soluble de substances actives dans une molecule hote avec l'aide d'un agent d'interaction par fluide supercritique
US8715731B2 (en) * 2006-03-22 2014-05-06 Isp Investments Inc. Process of reducing the bitter taste of water soluble actives by co-grinding the active with β cyclodextrin
JP5552400B2 (ja) * 2010-09-07 2014-07-16 東亜薬品株式会社 生薬類の苦味・不快味をマスキングした顆粒剤、及び口腔内速崩壊錠
CN102008450B (zh) * 2010-12-10 2013-01-30 杭州艾瑞莎生物医药科技有限公司 一种药物-环糊精纳米颗粒及其制备方法
ITMI20120092A1 (it) 2012-01-26 2013-07-27 Micro Macinazione S A Compositi di inclusione farmaco-carrier preparati con processo di attivazione meccano-chimica mediante mulini a getto di fluido ad alta energia
ITUB20161027A1 (it) * 2016-02-24 2017-08-24 Altergon Sa Preparazioni farmaceutiche oromucosali ad elevata biodisponibilita’ a base di ciclodestrina e sucralosio
US10532102B2 (en) 2016-08-19 2020-01-14 Foresee Pharmaceuticals Co., Ltd. Pharmaceutical composition and methods of uses
GB202105833D0 (en) * 2021-04-23 2021-06-09 Nacamed As Silicon particles for drug delivery
KR102337124B1 (ko) * 2021-05-13 2021-12-10 (주)바이오제닉스 탈모 개선용 복합 파우더 및 이를 포함하는 모발용 화장료 조성물

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5920230A (ja) * 1982-07-19 1984-02-01 チバ−ガイギ−・アクチエンゲゼルシヤフト ピルプロフエン含有薬剤
IT1196033B (it) * 1984-02-22 1988-11-10 Chiesi Farma Spa Composto ad attivita' antiinfiammatoria ottenuto per complessazione con beta-ciclodestrina e relative formulazioni farmaceutiche
JPS6165805A (ja) * 1984-09-10 1986-04-04 Nippon Ekishiyou Kk 防殺虫フイルムの製造方法
US4579846A (en) * 1984-10-11 1986-04-01 Pfizer Inc. Antiinflammatory compositions and methods
US4672061A (en) * 1985-01-28 1987-06-09 Pfizer Inc. Antiinflammatory compositions and methods
IT1196307B (it) * 1984-10-22 1988-11-16 Chiesi Farma Spa Formulazioni farmaceutiche acquose di piroxicam monoidrato
US4888343A (en) * 1986-09-15 1989-12-19 Bristol-Myers Company Pharmaceutical compositions for relief of dysmenorrhea and/or premenstrual syndrome and process
WO1989003682A1 (en) * 1987-10-26 1989-05-05 Pfizer Inc. Benzothiazine dioxide derivatives
US5068226A (en) * 1987-12-07 1991-11-26 Cyclex, Inc. Pharmaceutical preparations containing cyclodextrins and their use in iontophoretic therapies
IT1216686B (it) * 1988-04-01 1990-03-08 Chiesi Farma Spa Formulazioni farmaceutiche acquose di piroxicam e procedimento per laloro preparazione.
CA1321192C (en) * 1988-04-20 1993-08-10 Abdul Majid Inclusion complexes of cyclodextrins by agglomeration
IT1227626B (it) * 1988-11-28 1991-04-23 Vectorpharma Int Farmaci supportati aventi velocita' di dissoluzione aumentata e procedimento per la loro preparazione

Also Published As

Publication number Publication date
NO178456B (no) 1995-12-27
RU2034544C1 (ru) 1995-05-10
NO911216D0 (no) 1991-03-25
DE69127566T2 (de) 1998-02-12
IT9019829A0 (it) 1990-03-27
JPH04221314A (ja) 1992-08-11
SK279171B6 (sk) 1998-07-08
DK0449167T3 (da) 1998-03-09
ZA912282B (en) 1991-12-24
EP0449167B1 (de) 1997-09-10
FI102461B (fi) 1998-12-15
HU217834B (hu) 2000-04-28
IT1241088B (it) 1993-12-29
NZ237583A (en) 1992-08-26
IT9019829A1 (it) 1991-09-27
CA2039052A1 (en) 1991-09-28
CZ280164B6 (cs) 1995-11-15
HU911016D0 (en) 1991-10-28
NO178456C (no) 1996-04-03
US5164380A (en) 1992-11-17
AU644417B2 (en) 1993-12-09
EP0449167A1 (de) 1991-10-02
NO911216L (no) 1991-09-30
ES2107430T3 (es) 1997-12-01
DE69127566D1 (de) 1997-10-16
CS9100833A2 (en) 1991-10-15
FI911448A0 (fi) 1991-03-26
AU7383891A (en) 1991-10-03
MA22089A1 (fr) 1991-10-01
CA2039052C (en) 2002-07-30
PT97176B (pt) 1998-07-31
FI911448A7 (fi) 1991-09-28
HUT60738A (en) 1992-10-28
GR3025305T3 (en) 1998-02-27
IL97693A (en) 1995-03-30
IL97693A0 (en) 1992-06-21
KR910016333A (ko) 1991-11-05
FI102461B1 (fi) 1998-12-15
IE910969A1 (en) 1991-10-09
KR0175934B1 (ko) 1999-03-20
PT97176A (pt) 1991-11-29

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Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee