ATE158297T1 - Halbsynthetische gangliosidanaloge - Google Patents

Halbsynthetische gangliosidanaloge

Info

Publication number: ATE158297T1
Authority: AT; Austria
Prior art keywords: acyl; dilysogangliosides; semi; derived; carbon atoms
Prior art date: 1989-07-27

Application number

AT90402139T

Other languages

English (en)

Inventor

Valle Francesco Della

Aurelio Romeo

Original Assignee

Fidia Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-07-27

Filing date

1990-07-25

Publication date

1997-10-15

1990-07-25 Application filed by Fidia Spa filed Critical Fidia Spa

1997-10-15 Application granted granted Critical

1997-10-15 Publication of ATE158297T1 publication Critical patent/ATE158297T1/de

Links

150000002270 gangliosides Chemical class 0.000 title 1
125000002252 acyl group Chemical group 0.000 abstract 2
125000001931 aliphatic group Chemical group 0.000 abstract 2
125000004432 carbon atom Chemical group C* 0.000 abstract 2
QSJXEFYPDANLFS-UHFFFAOYSA-N Diacetyl Chemical class CC(=O)C(C)=O QSJXEFYPDANLFS-UHFFFAOYSA-N 0.000 abstract 1
102000003923 Protein Kinase C Human genes 0.000 abstract 1
108090000315 Protein Kinase C Proteins 0.000 abstract 1
125000000218 acetic acid group Chemical class C(C)(=O)* 0.000 abstract 1
230000004913 activation Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
210000000653 nervous system Anatomy 0.000 abstract 1
230000007170 pathology Effects 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
- C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Genetics & Genomics (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Molecular Biology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Biotechnology (AREA)
Public Health (AREA)
Biochemistry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Crystallography & Structural Chemistry (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Lead Frames For Integrated Circuits (AREA)
Magnetic Resonance Imaging Apparatus (AREA)

AT90402139T 1989-07-27 1990-07-25 Halbsynthetische gangliosidanaloge ATE158297T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT8948246A IT1232175B (it)	1989-07-27	1989-07-27	Analoghi semisintetici di gangliosidi

Publications (1)

Publication Number	Publication Date
ATE158297T1 true ATE158297T1 (de)	1997-10-15

Family

ID=11265466

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90402139T ATE158297T1 (de)	1989-07-27	1990-07-25	Halbsynthetische gangliosidanaloge

Country Status (16)

Country	Link
US (1)	US5484775A (de)
EP (1)	EP0410881B1 (de)
JP (1)	JPH0358995A (de)
KR (1)	KR910002887A (de)
AT (1)	ATE158297T1 (de)
AU (1)	AU5982990A (de)
CA (1)	CA2022138A1 (de)
DE (1)	DE69031448T2 (de)
ES (1)	ES2106025T3 (de)
FI (1)	FI903753A7 (de)
HU (1)	HU210923B (de)
IL (1)	IL95169A0 (de)
IT (1)	IT1232175B (de)
NO (1)	NO903333L (de)
NZ (1)	NZ234649A (de)
PL (1)	PL165209B1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1232176B (it) *	1989-07-27	1992-01-25	Fidia Farmaceutici	Derivati di-lisogangliosidi
IT1239060B (it) *	1990-05-04	1993-09-20	Fidia Spa	Processo per la modulazione selettiva dell'espressione e della funzione di un determinante sulla superficie cellulare attraverso appropriati agenti chimici
IT1253832B (it) *	1991-08-01	1995-08-29	Fidia Spa	Derivati di gangliosidi
DE4204907A1 (de) *	1992-02-14	1993-08-19	Reutter Werner	Neuartige glykokonjugate mit n-substituierten neuraminsaeuren als mittel zur stimulierung des immunsystems
MXPA04001831A (es)	2001-08-29	2004-07-08	Neose Technologies Inc	Nuevos derivados sinteticos de gangliosidos y composiciones de los mismos.
NZ567841A (en)	2003-03-06	2010-01-29	Seneb Biosciences Inc	Methods and compositions for the enzymatic synthesis of gangliosides
WO2010111530A1 (en)	2009-03-25	2010-09-30	Seneb Biosciences, Inc.	Glycolipids as treatment for disease
PE20181031A1 (es)	2015-10-09	2018-06-27	Tensar Corp Llc	Geomalla hecha a partir de un polimero estratificado coextruido

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4476119A (en) *	1981-08-04	1984-10-09	Fidia S.P.A.	Method for preparing ganglioside derivatives and use thereof in pharmaceutical compositions
US4593091A (en) *	1981-08-04	1986-06-03	Fidia, S.P.A.	Method for preparing ganglioside derivatives and use thereof in pharmaceutical compositions
US4716223A (en) *	1981-08-04	1987-12-29	Fidia, S.P.A.	Method for preparing ganglioside derivatives and use thereof in pharmaceutical compositions
IT1199116B (it) *	1984-07-03	1988-12-30	Fidia Farmaceutici	Derivati di gangliosidi
JPH06795B2 (ja) *	1985-04-02	1994-01-05	理化学研究所	アシアロガングリオシド関連化合物の製造方法
DE3852526D1 (de) *	1987-06-26	1995-02-02	Solco Basel Ag	Neue pharmazeutische Präparate sowie neue Lactosylverbindungen und ihre Herstellung.
IT1212041B (it) *	1987-11-02	1989-11-08	Fidia Farmaceutici	Gangliosidi esteri interni come agenti terapeutici capaci di eliminare il dolore nelle neuropatie periferiche
CA1339488C (en) *	1988-02-12	1997-10-07	Taeko Dohi	De-n-acetyl-syalic acid and their applications as modifiers of cell physiology
IT1235161B (it) *	1988-12-02	1992-06-22	Fidia Farmaceutici	Derivati di lisogangliosidi
IT1253832B (it) *	1991-08-01	1995-08-29	Fidia Spa	Derivati di gangliosidi

1989
- 1989-07-27 IT IT8948246A patent/IT1232175B/it active
1990
- 1990-07-24 IL IL95169A patent/IL95169A0/xx unknown
- 1990-07-25 DE DE69031448T patent/DE69031448T2/de not_active Expired - Fee Related
- 1990-07-25 ES ES90402139T patent/ES2106025T3/es not_active Expired - Lifetime
- 1990-07-25 AU AU59829/90A patent/AU5982990A/en not_active Abandoned
- 1990-07-25 NZ NZ234649A patent/NZ234649A/en unknown
- 1990-07-25 AT AT90402139T patent/ATE158297T1/de active
- 1990-07-25 EP EP90402139A patent/EP0410881B1/de not_active Expired - Lifetime
- 1990-07-26 HU HU904640A patent/HU210923B/hu not_active IP Right Cessation
- 1990-07-26 NO NO90903333A patent/NO903333L/no unknown
- 1990-07-27 JP JP2201059A patent/JPH0358995A/ja active Pending
- 1990-07-27 CA CA002022138A patent/CA2022138A1/en not_active Abandoned
- 1990-07-27 PL PL90286249A patent/PL165209B1/pl unknown
- 1990-07-27 FI FI903753A patent/FI903753A7/fi not_active Application Discontinuation
- 1990-07-27 KR KR1019900011755A patent/KR910002887A/ko not_active Withdrawn
1993
- 1993-07-26 US US08/096,853 patent/US5484775A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US5484775A (en)	1996-01-16
HU210923B (en)	1995-09-28
FI903753A7 (fi)	1991-01-28
FI903753A0 (fi)	1990-07-27
AU5982990A (en)	1991-01-31
EP0410881B1 (de)	1997-09-17
IL95169A0 (en)	1991-06-10
HUT54173A (en)	1991-01-28
EP0410881A3 (en)	1993-01-20
NO903333D0 (no)	1990-07-26
PL165209B1 (pl)	1994-11-30
HU904640D0 (en)	1991-01-28
IT8948246A0 (it)	1989-07-27
CA2022138A1 (en)	1991-01-28
PL286249A1 (en)	1991-08-26
DE69031448T2 (de)	1998-02-26
JPH0358995A (ja)	1991-03-14
EP0410881A2 (de)	1991-01-30
KR910002887A (ko)	1991-02-26
NO903333L (no)	1991-01-28
IT1232175B (it)	1992-01-25
ES2106025T3 (es)	1997-11-01
NZ234649A (en)	1992-01-29
DE69031448D1 (de)	1997-10-23

Publication	Publication Date	Title
HUP0001640A2 (hu)	2001-05-28	N6-helyzetben heterociklusosan szubsztituált adenozinszármazékok, alkalmazásuk gyógyszerkészítmények előállítására és ezeket tartalmazó gyógyszerkészítmények
IT1220419B (it)	1990-06-15	Cassetto per mobili
NZ231590A (en)	1992-12-23	N-acyllysosphingolipids and pharmaceutical compositions thereof
ATE158297T1 (de)	1997-10-15	Halbsynthetische gangliosidanaloge
EP0973518A4 (de)	2004-05-26	Semisynthetisches verfahren zur herstellung von didemninanalogen
FR2379549A1 (fr)	1978-09-01	4''-deoxy-4''-(amino substitue)-oleandomycines et medicament les contenant
DE69033027D1 (de)	1999-05-06	Di-lysogangliosidderivate
DE68914418D1 (de)	1994-05-11	Lysoganglioside-Derivate.
IL83967A (en)	1992-11-15	Pharmaceutical compositions comprising antigestagens for the inhibition of uterine synthesis of prostaglandin
IT8606741V0 (it)	1986-09-30	Cassetto per mobili.
IT215627Z2 (it)	1990-10-18	Elemento di raccordo per frontali di mobili.
IT1225035B (it)	1990-11-02	Supporto incassabile perfezionato per il fissagio di ripiani di mobili
DK587585D0 (da)	1985-12-17	13 alfa-alkyl-17 beta-(3-acyloxypropyl)-gonaner, fremgangsmaade til fremstilling heraf samt farmaceutiske praeparater indeholdende disse forbindelser
DZ1230A1 (fr)	2004-09-13	Procédé de préparation des cis-n-(3-méthoxy-4-pipéridinyl benzamides.