ATE160773T1 - Kondensierte tricyclische heteroaromatische verbindungen als dopamin-rezeptor-subtyp-liganden - Google Patents
Kondensierte tricyclische heteroaromatische verbindungen als dopamin-rezeptor-subtyp-ligandenInfo
- Publication number
- ATE160773T1 ATE160773T1 AT94925560T AT94925560T ATE160773T1 AT E160773 T1 ATE160773 T1 AT E160773T1 AT 94925560 T AT94925560 T AT 94925560T AT 94925560 T AT94925560 T AT 94925560T AT E160773 T1 ATE160773 T1 AT E160773T1
- Authority
- AT
- Austria
- Prior art keywords
- dopamine receptor
- heteroaromatic compounds
- pct
- receptor subtype
- tricyclic heteroaromatic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939318691A GB9318691D0 (en) | 1993-09-09 | 1993-09-09 | Therapeutic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE160773T1 true ATE160773T1 (de) | 1997-12-15 |
Family
ID=10741750
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94925560T ATE160773T1 (de) | 1993-09-09 | 1994-09-06 | Kondensierte tricyclische heteroaromatische verbindungen als dopamin-rezeptor-subtyp-liganden |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5686480A (de) |
| EP (1) | EP0717733B1 (de) |
| JP (1) | JPH09502199A (de) |
| AT (1) | ATE160773T1 (de) |
| AU (1) | AU684304B2 (de) |
| CA (1) | CA2168738A1 (de) |
| DE (1) | DE69407191T2 (de) |
| ES (1) | ES2110256T3 (de) |
| GB (1) | GB9318691D0 (de) |
| WO (1) | WO1995007262A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19519056A1 (de) * | 1995-05-24 | 1997-01-16 | Klinge Co Chem Pharm Fab | Verwendung von Antidepressiva zur Behandlung von Asthma und/oder Atemwegserkrankungen mittels inhalatorischer Applikation |
| US6187774B1 (en) * | 1996-03-04 | 2001-02-13 | Yoshitomi Pharmaceutical Industries, Ltd. | Fused heterocyclic compounds and pharmaceutical applications thereof |
| WO2000012500A2 (en) * | 1998-09-02 | 2000-03-09 | Neurogen Corporation | 2-aryl-4-(1-[4-heteroaryl]piperazin-1-yl) methylimidazoles: dopamine d4 receptor subtype ligands |
| US6107313A (en) * | 1998-10-02 | 2000-08-22 | Combichem, Inc. | Dopamine receptor antagonists |
| US6462036B1 (en) * | 1998-11-06 | 2002-10-08 | Basf Aktiengesellschaft | Tricyclic pyrazole derivatives |
| BR0212611A (pt) * | 2001-09-19 | 2004-08-17 | Pharmacia Corp | Compostos de pirazolila substituìdos para o tratamento da inflamação |
| AR040967A1 (es) * | 2002-08-12 | 2005-04-27 | Janssen Pharmaceutica Nv | Derivados de isoxazolina triciclicos c- sustituidos y su uso como anti- depresivos |
| CN1303085C (zh) * | 2002-08-21 | 2007-03-07 | 詹森药业有限公司 | C6－和c9－取代的异噁唑啉衍生物和它们作为抗抑郁药的用途 |
| KR101107800B1 (ko) | 2006-10-31 | 2012-01-25 | 화이자 프로덕츠 인코포레이티드 | 무기질코르티코이드 수용체 길항제로서의 피라졸린 화합물 |
| AU2008249745B2 (en) * | 2007-05-09 | 2012-01-12 | Pfizer Inc. | Substituted heterocyclic derivatives and compositions and their pharmaceutical use as antibacterials |
| WO2010049366A1 (en) * | 2008-10-27 | 2010-05-06 | Glaxo Group Limited | Tricyclic compounds as glutamate receptor modulators |
| DE102010055499A1 (de) * | 2010-12-22 | 2011-06-16 | W.C. Heraeus Gmbh | Prozess zur Herstellung von Bendamustinalkylester, Bendarmustin sowie Derivaten davon |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3553230A (en) * | 1967-09-26 | 1971-01-05 | Colgate Palmolive Co | 3-aminoalkyl and 3-amino derivatives of 4h(1)benzopyrano(3,4-d)isoxazoles |
| US3969527A (en) * | 1975-07-28 | 1976-07-13 | E. R. Squibb & Sons, Inc. | CNS active compounds |
| DK0402644T3 (da) * | 1989-05-19 | 1996-01-02 | Hoechst Roussel Pharma | N-(Aryloxyalkyl)-heteroarylpiperidiner og -heteroarylpiperaziner, fremgangsmåde til deres fremstilli ng samt deres anvendelse som medikamenter |
| CA2146018A1 (en) * | 1992-10-23 | 1994-05-11 | Paul David Leeson | Dopamine receptor subtype ligands |
-
1993
- 1993-09-09 GB GB939318691A patent/GB9318691D0/en active Pending
-
1994
- 1994-09-06 EP EP94925560A patent/EP0717733B1/de not_active Expired - Lifetime
- 1994-09-06 DE DE69407191T patent/DE69407191T2/de not_active Expired - Fee Related
- 1994-09-06 WO PCT/GB1994/001935 patent/WO1995007262A1/en not_active Ceased
- 1994-09-06 ES ES94925560T patent/ES2110256T3/es not_active Expired - Lifetime
- 1994-09-06 AT AT94925560T patent/ATE160773T1/de not_active IP Right Cessation
- 1994-09-06 CA CA002168738A patent/CA2168738A1/en not_active Abandoned
- 1994-09-06 JP JP7508528A patent/JPH09502199A/ja active Pending
- 1994-09-06 US US08/605,096 patent/US5686480A/en not_active Expired - Fee Related
- 1994-09-06 AU AU75425/94A patent/AU684304B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DE69407191T2 (de) | 1998-07-02 |
| EP0717733A1 (de) | 1996-06-26 |
| ES2110256T3 (es) | 1998-02-01 |
| AU684304B2 (en) | 1997-12-11 |
| DE69407191D1 (de) | 1998-01-15 |
| AU7542594A (en) | 1995-03-27 |
| EP0717733B1 (de) | 1997-12-03 |
| GB9318691D0 (en) | 1993-10-27 |
| WO1995007262A1 (en) | 1995-03-16 |
| US5686480A (en) | 1997-11-11 |
| CA2168738A1 (en) | 1995-03-16 |
| JPH09502199A (ja) | 1997-03-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2121193T3 (es) | Derivados de bencimidazoles. | |
| GB9306578D0 (en) | Therapeutic agents | |
| ATE174591T1 (de) | Kondensierte tricyclische heteroaromatische derivate als liganden des dopamin-rezeptor- subtyps | |
| ATE160773T1 (de) | Kondensierte tricyclische heteroaromatische verbindungen als dopamin-rezeptor-subtyp-liganden | |
| DE69325662D1 (de) | Dopamin rezeptor subtyp liganden | |
| DE69420637D1 (de) | Tricyclische Derivate und ihre Anwendung als Krebsmittel | |
| ES2110225T3 (es) | Derivados antisicoticos de indazol. | |
| NZ519241A (en) | Tricyclic fused heterocyclic compound, process for preparing it and medicament comprising it | |
| BR9709501A (pt) | Composto, composição farmacêutica , e, processos para tratar ou prevenir a esquizofrrenia e para sintetizar um composto | |
| UA72881C2 (uk) | Похідні тієнопіридину, фармацевтична композиція з використанням таких сполук (варіанти), проміжна сполука | |
| TNSN97192A1 (fr) | Derives de pyrimidine bicycliques condenses, procede pour leur preparation et compositions pharmaceutiques les contenant. | |
| WO1994020459A3 (en) | Pyrrolo-pyridine derivatives as dopamine receptor ligands | |
| GB9305641D0 (en) | Therapeutic agents | |
| FI964340A0 (fi) | Uudet asykliset ja sykliset amidit hermoston välittäjäaineen vapautumisen tehostimina | |
| TW342385B (en) | Bicyclic benzazepin, the process for their preparation and the pharmaceutical composition containing them | |
| DE69515177D1 (de) | Tetrahydropyridinylmethylderivate von pyrrolo[2,3-b]pyridine | |
| HU9301250D0 (en) | Application of 5-ht la-receptor antagonists or partial agonists thereof for treating or preventing distrubations of cognition | |
| IL115384A (en) | 2,7-Substituted octahydro-1h-pyrido [1,2-a]pyrazine derivatives and pharmaceutical compositions containing them | |
| EP0845988A4 (de) | Neue kondensierten isochinoline als dopamin-rezeptor-liganden | |
| IL100458A0 (en) | Pharmaceutical compositions containing antagonists of the quisqualate receptor | |
| NZ334553A (en) | N-(2-Benzothiazolyl) piperidine-1 ethanamine derivatives and pharmaceutical use | |
| DE69407607D1 (de) | Imidanolon- und oxanolonderivate als dopaminantagonisten | |
| ATE189894T1 (de) | Naphthamidderivate von 3-beta-amino azabicyclooctan oder nonan als antipsychotische arzneimittel | |
| TNSN99104A1 (fr) | 3 - cetoderives tricycliques de 6 - 0 - methylerythromycine, procede pour leur preparation et compositions pharmaceutiques les contenant | |
| DK0766695T3 (da) | Pyrrolidinderivater til behandling af CCK- og gastrinrelaterede sygdomme |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |