ATE160773T1 - Kondensierte tricyclische heteroaromatische verbindungen als dopamin-rezeptor-subtyp-liganden - Google Patents
Kondensierte tricyclische heteroaromatische verbindungen als dopamin-rezeptor-subtyp-ligandenInfo
- Publication number
- ATE160773T1 ATE160773T1 AT94925560T AT94925560T ATE160773T1 AT E160773 T1 ATE160773 T1 AT E160773T1 AT 94925560 T AT94925560 T AT 94925560T AT 94925560 T AT94925560 T AT 94925560T AT E160773 T1 ATE160773 T1 AT E160773T1
- Authority
- AT
- Austria
- Prior art keywords
- dopamine receptor
- heteroaromatic compounds
- pct
- receptor subtype
- tricyclic heteroaromatic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939318691A GB9318691D0 (en) | 1993-09-09 | 1993-09-09 | Therapeutic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE160773T1 true ATE160773T1 (de) | 1997-12-15 |
Family
ID=10741750
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94925560T ATE160773T1 (de) | 1993-09-09 | 1994-09-06 | Kondensierte tricyclische heteroaromatische verbindungen als dopamin-rezeptor-subtyp-liganden |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5686480A (de) |
| EP (1) | EP0717733B1 (de) |
| JP (1) | JPH09502199A (de) |
| AT (1) | ATE160773T1 (de) |
| AU (1) | AU684304B2 (de) |
| CA (1) | CA2168738A1 (de) |
| DE (1) | DE69407191T2 (de) |
| ES (1) | ES2110256T3 (de) |
| GB (1) | GB9318691D0 (de) |
| WO (1) | WO1995007262A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19519056A1 (de) * | 1995-05-24 | 1997-01-16 | Klinge Co Chem Pharm Fab | Verwendung von Antidepressiva zur Behandlung von Asthma und/oder Atemwegserkrankungen mittels inhalatorischer Applikation |
| US6187774B1 (en) * | 1996-03-04 | 2001-02-13 | Yoshitomi Pharmaceutical Industries, Ltd. | Fused heterocyclic compounds and pharmaceutical applications thereof |
| WO2000012500A2 (en) * | 1998-09-02 | 2000-03-09 | Neurogen Corporation | 2-aryl-4-(1-[4-heteroaryl]piperazin-1-yl) methylimidazoles: dopamine d4 receptor subtype ligands |
| US6107313A (en) * | 1998-10-02 | 2000-08-22 | Combichem, Inc. | Dopamine receptor antagonists |
| US6462036B1 (en) | 1998-11-06 | 2002-10-08 | Basf Aktiengesellschaft | Tricyclic pyrazole derivatives |
| WO2003024935A2 (en) * | 2001-09-19 | 2003-03-27 | Pharmacia Corporation | Substituted pyrazolyl compounds for the treatment of inflammation |
| AR040967A1 (es) * | 2002-08-12 | 2005-04-27 | Janssen Pharmaceutica Nv | Derivados de isoxazolina triciclicos c- sustituidos y su uso como anti- depresivos |
| US7462717B2 (en) | 2002-08-21 | 2008-12-09 | Janssen Pharmaceutica N.V. | C6-and C9-substituted chromeno[4,3-c]isoxazoline derivatives and their use as anti-depressants |
| AP2527A (en) | 2006-10-31 | 2012-12-06 | Pfizer Prod Inc | Pyrazoline compounds as mineralocorticoid receptorantagonists |
| AU2008249745B2 (en) * | 2007-05-09 | 2012-01-12 | Pfizer Inc. | Substituted heterocyclic derivatives and compositions and their pharmaceutical use as antibacterials |
| US20110263588A1 (en) * | 2008-10-27 | 2011-10-27 | Glaxo Group Limited | Tricyclic compounds as glutamate receptor modulators |
| DE102010055499A1 (de) * | 2010-12-22 | 2011-06-16 | W.C. Heraeus Gmbh | Prozess zur Herstellung von Bendamustinalkylester, Bendarmustin sowie Derivaten davon |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3553230A (en) * | 1967-09-26 | 1971-01-05 | Colgate Palmolive Co | 3-aminoalkyl and 3-amino derivatives of 4h(1)benzopyrano(3,4-d)isoxazoles |
| US3969527A (en) * | 1975-07-28 | 1976-07-13 | E. R. Squibb & Sons, Inc. | CNS active compounds |
| ES2076253T3 (es) * | 1989-05-19 | 1995-11-01 | Hoechst Roussel Pharma | N-(ariloxialquil)-heteroarilpiperidinas y -heteroarilpiperazinas, un procedimiento para su preparacion y su uso como medicamentos. |
| JPH08502958A (ja) * | 1992-10-23 | 1996-04-02 | メルク シヤープ エンド ドーム リミテツド | ドーパミンレセプターサブタイプリガンド |
-
1993
- 1993-09-09 GB GB939318691A patent/GB9318691D0/en active Pending
-
1994
- 1994-09-06 AT AT94925560T patent/ATE160773T1/de not_active IP Right Cessation
- 1994-09-06 US US08/605,096 patent/US5686480A/en not_active Expired - Fee Related
- 1994-09-06 ES ES94925560T patent/ES2110256T3/es not_active Expired - Lifetime
- 1994-09-06 EP EP94925560A patent/EP0717733B1/de not_active Expired - Lifetime
- 1994-09-06 DE DE69407191T patent/DE69407191T2/de not_active Expired - Fee Related
- 1994-09-06 AU AU75425/94A patent/AU684304B2/en not_active Ceased
- 1994-09-06 JP JP7508528A patent/JPH09502199A/ja active Pending
- 1994-09-06 CA CA002168738A patent/CA2168738A1/en not_active Abandoned
- 1994-09-06 WO PCT/GB1994/001935 patent/WO1995007262A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AU684304B2 (en) | 1997-12-11 |
| WO1995007262A1 (en) | 1995-03-16 |
| EP0717733B1 (de) | 1997-12-03 |
| ES2110256T3 (es) | 1998-02-01 |
| DE69407191T2 (de) | 1998-07-02 |
| EP0717733A1 (de) | 1996-06-26 |
| JPH09502199A (ja) | 1997-03-04 |
| CA2168738A1 (en) | 1995-03-16 |
| DE69407191D1 (de) | 1998-01-15 |
| AU7542594A (en) | 1995-03-27 |
| US5686480A (en) | 1997-11-11 |
| GB9318691D0 (en) | 1993-10-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |