ATE160787T1 - Verfahren zur herstellung von hefe-glucanen - Google Patents

Verfahren zur herstellung von hefe-glucanen

Info

Publication number
ATE160787T1
ATE160787T1 AT91111143T AT91111143T ATE160787T1 AT E160787 T1 ATE160787 T1 AT E160787T1 AT 91111143 T AT91111143 T AT 91111143T AT 91111143 T AT91111143 T AT 91111143T AT E160787 T1 ATE160787 T1 AT E160787T1
Authority
AT
Austria
Prior art keywords
provides
stimulating
administering
glucanes
glucan
Prior art date
Application number
AT91111143T
Other languages
English (en)
Inventor
Gunnar Rorstad
Borre Robertson
Jan Raa
Original Assignee
Biotec Mackzymal As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotec Mackzymal As filed Critical Biotec Mackzymal As
Application granted granted Critical
Publication of ATE160787T1 publication Critical patent/ATE160787T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/062—Ascomycota
    • A61K36/064—Saccharomycetales, e.g. baker's yeast
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Mycology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Farming Of Fish And Shellfish (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT91111143T 1990-07-06 1991-07-04 Verfahren zur herstellung von hefe-glucanen ATE160787T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US54957590A 1990-07-06 1990-07-06

Publications (1)

Publication Number Publication Date
ATE160787T1 true ATE160787T1 (de) 1997-12-15

Family

ID=24193557

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91111143T ATE160787T1 (de) 1990-07-06 1991-07-04 Verfahren zur herstellung von hefe-glucanen

Country Status (12)

Country Link
US (1) US5401727A (de)
EP (1) EP0466037B1 (de)
JP (1) JP2828799B2 (de)
AT (1) ATE160787T1 (de)
AU (1) AU628752B2 (de)
CA (1) CA2040374C (de)
DE (1) DE69128308T2 (de)
DK (1) DK0466037T3 (de)
ES (1) ES2109929T3 (de)
FI (1) FI104537B (de)
GR (1) GR3026130T3 (de)
NO (1) NO305705B1 (de)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0665649B2 (ja) * 1991-02-01 1994-08-24 台糖株式会社 甲殻類の生体防御能増強剤、感染症予防ワクチン及び飼料
JP3522772B2 (ja) * 1991-05-21 2004-04-26 台糖株式会社 ワクチンの免疫効果増強剤
EP0640348A1 (de) * 1993-07-26 1995-03-01 Akzo Nobel N.V. Adjuvansmischung auf Ölbasis und auf Wasserbasis
WO1995004467A1 (en) * 1993-08-06 1995-02-16 A/S Biotec-Mackzymal Animal feeds comprising yeast glucan
JPH08113539A (ja) * 1993-09-22 1996-05-07 Nippon Paper Ind Co Ltd 免疫増強剤及びその製造方法、並びにそれを用いた甲殻類及び魚類の養殖用飼料
NO300692B1 (no) * 1994-04-29 1997-07-07 Biotec Mackzymal As Solubilisert forgrenet ß-1,3-glukan og anvendelse derav samt anvendelse av usolubilisert forgrenet ß-1,3-glukan
US5871751A (en) * 1994-10-12 1999-02-16 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Renibacterium salmoninarum vaccine and method for its preparation
JP3744020B2 (ja) * 1995-04-14 2006-02-08 日本製紙株式会社 免疫増強剤並びにそれを含有する甲殻類、魚類及び家畜用飼料
DE59606099D1 (de) * 1995-09-05 2000-12-07 Baensch Tetra Werke Antistressmittel für wassertiere
US5722346A (en) * 1996-04-17 1998-03-03 The Board Of Governors For Higher Education Smolting feed
US5786343A (en) * 1997-03-05 1998-07-28 Immudyne, Inc. Phagocytosis activator compositions and their use
AU6691598A (en) * 1997-04-18 1998-11-13 Immudyne, Inc. Gel delivery system for animal nutrition and health
US7030101B2 (en) 1998-09-14 2006-04-18 Nabi Biopharmaceuticals Compositions of β-glucans and specific antibodies
ES2321892T3 (es) * 1998-09-14 2009-06-12 Nabi Biopharmaceuticals Composiciones de beta-glucanos e inmunoglobulinas especificas.
US20020009463A1 (en) * 2000-02-23 2002-01-24 Jan Raa Novel, non-antigenic, mucosal adjuvant formulation which enhances the effects of substances, including vaccine antigens, in contact with mucosal body surfaces
US20040127458A1 (en) * 2000-11-06 2004-07-01 Hunter Kenneth W. Beta-glucan containing compositions, methods for manufacturing beta-glucans, and for manufacturing and using beta-glucans and conjugates thereof as vaccine adjuvants
US8222232B2 (en) * 2001-02-16 2012-07-17 Cargill, Incorporated Glucosamine and N-acetylglucosamine compositions and methods of making the same fungal biomass
US7923437B2 (en) * 2001-02-16 2011-04-12 Cargill, Incorporated Water soluble β-glucan, glucosamine, and N-acetylglucosamine compositions and methods for making the same
US7816514B2 (en) 2001-02-16 2010-10-19 Cargill, Incorporated Glucosamine and method of making glucosamine from microbial biomass
US7323140B2 (en) * 2001-03-28 2008-01-29 Handylab, Inc. Moving microdroplets in a microfluidic device
US6939864B1 (en) 2001-07-09 2005-09-06 Purdue Research Foundation Animal feed compositions and methods of using the same
CN1596116A (zh) * 2001-11-06 2005-03-16 东方癌症治疗株式会社 抗癌组合物
DE10222358A1 (de) * 2002-05-21 2003-12-11 Nutrinova Gmbh ß-Glucanhaltiges Sorbinsäurepräparat als Futtermittelzusatz in der Nutztieraufzucht
US7018986B2 (en) * 2002-09-20 2006-03-28 Immudyne Use of beta glucans for the treatment of osteoporosis and other diseases of bone resorption
GB0225502D0 (en) * 2002-11-01 2002-12-11 Zoolife Internat Ltd Therapeutic and prophylactic preparations
GB0225503D0 (en) * 2002-11-01 2002-12-11 Zoolife Internat Ltd Gel feed
JP2004210895A (ja) * 2002-12-27 2004-07-29 Immudyne Japan:Kk 免疫機能を有する可能性β−グルカンの製造方法及び用途
JP2007524354A (ja) * 2003-01-29 2007-08-30 イミュダイン インコーポレーティッド 動物用の免疫増強剤
GB2399752A (en) * 2003-03-26 2004-09-29 Micap Plc Pharmaceutical composition comprising a fungal cell or cell fragment as adjuvant
PT3659437T (pt) 2004-01-23 2022-06-20 Eden Research Plc Métodos para matar nemátodos que compreendem a aplicação de um componente terpeno encapsulado
EP2338332B1 (de) 2004-05-20 2014-02-12 Eden Research Plc Hohles glukan- oder zellenwand-partikel, das eine terpenkomponente verkapselt
US7740861B2 (en) * 2004-06-16 2010-06-22 University Of Massachusetts Drug delivery product and methods
AU2005284727A1 (en) * 2004-09-17 2006-03-23 University Of Massachusetts Compositions and their uses for lysosomal enzyme deficiencies
US7306818B2 (en) * 2005-01-03 2007-12-11 Promd Biotech Co., Ltd. Method for preventing and/or treating viral infection in aquatic animals
MX2007013725A (es) 2005-05-05 2008-04-09 Sensient Flavors Inc Produccion de beta-glucanos y mananos.
ATE526991T1 (de) * 2005-10-24 2011-10-15 Univ Massachusetts Zusammensetzungen und ihre verwendungen für die gentherapeutische behandlung von knochenerkrankungen
JP6027718B2 (ja) 2005-11-30 2016-11-16 エーデン リサーチ ピーエルシー チモール、オイゲノール、ゲラニオール、シトラール、及びｌ−カルボンから選択されたテルペン又はテルペン混合物を含む組成物及び方法
EP2982244B1 (de) 2005-11-30 2020-11-18 Eden Research Plc Thymolhaltige Insektizide Kapseln und Verfahren zu ihrer Herstellung und Verwendung
TW200900053A (en) * 2007-02-21 2009-01-01 Biotec Pharmacon Asa Medical uses of glucans
JP5153188B2 (ja) * 2007-03-30 2013-02-27 小林製薬株式会社 Ｔｈ１／Ｔｈ２バランス改善剤
US20090061049A1 (en) * 2007-08-28 2009-03-05 Vadood Azarm Feed compositions for aquatic animals and methods of making the same
EP2222283A2 (de) * 2007-10-29 2010-09-01 University of Massachusetts Zur freisetzung von nukleinsäuren (sirna) mit hefe-zellwandproteinen verkapselte mehrlagige nanopatikel
JP2011503161A (ja) * 2007-11-13 2011-01-27 バイオテック・ファルマコン・アーエスアー 腸管の炎症性疾患を処置または予防する方法
CA2705544A1 (en) 2007-11-19 2009-05-28 Calanus As Bioactive copepod-compositions, processes for the production thereof, and use thereof to prevent or treat hosts infested by phylogenetically similar ectoparasites
US8815818B2 (en) 2008-07-18 2014-08-26 Rxi Pharmaceuticals Corporation Phagocytic cell delivery of RNAI
WO2010078536A1 (en) 2009-01-05 2010-07-08 Rxi Pharmaceuticals Corporation Inhibition of pcsk9 through rnai
US20100267661A1 (en) * 2009-03-17 2010-10-21 Immudyne, Inc. Beta glucans and methods of use thereof
EP3560503B1 (de) 2010-03-24 2021-11-17 Phio Pharmaceuticals Corp. Rna-interferenz bei dermalen und fibrotischen erkrankungen
CN103200945B (zh) 2010-03-24 2016-07-06 雷克西制药公司 眼部症候中的rna干扰
EP2603450B1 (de) 2010-08-14 2016-11-02 University of Massachusetts Wandpartikel aus hefezellen für rezeptorengerichtete nanopartikelfreisetzung
EP2694030A2 (de) 2011-03-04 2014-02-12 Sana Pharma AS Kosmetische formulierungen
GB201220940D0 (en) 2012-11-21 2013-01-02 Eden Research Plc Method P
EP3071031A1 (de) 2013-11-21 2016-09-28 Eden Research Plc Pestizidzusammensetzung
CN105960265A (zh) 2013-12-04 2016-09-21 阿克赛医药公司 利用经化学修饰的寡核苷酸处理伤口愈合的方法
WO2015168108A2 (en) 2014-04-28 2015-11-05 Rxi Pharmaceuticals Corporation Methods for treating cancer using nucleic targeting mdm2 or mycn
JP2017514908A (ja) 2014-05-01 2017-06-08 アールエックスアイ ファーマシューティカルズ コーポレーション 核酸分子を利用する目の前部における障害の処置のための方法
US10900039B2 (en) 2014-09-05 2021-01-26 Phio Pharmaceuticals Corp. Methods for treating aging and skin disorders using nucleic acids targeting Tyr or MMP1
JP2018504380A (ja) 2014-12-18 2018-02-15 アルナイラム ファーマシューティカルズ， インコーポレイテッドＡｌｎｙｌａｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． Ｒｅｖｅｒｓｉｒ（商標）化合物
GB201501793D0 (en) 2015-02-03 2015-03-18 Eden Research Plc Encapsulation of high potency active agents
US10808247B2 (en) 2015-07-06 2020-10-20 Phio Pharmaceuticals Corp. Methods for treating neurological disorders using a synergistic small molecule and nucleic acids therapeutic approach
EP3862005A1 (de) 2015-07-06 2021-08-11 Phio Pharmaceuticals Corp. Gegen superoxid-dismutase 1 (sod1) gerichtete nukleinsäuremoleküle
EP3138573A1 (de) * 2015-07-09 2017-03-08 Danstar Ferment AG Zusammensetzungen und verfahren zur stimulation der immunantwort in menschen und/oder tieren
WO2017070151A1 (en) 2015-10-19 2017-04-27 Rxi Pharmaceuticals Corporation Reduced size self-delivering nucleic acid compounds targeting long non-coding rna
CN106719136A (zh) * 2016-11-30 2017-05-31 蚌埠市渔歌农业科技有限公司 一种防治鲶鱼病害的养殖方法
US12544344B2 (en) 2017-04-19 2026-02-10 Phio Pharmaceuticals Corp. Topical delivery of nucleic acid compounds
JP6530846B1 (ja) * 2018-10-09 2019-06-12 アサヒグループホールディングス株式会社 免疫賦活剤及び感染予防方法
CN115135765A (zh) 2019-11-08 2022-09-30 菲奥医药公司 用于免疫治疗的靶向含布罗莫结构域之蛋白4(brd4)的经化学修饰的寡核苷酸
AU2022278209A1 (en) * 2021-05-21 2023-11-09 Asahi Group Holdings, Ltd. Immunostimulator and glucan composition production method
TW202449152A (zh) 2023-02-09 2024-12-16 美商艾拉倫製藥股份有限公司 Ｒｅｖｅｒｓｉｒ分子及其使用方法
WO2025078537A1 (en) 2023-10-10 2025-04-17 Ab Mauri (Uk) Ltd Compositions comprising branched (1,3)(1,6)-beta-glucans for use in the treatment of cancer
WO2025078523A1 (en) 2023-10-10 2025-04-17 Ab Mauri (Uk) Ltd Compositions comprising a combination of (1,3)(1,6)-beta-glucans and uses thereof in therapy

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3301848A (en) * 1962-10-30 1967-01-31 Pillsbury Co Polysaccharides and methods for production thereof
GB2076418A (en) * 1980-05-22 1981-12-02 Sankyo Co Hydrolyzed polysaccharide
SE456911B (sv) * 1983-12-19 1988-11-14 Olle Larm Vattenloeslig, aminerad beta-1,3-bunden d-glukan och makrofagstimulerande komposition innehaallande densamma
JPS6120561A (ja) * 1984-07-09 1986-01-29 住友ベークライト株式会社 医療用吸着剤
US4810646A (en) * 1984-11-28 1989-03-07 Massachusetts Institute Of Technology Glucan compositions and process for preparation thereof
US4739046A (en) * 1985-08-19 1988-04-19 Luzio Nicholas R Di Soluble phosphorylated glucan
JPS6337801A (ja) * 1986-07-31 1988-02-18 Matsushita Electric Ind Co Ltd タ−ンテ−ブル
CA1330303C (en) * 1989-02-20 1994-06-21 Libor Henry Nikl Composition and process to enhance the efficacy of a fish vaccine

Also Published As

Publication number Publication date
NO912645D0 (no) 1991-07-05
DE69128308T2 (de) 1998-03-26
GR3026130T3 (en) 1998-05-29
CA2040374C (en) 1998-06-16
JP2828799B2 (ja) 1998-11-25
CA2040374A1 (en) 1992-01-07
DE69128308D1 (de) 1998-01-15
ES2109929T3 (es) 1998-02-01
DK0466037T3 (da) 1998-08-10
FI104537B (fi) 2000-02-29
NO305705B1 (no) 1999-07-12
EP0466037A3 (en) 1992-10-28
FI913275L (fi) 1992-01-07
NO912645L (no) 1992-01-07
EP0466037B1 (de) 1997-12-03
AU7933891A (en) 1992-01-23
FI913275A0 (fi) 1991-07-05
JPH04253703A (ja) 1992-09-09
AU628752B2 (en) 1992-09-17
EP0466037A2 (de) 1992-01-15
US5401727A (en) 1995-03-28

Similar Documents

Publication Publication Date Title
ATE160787T1 (de) Verfahren zur herstellung von hefe-glucanen
DE69637481D1 (de) Aus immunisierten Xenomäusen stammende menschliche Antikörper gegen IL-8
EP0438803A3 (en) Vaccines against cancer and infectious diseases
BR9809656A (pt) Composição imunopotencializante
ATE272409T1 (de) Verfahren zur erzeugung aktiver immunität durch vakzinkonjugate
ATE150976T1 (de) Impfstoff-konjugate zur behandlung von vogelkrankheiten
GR3029774T3 (en) Method of preparing a radioactive rhenium complex solution.
ATE166230T1 (de) Verwendung von anti-icam antikörpern zur herstellung eines präparats für die behandlung von endotoxinschock
EP0716613A4 (de) BEHANDLUNG EINES DURCH -i(HELICOBAKTER PYLORI) VERURSACHTEN GASTRODUODENALEN KRANKHEIT
DE69034264D1 (de) Verfahren zur Herstellung eines azellulären Impfstoffes der Bordetella pertussis Antigene enthält
DE69030099D1 (de) Verfahren zur herstellung von impfstoffen oder toxoiden
DE69333730D1 (de) Impfstoff, der acemannan als adjuvans enthält
DE69019086D1 (de) Verfahren zur Herstellung von künstlichen N-verbundenen Glycoconjugaten.
ATE109004T1 (de) Toleranzinduktion gegenüber einem fremdantigen.
DE3761405D1 (de) Verfahren zur herstellung eines roentgenbildverstaerkers und nach diesem verfahren hergestellter bildverstaerker.
FR2571146B1 (fr) Antigenes carcino-foetaux du pancreas humain et un procede de purification, antiserum contre ces antigenes et son procede de preparation et compositions diagnostiques les contenant
ATE39055T1 (de) Verfahren zur immunisierung von schweinen gegen die aujeszky-krankheit.
DE69232140D1 (de) Die herstellung von menschlichen, monoklonalen antikörpern, die gegen das oberflächenantigen von hepatitis b aktiv sind
Birnbaum et al. Local and systemic opsonic adherent, hemagglutinating and rosette forming activity in mice induced by respiratory immunization with sheep red blood cells

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time