ES2109929T3 - Procedimiento para preparar un glucano de levadura - Google Patents
Procedimiento para preparar un glucano de levaduraInfo
- Publication number
- ES2109929T3 ES2109929T3 ES91111143T ES91111143T ES2109929T3 ES 2109929 T3 ES2109929 T3 ES 2109929T3 ES 91111143 T ES91111143 T ES 91111143T ES 91111143 T ES91111143 T ES 91111143T ES 2109929 T3 ES2109929 T3 ES 2109929T3
- Authority
- ES
- Spain
- Prior art keywords
- glucan
- crustacea
- stimulate
- beta
- subphylum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229920001503 Glucan Polymers 0.000 title abstract 4
- 240000004808 Saccharomyces cerevisiae Species 0.000 title 1
- 241000238424 Crustacea Species 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 2
- 230000001900 immune effect Effects 0.000 abstract 2
- 229960005486 vaccine Drugs 0.000 abstract 2
- 241000251464 Coelacanthiformes Species 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 239000002131 composite material Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 210000005253 yeast cell Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
- A61K36/064—Saccharomycetales, e.g. baker's yeast
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Materials Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Polymers & Plastics (AREA)
- Genetics & Genomics (AREA)
- Medical Informatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Farming Of Fish And Shellfish (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Catching Or Destruction (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A UN PROCESO PARA ESTIMULAR EL SISTEMA INMUNOLOGICO DE LOS ANIMALES ACUATICOS DE LA CLASE OSTEICHTIES Y CRUSTACEA SUBPHYLUM QUE COMPRENDEN LA ADMINISTRACION DE UNA CANTIDAD EFECTIVA DE UNA GLUCANO DE PARED DE CELULA DE LEVADURA COMPUESTO DE UNIDADES DE GLUCOPIRANOSA ENLAZADAS PREDOMINANTEMENTE POR ENLACES BETA-1,3 GLUCOSIDICO, QUE TIENE AL MENOS UNA RAMA DE ESTE COMPUESTO DE UNIDADES DE GLUCOPIRANOSA ENLAZADAS POR ENLACES BETA-1,6 GLICOSIDICOS. ADEMAS LA INVENCION SE REFIERE A UN PROCESO PARA MEJORAR EL EFECTO DE LAS VACUNAS ADMINISTRANDO UNA CANTIDAD EFECTIVA DEL GLUCANO DE PARED DE CELULA DE LEVADURA JUNTO CON LOS ANTIGENO DE VACUNA. ESTA INVENCION TAMBIEN SE REFIERE A UN PROCESO PARA OBTENER UN GLUCANO PARTICULARMENTE EFECTIVO PARA ESTIMULAR EL SISTEMA INMUNOLOGICO DE LOS ANIMALES ACUATICOS DE LA CLASE OSTEICHTHYES Y CRUSTACEA SUBPHYLUM.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54957590A | 1990-07-06 | 1990-07-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2109929T3 true ES2109929T3 (es) | 1998-02-01 |
Family
ID=24193557
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES91111143T Expired - Lifetime ES2109929T3 (es) | 1990-07-06 | 1991-07-04 | Procedimiento para preparar un glucano de levadura |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5401727A (es) |
| EP (1) | EP0466037B1 (es) |
| JP (1) | JP2828799B2 (es) |
| AT (1) | ATE160787T1 (es) |
| AU (1) | AU628752B2 (es) |
| CA (1) | CA2040374C (es) |
| DE (1) | DE69128308T2 (es) |
| DK (1) | DK0466037T3 (es) |
| ES (1) | ES2109929T3 (es) |
| FI (1) | FI104537B (es) |
| GR (1) | GR3026130T3 (es) |
| NO (1) | NO305705B1 (es) |
Families Citing this family (71)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0665649B2 (ja) * | 1991-02-01 | 1994-08-24 | 台糖株式会社 | 甲殻類の生体防御能増強剤、感染症予防ワクチン及び飼料 |
| JP3522772B2 (ja) * | 1991-05-21 | 2004-04-26 | 台糖株式会社 | ワクチンの免疫効果増強剤 |
| EP0640348A1 (en) * | 1993-07-26 | 1995-03-01 | Akzo Nobel N.V. | Oil-based and water-based adjuvant mixture |
| DK0664671T3 (da) * | 1993-08-06 | 2003-01-06 | Biotec Pharmacon Asa | Dyrefoder omfattende gærglucan |
| JPH08113539A (ja) * | 1993-09-22 | 1996-05-07 | Nippon Paper Ind Co Ltd | 免疫増強剤及びその製造方法、並びにそれを用いた甲殻類及び魚類の養殖用飼料 |
| NO300692B1 (no) | 1994-04-29 | 1997-07-07 | Biotec Mackzymal As | Solubilisert forgrenet ß-1,3-glukan og anvendelse derav samt anvendelse av usolubilisert forgrenet ß-1,3-glukan |
| US5871751A (en) * | 1994-10-12 | 1999-02-16 | The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Renibacterium salmoninarum vaccine and method for its preparation |
| JP3744020B2 (ja) * | 1995-04-14 | 2006-02-08 | 日本製紙株式会社 | 免疫増強剤並びにそれを含有する甲殻類、魚類及び家畜用飼料 |
| SI0848592T1 (en) * | 1995-09-05 | 2001-02-28 | Baensch Tetra Werke | Antistress agents for aquatic animals |
| US5722346A (en) * | 1996-04-17 | 1998-03-03 | The Board Of Governors For Higher Education | Smolting feed |
| US5786343A (en) * | 1997-03-05 | 1998-07-28 | Immudyne, Inc. | Phagocytosis activator compositions and their use |
| WO1998047392A1 (en) * | 1997-04-18 | 1998-10-29 | Immudyne, Inc. | Gel delivery system for animal nutrition and health |
| US7030101B2 (en) | 1998-09-14 | 2006-04-18 | Nabi Biopharmaceuticals | Compositions of β-glucans and specific antibodies |
| ES2321892T3 (es) * | 1998-09-14 | 2009-06-12 | Nabi Biopharmaceuticals | Composiciones de beta-glucanos e inmunoglobulinas especificas. |
| US20020009463A1 (en) * | 2000-02-23 | 2002-01-24 | Jan Raa | Novel, non-antigenic, mucosal adjuvant formulation which enhances the effects of substances, including vaccine antigens, in contact with mucosal body surfaces |
| US20040127458A1 (en) * | 2000-11-06 | 2004-07-01 | Hunter Kenneth W. | Beta-glucan containing compositions, methods for manufacturing beta-glucans, and for manufacturing and using beta-glucans and conjugates thereof as vaccine adjuvants |
| US7816514B2 (en) | 2001-02-16 | 2010-10-19 | Cargill, Incorporated | Glucosamine and method of making glucosamine from microbial biomass |
| US7923437B2 (en) * | 2001-02-16 | 2011-04-12 | Cargill, Incorporated | Water soluble β-glucan, glucosamine, and N-acetylglucosamine compositions and methods for making the same |
| US8222232B2 (en) * | 2001-02-16 | 2012-07-17 | Cargill, Incorporated | Glucosamine and N-acetylglucosamine compositions and methods of making the same fungal biomass |
| US7323140B2 (en) * | 2001-03-28 | 2008-01-29 | Handylab, Inc. | Moving microdroplets in a microfluidic device |
| US6939864B1 (en) | 2001-07-09 | 2005-09-06 | Purdue Research Foundation | Animal feed compositions and methods of using the same |
| KR20050043751A (ko) * | 2001-11-06 | 2005-05-11 | 오리엔트 캔서 세라피 컴퍼니 리미티드 | 항암 조성물 |
| DE10222358A1 (de) * | 2002-05-21 | 2003-12-11 | Nutrinova Gmbh | ß-Glucanhaltiges Sorbinsäurepräparat als Futtermittelzusatz in der Nutztieraufzucht |
| US7018986B2 (en) * | 2002-09-20 | 2006-03-28 | Immudyne | Use of beta glucans for the treatment of osteoporosis and other diseases of bone resorption |
| GB0225502D0 (en) * | 2002-11-01 | 2002-12-11 | Zoolife Internat Ltd | Therapeutic and prophylactic preparations |
| GB0225503D0 (en) * | 2002-11-01 | 2002-12-11 | Zoolife Internat Ltd | Gel feed |
| JP2004210895A (ja) * | 2002-12-27 | 2004-07-29 | Immudyne Japan:Kk | 免疫機能を有する可能性β−グルカンの製造方法及び用途 |
| JP2007524354A (ja) * | 2003-01-29 | 2007-08-30 | イミュダイン インコーポレーティッド | 動物用の免疫増強剤 |
| GB2399752A (en) * | 2003-03-26 | 2004-09-29 | Micap Plc | Pharmaceutical composition comprising a fungal cell or cell fragment as adjuvant |
| ES2899590T3 (es) | 2004-01-23 | 2022-03-14 | Eden Research Plc | Métodos de eliminación de nematodos que comprenden la aplicación de un componente terpénico |
| NZ551644A (en) | 2004-05-20 | 2010-06-25 | Eden Research Plc | Compositions containing a hollow glucan particle or a cell wall particle encapsulating a terpene component, methods of making and using them |
| US7740861B2 (en) * | 2004-06-16 | 2010-06-22 | University Of Massachusetts | Drug delivery product and methods |
| AU2005284727A1 (en) * | 2004-09-17 | 2006-03-23 | University Of Massachusetts | Compositions and their uses for lysosomal enzyme deficiencies |
| US7306818B2 (en) * | 2005-01-03 | 2007-12-11 | Promd Biotech Co., Ltd. | Method for preventing and/or treating viral infection in aquatic animals |
| MX2007013725A (es) | 2005-05-05 | 2008-04-09 | Sensient Flavors Inc | Produccion de beta-glucanos y mananos. |
| AU2006306228A1 (en) * | 2005-10-24 | 2007-05-03 | University Of Massachusetts | Compositions and their uses for gene therapy of bone conditions |
| BRPI0619219B8 (pt) | 2005-11-30 | 2021-11-16 | Univ Cornell | Método para matar ácaros, método para tratar ou impedir a infestação por um ácaro em uma planta e uso de uma composição |
| WO2007063268A1 (en) | 2005-11-30 | 2007-06-07 | Eden Research Plc | Compositions and methods comprising terpenes or terpene mixtures selected from thymol, eugenol, geraniol, citral, and l-carvone |
| WO2008102151A1 (en) * | 2007-02-21 | 2008-08-28 | Biotec Pharmacon Asa | Medical uses of glucans |
| JP5153188B2 (ja) * | 2007-03-30 | 2013-02-27 | 小林製薬株式会社 | Th1/Th2バランス改善剤 |
| US20090061049A1 (en) * | 2007-08-28 | 2009-03-05 | Vadood Azarm | Feed compositions for aquatic animals and methods of making the same |
| US8389485B2 (en) * | 2007-10-29 | 2013-03-05 | University Of Massachusetts | Encapsulated nanoparticles for nucleic acid delivery |
| CN101878033A (zh) * | 2007-11-13 | 2010-11-03 | 生物科技医药公司 | 治疗或预防肠道炎症性疾病的方法 |
| WO2009067020A1 (en) | 2007-11-19 | 2009-05-28 | Calanus As | Bioactive copepod-compositions, processes for the production thereof, and use thereof to prevent or treat hosts infested by phylogenetically similar ectoparasites |
| US8815818B2 (en) | 2008-07-18 | 2014-08-26 | Rxi Pharmaceuticals Corporation | Phagocytic cell delivery of RNAI |
| US9493774B2 (en) | 2009-01-05 | 2016-11-15 | Rxi Pharmaceuticals Corporation | Inhibition of PCSK9 through RNAi |
| US20100267661A1 (en) * | 2009-03-17 | 2010-10-21 | Immudyne, Inc. | Beta glucans and methods of use thereof |
| US9095504B2 (en) | 2010-03-24 | 2015-08-04 | Rxi Pharmaceuticals Corporation | RNA interference in ocular indications |
| CA2794189C (en) | 2010-03-24 | 2022-01-11 | Rxi Pharmaceuticals Corporation | Rna interference in dermal and fibrotic indications |
| EP2603450B1 (en) | 2010-08-14 | 2016-11-02 | University of Massachusetts | Yeast cell wall particle for receptor-targeted nanoparticle delivery |
| EP2694030A2 (en) | 2011-03-04 | 2014-02-12 | Sana Pharma AS | Cosmetic formulations |
| GB201220940D0 (en) | 2012-11-21 | 2013-01-02 | Eden Research Plc | Method P |
| AP2016009288A0 (en) | 2013-11-21 | 2016-06-30 | Eden Research Plc | Pesticidal composition |
| WO2015085113A1 (en) | 2013-12-04 | 2015-06-11 | Rxi Pharmaceuticals Corporation | Methods for treatment of wound healing utilizing chemically modified oligonucleotides |
| CA2947270A1 (en) | 2014-04-28 | 2015-11-05 | Rxi Pharmaceuticals Corporation | Methods for treating cancer using nucleic acids targeting mdm2 or mycn |
| CA2947619A1 (en) | 2014-05-01 | 2015-11-05 | Rxi Pharmaceuticals Corporation | Methods for treatment of disorders in the front of the eye utilizing nucleic acid molecules |
| EP3188799B1 (en) | 2014-09-05 | 2022-07-06 | Phio Pharmaceuticals Corp. | Methods for treating aging and skin disorders using nucleic acids targeting tyr or mmp1 |
| US20170369872A1 (en) | 2014-12-18 | 2017-12-28 | Alnylam Pharmaceuticals, Inc. | Reversir tm compounds |
| GB201501793D0 (en) | 2015-02-03 | 2015-03-18 | Eden Research Plc | Encapsulation of high potency active agents |
| US10808247B2 (en) | 2015-07-06 | 2020-10-20 | Phio Pharmaceuticals Corp. | Methods for treating neurological disorders using a synergistic small molecule and nucleic acids therapeutic approach |
| US11001845B2 (en) | 2015-07-06 | 2021-05-11 | Phio Pharmaceuticals Corp. | Nucleic acid molecules targeting superoxide dismutase 1 (SOD1) |
| EP3138573A1 (en) * | 2015-07-09 | 2017-03-08 | Danstar Ferment AG | Compositions and methods for stimulating immune responses in human and/or animal |
| US11021707B2 (en) | 2015-10-19 | 2021-06-01 | Phio Pharmaceuticals Corp. | Reduced size self-delivering nucleic acid compounds targeting long non-coding RNA |
| CN106719136A (zh) * | 2016-11-30 | 2017-05-31 | 蚌埠市渔歌农业科技有限公司 | 一种防治鲶鱼病害的养殖方法 |
| JP7167059B2 (ja) | 2017-04-19 | 2022-11-08 | フィオ ファーマシューティカルズ コーポレーション | 核酸化合物の局所送達 |
| JP6530846B1 (ja) * | 2018-10-09 | 2019-06-12 | アサヒグループホールディングス株式会社 | 免疫賦活剤及び感染予防方法 |
| CA3160657A1 (en) | 2019-11-08 | 2021-05-14 | Phio Pharmaceuticals Corp. | Chemically modified oligonucleotides targeting bromodomain containing protein 4 (brd4) for immunotherapy |
| US20240226135A1 (en) * | 2021-05-21 | 2024-07-11 | Asahi Group Holdings, Ltd. | Immunostimulator and method of producing glucan composition |
| IL322261A (en) | 2023-02-09 | 2025-09-01 | Alnylam Pharmaceuticals Inc | Reverser molecules and methods of using them |
| WO2025078537A1 (en) | 2023-10-10 | 2025-04-17 | Ab Mauri (Uk) Ltd | Compositions comprising branched (1,3)(1,6)-beta-glucans for use in the treatment of cancer |
| WO2025078523A1 (en) | 2023-10-10 | 2025-04-17 | Ab Mauri (Uk) Ltd | Compositions comprising a combination of (1,3)(1,6)-beta-glucans and uses thereof in therapy |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3301848A (en) * | 1962-10-30 | 1967-01-31 | Pillsbury Co | Polysaccharides and methods for production thereof |
| GB2076418A (en) * | 1980-05-22 | 1981-12-02 | Sankyo Co | Hydrolyzed polysaccharide |
| SE456911B (sv) * | 1983-12-19 | 1988-11-14 | Olle Larm | Vattenloeslig, aminerad beta-1,3-bunden d-glukan och makrofagstimulerande komposition innehaallande densamma |
| JPS6120561A (ja) * | 1984-07-09 | 1986-01-29 | 住友ベークライト株式会社 | 医療用吸着剤 |
| US4810646A (en) * | 1984-11-28 | 1989-03-07 | Massachusetts Institute Of Technology | Glucan compositions and process for preparation thereof |
| US4739046A (en) * | 1985-08-19 | 1988-04-19 | Luzio Nicholas R Di | Soluble phosphorylated glucan |
| JPS6337801A (ja) * | 1986-07-31 | 1988-02-18 | Matsushita Electric Ind Co Ltd | タ−ンテ−ブル |
| CA1330303C (en) * | 1989-02-20 | 1994-06-21 | Libor Henry Nikl | Composition and process to enhance the efficacy of a fish vaccine |
-
1991
- 1991-04-12 CA CA002040374A patent/CA2040374C/en not_active Expired - Lifetime
- 1991-06-26 AU AU79338/91A patent/AU628752B2/en not_active Expired
- 1991-07-04 EP EP91111143A patent/EP0466037B1/en not_active Expired - Lifetime
- 1991-07-04 ES ES91111143T patent/ES2109929T3/es not_active Expired - Lifetime
- 1991-07-04 JP JP3164603A patent/JP2828799B2/ja not_active Expired - Lifetime
- 1991-07-04 DE DE69128308T patent/DE69128308T2/de not_active Expired - Lifetime
- 1991-07-04 DK DK91111143T patent/DK0466037T3/da active
- 1991-07-04 AT AT91111143T patent/ATE160787T1/de not_active IP Right Cessation
- 1991-07-05 FI FI913275A patent/FI104537B/fi not_active IP Right Cessation
- 1991-07-05 NO NO19912645A patent/NO305705B1/no not_active IP Right Cessation
-
1994
- 1994-02-02 US US08/190,435 patent/US5401727A/en not_active Expired - Lifetime
-
1998
- 1998-02-12 GR GR980400302T patent/GR3026130T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69128308T2 (de) | 1998-03-26 |
| FI104537B (fi) | 2000-02-29 |
| AU628752B2 (en) | 1992-09-17 |
| ATE160787T1 (de) | 1997-12-15 |
| JP2828799B2 (ja) | 1998-11-25 |
| CA2040374A1 (en) | 1992-01-07 |
| FI913275A0 (fi) | 1991-07-05 |
| NO912645D0 (no) | 1991-07-05 |
| AU7933891A (en) | 1992-01-23 |
| NO305705B1 (no) | 1999-07-12 |
| CA2040374C (en) | 1998-06-16 |
| NO912645L (no) | 1992-01-07 |
| EP0466037A2 (en) | 1992-01-15 |
| EP0466037A3 (en) | 1992-10-28 |
| GR3026130T3 (en) | 1998-05-29 |
| JPH04253703A (ja) | 1992-09-09 |
| US5401727A (en) | 1995-03-28 |
| DE69128308D1 (de) | 1998-01-15 |
| EP0466037B1 (en) | 1997-12-03 |
| FI913275L (fi) | 1992-01-07 |
| DK0466037T3 (da) | 1998-08-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK0466037T3 (da) | Fremgangsmåde til fremstilling af et gærglucan | |
| ES2155540T3 (es) | Adyuvante para vacunas que comprende un polisacarido sulfolipidico hidrofobo. | |
| ES2118109T3 (es) | Antigenos polisacaridos de streptococcus pneumoniae. | |
| ES2112270T3 (es) | Anticuerpo de recombinacion especifica del cd4. | |
| ES2191016T3 (es) | Anticuerpos monoclonales neutralizantes humanos para el virus respiratorio sincitial. | |
| PT714444E (pt) | Atenuacao de um epitopo imunodominante de um antigenio para utilizacao em vacinas e imunoterapias para plantas, animais e homens | |
| ES2099744T3 (es) | Sistema de localizacion. | |
| BR9912410A (pt) | Vacina para imunização de aves, e, processos para imunizar uma ave e para preparar uma vacina para imunizar uma ave | |
| ES2084827T3 (es) | Composiciones de vacuna mejoradas. | |
| AR002255A1 (es) | Una composicion que comprende una formulacion de antigeno microfluidizada y usos de dicha formulacion. | |
| ES2063033T3 (es) | Empleo de igf-ii en el tratamiento de la enfermedades de los huesos. | |
| ATE166530T1 (de) | Vorrichtung zur frühembryonalen in ovo injektion | |
| ES2134197T3 (es) | Vacunas contra el virus del herpes simplex vp16. | |
| AR004341A1 (es) | Vacunas contra tumores y procedimiento para su produccion. | |
| ATE255419T1 (de) | Für den vogelembryo geeignete multivalente impfstoffe | |
| ES2194836T3 (es) | Peptidos para su uso en vacunacion e induccion de anticuerpos neutralizantes contra el virus de la inmunodeficiencia humana. | |
| GB1183506A (en) | New vaccines for combating influenza and the preparation thereof | |
| MX9301014A (es) | Composiciones citoprotectora y metodos para preparar y usar las mismas. | |
| NL165217C (nl) | Werkwijze voor het bereiden van een vaccin voor het immuniseren van pluimvee tegen de ziekte van marek. | |
| AR023536A1 (es) | Vacunas | |
| ATE211923T1 (de) | Parenterale immunisierung gegen rotavirus | |
| ES8707296A1 (es) | Un metodo para producir anticuerpos monoclonales humanos | |
| ES544306A0 (es) | Procedimiento de producir antigenos relacionados con el enlace glicosidico derivados de cancer. | |
| ES2055610T3 (es) | Vacuna contra hrsv. | |
| ES2102836T3 (es) | El empleo de vacunas antihelminticas en el control de la enfermedad parasitaria asociada con la perdida de la inmunidad natural. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
Ref document number: 466037 Country of ref document: ES |