ATE16100T1 - Ester der 1-methyl-5-p-toluoylpyrrolyl-2essigs|ure mit antiinflammatorischen, mucolytischen und antitussiven eigenschaften, verfahren zu seiner herstellung und diese enthaltende pharmazeutische zusammensetzungen. - Google Patents
Ester der 1-methyl-5-p-toluoylpyrrolyl-2essigs|ure mit antiinflammatorischen, mucolytischen und antitussiven eigenschaften, verfahren zu seiner herstellung und diese enthaltende pharmazeutische zusammensetzungen.Info
- Publication number
- ATE16100T1 ATE16100T1 AT83830046T AT83830046T ATE16100T1 AT E16100 T1 ATE16100 T1 AT E16100T1 AT 83830046 T AT83830046 T AT 83830046T AT 83830046 T AT83830046 T AT 83830046T AT E16100 T1 ATE16100 T1 AT E16100T1
- Authority
- AT
- Austria
- Prior art keywords
- methyl
- mucolytic
- toluoylpyrrolyl
- inflammatory
- esters
- Prior art date
Links
- 230000000954 anitussive effect Effects 0.000 title abstract 2
- 230000003110 anti-inflammatory effect Effects 0.000 title abstract 2
- 230000000510 mucolytic effect Effects 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000002148 esters Chemical class 0.000 abstract 2
- LHGVFZTZFXWLCP-UHFFFAOYSA-N guaiacol Chemical compound COC1=CC=CC=C1O LHGVFZTZFXWLCP-UHFFFAOYSA-N 0.000 abstract 2
- UPSPUYADGBWSHF-UHFFFAOYSA-N tolmetin Chemical compound C1=CC(C)=CC=C1C(=O)C1=CC=C(CC(O)=O)N1C UPSPUYADGBWSHF-UHFFFAOYSA-N 0.000 abstract 2
- 230000003213 activating effect Effects 0.000 abstract 1
- 230000001754 anti-pyretic effect Effects 0.000 abstract 1
- 239000002221 antipyretic Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 229960001867 guaiacol Drugs 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrrole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT47938/82A IT1148117B (it) | 1982-03-05 | 1982-03-05 | Attivita'antiflogistica,analgesica,antipiretica,mucolitica e seda tiva della tosse dell'1 metil-5-p-tolilpirrol-2-acetato di 2'metossi-fenile |
| EP83830046A EP0088734B1 (de) | 1982-03-05 | 1983-03-02 | Ester der 1-Methyl-5-p-toluoylpyrrolyl-2-essigsäure mit antiinflammatorischen, mucolytischen und antitussiven Eigenschaften, Verfahren zu seiner Herstellung und diese enthaltende pharmazeutische Zusammensetzungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE16100T1 true ATE16100T1 (de) | 1985-11-15 |
Family
ID=11263480
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT83830046T ATE16100T1 (de) | 1982-03-05 | 1983-03-02 | Ester der 1-methyl-5-p-toluoylpyrrolyl-2essigs|ure mit antiinflammatorischen, mucolytischen und antitussiven eigenschaften, verfahren zu seiner herstellung und diese enthaltende pharmazeutische zusammensetzungen. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4521538A (de) |
| EP (1) | EP0088734B1 (de) |
| AT (1) | ATE16100T1 (de) |
| DE (1) | DE3361013D1 (de) |
| ES (1) | ES520319A0 (de) |
| IT (1) | IT1148117B (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1210673B (it) * | 1982-02-26 | 1989-09-20 | Medosan Ind Biochimi | Antinfiammatoria amidi pirrolacetiche ad attivita' |
| IT1197688B (it) * | 1983-07-29 | 1988-12-06 | Medosan Ind Biochimi | Attivita' antiflogistica,analgesica,antipiretica ed antiaggregante piastrinica di 1-metil-5-metilbenzoilpirrol-2-acetamido acetanilidi |
| US5648358A (en) * | 1996-03-05 | 1997-07-15 | Mitra; Sekhar | Compositions and methods for treating respiratory disorders |
| IT1297140B1 (it) * | 1997-12-24 | 1999-08-03 | Sigma Tau Ind Farmaceuti | Forma cristallina del guaiacil estere dell'acido l-metil-5-p-toluoil- pirrol-2-acetammidoacetico, procedimento per la sua preparazione e |
| JP4143218B2 (ja) | 1999-04-23 | 2008-09-03 | 株式会社日本触媒 | 薄膜式蒸発装置における重合防止方法および薄膜式蒸発装置 |
| CN1281573C (zh) * | 2001-11-20 | 2006-10-25 | 三菱化学株式会社 | 制备(甲基)丙烯酸化合物的方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3752826A (en) * | 1970-01-26 | 1973-08-14 | Mcneilab Inc | Aroyl substituted pyrroles |
| DE2861595D1 (en) * | 1978-07-10 | 1982-03-11 | Mcneilab Inc | Pharmaceutical composition comprising a 5-aroyl-1-c1-5 alkyl-pyrrole-2-acetic acid compound and acetaminophen or acetylsalicylic acid |
| US4284785A (en) * | 1979-12-19 | 1981-08-18 | American Cyanamid Company | Substituted phenyl esters of isoxazolecarboxylic acids |
| US4396626A (en) * | 1980-10-09 | 1983-08-02 | Beecham Group Limited | Cyclic compounds and their use |
| ES8200092A1 (es) * | 1980-11-11 | 1981-10-16 | Calzada & Co | Procedimiento para la sintesis de esteres de la n-(4'hidro- xifenil) acetamida con acidos 5-benzoil-1-metilpirrol-2-ace-tico |
-
1982
- 1982-03-05 IT IT47938/82A patent/IT1148117B/it active
-
1983
- 1983-03-02 EP EP83830046A patent/EP0088734B1/de not_active Expired
- 1983-03-02 AT AT83830046T patent/ATE16100T1/de not_active IP Right Cessation
- 1983-03-02 DE DE8383830046T patent/DE3361013D1/de not_active Expired
- 1983-03-04 ES ES520319A patent/ES520319A0/es active Granted
- 1983-03-04 US US06/472,255 patent/US4521538A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US4521538A (en) | 1985-06-04 |
| ES8404326A1 (es) | 1984-04-16 |
| DE3361013D1 (en) | 1985-11-21 |
| IT1148117B (it) | 1986-11-26 |
| IT8247938A0 (it) | 1982-03-05 |
| ES520319A0 (es) | 1984-04-16 |
| EP0088734B1 (de) | 1985-10-16 |
| EP0088734A1 (de) | 1983-09-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NL191332B (nl) | Farmaceutisch preparaat met de ethylester van (all-Z)-5,8,11,14,17-eicosapentaeenzuur. | |
| GB1432576A (en) | Substituted phenylacetic acids | |
| RU95112575A (ru) | Соль арилпропионовой кислоты, способ ее получения и фармацевтическая композиция | |
| IE45439L (en) | Penicillanic acid derivatives | |
| ATE18197T1 (de) | 1'-aethoxycarbonyloxyaethylester der valponsaeure, seine herstellung und diesen enthaltende formulierungen. | |
| IE39602B1 (en) | New alkoxyalkyl-1,4-dihydropyridines, their preparation, and their medicinal use | |
| JPS57183736A (en) | Novel derivative of phenylaliphatic carboxylic acid, manufacture, use as drug and composition containing same | |
| FR2355822A1 (fr) | Derives d'esters de l'acide indolacetique. utiles comme anti-inflammatoires et analgesiques | |
| DE3361013D1 (en) | A novel ester of the 1-methyl-5-p-toluoylpyrrolyl-2-acetic acid having antiinflammatory, mucolytic and antitussive properties, process for its preparation and pharmaceutical compositions containing them | |
| ES8502111A1 (es) | Un procedimiento de preparacion de diniflumato del ester morfolinoetilico del acido niflumico | |
| NO811340L (no) | Fremgangsmaate for fremstilling av cyklopropan-karboksylsyreester-derivater. | |
| PT87017A (pt) | Process for the preparation of pharmaceutical compositions acting on the heart and cardiovascular system containing a mixture of selenium-containing algae and higher unsaturated fatty acids | |
| GB1514389A (en) | Glycerides with antibacterial properties | |
| GB1498919A (en) | Furanose-o-pyridylcarboxylic acid esters | |
| EP0183149A3 (de) | Verfahren zur Herstellung von 4-Acyloxy-3-oxo-butter-säureestern | |
| JPS5711986A (en) | Okadaic acid, its salt, and its ester | |
| DK570282A (da) | Fremgangsmaade til fremstilling af et indolderivat | |
| ATE43964T1 (de) | Ester der (+)-6-methoxy-alpha-methyl-2naphthalenessigs|ure mit mucosekretolytischer, entzuendungshemmender, schmerzstillender, fieber erniedrigender wirkung, dessen herstellungsverfahren und dessen pharmazeutische zusammensetzungen. | |
| NO151618C (no) | Fremgangsmaate for fremstilling av cyklopropan-karboksylsyreester-derivater | |
| JPS52106857A (en) | Preparation of 1,3-disubstituted-2-azetidinones | |
| ES8207140A1 (es) | Un procedimiento para preparar esteres de pirrol . | |
| JPS5513242A (en) | N-isobutylamide derivative | |
| JPS5246066A (en) | Preparation of optically active 5-oxo-2-pyrrolipinyl acetic acid salts | |
| AU529728B2 (en) | Esters of arylpropionic acid derivatives, their preparation and pharmaceutical compositions containing them | |
| IT8222460A0 (it) | Esteri 2-metossi-fenilici di acidi 2', 4'-difluoro-4-idrossi-aperta parentesi quadra 1, 1'-bifenilchiusa parentesi quadra-3-carbossilici ad attivita'antiinfiammatoria e balsamica, procedimento per la loro preparazione e relative composizioni farmaceutiche. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |