ATE161730T1 - Antikörper zur behandlung von insulinabhängigen diabetes - Google Patents
Antikörper zur behandlung von insulinabhängigen diabetesInfo
- Publication number
- ATE161730T1 ATE161730T1 AT94909584T AT94909584T ATE161730T1 AT E161730 T1 ATE161730 T1 AT E161730T1 AT 94909584 T AT94909584 T AT 94909584T AT 94909584 T AT94909584 T AT 94909584T AT E161730 T1 ATE161730 T1 AT E161730T1
- Authority
- AT
- Austria
- Prior art keywords
- antibodies
- dependent diabetes
- treating insulin
- diabetes
- insulin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70542—CD106
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
- C07K16/2842—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta1-subunit-containing molecules, e.g. CD29, CD49
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2933093A | 1993-02-09 | 1993-02-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE161730T1 true ATE161730T1 (de) | 1998-01-15 |
Family
ID=21848497
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94909584T ATE161730T1 (de) | 1993-02-09 | 1994-02-09 | Antikörper zur behandlung von insulinabhängigen diabetes |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US5888507A (es) |
| EP (1) | EP0682529B2 (es) |
| JP (1) | JP3593343B2 (es) |
| AT (1) | ATE161730T1 (es) |
| AU (1) | AU687790B2 (es) |
| CA (1) | CA2155303C (es) |
| DE (1) | DE69407758T3 (es) |
| DK (1) | DK0682529T4 (es) |
| ES (1) | ES2114183T5 (es) |
| GR (1) | GR3026531T3 (es) |
| NZ (1) | NZ262615A (es) |
| WO (1) | WO1994017828A2 (es) |
Families Citing this family (72)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE40811E1 (en) | 1992-11-13 | 2009-06-30 | Board Of Regents Of The University Of Washington | Peripheralization of hematopoietic stem cells |
| SG44845A1 (en) * | 1993-01-12 | 1997-12-19 | Biogen Inc | Recombitant anti-vla4 antibody molecules |
| WO1994017828A2 (en) * | 1993-02-09 | 1994-08-18 | Biogen, Inc. | Treatment for insulin dependent diabetes |
| US5677291A (en) * | 1993-12-10 | 1997-10-14 | Hoechst Marion Roussel, Inc. | Method of lowering serum cholesterol levels with 2,6-di-alkyl-4-silyl-phenols |
| US5750336A (en) * | 1994-02-10 | 1998-05-12 | The Salk Institute For Biological Studies | Assays for the identification of compounds which inhibit activation of cAMP and mitogen responsive genes |
| US7803904B2 (en) | 1995-09-01 | 2010-09-28 | Millennium Pharmaceuticals, Inc. | Mucosal vascular addressing and uses thereof |
| US6551593B1 (en) | 1995-02-10 | 2003-04-22 | Millennium Pharmaceuticals, Inc. | Treatment of Inflammatory bowel disease by inhibiting binding and/or signalling through α 4 β 7 and its ligands and madcam |
| US5608095A (en) * | 1996-04-30 | 1997-03-04 | Hoechst Marion Roussel, Inc. | Alkyl-4-silyl-phenols and esters thereof as antiatherosclerotic agents |
| US5795876A (en) * | 1996-04-30 | 1998-08-18 | Hoechst Marion Rousssel, Inc. | Method of inhibiting vascular cell adhesion molecule-1 and treating chronic inflammatory diseases with 2, 6-di-alkyl-4-silyl-phenols |
| US7147851B1 (en) * | 1996-08-15 | 2006-12-12 | Millennium Pharmaceuticals, Inc. | Humanized immunoglobulin reactive with α4β7 integrin |
| US6114572A (en) * | 1996-11-20 | 2000-09-05 | Hoechst Marion Roussel, Inc. | Substituted phenols and thiophenols useful as antioxidant agents |
| CN1257545A (zh) * | 1997-04-18 | 2000-06-21 | 拜奥根有限公司 | Ⅱ型TGF-β受体/免疫球蛋白恒定区融合蛋白 |
| US6121463A (en) * | 1997-06-24 | 2000-09-19 | Hoechst Marion Roussel, Inc. | Alkyl-4-silylheterocyclic phenols and thiophenols useful as antioxidant agents |
| US6133467A (en) * | 1997-06-25 | 2000-10-17 | Hoechst Marion Roussel, Inc. | 2,6-di-t-butyl-4-[(dimethyl-4-methoxyphenylsilyl)-methyl-oxy]phenol and 2,6-di-t-butyl-4-[(dimethyl-2-methoxy-phenylsilyl)methyloxy]phenol |
| DE19741235A1 (de) | 1997-09-18 | 1999-03-25 | Hoechst Marion Roussel De Gmbh | Neue Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
| DE19741873A1 (de) * | 1997-09-23 | 1999-03-25 | Hoechst Marion Roussel De Gmbh | Neue 5-Ring-Heterocyclen, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
| DE19751251A1 (de) | 1997-11-19 | 1999-05-20 | Hoechst Marion Roussel De Gmbh | Substituierte Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmezeutische Präparate |
| DE19821483A1 (de) | 1998-05-14 | 1999-11-18 | Hoechst Marion Roussel De Gmbh | Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
| US7618630B2 (en) | 1998-09-14 | 2009-11-17 | Board Of Regents, The University Of Texas System | Methods of treating multiple myeloma and myeloma-induced bone resorption using integrin antagonists |
| ES2319831T3 (es) | 1998-09-14 | 2009-05-12 | Board Of Regents, The University Of Texas System | Metodos de tratamiento de mieloma multiple y resorcion osea inducida por mieloma usando antagonistas de la union receptor/integrina. |
| US6110109A (en) * | 1999-03-26 | 2000-08-29 | Biosignia, Inc. | System and method for predicting disease onset |
| ES2243259T3 (es) * | 1999-04-22 | 2005-12-01 | Biogen Idec Ma Inc. | Metodo para tratar la fibrosis utilizando un antagonista de la subunidad alfa 4 de la integrina. |
| DE19922462A1 (de) | 1999-05-17 | 2000-11-23 | Aventis Pharma Gmbh | Spiro-imidazolidinderivate, ihre Herstellung ihre Verwendung und sie enthaltende pharmazeutische Präparate |
| EP1181054A1 (en) | 1999-06-01 | 2002-02-27 | Biogen, Inc. | A blocking monoclonal antibody to vla-1 and its use for the treatment of inflammatory disorders |
| EP1214091B1 (en) * | 1999-09-14 | 2006-05-10 | Biogen Idec MA Inc. | Therapies for chronic renal failure using one or more integrin antagonists |
| US20010046489A1 (en) | 1999-12-06 | 2001-11-29 | Habener Joel E. | Stem cells of the islets of langerhans and their use in treating diabetes mellitus |
| AU783110B2 (en) * | 1999-12-16 | 2005-09-22 | Biogen Ma Inc. | Methods of treating central nervous system ischemic or hemorrhagic injury using anti alpha4 integrin antagonists |
| US20060115473A1 (en) * | 2000-12-14 | 2006-06-01 | Biogen Idec Ma Inc., A Massachusetts Corporation | Methods of treating central nervous system ischemic or hemorrhagic injury using anti alpha4 integrin antagonists |
| JP3459609B2 (ja) * | 2000-03-17 | 2003-10-20 | 三洋電機株式会社 | ライトキャッシュ回路、ライトキャッシュ回路を備えた記録装置、およびライトキャッシュ方法 |
| US20010046496A1 (en) * | 2000-04-14 | 2001-11-29 | Brettman Lee R. | Method of administering an antibody |
| DE10111877A1 (de) | 2001-03-10 | 2002-09-12 | Aventis Pharma Gmbh | Neue Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
| EP1423431B1 (en) | 2001-04-13 | 2010-06-16 | Biogen Idec MA Inc. | Antibodies to vla-1 |
| DE10137595A1 (de) | 2001-08-01 | 2003-02-13 | Aventis Pharma Gmbh | Neue Imidazolidinderivate, ihre Herstellung und ihre Verwendung |
| FR2849598B1 (fr) * | 2003-01-07 | 2006-09-22 | Merck Sante Sas | Utilisation d'inhibiteurs de la kynurenine-3-hydroxylase pour le traitement du diabete, par augmentation du nombre de cellules des ilots de langerhans |
| JP2007521249A (ja) | 2003-01-24 | 2007-08-02 | エラン ファーマシューティカルズ,インコーポレイテッド | 脱髄疾患および麻痺のための組成物ならびに再有髄化剤を投与することによるそれらの治療 |
| US7419666B1 (en) | 2004-02-23 | 2008-09-02 | Massachusetts Eye And Ear Infirmary | Treatment of ocular disorders |
| CA2478458A1 (en) * | 2004-08-20 | 2006-02-20 | Michael Panzara | Treatment of pediatric multiple sclerosis |
| CA2587597A1 (en) | 2004-11-19 | 2006-05-26 | Biogen Idec Ma Inc. | Treatment for multiple sclerosis |
| NZ581497A (en) * | 2004-12-03 | 2012-07-27 | Biogen Idec Inc | Delaying or preventing onset of multiple sclerosis by vla-4 ginding antibody |
| US8124350B2 (en) | 2005-04-04 | 2012-02-28 | Biogen Idec Ma Inc. | Methods and products for evaluating an immune response to a therapeutic protein |
| EP1948691A1 (en) * | 2005-11-17 | 2008-07-30 | Millennium Pharmaceuticals, Inc. | HUMANIZED IMMUNOGLOBULIN REACTIVE WITH a4ß7INTEGRIN |
| CA2652815C (en) | 2006-05-25 | 2015-12-15 | Biogen Idec Ma Inc. | Methods of treating stroke |
| CA2690382A1 (en) | 2007-06-14 | 2008-12-24 | Biogen Idec Ma Inc. | Antibody formulations |
| ES2824261T3 (es) | 2007-09-14 | 2021-05-11 | Biogen Ma Inc | Composiciones y procedimientos para el tratamiento de la leucoencefalopatía multifocal progresiva (LMP) |
| EP2315779A2 (en) | 2008-07-09 | 2011-05-04 | Biogen Idec MA Inc. | Compositions comprising antibodies to lingo or fragments thereof |
| MX2011010971A (es) * | 2009-04-17 | 2012-01-19 | Biogen Idec Inc | Composiciones y metodos para tratar leucemia mielogena aguda. |
| EP2467159A1 (en) | 2009-08-20 | 2012-06-27 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Vla-4 as a biomarker for prognosis and target for therapy in duchenne muscular dystrophy |
| EP2485762B1 (en) | 2009-10-11 | 2017-12-13 | Biogen MA Inc. | Anti-vla-4 related assays |
| ES2912934T3 (es) | 2010-04-16 | 2022-05-30 | Biogen Ma Inc | Anticuerpos anti VLA-4 |
| EP3722808B1 (en) | 2010-10-25 | 2024-09-11 | Biogen MA Inc. | Methods for determining differences in alpha-4 integrin activity by correlating differences in svcam and/or smadcam levels |
| UA116189C2 (uk) | 2011-05-02 | 2018-02-26 | Мілленніум Фармасьютікалз, Інк. | КОМПОЗИЦІЯ АНТИ-α4β7 АНТИТІЛА |
| UY34054A (es) | 2011-05-02 | 2012-11-30 | Millennium Pharm Inc | FORMULACIÓN PARA ANTICUERPO ANTI-a(alfa)4B(Beta)7 |
| WO2013123114A2 (en) | 2012-02-16 | 2013-08-22 | Santarus, Inc. | Antibody formulations |
| EP3575311A1 (en) | 2012-03-20 | 2019-12-04 | Biogen MA Inc. | Jcv neutralizing antibodies |
| EP2845134A1 (en) | 2012-04-20 | 2015-03-11 | Biogen Idec MA Inc. | Cognitive composite parameters and uses thereof for evaluating multiple sclerosis |
| US9796780B2 (en) | 2012-05-14 | 2017-10-24 | Biogen Ma Inc. | LINGO-2 antagonists for treatment of conditions involving motor neurons |
| US8735359B2 (en) * | 2012-05-24 | 2014-05-27 | Orban Biotech Llc | Combinations of modalities for the treatment of diabetes |
| EP2883177A1 (en) | 2012-08-13 | 2015-06-17 | Biogen Idec MA Inc. | Disease progression parameters and uses thereof for evaluating multiple sclerosis |
| MX2015004436A (es) | 2012-10-09 | 2015-06-24 | Biogen Idec Inc | Tratamientos conjuntos y usos para tratar trastornos desmielinizantes. |
| WO2015063604A2 (en) | 2013-11-01 | 2015-05-07 | Imberti Luisa | BIOMARKERS PREDICTIVE OF THERAPEUTIC RESPONSIVENESS TO IFNβ AND USES THEREOF |
| WO2016112270A1 (en) | 2015-01-08 | 2016-07-14 | Biogen Ma Inc. | Lingo-1 antagonists and uses for treatment of demyelinating disorders |
| US10118904B2 (en) | 2015-06-05 | 2018-11-06 | Vertex Pharmaceuticals Incorporated | Triazoles for the treatment of Demyelinating Diseases |
| WO2018013714A1 (en) | 2016-07-13 | 2018-01-18 | Biogen Ma Inc. | Dosage regimens of lingo-1 antagonists and uses for treatment of demyelinating disorders |
| WO2018045162A1 (en) | 2016-09-01 | 2018-03-08 | Biogen Ma Inc. | Biomarkers predictive of primary progressive multiple sclerosis and uses thereof |
| WO2018106646A1 (en) | 2016-12-06 | 2018-06-14 | Vertex Pharmaceuticals Incorporated | Aminotriazoles for the treatment of demyelinating diseases |
| WO2018106641A1 (en) | 2016-12-06 | 2018-06-14 | Vertex Pharmaceuticals Incorporated | Pyrazoles for the treatment of demyelinating diseases |
| WO2018106643A1 (en) | 2016-12-06 | 2018-06-14 | Vertex Pharmaceuticals Incorporated | Heterocyclic azoles for the treatment of demyelinating diseases |
| WO2018140510A1 (en) | 2017-01-25 | 2018-08-02 | Biogen Ma Inc. | Compositions and methods for treatment of stroke and other cns disorders |
| CN112867394B9 (zh) | 2018-06-04 | 2024-12-06 | 马萨诸塞州渤健公司 | 具有降低的效应功能的抗vla-4抗体 |
| BR112021017644A2 (pt) | 2019-03-11 | 2021-11-16 | Biogen Ma Inc | Composições farmacêuticas contendo anticorpos anti-lingo-1 |
| US20240301512A1 (en) | 2021-01-29 | 2024-09-12 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods of assessing the risk of developing progressive multifocal leukoencephalopathy in patients treated with vla-4 antagonists |
| US20230382993A1 (en) * | 2022-05-24 | 2023-11-30 | Provention Bio, Inc. | Methods and compositions for preventing or delaying type 1 diabetes |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ215865A (en) * | 1985-04-22 | 1988-10-28 | Commw Serum Lab Commission | Method of determining the active site of a receptor-binding analogue |
| US4879313A (en) * | 1988-07-20 | 1989-11-07 | Mosanto Company | Novel platelet-aggregation inhibitors |
| US5053393A (en) * | 1988-07-20 | 1991-10-01 | Monsanto Company | Novel platelet-aggregation inhibitor |
| CA2002860A1 (en) * | 1988-11-14 | 1990-05-14 | Michael A. Gimbrone | Antibodies specific for elam-1 and the use thereof |
| US5225538A (en) * | 1989-02-23 | 1993-07-06 | Genentech, Inc. | Lymphocyte homing receptor/immunoglobulin fusion proteins |
| US5272263A (en) * | 1989-04-28 | 1993-12-21 | Biogen, Inc. | DNA sequences encoding vascular cell adhesion molecules (VCAMS) |
| US5217870A (en) * | 1989-04-28 | 1993-06-08 | Biogen, Inc. | Monoclonal antibodies against CDX |
| US5061693A (en) * | 1989-07-28 | 1991-10-29 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| IL113261A (en) † | 1989-09-01 | 1996-10-16 | Hutchinson Fred Cancer Res | Inhibition by peptides of lymphocyte adherence to vascular endothelium utilizing an extracellular matrix receptor-ligand interaction and pharmaceutical compositions containing said peptides |
| US4952562A (en) * | 1989-09-29 | 1990-08-28 | Rorer Pharmaceutical Corporation | Anti-thrombotic peptides and pseudopeptides |
| US5053392A (en) * | 1989-12-01 | 1991-10-01 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Novel arginine, glycine, aspartic acid derivatives as platelet-aggregation inhibitors |
| US5260277A (en) * | 1990-09-10 | 1993-11-09 | Tanabe Seiyaku Co., Ltd. | Guanidinyl and related cell adhesion modulation compounds |
| WO1993008823A1 (en) * | 1991-11-06 | 1993-05-13 | Tanabe Seiyaku Co., Ltd. | Guanidinyl and related cell adhesion modulation compounds |
| CA2127462C (en) * | 1992-01-13 | 1999-03-23 | Roy R. Lobb | Treatment for asthma |
| JPH07506566A (ja) * | 1992-02-12 | 1995-07-20 | バイオゲン インコーポレイテッド | 炎症性胃腸病の処置 |
| USRE40811E1 (en) * | 1992-11-13 | 2009-06-30 | Board Of Regents Of The University Of Washington | Peripheralization of hematopoietic stem cells |
| US5591719A (en) * | 1992-12-10 | 1997-01-07 | Regents Of The University Of Minnesota | Method for treating acute and chronic inflammatory disorders using polypeptides with fibronectin activity |
| SG44845A1 (en) * | 1993-01-12 | 1997-12-19 | Biogen Inc | Recombitant anti-vla4 antibody molecules |
| WO1994017828A2 (en) * | 1993-02-09 | 1994-08-18 | Biogen, Inc. | Treatment for insulin dependent diabetes |
| DE69535133T2 (de) * | 1994-01-25 | 2008-08-21 | Elan Pharmaceuticals, Inc., San Francisco | Humanisierte antikörper gegen das leukozytenadhäsionsmolekül vla-4 |
-
1994
- 1994-02-09 WO PCT/US1994/001456 patent/WO1994017828A2/en not_active Ceased
- 1994-02-09 JP JP51833394A patent/JP3593343B2/ja not_active Expired - Fee Related
- 1994-02-09 ES ES94909584T patent/ES2114183T5/es not_active Expired - Lifetime
- 1994-02-09 AT AT94909584T patent/ATE161730T1/de active
- 1994-02-09 CA CA2155303A patent/CA2155303C/en not_active Expired - Fee Related
- 1994-02-09 AU AU62379/94A patent/AU687790B2/en not_active Ceased
- 1994-02-09 DE DE69407758T patent/DE69407758T3/de not_active Expired - Lifetime
- 1994-02-09 DK DK94909584T patent/DK0682529T4/da active
- 1994-02-09 EP EP94909584A patent/EP0682529B2/en not_active Expired - Lifetime
- 1994-02-09 NZ NZ262615A patent/NZ262615A/en not_active IP Right Cessation
-
1995
- 1995-05-22 US US08/447,118 patent/US5888507A/en not_active Expired - Lifetime
-
1998
- 1998-04-03 GR GR980400715T patent/GR3026531T3/el unknown
-
2005
- 2005-04-11 US US11/103,362 patent/US20050208053A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE69407758T2 (de) | 1998-08-27 |
| WO1994017828A3 (en) | 1994-10-13 |
| JPH08508719A (ja) | 1996-09-17 |
| EP0682529A1 (en) | 1995-11-22 |
| CA2155303A1 (en) | 1994-08-18 |
| EP0682529B1 (en) | 1998-01-07 |
| CA2155303C (en) | 2010-04-20 |
| DK0682529T3 (da) | 1998-09-07 |
| DE69407758T3 (de) | 2007-05-24 |
| WO1994017828A2 (en) | 1994-08-18 |
| ES2114183T5 (es) | 2006-06-16 |
| DK0682529T4 (da) | 2006-05-15 |
| EP0682529B2 (en) | 2005-12-28 |
| GR3026531T3 (en) | 1998-07-31 |
| HK1008731A1 (en) | 1999-05-14 |
| NZ262615A (en) | 1996-02-27 |
| AU6237994A (en) | 1994-08-29 |
| DE69407758D1 (de) | 1998-02-12 |
| US20050208053A1 (en) | 2005-09-22 |
| AU687790B2 (en) | 1998-03-05 |
| JP3593343B2 (ja) | 2004-11-24 |
| ES2114183T3 (es) | 1998-05-16 |
| US5888507A (en) | 1999-03-30 |
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