ATE162709T1 - Oberflächenaktivmittelfreie aerosolformulierungen enthaltend beclomethason dipropionat - Google Patents

Oberflächenaktivmittelfreie aerosolformulierungen enthaltend beclomethason dipropionat

Info

Publication number: ATE162709T1
Authority: AT; Austria
Prior art keywords: dipropionate; beclomethason; surfactant; aerosol formulations; formulations containing
Prior art date: 1992-07-31

Application number

AT93917708T

Other languages

English (en)

Inventor

Anthony James Taylor

Philip John Neale

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-07-31

Filing date

1993-07-30

Publication date

1998-02-15

1992-07-31 Priority claimed from GB929216381A external-priority patent/GB9216381D0/en

1992-07-31 Priority claimed from GB929216382A external-priority patent/GB9216382D0/en

1993-07-30 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

1998-02-15 Application granted granted Critical

1998-02-15 Publication of ATE162709T1 publication Critical patent/ATE162709T1/de

Links

239000000443 aerosol Substances 0.000 title abstract 3
239000000203 mixture Substances 0.000 title abstract 3
238000009472 formulation Methods 0.000 abstract 2
YFMFNYKEUDLDTL-UHFFFAOYSA-N 1,1,1,2,3,3,3-heptafluoropropane Chemical compound FC(F)(F)C(F)C(F)(F)F YFMFNYKEUDLDTL-UHFFFAOYSA-N 0.000 abstract 1
KUVIULQEHSCUHY-XYWKZLDCSA-N Beclometasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(Cl)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)COC(=O)CC)(OC(=O)CC)[C@@]1(C)C[C@@H]2O KUVIULQEHSCUHY-XYWKZLDCSA-N 0.000 abstract 1
229950000210 beclometasone dipropionate Drugs 0.000 abstract 1
229940092705 beclomethasone Drugs 0.000 abstract 1
-1 beclomethasone ester Chemical class 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
239000003380 propellant Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Otolaryngology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT93917708T 1992-07-31 1993-07-30 Oberflächenaktivmittelfreie aerosolformulierungen enthaltend beclomethason dipropionat ATE162709T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB929216381A GB9216381D0 (en)	1992-07-31	1992-07-31	Medicaments
GB929216382A GB9216382D0 (en)	1992-07-31	1992-07-31	Medicaments

Publications (1)

Publication Number	Publication Date
ATE162709T1 true ATE162709T1 (de)	1998-02-15

Family

ID=26301356

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT97101101T ATE248582T1 (de)	1992-07-31	1993-07-30	Oberflächenaktivmittelfreie aerosolformulierungen enthaltend beclomethasondipropionat
AT93917708T ATE162709T1 (de)	1992-07-31	1993-07-30	Oberflächenaktivmittelfreie aerosolformulierungen enthaltend beclomethason dipropionat

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AT97101101T ATE248582T1 (de)	1992-07-31	1993-07-30	Oberflächenaktivmittelfreie aerosolformulierungen enthaltend beclomethasondipropionat

Country Status (11)

Country	Link
EP (2)	EP0658101B1 (de)
JP (1)	JPH07509475A (de)
CN (1)	CN1052401C (de)
AT (2)	ATE248582T1 (de)
AU (1)	AU670616B2 (de)
DE (2)	DE69316760T2 (de)
DK (1)	DK0658101T3 (de)
ES (2)	ES2206619T3 (de)
GR (1)	GR3026185T3 (de)
MX (1)	MX9304585A (de)
WO (1)	WO1994003153A1 (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7105152B1 (en)	1991-12-18	2006-09-12	3M Innovative Properties Company	Suspension aerosol formulations
US7101534B1 (en)	1991-12-18	2006-09-05	3M Innovative Properties Company	Suspension aerosol formulations
WO1994021386A2 (en) *	1993-03-25	1994-09-29	Research Corporation Technologies, Inc.	Polymers useful in forming self-assembled bonded anisotropic ultrathin layers and their use
US5508023A (en) *	1994-04-11	1996-04-16	The Center For Innovative Technology	Pharmaceutically acceptable agents for solubilizing, wetting, emulsifying, or lubricating in metered dose inhaler formulations which use HFC-227 propellant
GB9425160D0 (en) *	1994-12-10	1995-02-08	Glaxo Group Ltd	Medicaments
US5747001A (en) *	1995-02-24	1998-05-05	Nanosystems, L.L.C.	Aerosols containing beclomethazone nanoparticle dispersions
TR199701170T1 (xx) *	1995-04-14	1998-02-21	Glaxo Wellcome Inc.	Beklometazon dipropionat i�in �l��lm�� doz inhaleri.
HU219900B (hu) *	1995-04-14	2001-09-28	Glaxo Wellcome Inc.	Mért dózist adagoló inhalálóberendezés
GB9616237D0 (en)	1996-08-01	1996-09-11	Norton Healthcare Ltd	Aerosol formulations
US6068832A (en) *	1996-08-29	2000-05-30	Schering Corporation	Chlorofluorocarbon-free mometasone furoate aerosol formulations
US6054487A (en) *	1997-03-18	2000-04-25	Basf Aktiengesellschaft	Methods and compositions for modulating responsiveness to corticosteroids
SK122199A3 (en) *	1997-03-18	2000-12-11	Basf Ag	Methods and compositions for modulating responsiveness to corticosteroids
US6433040B1 (en)	1997-09-29	2002-08-13	Inhale Therapeutic Systems, Inc.	Stabilized bioactive preparations and methods of use
US6565885B1 (en)	1997-09-29	2003-05-20	Inhale Therapeutic Systems, Inc.	Methods of spray drying pharmaceutical compositions
US6309623B1 (en)	1997-09-29	2001-10-30	Inhale Therapeutic Systems, Inc.	Stabilized preparations for use in metered dose inhalers
US6946117B1 (en)	1997-09-29	2005-09-20	Nektar Therapeutics	Stabilized preparations for use in nebulizers
US20060165606A1 (en)	1997-09-29	2006-07-27	Nektar Therapeutics	Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6086376A (en) *	1998-01-30	2000-07-11	Rtp Pharma Inc.	Dry aerosol suspension of phospholipid-stabilized drug microparticles in a hydrofluoroalkane propellant
US20060171899A1 (en) *	1998-12-10	2006-08-03	Akwete Adjei	Water-stabilized aerosol formulation system and method of making
DK1169019T3 (da)	1999-04-14	2003-06-02	Glaxo Group Ltd	Farmaceutisk aerosolformulering
US6540982B1 (en) *	2000-01-25	2003-04-01	Aeropharm Technology Incorporated	Medical aerosol formulation
PT1280520E (pt)	2000-05-10	2014-12-16	Novartis Ag	Pós à base de fosfolípidos para administração de fármacos
US8404217B2 (en)	2000-05-10	2013-03-26	Novartis Ag	Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US7871598B1 (en)	2000-05-10	2011-01-18	Novartis Ag	Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
PT1372608E (pt) *	2001-03-30	2008-01-04	Jagotec Ag	Formulações de aerossol médicas
US6455028B1 (en)	2001-04-23	2002-09-24	Pharmascience	Ipratropium formulation for pulmonary inhalation
GB0208742D0 (en)	2002-04-17	2002-05-29	Bradford Particle Design Ltd	Particulate materials
PT1458360E (pt)	2001-12-19	2011-07-13	Novartis Ag	Derivados de indole como agonistas do recetor s1p1
US7582284B2 (en)	2002-04-17	2009-09-01	Nektar Therapeutics	Particulate materials
CN100369608C (zh) *	2006-03-15	2008-02-20	修涞贵	一种治疗过敏性鼻炎的混悬液型喷雾剂及制备方法
EP2074421B1 (de) *	2006-10-12	2014-12-17	Koninklijke Philips N.V.	Schneller biosensor mit reagenzschicht
WO2008097664A1 (en)	2007-02-11	2008-08-14	Map Pharmaceuticals, Inc.	Method of therapeutic administration of dhe to enable rapid relief of migraine while minimizing side effect profile

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1429184A (en)	1972-04-20	1976-03-24	Allen & Hanburys Ltd	Physically anti-inflammatory steroids for use in aerosols
IT1121513B (it)	1979-05-28	1986-04-02	Chiesi Farma Spa	Processo per la conversione di umo steroide antiinfiammatorio in una forma suscettibile di essere somministarta come aerosol
ATE3774T1 (de)	1980-05-02	1983-06-15	Schering Corporation	Beclomethason-ester-solvate, verfahren zu ihrer herstellung und herstellung einer formulierung.
FI63672C (fi) *	1980-05-19	1983-08-10	Orion Yhtymae Oy	Foerfarande foer framstaellning av en blandning av beklometasondipropionat och triklorfluormetan eller diklordifluormetan
DK336485A (da)	1984-07-25	1986-01-26	Hovione Int Ltd	Fremgangsmaade til fremstilling af et diisopropylaetersolvat af beclomethason-17,21-dipropionat
GB8432063D0 (en)	1984-12-19	1985-01-30	Riker Laboratories Inc	Physically modified steroids
GB8828477D0 (en) *	1988-12-06	1989-01-05	Riker Laboratories Inc	Medical aerosol formulations
DE69131867T2 (de)	1990-03-23	2000-05-18	Minnesota Mining And Mfg. Co., Saint Paul	Anwendung von löslichen fluorhaltigen Tensiden zur Herstellung von Aerosol-Präparaten mit dosierter Abgabe
WO1992000061A1 (en) *	1990-06-29	1992-01-09	Fisons Plc	Pressurised aerosol compositions
ATE114112T1 (de)	1990-10-18	1994-12-15	Minnesota Mining & Mfg	Aerosolzubereitung, die beclometason 17,21- dipropionat enthält.
CA2111002C (en) *	1991-06-10	2000-08-22	Julianne Fassberg	Non-chlorofluorocarbon aerosol formulations
ATE339952T1 (de) *	1991-06-10	2006-10-15	Schering Corp	Fluorchlorkohlenwasserstofffreie aerosolformulierungen

1993
- 1993-07-29 MX MX9304585A patent/MX9304585A/es not_active IP Right Cessation
- 1993-07-30 EP EP93917708A patent/EP0658101B1/de not_active Expired - Lifetime
- 1993-07-30 AU AU47050/93A patent/AU670616B2/en not_active Ceased
- 1993-07-30 DK DK93917708T patent/DK0658101T3/da active
- 1993-07-30 EP EP97101101A patent/EP0775484B1/de not_active Expired - Lifetime
- 1993-07-30 DE DE69316760T patent/DE69316760T2/de not_active Expired - Fee Related
- 1993-07-30 ES ES97101101T patent/ES2206619T3/es not_active Expired - Lifetime
- 1993-07-30 WO PCT/EP1993/002040 patent/WO1994003153A1/en not_active Ceased
- 1993-07-30 ES ES93917708T patent/ES2112988T3/es not_active Expired - Lifetime
- 1993-07-30 CN CN93116824A patent/CN1052401C/zh not_active Expired - Fee Related
- 1993-07-30 JP JP6504996A patent/JPH07509475A/ja active Pending
- 1993-07-30 AT AT97101101T patent/ATE248582T1/de not_active IP Right Cessation
- 1993-07-30 AT AT93917708T patent/ATE162709T1/de not_active IP Right Cessation
- 1993-07-30 DE DE69333187T patent/DE69333187T2/de not_active Expired - Fee Related
1998
- 1998-02-20 GR GR980400363T patent/GR3026185T3/el unknown

Also Published As

Publication number	Publication date
AU670616B2 (en)	1996-07-25
JPH07509475A (ja)	1995-10-19
CN1088436A (zh)	1994-06-29
ATE248582T1 (de)	2003-09-15
EP0775484B1 (de)	2003-09-03
WO1994003153A1 (en)	1994-02-17
EP0658101A1 (de)	1995-06-21
AU4705093A (en)	1994-03-03
GR3026185T3 (en)	1998-05-29
ES2112988T3 (es)	1998-04-16
DE69333187T2 (de)	2004-07-15
DE69316760D1 (de)	1998-03-05
ES2206619T3 (es)	2004-05-16
MX9304585A (es)	1994-03-31
EP0775484A1 (de)	1997-05-28
DK0658101T3 (da)	1998-09-21
DE69316760T2 (de)	1998-06-04
EP0658101B1 (de)	1998-01-28
CN1052401C (zh)	2000-05-17
DE69333187D1 (de)	2003-10-09

Legal Events

Date	Code	Title	Description
1998-09-15	UEP	Publication of translation of european patent specification
2010-04-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE69333187D1 (de)	2003-10-09	Oberflächenaktivmittelfreie Aerosolformulierungen enthaltend Beclomethasondipropionat
DK0656206T3 (da)	2001-10-08	Aerosolformuleringer uden chlorfluorcarbonforbindelser
ATE99941T1 (de)	1994-01-15	Medikamente enthaltend salmeterol und fluticason.
ATE336268T1 (de)	2006-09-15	Medizinische aerosolzubereitung
AU4260496A (en)	1996-07-03	Propellant mixture for aerosol formulation
GEP20002253B (en)	2000-10-25	Pharmaceutical Aerosol Formulation, Proportioning Inhalator and Method for Treatment of Respiratory Diseases
FR2651678B1 (fr)	1992-04-30	Composition pharmaceutique a base de salmeterol et de dipropionate de beclometasone.
IL81472A0 (en)	1987-09-16	Stabilized formulations of alpha-interferon
IL68456A0 (en)	1983-07-31	Pharmaceutical compositions comprising perfluorohydrocarbons as vehicles
IE781032L (en)	1978-11-25	Pharmaceutical compositions
FI944535A0 (fi)	1994-09-29	Rapamysiinikoostumuksia oraalisesti annettaviksi
ES8705763A1 (es)	1987-06-01	Procedimiento para preparar nuevas formulaciones de gel parafines terapeuticos y diagnosticos
GB2021409A (en)	1979-12-05	Pharmaceutical composition
FR2691149B1 (fr)	1994-07-08	Nouveaux composes thiochromaniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
FR2694005B1 (fr)	1994-08-26	Nouvelles aminoalkylchromones, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent.
FR2691967B1 (fr)	1995-06-09	Nouveaux composes pyrrolothienopyraziniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
IT1251660B (it)	1995-05-19	Formulazioni per supposte a base di calcitonina