ATE162801T1 - Tnf(tumor necrosis factor)-inhibitor und verfahren zur herstellung - Google Patents

Tnf(tumor necrosis factor)-inhibitor und verfahren zur herstellung

Info

Publication number
ATE162801T1
ATE162801T1 AT90113673T AT90113673T ATE162801T1 AT E162801 T1 ATE162801 T1 AT E162801T1 AT 90113673 T AT90113673 T AT 90113673T AT 90113673 T AT90113673 T AT 90113673T AT E162801 T1 ATE162801 T1 AT E162801T1
Authority
AT
Austria
Prior art keywords
tnf
inhibitor
40kda
necrosis factor
tumor necrosis
Prior art date
Application number
AT90113673T
Other languages
English (en)
Inventor
Michael T Brewer
Karin K Hale
Michael W King
Tadahiko Kohno
Charles Squires
Robert C Thompson
Rebecca W Vanderslice
James Vannice
Original Assignee
Amgen Boulder Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27409520&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE162801(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Boulder Inc filed Critical Amgen Boulder Inc
Application granted granted Critical
Publication of ATE162801T1 publication Critical patent/ATE162801T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02—Peptides being immobilised on, or in, an organic carrier
    • C07K17/06—Peptides being immobilised on, or in, an organic carrier attached to the carrier via a bridging agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
AT90113673T 1989-07-18 1990-07-17 Tnf(tumor necrosis factor)-inhibitor und verfahren zur herstellung ATE162801T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38108089A 1989-07-18 1989-07-18
US45032989A 1989-12-11 1989-12-11
US47966190A 1990-02-07 1990-02-07

Publications (1)

Publication Number Publication Date
ATE162801T1 true ATE162801T1 (de) 1998-02-15

Family

ID=27409520

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90113673T ATE162801T1 (de) 1989-07-18 1990-07-17 Tnf(tumor necrosis factor)-inhibitor und verfahren zur herstellung

Country Status (20)

Country Link
US (1) US6541620B1 (de)
EP (2) EP0422339B1 (de)
JP (1) JPH03163099A (de)
KR (1) KR100230156B1 (de)
AT (1) ATE162801T1 (de)
AU (1) AU647397B2 (de)
CA (1) CA2021369A1 (de)
DE (1) DE69031997T2 (de)
DK (1) DK0422339T3 (de)
ES (1) ES2116970T3 (de)
FI (1) FI114398B (de)
GR (1) GR3026416T3 (de)
IE (2) IE990595A1 (de)
IL (2) IL95031A (de)
NO (1) NO306728B1 (de)
NZ (1) NZ234499A (de)
PL (1) PL168844B1 (de)
PT (1) PT94754B (de)
SG (1) SG55131A1 (de)
TW (1) TW206234B (de)

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EP0480389A1 (de) * 1990-10-12 1992-04-15 Hoechst Aktiengesellschaft Inhibitoren für die Bildung von Tumor Nekrose Faktor, Verfahren zu deren Herstellung und deren Verwendung
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US5747639A (en) * 1996-03-06 1998-05-05 Amgen Boulder Inc. Use of hydrophobic interaction chromatography to purify polyethylene glycols
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ATE247974T1 (de) 1996-12-06 2003-09-15 Amgen Inc Kombinationtherapie mit einem tnf-bindendem protein zür behandlung von durch tnf verursachten erkrangungen
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US8795668B2 (en) * 2005-12-23 2014-08-05 The Regents Of The University Of Michigan Methods for treating pulmonary fibrosis
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Also Published As

Publication number Publication date
KR910015309A (ko) 1991-09-30
NZ234499A (en) 1992-08-26
FI903591A0 (fi) 1990-07-16
FI114398B (fi) 2004-10-15
PT94754B (pt) 1997-04-30
NO306728B1 (no) 1999-12-13
EP0422339B1 (de) 1998-01-28
GR3026416T3 (en) 1998-06-30
EP0422339A1 (de) 1991-04-17
EP0790306A3 (de) 1998-07-01
NO306728B3 (de) 2003-02-17
AU5897690A (en) 1991-01-24
PL286089A1 (en) 1991-07-29
ES2116970T3 (es) 1998-08-01
IL95031A0 (en) 1991-06-10
NO903192D0 (no) 1990-07-17
KR100230156B1 (ko) 1999-11-15
CA2021369A1 (en) 1991-01-19
HK1014539A1 (en) 1999-09-30
NO903192L (no) 1991-01-21
TW206234B (de) 1993-05-21
IL95031A (en) 2007-03-08
IL131281A0 (en) 2001-01-28
IE902608A1 (en) 1991-02-27
DE69031997T2 (de) 1998-05-14
DE69031997D1 (de) 1998-03-05
PL168844B1 (pl) 1996-04-30
SG55131A1 (en) 1998-12-21
IE990595A1 (en) 2000-11-15
AU647397B2 (en) 1994-03-24
EP0790306A2 (de) 1997-08-20
DK0422339T3 (da) 1998-09-23
JPH03163099A (ja) 1991-07-15
PT94754A (pt) 1991-03-20
US6541620B1 (en) 2003-04-01

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