ATE164587T1 - Sialinsauer-amide von 3-aminosterinen - Google Patents

Sialinsauer-amide von 3-aminosterinen

Info

Publication number: ATE164587T1
Authority: AT; Austria
Prior art keywords: sialic acid; acyl; alkyl; aminosterols; acid amides
Prior art date: 1993-12-24

Application number

AT94120538T

Other languages

English (en)

Inventor

Haruyuki Chaki

Naoko Ando

Aoba-Ku Kamoshida-Cho

Yasuhiro Morinaka

Ken-Ichi Saito

Tomoko Yugami

Rie Yoshida

Original Assignee

Mitsubishi Chem Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-12-24

Filing date

1994-12-23

Publication date

1998-04-15

1994-12-23 Application filed by Mitsubishi Chem Corp filed Critical Mitsubishi Chem Corp

1998-04-15 Application granted granted Critical

1998-04-15 Publication of ATE164587T1 publication Critical patent/ATE164587T1/de

Links

SQVRNKJHWKZAKO-OQPLDHBCSA-N sialic acid Chemical compound CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)OC1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-OQPLDHBCSA-N 0.000 title abstract 3
SQVRNKJHWKZAKO-UHFFFAOYSA-N beta-N-Acetyl-D-neuraminic acid Natural products CC(=O)NC1C(O)CC(O)(C(O)=O)OC1C(O)C(O)CO SQVRNKJHWKZAKO-UHFFFAOYSA-N 0.000 title 1
125000002252 acyl group Chemical group 0.000 abstract 3
125000000217 alkyl group Chemical group 0.000 abstract 3
208000024827 Alzheimer disease Diseases 0.000 abstract 2
102100023460 Choline O-acetyltransferase Human genes 0.000 abstract 1
108010058699 Choline O-acetyltransferase Proteins 0.000 abstract 1
206010039966 Senile dementia Diseases 0.000 abstract 1
210000002932 cholinergic neuron Anatomy 0.000 abstract 1
150000001875 compounds Chemical group 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
150000004677 hydrates Chemical class 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000012453 solvate Substances 0.000 abstract 1
230000003637 steroidlike Effects 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
- C07H7/04—Carbocyclic radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J17/005—Glycosides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Psychiatry (AREA)
Pharmacology & Pharmacy (AREA)
Hospice & Palliative Care (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Saccharide Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT94120538T 1993-12-24 1994-12-23 Sialinsauer-amide von 3-aminosterinen ATE164587T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP32845493		1993-12-24

Publications (1)

Publication Number	Publication Date
ATE164587T1 true ATE164587T1 (de)	1998-04-15

Family

ID=18210456

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT94120538T ATE164587T1 (de)	1993-12-24	1994-12-23	Sialinsauer-amide von 3-aminosterinen

Country Status (10)

Country	Link
US (1)	US5712254A (de)
EP (1)	EP0659762B1 (de)
KR (1)	KR100365660B1 (de)
CN (1)	CN1056152C (de)
AT (1)	ATE164587T1 (de)
CA (1)	CA2138839C (de)
DE (1)	DE69409338T2 (de)
DK (1)	DK0659762T3 (de)
ES (1)	ES2115856T3 (de)
TW (1)	TW479061B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE69515101T2 (de) *	1994-05-27	2000-07-13	Daikin Industries, Ltd.	7-fluoro-2,3-didehydrosialinsäure und zwischenprodukte in ihrer synthese
WO1997000885A1 (fr) *	1995-06-23	1997-01-09	Mitsubishi Chemical Corporation	Derives d'acide sialique
CN1064048C (zh) *	1996-08-29	2001-04-04	中国科学院昆明植物研究所	青阳参甙丙至甙庚五个化合物及其制备方法和应用
EP1438387A4 (de) *	2001-09-14	2004-10-13	Momenta Pharmaceuticals Inc	Verfahren zur herstellung von glycomolekülen mit verstärkten aktivitäten und verwendungen davon
KR20100093621A (ko) *	2002-03-27	2010-08-25	파이토팜 피엘씨	사포게닌 및 그 유도체의 치료 방법 및 용도
JP2010524467A (ja)	2007-04-16	2010-07-22	モメンタファーマシューティカルズインコーポレイテッド	規定の糖タンパク質産物および関連の方法
WO2009123877A1 (en) *	2008-03-21	2009-10-08	Braincells, Inc.	A method of treating a nervous system disorder by modulation of neurogenesis with mcc-257
WO2011127322A1 (en)	2010-04-07	2011-10-13	Momenta Pharmaceuticals, Inc.	High mannose glycans
EP2686671A4 (de)	2011-03-12	2015-06-24	Momenta Pharmaceuticals Inc	N-acetylhexosamin-haltige n-glykane in glycoproteinprodukten
WO2013181575A2 (en)	2012-06-01	2013-12-05	Momenta Pharmaceuticals, Inc.	Methods related to denosumab
CN102796151A (zh) *	2012-07-27	2012-11-28	珠海迪尔生物工程有限公司	基于茜素染料的α-D-N-乙酰神经氨酸苷化合物及其制备方法与应用
EP3370764A4 (de) *	2015-11-05	2019-07-17	The Regents of The University of California	Mit lipidkonjugaten markierte zellen und verfahren zur verwendung davon
CN118141023B (zh) *	2024-04-29	2024-12-27	山东德杰康生物科技有限公司	一种含燕窝酸和茶多酚的饮料及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS60231690A (ja) *	1984-05-01	1985-11-18	Kanto Ishi Pharma Co Ltd	Ｎ―置換ノイラミン酸誘導体
JPH07116209B2 (ja) *	1986-04-11	1995-12-13	メクト株式会社	シアロシルセラミド類及びその製造方法
JPS63264493A (ja) *	1986-12-29	1988-11-01	Mect Corp	活性カルボニル基を持つシアル酸誘導体
US5177062A (en) *	1988-08-09	1993-01-05	Mect Corporation	Method for treating immune complex diseases with n-acetylneuraminic acid
US5104856A (en) *	1990-11-09	1992-04-14	Uab Research Foundation	Heparan sulfate biosynthesis primers
JP3286340B2 (ja) *	1991-03-06	2002-05-27	日本臓器製薬株式会社	シアル酸誘導体
US5438125A (en) *	1991-03-06	1995-08-01	Nippon Zoki Pharmaceutical Co., Ltd.	Sialic acid derivatives
JPH0592991A (ja) *	1991-03-27	1993-04-16	Mitsubishi Kasei Corp	チオシアル酸誘導体
IT1260156B (it) *	1992-08-03	1996-03-28	Fidia Spa	Derivati dell'acido neuraminico
US5506221A (en) *	1992-12-24	1996-04-09	University Of British Columbia	Contignasterol, and related 3-alpha hydroxy-6-alpha hydroxy-7-beta hydroxy-15-keto-14-beta steroids useful as anti-inflammatory and anti-thrombosis agents
JPH09181287A (ja) *	1995-10-24	1997-07-11	Sony Corp	受光装置とその製造方法

1994
- 1994-12-20 TW TW083111930A patent/TW479061B/zh active
- 1994-12-21 KR KR1019940035668A patent/KR100365660B1/ko not_active Expired - Fee Related
- 1994-12-22 CA CA002138839A patent/CA2138839C/en not_active Expired - Fee Related
- 1994-12-23 DE DE69409338T patent/DE69409338T2/de not_active Expired - Lifetime
- 1994-12-23 EP EP94120538A patent/EP0659762B1/de not_active Expired - Lifetime
- 1994-12-23 DK DK94120538T patent/DK0659762T3/da active
- 1994-12-23 AT AT94120538T patent/ATE164587T1/de active
- 1994-12-23 ES ES94120538T patent/ES2115856T3/es not_active Expired - Lifetime
- 1994-12-23 US US08/362,947 patent/US5712254A/en not_active Expired - Lifetime
- 1994-12-24 CN CN94119256A patent/CN1056152C/zh not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CN1108260A (zh)	1995-09-13
DE69409338T2 (de)	1998-09-03
KR950018037A (ko)	1995-07-22
EP0659762A2 (de)	1995-06-28
KR100365660B1 (ko)	2003-04-11
TW479061B (en)	2002-03-11
DK0659762T3 (da)	1998-10-19
DE69409338D1 (de)	1998-05-07
ES2115856T3 (es)	1998-07-01
US5712254A (en)	1998-01-27
CA2138839A1 (en)	1995-06-25
EP0659762A3 (de)	1995-12-13
EP0659762B1 (de)	1998-04-01
CA2138839C (en)	2005-06-28
CN1056152C (zh)	2000-09-06

Legal Events

Date	Code	Title	Description
1998-12-15	UEP	Publication of translation of european patent specification

Publication	Publication Date	Title
GR75353B (de)	1984-07-13
HU913436D0 (en)	1992-01-28	Process for the production of amino-cumarane-derivatives and medical preparations containing them
ATE164587T1 (de)	1998-04-15	Sialinsauer-amide von 3-aminosterinen
TW225529B (de)	1994-06-21
DE69027180D1 (de)	1996-07-04	4-Acylaminopyridin-Derivate
ES2055235T3 (es)	1994-08-16	Composicion anti-inflamatoria y/o antialergica que comprende derivados de glutation.
HUT75647A (en)	1997-05-28	Imidazolidinone derivatives and pharmaceutical compositions containing them, which are suitable for treament of senile dementia
HU906010D0 (en)	1991-03-28	New substituted alkyl-piperidine derivatives
DE69001004D1 (de)	1993-04-08	Zusammensetzung gegen leberkrankheiten.
EP0802179A4 (de)	2000-04-05	Derivate substituierter amidinonaphthylester
ES2149180T3 (es)	2000-11-01	Derivado de pirazolotiazolopirimidina.