ATE164678T1 - Zusammensetzung zur behandlung der senilen demenz - Google Patents
Zusammensetzung zur behandlung der senilen demenzInfo
- Publication number
- ATE164678T1 ATE164678T1 AT90903065T AT90903065T ATE164678T1 AT E164678 T1 ATE164678 T1 AT E164678T1 AT 90903065 T AT90903065 T AT 90903065T AT 90903065 T AT90903065 T AT 90903065T AT E164678 T1 ATE164678 T1 AT E164678T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- ginsenosides
- acetylcholine
- sec
- mixture
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 206010012289 Dementia Diseases 0.000 title 1
- 229930182494 ginsenoside Natural products 0.000 abstract 3
- OIPILFWXSMYKGL-UHFFFAOYSA-N acetylcholine Chemical compound CC(=O)OCC[N+](C)(C)C OIPILFWXSMYKGL-UHFFFAOYSA-N 0.000 abstract 2
- 229960004373 acetylcholine Drugs 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 229940122041 Cholinesterase inhibitor Drugs 0.000 abstract 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 1
- 210000004556 brain Anatomy 0.000 abstract 1
- 239000000544 cholinesterase inhibitor Substances 0.000 abstract 1
- 238000004587 chromatography analysis Methods 0.000 abstract 1
- 230000001054 cortical effect Effects 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 230000000971 hippocampal effect Effects 0.000 abstract 1
- 230000002503 metabolic effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000005192 partition Methods 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 239000000741 silica gel Substances 0.000 abstract 1
- 229910002027 silica gel Inorganic materials 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J17/005—Glycosides
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pest Control & Pesticides (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Agronomy & Crop Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/297,012 US4966893A (en) | 1989-01-13 | 1989-01-13 | Method for treatment of senile dementia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE164678T1 true ATE164678T1 (de) | 1998-04-15 |
Family
ID=23144493
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90903065T ATE164678T1 (de) | 1989-01-13 | 1990-01-12 | Zusammensetzung zur behandlung der senilen demenz |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US4966893A (de) |
| EP (1) | EP0453515B1 (de) |
| JP (1) | JPH04504414A (de) |
| KR (1) | KR0160104B1 (de) |
| AT (1) | ATE164678T1 (de) |
| AU (1) | AU5085990A (de) |
| CA (1) | CA2046328A1 (de) |
| DE (1) | DE69032201D1 (de) |
| WO (1) | WO1990008315A1 (de) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4966893A (en) * | 1989-01-13 | 1990-10-30 | Pang Peter K T | Method for treatment of senile dementia |
| US5589182A (en) * | 1993-12-06 | 1996-12-31 | Tashiro; Renki | Compositions and method of treating cardio-, cerebro-vascular and alzheimer's diseases and depression |
| JPH10500937A (ja) * | 1994-02-25 | 1998-01-27 | ニュー イングランド ディーコネス ホスピタル コーポレイション | セサミン系リグナンの抗炎症及び感染防護効果 |
| US5397778A (en) * | 1994-02-25 | 1995-03-14 | New England Deaconess Hospital Corporation | Enteral formulations for treatment of inflammation and infection |
| ES2097703B1 (es) | 1995-04-12 | 1997-12-01 | Decox S L | Una nueva composicion estimulante de la actividad cerebral basada en alcaloides de nucleo de eburnamenina, y sus metodos de preparacion. |
| US6083932A (en) * | 1997-04-18 | 2000-07-04 | Cv Technologies Inc. | Pharmaceutical compositions derived from ginseng and methods of treatment using same |
| US5770217A (en) * | 1997-07-02 | 1998-06-23 | Atlatl, Inc. | Dietary supplement for hematological, immune and appetite enhancement |
| KR20000006625A (ko) * | 1998-07-20 | 2000-02-07 | 묵인희 | 인삼추출물을 포함하는 치매 치료제 |
| US6132726A (en) * | 1998-10-21 | 2000-10-17 | Hauser, Inc. | Process for removing impurities from natural product extracts |
| JP2000191539A (ja) * | 1998-12-22 | 2000-07-11 | Japan Science & Technology Corp | ジンセノサイドRb1からなる脳細胞又は神経細胞保護剤 |
| JP2000302798A (ja) * | 1999-02-19 | 2000-10-31 | Japan Science & Technology Corp | ジンセノサイドRb1からなる脳血管再生・再構築促進剤ならびに神経組織二次変性抑止剤 |
| JP4759776B2 (ja) * | 1999-04-01 | 2011-08-31 | 大正製薬株式会社 | 液体組成物 |
| KR20020035855A (ko) * | 1999-08-30 | 2002-05-15 | 마쯔오 미쯔요시 | 약용인삼을 포함하는 뇌세포 또는 신경세포 보호제 |
| JP2001139483A (ja) * | 1999-08-30 | 2001-05-22 | Japan Science & Technology Corp | 薬用人蔘からなる脳細胞または神経細胞保護剤 |
| KR100375018B1 (ko) * | 2000-01-31 | 2003-03-06 | (주) 디지탈바이오텍 | 인삼 추출물을 함유하는 뇌의 해마 시냅스 형성 촉진제 |
| CA2307393A1 (en) | 2000-05-01 | 2001-11-01 | The University Of British Columbia | Ginsenoside chemotherapy |
| WO2001092289A1 (en) * | 2000-05-31 | 2001-12-06 | Japan Science And Technology Corporation | SKIN TISSUE REGENERATION PROMOTERS COMPRISING GINSENOSIDE Rb1 |
| US6888014B2 (en) * | 2001-07-24 | 2005-05-03 | Panagin Pharmaceuticals Inc. | Dammarane sapogenins, their use as anti-cancer agents, and a process for producing same |
| US20050233984A1 (en) * | 2002-05-16 | 2005-10-20 | Digital Biotech Co., Ltd. | Composition for preventing or treating degenerative brain diseases comprising a hydrolysate of ginsenosides |
| US20050245465A1 (en) * | 2004-04-28 | 2005-11-03 | Tae-Wan Kim | Compounds for treating Alzheimer's disease and for inhibiting beta-amyloid peptitde production |
| US20060014704A1 (en) * | 2004-07-16 | 2006-01-19 | Landry Donald W | Compounds and their preparation for the treatment of Alzheimer's disease by inhibiting beta-amyloid peptide production |
| US8855759B2 (en) * | 2007-10-09 | 2014-10-07 | The Hong Kong Polytechnic University | Method of treating a rheumatic disorder using combination of transcutaneous electrical nerve stimulation and a ginsenoside |
| EP2254569B1 (de) | 2008-01-24 | 2012-11-28 | Raptor Therapeutics Inc. | Ginsenosid-zusammensetzungen vom protopanaxadiol-typ und ihre verwendungen |
| US20120283193A1 (en) * | 2009-10-31 | 2012-11-08 | The Regents Of The University Of California | Manipulation of brain in a circuit-specific manner |
| JP5563285B2 (ja) * | 2009-12-14 | 2014-07-30 | ライオン株式会社 | 飲食品、医薬品、又は医薬部外品、並びに、プロトパナキサトリオールの安定化方法、及びプロトパナキサジオールの安定化方法 |
| BE1027772B1 (fr) | 2019-11-21 | 2021-06-21 | Botalys Sa | Composition de ginseng pour ameliorer l'etat de la peau et son utilisation pour le traitement d'une maladie dermatologique |
| BE1027552B1 (fr) | 2019-09-03 | 2021-03-30 | Botalys Sa | Composition du ginseng et son utilisation comme medicament pour le traitement ou la prevention du stress |
| WO2021043389A1 (en) | 2019-09-03 | 2021-03-11 | Botalys Sa | Ginseng composition and use thereof as a medicament for treatment or prevention of an impaired cognition |
| JP2022553120A (ja) | 2019-09-03 | 2022-12-22 | ボタリス エスアー | ニンジン組成物及び医薬としてのその使用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1574806A (en) * | 1976-06-03 | 1980-09-10 | Inverni Della Beffa Spa | Production of purified ginseng extracts and pharmaceutical compositions containing the extracts |
| JPS5626818A (en) * | 1979-08-13 | 1981-03-16 | Osaka Chem Lab | Glucocorticoid drug |
| DE3042117A1 (de) * | 1980-03-11 | 1981-09-24 | Arichi, Shigeru, Toyonaka, Osaka | Gynosaponine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneipraeparate |
| JPS56147719A (en) * | 1980-04-18 | 1981-11-16 | Meiji Seika Kaisha Ltd | Production of dried ginseng |
| JPS59118053A (ja) * | 1982-12-24 | 1984-07-07 | Hayashibara Biochem Lab Inc | 飲食物とその製造方法 |
| US4684628A (en) * | 1985-05-03 | 1987-08-04 | Yaguang Liu | Pharmaceutical composition containing pure San-Mai-Sen |
| US4687761A (en) * | 1985-05-09 | 1987-08-18 | Yaguang Liu | Pharmaceutical composition for increasing immunity and decreasing side effects of anticancer chemotherapy |
| US4647460A (en) * | 1985-09-06 | 1987-03-03 | Jeoungkyu Lee | Composition and method for narcotics withdrawal |
| US4755504A (en) * | 1985-10-03 | 1988-07-05 | Yaguang Liu | Pharmaceutical composition from Tienchi |
| US4814339A (en) * | 1986-02-11 | 1989-03-21 | Advanced Biologics, Inc. | Treatment for Alzheimer's disease |
| US4847082A (en) * | 1987-01-21 | 1989-07-11 | Robert Sabin | Method of treatment of Alzheimer's disease using phytic acid |
| JPH0813741B2 (ja) * | 1987-08-10 | 1996-02-14 | 協和醗酵工業株式会社 | 抗痴呆剤 |
| US5071839A (en) * | 1987-11-02 | 1991-12-10 | Yaguang Liu | Safe pharmaceutical composition for decreasing side effects of antiviral drugs and increasing the immune function (SDI) II |
| US4837219A (en) * | 1987-11-05 | 1989-06-06 | Jeffrey Hutterer | Medication for Alzheimer's disease |
| US4966893A (en) * | 1989-01-13 | 1990-10-30 | Pang Peter K T | Method for treatment of senile dementia |
-
1989
- 1989-01-13 US US07/297,012 patent/US4966893A/en not_active Expired - Lifetime
-
1990
- 1990-01-12 AU AU50859/90A patent/AU5085990A/en not_active Abandoned
- 1990-01-12 WO PCT/US1990/000121 patent/WO1990008315A1/en not_active Ceased
- 1990-01-12 DE DE69032201T patent/DE69032201D1/de not_active Expired - Lifetime
- 1990-01-12 JP JP2503238A patent/JPH04504414A/ja active Pending
- 1990-01-12 KR KR1019900702023A patent/KR0160104B1/ko not_active Expired - Fee Related
- 1990-01-12 AT AT90903065T patent/ATE164678T1/de not_active IP Right Cessation
- 1990-01-12 US US07/768,423 patent/US5137878A/en not_active Expired - Lifetime
- 1990-01-12 EP EP90903065A patent/EP0453515B1/de not_active Expired - Lifetime
- 1990-01-12 CA CA002046328A patent/CA2046328A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU5085990A (en) | 1990-08-13 |
| US4966893A (en) | 1990-10-30 |
| US5137878A (en) | 1992-08-11 |
| KR0160104B1 (ko) | 1999-03-30 |
| JPH04504414A (ja) | 1992-08-06 |
| EP0453515A1 (de) | 1991-10-30 |
| EP0453515A4 (en) | 1992-05-06 |
| WO1990008315A1 (en) | 1990-07-26 |
| EP0453515B1 (de) | 1998-04-01 |
| DE69032201D1 (de) | 1998-05-07 |
| CA2046328A1 (en) | 1990-07-14 |
| KR910700454A (ko) | 1991-03-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |