ATE164828T1 - 3,3-diphenylpropylamine, ihre verwendung und herstellung - Google Patents
3,3-diphenylpropylamine, ihre verwendung und herstellungInfo
- Publication number
- ATE164828T1 ATE164828T1 AT93924876T AT93924876T ATE164828T1 AT E164828 T1 ATE164828 T1 AT E164828T1 AT 93924876 T AT93924876 T AT 93924876T AT 93924876 T AT93924876 T AT 93924876T AT E164828 T1 ATE164828 T1 AT E164828T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- methyl
- formula
- diphenylpropylamines
- relates
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- -1 methoxy, hydroxy, carbamoyl Chemical group 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- KISZTEOELCMZPY-UHFFFAOYSA-N 3,3-diphenylpropylamine Chemical class C=1C=CC=CC=1C(CCN)C1=CC=CC=C1 KISZTEOELCMZPY-UHFFFAOYSA-N 0.000 abstract 1
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001302 tertiary amino group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
- C07C217/62—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
- C07C215/54—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Luminescent Compositions (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Photoreceptors In Electrophotography (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9203318A SE9203318D0 (sv) | 1992-11-06 | 1992-11-06 | Novel 3,3-diphenylpropylamines, their use and preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE164828T1 true ATE164828T1 (de) | 1998-04-15 |
Family
ID=20387730
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93924876T ATE164828T1 (de) | 1992-11-06 | 1993-11-05 | 3,3-diphenylpropylamine, ihre verwendung und herstellung |
Country Status (14)
| Country | Link |
|---|---|
| US (4) | USRE40851E1 (de) |
| EP (1) | EP0667852B1 (de) |
| JP (1) | JP3343256B2 (de) |
| AT (1) | ATE164828T1 (de) |
| AU (1) | AU672458B2 (de) |
| CA (1) | CA2148827C (de) |
| DE (1) | DE69317898T2 (de) |
| DK (1) | DK0667852T3 (de) |
| ES (1) | ES2117155T3 (de) |
| FI (1) | FI120256B (de) |
| HU (1) | HU224916B1 (de) |
| NO (1) | NO305477B1 (de) |
| SE (1) | SE9203318D0 (de) |
| WO (1) | WO1994011337A1 (de) |
Families Citing this family (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9203318D0 (sv) * | 1992-11-06 | 1992-11-06 | Kabi Pharmacia Ab | Novel 3,3-diphenylpropylamines, their use and preparation |
| WO1998000140A1 (en) * | 1996-07-01 | 1998-01-08 | Sepracor, Inc. | Methods and compositions for treating urinary incontinence using enantiomerically enriched (r)-trihexyphenidyl |
| JP4167302B2 (ja) * | 1996-12-02 | 2008-10-15 | 杏林製薬株式会社 | 新規ｎ―置換ピロリジン誘導体及びその製造法 |
| SE9701144D0 (sv) * | 1997-03-27 | 1997-03-27 | Pharmacia & Upjohn Ab | Novel compounds, their use and preparation |
| EP0957073A1 (de) | 1998-05-12 | 1999-11-17 | Schwarz Pharma Ag | 3,3-Diphenylpropylaminderivate |
| CA2311755C (en) | 1998-08-27 | 2010-03-23 | Pharmacia & Upjohn Ab | Therapeutic formulation for administering tolterodine with controlled release |
| MXPA02004574A (es) | 1999-11-11 | 2004-09-10 | Pharmacia Ab | Formulacion farmaceutica que contiene tolterodina y su uso. |
| DE29923134U1 (de) | 1999-11-16 | 2000-06-29 | Schwarz Pharma Ag, 40789 Monheim | Stabile Salze neuartiger Derviate von 3,3-Diphenylpropylaminen |
| SE9904850D0 (sv) * | 1999-12-30 | 1999-12-30 | Pharmacia & Upjohn Ab | Novel process and intermediates |
| US6790854B2 (en) | 2000-03-24 | 2004-09-14 | Meiji Seika Kaisha, Ltd. | Diphenylalkylamine derivatives useful as opioid receptor agonists |
| DE10028443C1 (de) * | 2000-06-14 | 2002-05-29 | Sanol Arznei Schwarz Gmbh | Verfahren zur Herstellung von 3,3-Diarylpropylaminen, (R,S)- und (R)-4-Phenyl-2-chromanon-6-carbonsäure sowie (R)-4-Phenyl-2-chromanon-carbonsäure-cinchonidinsalz und deren Verwendung zur Herstellung eines rechtsdrehenden Hydroxybenzylalkohols und von pharmazeutischen Zusammensetzungen |
| DE10033016A1 (de) | 2000-07-07 | 2002-01-24 | Sanol Arznei Schwarz Gmbh | Verfahren zur Herstellung von 3,3-Diarylpropylaminen |
| PE20020547A1 (es) | 2000-10-24 | 2002-06-12 | Upjohn Co | Uso de la tolterodina en tratamientos del asma |
| CN1536986B (zh) * | 2001-03-27 | 2012-07-04 | 沃纳奇尔科特(爱尔兰)有限公司 | 用于抗微生物剂给药的阴道内药物递送装置 |
| US20030027856A1 (en) * | 2001-06-29 | 2003-02-06 | Aberg A.K. Gunnar | Tolterodine metabolites |
| US20030060513A1 (en) * | 2001-09-27 | 2003-03-27 | Arneric Stephen P. | Pharmaceutical composition |
| EP1461306B1 (de) * | 2001-10-26 | 2008-12-24 | Pharmacia & Upjohn Company LLC | Quaternäre ammoniumverbindungen und deren verwendung als antimuscarinische wirkstoffe |
| JP2005511582A (ja) * | 2001-11-05 | 2005-04-28 | ファルマシア アンド アップジョン カンパニー リミティド ライアビリティー カンパニー | 抗ムスカリン・エアゾール |
| MXPA04003866A (es) * | 2001-11-09 | 2004-07-08 | Pharmacia Ab | Agente-antimuscarnico y agonista de estrogeno para tratar la vejiga inestable o hiperactiva. |
| WO2003053428A1 (en) * | 2001-12-20 | 2003-07-03 | Pharmacia Corporation | Controlled release dosage form having improved drug release properties |
| IL163666A0 (en) | 2002-02-22 | 2005-12-18 | New River Pharmaceuticals Inc | Active agent delivery systems and methods for protecting and administering active agents |
| US7005449B2 (en) | 2002-04-23 | 2006-02-28 | Pharmacia & Upjohn Company | Tolterodine salts |
| DE60230683D1 (de) * | 2002-07-08 | 2009-02-12 | Ranbaxy Lab Ltd | 3,6-disubstituierte azabicyclo-3.1.0 hexan-derivat |
| US7825132B2 (en) | 2002-08-23 | 2010-11-02 | Novartis Vaccines And Diagnostics, Inc. | Inhibition of FGFR3 and treatment of multiple myeloma |
| MXPA05004754A (es) | 2002-11-13 | 2005-08-02 | Chiron Corp | Metodos para tratar cancer y metodos relacionados. |
| DE10315917A1 (de) * | 2003-04-08 | 2004-11-18 | Schwarz Pharma Ag | Hochreine Basen von 3,3-Diphenylpropylaminmonoestern |
| US7517905B2 (en) * | 2003-04-09 | 2009-04-14 | Ranbaxy Laboratories Limited | Substituted azabicyclo hexane derivatives as muscarinic receptor antagonists |
| CA2522071A1 (en) * | 2003-04-11 | 2004-10-21 | Ranbaxy Laboratories Limited | Azabicyclo derivatives as muscarinic receptor antagonists |
| MXPA05011509A (es) | 2003-04-25 | 2005-12-15 | Pharmacia & Upjohn Co Llc | 3,3-difenilpropilaminas (tolterodina) sustituidas con halogenos que presentan actividad antimuscarinica. |
| EP1633695B1 (de) * | 2003-05-23 | 2012-02-15 | Bridge Pharma, Inc. | Glattmuskelspasmolytika |
| WO2005012227A2 (en) * | 2003-08-05 | 2005-02-10 | Ranbaxy Laboratories Limited | Process for preparation of 2-(3-diisopropylamino-1-phenylpropyl)-4-hydroxymethyl-phenol, a metabolite of tolterodine |
| ES2235648B1 (es) * | 2003-12-22 | 2006-11-01 | Ragactives, S.L. | Procedimiento para la obtencion de tolterodina. |
| US7538249B2 (en) * | 2003-12-24 | 2009-05-26 | Cipla Limited | Tolterodine, compositions and uses thereof, and preparation of the same |
| US7875624B2 (en) | 2004-02-20 | 2011-01-25 | Novartis Vaccines And Diagnostics, Inc. | Modulating and measuring cellular adhesion |
| EP1629834A1 (de) | 2004-08-27 | 2006-03-01 | KRKA, D.D., Novo Mesto | Pharmazeutische Zusammensetzung von Tolterodin mit verzögerter Freisetzung |
| US20100035954A1 (en) * | 2004-12-15 | 2010-02-11 | Mohammad Salman | Acid addition salts of muscarinic receptor antagonists |
| WO2006074479A1 (en) * | 2005-01-10 | 2006-07-13 | Teva Pharmaceutical Industries, Ltd. | Process for preparing tolterodine tartrate |
| US20080319043A1 (en) * | 2005-05-03 | 2008-12-25 | Mohammad Salman | 3,6-Disubstituted Azabicyclo (3.1.0) Hexane Derivatives as Muscarinic Receptor Antagonists |
| CN101222850B (zh) | 2005-05-13 | 2012-10-03 | 诺瓦提斯公司 | 治疗对药物有抗性的癌症的方法 |
| WO2007072169A2 (en) * | 2005-12-20 | 2007-06-28 | Pfizer Products Inc. | Pharmaceutical combination for the treatment of luts comprising a pde5 inhibitor and a muscarinic antagonist |
| EA016203B1 (ru) | 2006-03-20 | 2012-03-30 | Пфайзер Лимитед | Производные амина |
| EP1862449A1 (de) * | 2006-05-31 | 2007-12-05 | Schwarz Pharma Ltd. | Verkürzte Synthese von substituierten Hydroxymethylphenolen |
| JP5257353B2 (ja) * | 2006-05-31 | 2013-08-07 | シュウォーツ ファーマ リミテッド | 置換ヒドロキシメチルフェノールの新規な合成 |
| IES20060424A2 (en) | 2006-06-08 | 2007-10-31 | Schwarz Pharma Ltd | Accelerated synthesis of (3-Diisopropylamino-1-phenylpropyl)-4-(hydroxymethyl)phenol and its phenolic monoesters |
| DE602007008389D1 (de) | 2006-06-09 | 2010-09-23 | Schwarz Pharma Ltd | Synthese von phenolischen estern von hydroxymethylphenolen |
| WO2007144097A1 (en) | 2006-06-12 | 2007-12-21 | Schwarz Pharma Ag | New chiral intermediate, process for producing the same and its use in the manufacture of tolterodine, fesoterodine, or the active metabolite thereof |
| IES20060435A2 (en) | 2006-06-12 | 2007-12-12 | Schwarz Pharma Ltd | Shortened synthesis using paraformaldehyde or trioxane |
| EP2044001B1 (de) | 2006-06-20 | 2016-11-23 | LEK Pharmaceuticals d.d. | Verfahren zur herstellung von 3-(2-hydroxy-5-substituiertes phenyl)-n-alkyl-3-phenylpropylaminen |
| US20100217034A1 (en) * | 2007-09-21 | 2010-08-26 | Actavis Group Ptc Ehf | Process for the Preparation of Fesoterodine |
| KR101188333B1 (ko) * | 2008-02-20 | 2012-10-09 | 에스케이케미칼주식회사 | 안정성이 우수하고 경피제로 유용한 톨테로딘 결정성산부가염 |
| US20090214665A1 (en) * | 2008-02-26 | 2009-08-27 | Lai Felix S | Controlled Release Muscarinic Receptor Antagonist Formulation |
| BRPI1010820A2 (pt) * | 2009-05-11 | 2019-09-24 | Ratiopharm Gmbh | desfesoterodina na forma de um sal de acido tartarico |
| IT1394219B1 (it) | 2009-05-15 | 2012-06-01 | Chemi Spa | Metodo di preparazione di fesoterodina fumarato di elevata purezza. |
| IT1394217B1 (it) | 2009-05-15 | 2012-06-01 | Chemi Spa | Metodo di preparazione di fesoterodina e/o fesoterodina fumarato. |
| SI2281801T1 (sl) | 2009-07-27 | 2014-04-30 | Crystal Pharma, S.A.U. | Postopek za pridobivanje 3,3-diphenilpropilamina |
| IT1396373B1 (it) * | 2009-10-29 | 2012-11-19 | Dipharma Francis Srl | Procedimento per la preparazione di fesoterodina. |
| IL210279A0 (en) | 2009-12-25 | 2011-03-31 | Dexcel Pharma Technologies Ltd | Extended release compositions for high solubility, high permeability acdtive pharmaceutical ingredients |
| EP2364966A1 (de) | 2010-03-09 | 2011-09-14 | LEK Pharmaceuticals d.d. | Verfahren zur Herstellung von 3-(2-hydroxy-5-substituierten phenyl)-3-phenylpropylaminen, Zwischenprodukte zur Herstellung von Hydroxytolterodin |
| WO2011141932A2 (en) | 2010-05-11 | 2011-11-17 | Intas Pharmaceuticals Limited | Process for preparation of phenolic monoesters of hydroxymethyl phenols |
| WO2011145019A1 (en) * | 2010-05-17 | 2011-11-24 | Orchid Chemicals And Pharmaceuticals Limited | Improved process for diphenylpropylamine derivatives |
| IT1401451B1 (it) | 2010-06-10 | 2013-07-26 | Chemi Spa | Nuovo processo di preparazione di 2-idrossi-4-fenil-3,4-diidro-2h-cromen-6-il-metanolo e (r)-2-[3-(diisopropilammino)-1-fenilpropil]-4-(idrossimetil)fenolo. |
| IT1403094B1 (it) | 2010-12-09 | 2013-10-04 | Dipharma Francis Srl | Procedimento per la preparazione di fesoterodina o un suo sale |
| TWI590821B (zh) | 2011-01-18 | 2017-07-11 | 輝瑞有限公司 | 固體分子分散液 |
| JP6234999B2 (ja) | 2012-05-04 | 2017-11-22 | クリスタル ファルマ、エセ、ア、ウＣｒｙｓｔａｌ Ｐｈａｒｍａ，Ｓ．Ａ．Ｕ． | 光学的に活性な３，３−ジフェニルプロピルアミンを調製するための方法 |
| PL2760822T3 (pl) | 2012-06-14 | 2016-09-30 | Sole desfezoterodyny | |
| ITMI20121232A1 (it) | 2012-07-16 | 2014-01-17 | Cambrex Profarmaco Milano Srl | Procedimento per la preparazione di 2-(3-n,n-diisopropilamino-1-fenilpropil)-4-idrossimetil-fenolo e suoi derivati |
| GB201402556D0 (en) | 2014-02-13 | 2014-04-02 | Crystec Ltd | Improvements relating to inhalable particles |
| WO2016148444A1 (ko) * | 2015-03-17 | 2016-09-22 | 제이더블유중외제약 주식회사 | 신규 데스페소테로딘 유도체, 이의 약제학적으로 허용되는 염 및 이를 포함하는 약제학적 조성물 |
| WO2017137955A1 (en) | 2016-02-14 | 2017-08-17 | Celestis Pharmaceuticals Pvt. Ltd. | Novel (r) and rac 3-(2-(allyloxy)-5-methylphenyl)-n,n-diisopropyl-3- phenylpropan-1-amine and its use for synthesis of (r) and rac-2-(3- (diisopropylamino)-1-phenylpropyl)-4-(hydroxymethyl)phenol |
| CN110372571B (zh) | 2018-04-12 | 2022-11-15 | 中国科学院大连化学物理研究所 | 一种2-(2,2-二芳基乙基)-环胺衍生物或盐及合成和应用与组合物 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK111894A (de) | 1962-11-15 | |||
| GB1169944A (en) * | 1966-08-25 | 1969-11-05 | Geistlich Soehne Ag | Novel 3,3-Diphenylpropylamines and processes for the preparation thereof |
| GB1169945A (en) | 1966-08-25 | 1969-11-05 | Geistlich Soehne Ag | Pharmaceutical Compositions containing Diphenylalkyl-amine Derivatives |
| US4139537A (en) | 1976-06-29 | 1979-02-13 | Cooper Laboratories, Inc. | 3-Aryloxy-1-(2- or 4-iminodihydro-1-pyridyl)-2-propanol antiarrhythmic compounds |
| SE8800207D0 (sv) | 1988-01-22 | 1988-01-22 | Kabivitrum Ab | Nya aminer, deras anvendning och framstellning |
| US5382600A (en) * | 1988-01-22 | 1995-01-17 | Pharmacia Aktiebolag | 3,3-diphenylpropylamines and pharmaceutical compositions thereof |
| SE9203318D0 (sv) * | 1992-11-06 | 1992-11-06 | Kabi Pharmacia Ab | Novel 3,3-diphenylpropylamines, their use and preparation |
| US5472958A (en) * | 1994-08-29 | 1995-12-05 | Abbott Laboratories | 2-((nitro)phenoxymethyl) heterocyclic compounds that enhance cognitive function |
| PE20020547A1 (es) * | 2000-10-24 | 2002-06-12 | Upjohn Co | Uso de la tolterodina en tratamientos del asma |
-
1992
- 1992-11-06 SE SE9203318A patent/SE9203318D0/xx unknown
-
1993
- 1993-11-05 CA CA002148827A patent/CA2148827C/en not_active Expired - Lifetime
- 1993-11-05 AT AT93924876T patent/ATE164828T1/de active
- 1993-11-05 DE DE69317898T patent/DE69317898T2/de not_active Expired - Lifetime
- 1993-11-05 US US11/402,337 patent/USRE40851E1/en not_active Expired - Lifetime
- 1993-11-05 ES ES93924876T patent/ES2117155T3/es not_active Expired - Lifetime
- 1993-11-05 DK DK93924876T patent/DK0667852T3/da active
- 1993-11-05 EP EP93924876A patent/EP0667852B1/de not_active Expired - Lifetime
- 1993-11-05 AU AU54380/94A patent/AU672458B2/en not_active Expired
- 1993-11-05 JP JP51197794A patent/JP3343256B2/ja not_active Expired - Lifetime
- 1993-11-05 HU HU9501329A patent/HU224916B1/hu unknown
- 1993-11-05 US US11/017,635 patent/USRE39667E1/en not_active Expired - Lifetime
- 1993-11-05 WO PCT/SE1993/000927 patent/WO1994011337A1/en not_active Ceased
-
1995
- 1995-05-05 FI FI952179A patent/FI120256B/fi not_active IP Right Cessation
- 1995-05-05 NO NO951775A patent/NO305477B1/no not_active IP Right Cessation
- 1995-05-05 US US08/432,113 patent/US5559269A/en not_active Ceased
-
1996
- 1996-07-22 US US08/684,638 patent/US5686464A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2117155T3 (es) | 1998-08-01 |
| JPH08503208A (ja) | 1996-04-09 |
| FI120256B (fi) | 2009-08-31 |
| SE9203318D0 (sv) | 1992-11-06 |
| NO951775D0 (no) | 1995-05-05 |
| CA2148827A1 (en) | 1994-05-26 |
| US5686464A (en) | 1997-11-11 |
| JP3343256B2 (ja) | 2002-11-11 |
| USRE39667E1 (en) | 2007-05-29 |
| AU672458B2 (en) | 1996-10-03 |
| EP0667852A1 (de) | 1995-08-23 |
| HU9501329D0 (en) | 1995-06-28 |
| EP0667852B1 (de) | 1998-04-08 |
| FI952179A0 (fi) | 1995-05-05 |
| USRE40851E1 (en) | 2009-07-14 |
| HU224916B1 (en) | 2006-04-28 |
| DE69317898D1 (de) | 1998-05-14 |
| HK1006349A1 (en) | 1999-02-19 |
| CA2148827C (en) | 2005-01-04 |
| NO951775L (no) | 1995-05-05 |
| HUT72742A (en) | 1996-05-28 |
| WO1994011337A1 (en) | 1994-05-26 |
| DK0667852T3 (da) | 1999-01-11 |
| FI952179A7 (fi) | 1995-05-05 |
| US5559269A (en) | 1996-09-24 |
| NO305477B1 (no) | 1999-06-07 |
| AU5438094A (en) | 1994-06-08 |
| DE69317898T2 (de) | 1998-10-15 |
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| UEP | Publication of translation of european patent specification |