NO951775L - Nye 3,3-difenylpropylaminer, deres anvendelse og fremstilling - Google Patents
Nye 3,3-difenylpropylaminer, deres anvendelse og fremstillingInfo
- Publication number
- NO951775L NO951775L NO951775A NO951775A NO951775L NO 951775 L NO951775 L NO 951775L NO 951775 A NO951775 A NO 951775A NO 951775 A NO951775 A NO 951775A NO 951775 L NO951775 L NO 951775L
- Authority
- NO
- Norway
- Prior art keywords
- compounds
- diphenylpropylamines
- methyl
- preparation
- formula
- Prior art date
Links
- KISZTEOELCMZPY-UHFFFAOYSA-N 3,3-diphenylpropylamine Chemical class C=1C=CC=CC=1C(CCN)C1=CC=CC=C1 KISZTEOELCMZPY-UHFFFAOYSA-N 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- -1 methoxy, hydroxy, carbamoyl Chemical group 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001302 tertiary amino group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
- C07C217/62—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
- C07C215/54—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Luminescent Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Photoreceptors In Electrophotography (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9203318A SE9203318D0 (sv) | 1992-11-06 | 1992-11-06 | Novel 3,3-diphenylpropylamines, their use and preparation |
| PCT/SE1993/000927 WO1994011337A1 (en) | 1992-11-06 | 1993-11-05 | Novel 3,3-diphenylpropylamines, their use and preparation |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO951775D0 NO951775D0 (no) | 1995-05-05 |
| NO951775L true NO951775L (no) | 1995-05-05 |
| NO305477B1 NO305477B1 (no) | 1999-06-07 |
Family
ID=20387730
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO951775A NO305477B1 (no) | 1992-11-06 | 1995-05-05 | Nye 3,3-difenylpropylaminer, farmas°ytiske preparater inneholdende slike forbindelser, og deres anvendelse |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | USRE40851E1 (no) |
| EP (1) | EP0667852B1 (no) |
| JP (1) | JP3343256B2 (no) |
| AT (1) | ATE164828T1 (no) |
| AU (1) | AU672458B2 (no) |
| CA (1) | CA2148827C (no) |
| DE (1) | DE69317898T2 (no) |
| DK (1) | DK0667852T3 (no) |
| ES (1) | ES2117155T3 (no) |
| FI (1) | FI120256B (no) |
| HK (1) | HK1006349A1 (no) |
| HU (1) | HU224916B1 (no) |
| NO (1) | NO305477B1 (no) |
| SE (1) | SE9203318D0 (no) |
| WO (1) | WO1994011337A1 (no) |
Families Citing this family (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9203318D0 (sv) | 1992-11-06 | 1992-11-06 | Kabi Pharmacia Ab | Novel 3,3-diphenylpropylamines, their use and preparation |
| WO1998000140A1 (en) * | 1996-07-01 | 1998-01-08 | Sepracor, Inc. | Methods and compositions for treating urinary incontinence using enantiomerically enriched (r)-trihexyphenidyl |
| ATE235903T1 (de) * | 1996-12-02 | 2003-04-15 | Kyorin Seiyaku Kk | Neue derivate von n-substituierten pyrrolidin derivaten und deren herstellungsverfahren |
| SE9701144D0 (sv) | 1997-03-27 | 1997-03-27 | Pharmacia & Upjohn Ab | Novel compounds, their use and preparation |
| EP0957073A1 (en) * | 1998-05-12 | 1999-11-17 | Schwarz Pharma Ag | Novel derivatives of 3,3-diphenylpropylamines |
| SK287111B6 (sk) | 1998-08-27 | 2009-12-07 | Pharmacia & Upjohn Ab | Farmaceutický prípravok obsahujúci tolterodin s regulovaným uvoľňovaním |
| NZ518309A (en) | 1999-11-11 | 2003-05-30 | Pharmacia Ab | Controlled release tolterodine formulation that releases not less than 80% of the active compound in under 18 hours |
| DE29923134U1 (de) * | 1999-11-16 | 2000-06-29 | Schwarz Pharma Ag, 40789 Monheim | Stabile Salze neuartiger Derviate von 3,3-Diphenylpropylaminen |
| SE9904850D0 (sv) * | 1999-12-30 | 1999-12-30 | Pharmacia & Upjohn Ab | Novel process and intermediates |
| US6790854B2 (en) | 2000-03-24 | 2004-09-14 | Meiji Seika Kaisha, Ltd. | Diphenylalkylamine derivatives useful as opioid receptor agonists |
| DE10028443C1 (de) * | 2000-06-14 | 2002-05-29 | Sanol Arznei Schwarz Gmbh | Verfahren zur Herstellung von 3,3-Diarylpropylaminen, (R,S)- und (R)-4-Phenyl-2-chromanon-6-carbonsäure sowie (R)-4-Phenyl-2-chromanon-carbonsäure-cinchonidinsalz und deren Verwendung zur Herstellung eines rechtsdrehenden Hydroxybenzylalkohols und von pharmazeutischen Zusammensetzungen |
| DE10033016A1 (de) * | 2000-07-07 | 2002-01-24 | Sanol Arznei Schwarz Gmbh | Verfahren zur Herstellung von 3,3-Diarylpropylaminen |
| PE20020547A1 (es) | 2000-10-24 | 2002-06-12 | Upjohn Co | Uso de la tolterodina en tratamientos del asma |
| US6951654B2 (en) * | 2001-03-27 | 2005-10-04 | Galen (Chemicals) Limited | Intravaginal drug delivery devices for the administration of an antimicrobial agent |
| US20030027856A1 (en) * | 2001-06-29 | 2003-02-06 | Aberg A.K. Gunnar | Tolterodine metabolites |
| US20030060513A1 (en) * | 2001-09-27 | 2003-03-27 | Arneric Stephen P. | Pharmaceutical composition |
| DE60230546D1 (de) * | 2001-10-26 | 2009-02-05 | Pharmacia & Upjohn Co Llc | Quaternäre ammoniumverbindungen und deren verwendung als antimuscarinische wirkstoffe |
| WO2003039464A2 (en) * | 2001-11-05 | 2003-05-15 | Pharmacia & Upjohn Company | Antimuscarinic aerosol |
| JP2005512995A (ja) * | 2001-11-09 | 2005-05-12 | ファイザー ヘルス アーベー | 不安定又は過活動膀胱を治療するための抗ムスカリン剤及びエストロゲンアゴニスト |
| AU2002360717A1 (en) * | 2001-12-20 | 2003-07-09 | Pharmacia Corporation | Controlled release dosage form having improved drug release properties |
| EP2316468A1 (en) | 2002-02-22 | 2011-05-04 | Shire LLC | Delivery system and methods for protecting and administering dextroamphetamine |
| US7005449B2 (en) * | 2002-04-23 | 2006-02-28 | Pharmacia & Upjohn Company | Tolterodine salts |
| AU2002345266B2 (en) * | 2002-07-08 | 2009-07-02 | Ranbaxy Laboratories Limited | 3,6-disubstituted azabicyclo [3.1.0]hexane derivatives useful as muscarinic receptor antagonists |
| US7825132B2 (en) | 2002-08-23 | 2010-11-02 | Novartis Vaccines And Diagnostics, Inc. | Inhibition of FGFR3 and treatment of multiple myeloma |
| AU2003290699B2 (en) * | 2002-11-13 | 2009-08-27 | Novartis Vaccines And Diagnostics, Inc. | Methods of treating cancer and related methods |
| DE10315917A1 (de) * | 2003-04-08 | 2004-11-18 | Schwarz Pharma Ag | Hochreine Basen von 3,3-Diphenylpropylaminmonoestern |
| WO2004089898A1 (en) * | 2003-04-09 | 2004-10-21 | Ranbaxy Laboratories Limited | Substituted azabicyclo hexane derivatives as muscarinic receptor antagonists |
| EA009387B1 (ru) * | 2003-04-11 | 2007-12-28 | Рэнбакси Лабораториз Лимитед | Азабициклические производные в качестве антагонистов мускаринового рецептора |
| WO2004096751A1 (en) | 2003-04-25 | 2004-11-11 | Pharmacia & Upjohn Company Llc | Halogen substituted 3,3-diphenylpropylamines (tolterodine) having antimuscarinic activity |
| ATE545627T1 (de) * | 2003-05-23 | 2012-03-15 | Bridge Pharma Inc | Glattmuskelspasmolytika |
| WO2005012227A2 (en) * | 2003-08-05 | 2005-02-10 | Ranbaxy Laboratories Limited | Process for preparation of 2-(3-diisopropylamino-1-phenylpropyl)-4-hydroxymethyl-phenol, a metabolite of tolterodine |
| ES2235648B1 (es) * | 2003-12-22 | 2006-11-01 | Ragactives, S.L. | Procedimiento para la obtencion de tolterodina. |
| EP1701932B1 (en) * | 2003-12-24 | 2012-07-18 | Cipla Ltd. | Tolterodine, compositions and uses thereof, and preparation of the same |
| US7875624B2 (en) | 2004-02-20 | 2011-01-25 | Novartis Vaccines And Diagnostics, Inc. | Modulating and measuring cellular adhesion |
| EP1629834A1 (en) | 2004-08-27 | 2006-03-01 | KRKA, D.D., Novo Mesto | Sustained release pharmaceutical composition of tolterodine |
| WO2006064304A1 (en) * | 2004-12-15 | 2006-06-22 | Ranbaxy Laboratories Limited | Acid addition salts of muscarinic receptor antagonists |
| EP1836156A1 (en) * | 2005-01-10 | 2007-09-26 | Teva Gyogyszergyar Reszvenytarsasag | Substantially pure tolterodine tartrate and process for preparing thereof |
| EP1888525A1 (en) * | 2005-05-03 | 2008-02-20 | Ranbaxy Laboratories Limited | 3,6-disubstituted azabicyclo [3.1.0]hexane derivatives as muscarinic receptor antagonists |
| CA2608171C (en) | 2005-05-13 | 2014-02-04 | Novartis Ag | Use of quinolinone compounds for treating drug resistant cancers |
| KR20080076961A (ko) * | 2005-12-20 | 2008-08-20 | 화이자 프로덕츠 인크. | Ｐｄｅ５ 억제제 및 무스카린성 길항제를 포함하는ｌｕｔｓ의 치료를 위한 약제학적 조합물 |
| RS20080411A (sr) | 2006-03-20 | 2009-07-15 | Pfizer Limited, | Derivati amina |
| US8344176B2 (en) | 2006-05-31 | 2013-01-01 | Schwarz Pharma Ltd. | Synthesis of substituted hydroxymethyl phenols |
| EP1862449A1 (en) * | 2006-05-31 | 2007-12-05 | Schwarz Pharma Ltd. | A shortened synthesis of substituted hydroxymethyl phenols |
| IES20060424A2 (en) | 2006-06-08 | 2007-10-31 | Schwarz Pharma Ltd | Accelerated synthesis of (3-Diisopropylamino-1-phenylpropyl)-4-(hydroxymethyl)phenol and its phenolic monoesters |
| ATE477234T1 (de) | 2006-06-09 | 2010-08-15 | Schwarz Pharma Ltd | Synthese von phenolischen estern von hydroxymethylphenolen |
| BRPI0712842A2 (pt) | 2006-06-12 | 2012-07-24 | Sanol Arznei Schwarz Gmbh | internediÁrio quiral, processo para produÇço do mesmo e seu emprego na fabricaÇço da tolterodina, fesoterodina ou o metabàlito ativo das mesmas. |
| IES20060435A2 (en) | 2006-06-12 | 2007-12-12 | Schwarz Pharma Ltd | Shortened synthesis using paraformaldehyde or trioxane |
| EP2044001B1 (en) * | 2006-06-20 | 2016-11-23 | LEK Pharmaceuticals d.d. | Process for preparation of 3-(2-hydroxy-5-substituted phenyl)-n-alkyl-3-phenylpropylamines |
| US20100217034A1 (en) * | 2007-09-21 | 2010-08-26 | Actavis Group Ptc Ehf | Process for the Preparation of Fesoterodine |
| KR101188333B1 (ko) * | 2008-02-20 | 2012-10-09 | 에스케이케미칼주식회사 | 안정성이 우수하고 경피제로 유용한 톨테로딘 결정성산부가염 |
| US20090214665A1 (en) * | 2008-02-26 | 2009-08-27 | Lai Felix S | Controlled Release Muscarinic Receptor Antagonist Formulation |
| WO2010130392A1 (de) * | 2009-05-11 | 2010-11-18 | Ratiopharm Gmbh | Desfesoterodin in form eines weinsäuresalzes |
| IT1394217B1 (it) | 2009-05-15 | 2012-06-01 | Chemi Spa | Metodo di preparazione di fesoterodina e/o fesoterodina fumarato. |
| IT1394219B1 (it) | 2009-05-15 | 2012-06-01 | Chemi Spa | Metodo di preparazione di fesoterodina fumarato di elevata purezza. |
| EP2281801B1 (en) | 2009-07-27 | 2014-01-08 | Crystal Pharma, S.A.U. | Process for obtaining 3,3-diphenylpropylamines |
| IT1396373B1 (it) | 2009-10-29 | 2012-11-19 | Dipharma Francis Srl | Procedimento per la preparazione di fesoterodina. |
| IL210279A0 (en) | 2009-12-25 | 2011-03-31 | Dexcel Pharma Technologies Ltd | Extended release compositions for high solubility, high permeability acdtive pharmaceutical ingredients |
| EP2364966A1 (en) | 2010-03-09 | 2011-09-14 | LEK Pharmaceuticals d.d. | Process for preparation of 3-(2-hydroxy-5-substituted phenyl)-3-phenylpropylamines, intermediates for making hydroxytolterodine |
| WO2011141932A2 (en) | 2010-05-11 | 2011-11-17 | Intas Pharmaceuticals Limited | Process for preparation of phenolic monoesters of hydroxymethyl phenols |
| WO2011145019A1 (en) * | 2010-05-17 | 2011-11-24 | Orchid Chemicals And Pharmaceuticals Limited | Improved process for diphenylpropylamine derivatives |
| IT1401451B1 (it) | 2010-06-10 | 2013-07-26 | Chemi Spa | Nuovo processo di preparazione di 2-idrossi-4-fenil-3,4-diidro-2h-cromen-6-il-metanolo e (r)-2-[3-(diisopropilammino)-1-fenilpropil]-4-(idrossimetil)fenolo. |
| IT1403094B1 (it) | 2010-12-09 | 2013-10-04 | Dipharma Francis Srl | Procedimento per la preparazione di fesoterodina o un suo sale |
| TWI520732B (zh) | 2011-01-18 | 2016-02-11 | 輝瑞有限公司 | 固體分子分散液 |
| US9422228B2 (en) | 2012-05-04 | 2016-08-23 | Crystal Pharma, S.A.U. | Process for the preparation of optically pure fesoterodine derivatives |
| PL2760822T3 (pl) | 2012-06-14 | 2016-09-30 | Sole desfezoterodyny | |
| ITMI20121232A1 (it) | 2012-07-16 | 2014-01-17 | Cambrex Profarmaco Milano Srl | Procedimento per la preparazione di 2-(3-n,n-diisopropilamino-1-fenilpropil)-4-idrossimetil-fenolo e suoi derivati |
| GB201402556D0 (en) | 2014-02-13 | 2014-04-02 | Crystec Ltd | Improvements relating to inhalable particles |
| WO2016148444A1 (ko) * | 2015-03-17 | 2016-09-22 | 제이더블유중외제약 주식회사 | 신규 데스페소테로딘 유도체, 이의 약제학적으로 허용되는 염 및 이를 포함하는 약제학적 조성물 |
| WO2017137955A1 (en) | 2016-02-14 | 2017-08-17 | Celestis Pharmaceuticals Pvt. Ltd. | Novel (r) and rac 3-(2-(allyloxy)-5-methylphenyl)-n,n-diisopropyl-3- phenylpropan-1-amine and its use for synthesis of (r) and rac-2-(3- (diisopropylamino)-1-phenylpropyl)-4-(hydroxymethyl)phenol |
| CN110372571B (zh) * | 2018-04-12 | 2022-11-15 | 中国科学院大连化学物理研究所 | 一种2-(2,2-二芳基乙基)-环胺衍生物或盐及合成和应用与组合物 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK111894A (no) | 1962-11-15 | |||
| GB1169945A (en) | 1966-08-25 | 1969-11-05 | Geistlich Soehne Ag | Pharmaceutical Compositions containing Diphenylalkyl-amine Derivatives |
| GB1169944A (en) | 1966-08-25 | 1969-11-05 | Geistlich Soehne Ag | Novel 3,3-Diphenylpropylamines and processes for the preparation thereof |
| US4139537A (en) | 1976-06-29 | 1979-02-13 | Cooper Laboratories, Inc. | 3-Aryloxy-1-(2- or 4-iminodihydro-1-pyridyl)-2-propanol antiarrhythmic compounds |
| US5382600A (en) * | 1988-01-22 | 1995-01-17 | Pharmacia Aktiebolag | 3,3-diphenylpropylamines and pharmaceutical compositions thereof |
| SE8800207D0 (sv) | 1988-01-22 | 1988-01-22 | Kabivitrum Ab | Nya aminer, deras anvendning och framstellning |
| SE9203318D0 (sv) | 1992-11-06 | 1992-11-06 | Kabi Pharmacia Ab | Novel 3,3-diphenylpropylamines, their use and preparation |
| US5472958A (en) * | 1994-08-29 | 1995-12-05 | Abbott Laboratories | 2-((nitro)phenoxymethyl) heterocyclic compounds that enhance cognitive function |
| PE20020547A1 (es) * | 2000-10-24 | 2002-06-12 | Upjohn Co | Uso de la tolterodina en tratamientos del asma |
-
1992
- 1992-11-06 SE SE9203318A patent/SE9203318D0/xx unknown
-
1993
- 1993-11-05 WO PCT/SE1993/000927 patent/WO1994011337A1/en not_active Ceased
- 1993-11-05 ES ES93924876T patent/ES2117155T3/es not_active Expired - Lifetime
- 1993-11-05 JP JP51197794A patent/JP3343256B2/ja not_active Expired - Lifetime
- 1993-11-05 AU AU54380/94A patent/AU672458B2/en not_active Expired
- 1993-11-05 DK DK93924876T patent/DK0667852T3/da active
- 1993-11-05 US US11/402,337 patent/USRE40851E1/en not_active Expired - Lifetime
- 1993-11-05 DE DE69317898T patent/DE69317898T2/de not_active Expired - Lifetime
- 1993-11-05 EP EP93924876A patent/EP0667852B1/en not_active Expired - Lifetime
- 1993-11-05 CA CA002148827A patent/CA2148827C/en not_active Expired - Lifetime
- 1993-11-05 HK HK98105466A patent/HK1006349A1/en not_active IP Right Cessation
- 1993-11-05 US US11/017,635 patent/USRE39667E1/en not_active Expired - Lifetime
- 1993-11-05 AT AT93924876T patent/ATE164828T1/de active
- 1993-11-05 HU HU9501329A patent/HU224916B1/hu unknown
-
1995
- 1995-05-05 FI FI952179A patent/FI120256B/fi not_active IP Right Cessation
- 1995-05-05 US US08/432,113 patent/US5559269A/en not_active Ceased
- 1995-05-05 NO NO951775A patent/NO305477B1/no not_active IP Right Cessation
-
1996
- 1996-07-22 US US08/684,638 patent/US5686464A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| FI952179A7 (fi) | 1995-05-05 |
| CA2148827C (en) | 2005-01-04 |
| ES2117155T3 (es) | 1998-08-01 |
| NO305477B1 (no) | 1999-06-07 |
| JPH08503208A (ja) | 1996-04-09 |
| FI952179A0 (fi) | 1995-05-05 |
| DE69317898D1 (de) | 1998-05-14 |
| DE69317898T2 (de) | 1998-10-15 |
| HK1006349A1 (en) | 1999-02-19 |
| FI120256B (fi) | 2009-08-31 |
| DK0667852T3 (da) | 1999-01-11 |
| CA2148827A1 (en) | 1994-05-26 |
| HU224916B1 (en) | 2006-04-28 |
| HUT72742A (en) | 1996-05-28 |
| NO951775D0 (no) | 1995-05-05 |
| AU5438094A (en) | 1994-06-08 |
| WO1994011337A1 (en) | 1994-05-26 |
| HU9501329D0 (en) | 1995-06-28 |
| US5559269A (en) | 1996-09-24 |
| ATE164828T1 (de) | 1998-04-15 |
| USRE40851E1 (en) | 2009-07-14 |
| JP3343256B2 (ja) | 2002-11-11 |
| USRE39667E1 (en) | 2007-05-29 |
| EP0667852A1 (en) | 1995-08-23 |
| US5686464A (en) | 1997-11-11 |
| SE9203318D0 (sv) | 1992-11-06 |
| EP0667852B1 (en) | 1998-04-08 |
| AU672458B2 (en) | 1996-10-03 |
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