ATE165241T1 - Zubereitung enthaltend l-carnitin oder acyl-l- carnitin in kombination mit einem ace-inhibitor zur behandlung von kardiovaskulären störungen - Google Patents

Zubereitung enthaltend l-carnitin oder acyl-l- carnitin in kombination mit einem ace-inhibitor zur behandlung von kardiovaskulären störungen

Info

Publication number: ATE165241T1
Authority: AT; Austria
Prior art keywords: carnitine; acyl; combination; cardiovascular disorders; treatment
Prior art date: 1992-03-27

Application number

AT93830120T

Other languages

English (en)

Inventor

Claudio Cavazza

Original Assignee

Sigma Tau Ind Farmaceuti

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-03-27

Filing date

1993-03-26

Publication date

1998-05-15

1993-03-26 Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti

1998-05-15 Application granted granted Critical

1998-05-15 Publication of ATE165241T1 publication Critical patent/ATE165241T1/de

Links

PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 title abstract 3
239000005541 ACE inhibitor Substances 0.000 title abstract 3
229940044094 angiotensin-converting-enzyme inhibitor Drugs 0.000 title abstract 3
208000024172 Cardiovascular disease Diseases 0.000 title abstract 2
-1 acyl L-carnitine Chemical compound 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
108010007859 Lisinopril Proteins 0.000 abstract 1
239000002552 dosage form Substances 0.000 abstract 1
RLAWWYSOJDYHDC-BZSNNMDCSA-N lisinopril Chemical compound C([C@H](N[C@@H](CCCCN)C(=O)N1[C@@H](CCC1)C(O)=O)C(O)=O)CC1=CC=CC=C1 RLAWWYSOJDYHDC-BZSNNMDCSA-N 0.000 abstract 1
229960002394 lisinopril Drugs 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/556—Angiotensin converting enzyme inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Cardiology (AREA)
Organic Chemistry (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT93830120T 1992-03-27 1993-03-26 Zubereitung enthaltend l-carnitin oder acyl-l- carnitin in kombination mit einem ace-inhibitor zur behandlung von kardiovaskulären störungen ATE165241T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
ITRM920222A IT1254314B (it)	1992-03-27	1992-03-27	Composizioni farmaceutiche conyenenti l-carnitina e acil- carnitine inassociazione con ace-inibitori per il trattamento di patologie cardiovascolari.

Publications (1)

Publication Number	Publication Date
ATE165241T1 true ATE165241T1 (de)	1998-05-15

Family

ID=11400880

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT93830120T ATE165241T1 (de)	1992-03-27	1993-03-26	Zubereitung enthaltend l-carnitin oder acyl-l- carnitin in kombination mit einem ace-inhibitor zur behandlung von kardiovaskulären störungen

Country Status (11)

Country	Link
US (1)	US5861434A (de)
EP (1)	EP0566542B1 (de)
JP (1)	JP3616116B2 (de)
KR (1)	KR100244092B1 (de)
AT (1)	ATE165241T1 (de)
CA (1)	CA2092505C (de)
DE (1)	DE69318061T2 (de)
DK (1)	DK0566542T3 (de)
ES (1)	ES2116429T3 (de)
HK (1)	HK1009325A1 (de)
IT (1)	IT1254314B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2733911B1 (fr) *	1995-05-09	1998-05-29	Takeda Chemical Industries Ltd	Composition pharmaceutique pour maladies renales ou cardio-vasculaires
IT1277953B1 (it) *	1995-12-21	1997-11-12	Sigma Tau Ind Farmaceuti	Composizione farmaceutica contenente l-carnitina o una alcanoil l- carnitina e un acido poliinsaturo della serie 3-omega utile per
IT1284661B1 (it) *	1996-06-06	1998-05-21	Sigma Tau Ind Farmaceuti	Uso di alcanoil l-carnitine nel trattamento terapeutico di malattie infiammatorie croniche intestinali.
DK0951909T4 (da)	1998-03-19	2011-01-24	Sigma Tau Ind Farmaceuti	Kombinationspræparat omfattende en L-carnitin eller en alkanoyl-L-carnitin, en glycosaminoglycan og/eller bestanddel deraf
LV12491B (lv) *	1998-10-29	2000-12-20	Ivars KALVI��	Farmaceitiska kompozīcija
CA2350071A1 (en) *	1998-11-11	2000-05-18	Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.	Use of propionyl l-carnitine for the preparation of a medicament capable of inducing apoptosis
US20030206895A1 (en) *	1998-11-13	2003-11-06	Sigma-Tau Healthscience S.P.A.	Antioxidant composition comprising propionyl L-carnitine and a flavonoid against throm-bosis and atherosclerosis
IT1306722B1 (it) *	1999-10-08	2001-10-02	Sigma Tau Healthscience Spa	Composizione per la prevenzione e/o il trattamento di disfunzionicircolatorie, comprendente derivati della l-carnitina ed estratti di
JP2003521496A (ja) *	2000-01-26	2003-07-15	ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー	Ａｃｅ阻害剤−バソプレッシンアンタゴニストの組み合わせ
GB0624084D0 (en) *	2006-12-01	2007-01-10	Selamine Ltd	Ramipril amino acid salts
AU2008228192B2 (en) *	2007-03-21	2013-02-07	Alfasigma S.p.A	Composition useful for the prevention of type 2 diabetes and its complications in pre-diabetic patients with insulin resistance
WO2010096582A2 (en) *	2009-02-18	2010-08-26	Rayspan Corporation	Metamaterial power amplifier systems

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU518617B2 (en) *	1977-04-29	1981-10-08	Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.	Therapeutic application of acetyl-d, 1-carnitine
CH655005A5 (it) *	1983-02-16	1986-03-27	Sigma Tau Ind Farmaceuti	Composizione farmaceutica ad azione metabolica ed energetica utilizzabile in terapia cardiaca e vascolare.
US5025001A (en) *	1988-06-15	1991-06-18	Brigham And Women's Hospital	S-nitroso derivatives of ACE inhibitors and the use thereof
IT1235153B (it) *	1988-11-15	1992-06-22	Sigma Tau Ind Farmaceuti	Uso dell'acetil l-carnitina nel trattamento terapeutico della cataratta e composizioni farmaceutiche utili in tale trattamento
IT1224795B (it) *	1988-12-01	1990-10-24	Sigma Tau Ind Farmaceuti	Uso dell'acetil d-carnitina nel trattamento terapeutico del glaucoma e composizioni farmaceutiche utili in tale trattamento
IT1224842B (it) *	1988-12-27	1990-10-24	Sigma Tau Ind Farmaceuti	Uso di derivati della l-carnitina nel trattamento terapeutico delle alterazioni degenerative del sistema nervoso
IT1240799B (it) *	1990-03-15	1993-12-17	Sigma Tau Ind Farmaceuti	Composizioni farmaceutiche contenenti 3-metiltiopropionil l-carnitina ad attivita' sul sistema cardiovascolare.
IT1244636B (it) *	1991-01-04	1994-08-08	Sigma Tau Ind Farmaceuti	Uso dell'acetil l-carnitina nel trattamento terapeutico del coma e composizioni farmaceutiche utili in tale trattamento.
IT1248323B (it) *	1991-05-16	1995-01-05	Sigma Tau Ind Farmaceuti	Ammidi con amminoacidi naturali di alcanoil l-carnitine quali inibitori della degenerazione neuronale e attivatori dei processi di apprendimento e memorizzazione e per il trattamento del coma e composizioni farmaceutiche comprendenti tali composti
IT1245699B (it) *	1991-05-29	1994-10-14	Sigma Tau Ind Farmaceuti	Derivati della l-carnitina quali agenti terapeutici per il trattamento delle miopatie, della degenarazione neuronale e per inibire la proteolisi

1992
- 1992-03-27 IT ITRM920222A patent/IT1254314B/it active
1993
- 1993-03-25 CA CA002092505A patent/CA2092505C/en not_active Expired - Lifetime
- 1993-03-26 AT AT93830120T patent/ATE165241T1/de active
- 1993-03-26 ES ES93830120T patent/ES2116429T3/es not_active Expired - Lifetime
- 1993-03-26 EP EP93830120A patent/EP0566542B1/de not_active Expired - Lifetime
- 1993-03-26 DK DK93830120T patent/DK0566542T3/da active
- 1993-03-26 JP JP06797193A patent/JP3616116B2/ja not_active Expired - Lifetime
- 1993-03-26 DE DE69318061T patent/DE69318061T2/de not_active Expired - Lifetime
- 1993-03-27 KR KR1019930004877A patent/KR100244092B1/ko not_active Expired - Lifetime
1996
- 1996-03-08 US US08/612,671 patent/US5861434A/en not_active Expired - Lifetime
1998
- 1998-08-15 HK HK98109954A patent/HK1009325A1/en unknown

Also Published As

Publication number	Publication date
ITRM920222A0 (it)	1992-03-27
ITRM920222A1 (it)	1993-09-27
CA2092505A1 (en)	1993-09-28
KR100244092B1 (ko)	2000-03-02
ES2116429T3 (es)	1998-07-16
HK1009325A1 (en)	1999-05-28
DK0566542T3 (da)	1999-01-04
US5861434A (en)	1999-01-19
EP0566542B1 (de)	1998-04-22
DE69318061D1 (de)	1998-05-28
EP0566542A1 (de)	1993-10-20
KR930019208A (ko)	1993-10-18
JP3616116B2 (ja)	2005-02-02
IT1254314B (it)	1995-09-14
JPH0616570A (ja)	1994-01-25
DE69318061T2 (de)	1998-08-13
CA2092505C (en)	2004-06-01

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Legal Events

Date	Code	Title	Description
1998-11-15	UEP	Publication of translation of european patent specification