ATE165357T1 - Neue verwendung bis-heterocyclische verbindungen und dessen zusammensetzungen - Google Patents

Neue verwendung bis-heterocyclische verbindungen und dessen zusammensetzungen

Info

Publication number
ATE165357T1
ATE165357T1 AT94909794T AT94909794T ATE165357T1 AT E165357 T1 ATE165357 T1 AT E165357T1 AT 94909794 T AT94909794 T AT 94909794T AT 94909794 T AT94909794 T AT 94909794T AT E165357 T1 ATE165357 T1 AT E165357T1
Authority
AT
Austria
Prior art keywords
compounds
compositions
heterocyclic compounds
new use
bis
Prior art date
Application number
AT94909794T
Other languages
English (en)
Inventor
Oliver J Mcconnell
Gabriel Saucy
Robert Jacobs
Original Assignee
Harbor Branch Oceanographic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harbor Branch Oceanographic filed Critical Harbor Branch Oceanographic
Application granted granted Critical
Publication of ATE165357T1 publication Critical patent/ATE165357T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Characterised By The Charging Evacuation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT94909794T 1993-02-24 1994-02-24 Neue verwendung bis-heterocyclische verbindungen und dessen zusammensetzungen ATE165357T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/021,929 US5290777A (en) 1993-02-24 1993-02-24 Use for topsentin compounds and pharmaceutical compositions containing same

Publications (1)

Publication Number Publication Date
ATE165357T1 true ATE165357T1 (de) 1998-05-15

Family

ID=21806918

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94909794T ATE165357T1 (de) 1993-02-24 1994-02-24 Neue verwendung bis-heterocyclische verbindungen und dessen zusammensetzungen

Country Status (8)

Country Link
US (3) US5290777A (de)
EP (1) EP0686154B1 (de)
JP (1) JP4028888B2 (de)
AT (1) ATE165357T1 (de)
CA (1) CA2155323C (de)
DE (1) DE69409796T2 (de)
ES (1) ES2115220T3 (de)
WO (1) WO1994019343A2 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639468A (en) * 1995-06-07 1997-06-17 University Of Southern California Method for reducing or preventing post-surgical adhesion formation using manoalide and analogs thereof
US5977117A (en) * 1996-01-05 1999-11-02 Texas Biotechnology Corporation Substituted phenyl compounds and derivatives thereof that modulate the activity of endothelin
JP2001503414A (ja) * 1996-10-31 2001-03-13 ハーバー ブランチ オーシャノグラフィック インスティテューション インク． 抗神経性炎症化合物および組成物ならびにその使用法
WO1999042092A2 (en) * 1998-02-20 1999-08-26 Harbor Branch Oceanographic Institution, Inc. Compounds and methods of use for treatment of neurogenic inflammation
US6589975B2 (en) 1998-07-08 2003-07-08 The Regents Of The University Of California Synthetic compounds for treatment of inflammation
JP2002520315A (ja) 1998-07-08 2002-07-09 ハーバー ブランチ オーシャノグラフィック インスティテューション インク． ビスインドール誘導体および抗炎症剤としてのそれらの使用
US6492406B1 (en) 1999-05-21 2002-12-10 Astrazeneca Ab Pharmaceutically active compounds
US6087363A (en) * 1999-07-16 2000-07-11 Harbor Branch Oceanographic Institution, Inc. Use of imidazole and indole compounds as inhibitors of nitric oxide synthase
KR100404580B1 (ko) * 2000-04-20 2003-11-05 한국해양연구원 원도닌 ａ 및 그의 제조방법
WO2003022274A2 (en) * 2001-09-13 2003-03-20 Synta Pharmaceuticals Corp. 2-aroylimidazole compounds for treating cancer
US7573159B1 (en) 2001-10-22 2009-08-11 Apple Inc. Power adapters for powering and/or charging peripheral devices
WO2016023106A1 (en) * 2014-08-15 2016-02-18 The University Of British Columbia Bis-indole alkaloids for use in the treatment of infections
CN107814790B (zh) * 2016-09-12 2021-03-30 南开大学 Topsentin类衍生物及其制备和在抗植物病毒和病菌中的应用
CN107810961B (zh) * 2016-09-12 2021-04-02 南开大学 Topsentin类生物碱在抗植物病毒和病菌中的应用
CN109418267B (zh) * 2017-08-21 2021-03-30 南开大学 Nortopsentin类生物碱及其衍生物在防治植物病虫害中的应用
CN109422734B (zh) * 2017-08-21 2021-03-30 南开大学 Nortopsentin类生物碱衍生物及其制备和在防治病虫害中的应用
CN121135694A (zh) * 2025-09-22 2025-12-16 湖南中医药大学 一种双吲哚生物碱(S)-6’’-Debromohamacanthin A的不对称制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0272810A3 (de) * 1986-11-26 1988-07-20 Harbor Branch Oceanographic Institution, Inc. Antitumor- und Antiviral-Alkaloide
US4895844A (en) * 1987-03-25 1990-01-23 Harbor Branch Oceanographic Institution, Inc. Indole alkaloid compositions and their methods of use
US4866084A (en) * 1987-07-17 1989-09-12 Harbor Branch Oceanographic Institution, Inc. Topsentin compounds effective against viruses and certain tumors
CZ280738B6 (cs) * 1988-02-10 1996-04-17 F. Hoffmann - La Roche And Co., Aktiengesellschaft Substituované pyrroly, jejich použití pro výrobu léčiv a léčiva na jejich bázi
US4970226A (en) * 1989-10-03 1990-11-13 Harbor Branch Oceanographic Institution, Inc. Bis-indole imidazole compounds which are useful antitumor and antimicrobial agents

Also Published As

Publication number Publication date
JPH09500091A (ja) 1997-01-07
EP0686154A1 (de) 1995-12-13
US5290777A (en) 1994-03-01
CA2155323A1 (en) 1994-09-01
DE69409796D1 (de) 1998-05-28
JP4028888B2 (ja) 2007-12-26
WO1994019343A2 (en) 1994-09-01
US5496950A (en) 1996-03-05
WO1994019343A3 (en) 1994-10-27
DE69409796T2 (de) 1998-08-13
US5464835A (en) 1995-11-07
ES2115220T3 (es) 1998-06-16
CA2155323C (en) 2005-06-14
EP0686154B1 (de) 1998-04-22

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties