ATE165514T1 - Verwendung von inosittriphosphat zur zubereitung von medikamenten - Google Patents

Verwendung von inosittriphosphat zur zubereitung von medikamenten

Info

Publication number: ATE165514T1
Authority: AT; Austria
Prior art keywords: inosite; triphosphate; preparing; preparing medications; medications
Prior art date: 1990-06-28

Application number

AT91912558T

Other languages

English (en)

Inventor

Matti Siren

Lars Edvinsson

Original Assignee

Perstorp Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-06-28

Filing date

1991-06-19

Publication date

1998-05-15

1991-06-19 Application filed by Perstorp Ab filed Critical Perstorp Ab

1998-05-15 Application granted granted Critical

1998-05-15 Publication of ATE165514T1 publication Critical patent/ATE165514T1/de

Links

239000003814 drug Substances 0.000 title abstract 2
229940079593 drug Drugs 0.000 title 1
CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 title 1
CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 title 1
235000011178 triphosphate Nutrition 0.000 title 1
239000001226 triphosphate Substances 0.000 title 1
UNXRWKVEANCORM-UHFFFAOYSA-N triphosphoric acid Chemical compound OP(O)(=O)OP(O)(=O)OP(O)(O)=O UNXRWKVEANCORM-UHFFFAOYSA-N 0.000 title 1
MMWCIQZXVOZEGG-UHFFFAOYSA-N 1,4,5-IP3 Natural products OC1C(O)C(OP(O)(O)=O)C(OP(O)(O)=O)C(O)C1OP(O)(O)=O MMWCIQZXVOZEGG-UHFFFAOYSA-N 0.000 abstract 3
MMWCIQZXVOZEGG-XJTPDSDZSA-N D-myo-Inositol 1,4,5-trisphosphate Chemical compound O[C@@H]1[C@H](O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H](O)[C@@H]1OP(O)(O)=O MMWCIQZXVOZEGG-XJTPDSDZSA-N 0.000 abstract 3
239000005557 antagonist Substances 0.000 abstract 1
230000002490 cerebral effect Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000002526 effect on cardiovascular system Effects 0.000 abstract 1
BPGXUIVWLQTVLZ-OFGSCBOVSA-N neuropeptide y(npy) Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(O)=O)NC(=O)[C@H](CC=1N=CNC=1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H]1N(CCC1)C(=O)[C@@H](N)CC=1C=CC(O)=CC=1)C1=CC=C(O)C=C1 BPGXUIVWLQTVLZ-OFGSCBOVSA-N 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Epidemiology (AREA)
Hematology (AREA)
Obesity (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Diabetes (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT91912558T 1990-06-28 1991-06-19 Verwendung von inosittriphosphat zur zubereitung von medikamenten ATE165514T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE9002278A SE9002278L (sv)	1990-06-28	1990-06-28	Anvaendning av inositoltrisfosfat foer framstaellning av ett laekemedel

Publications (1)

Publication Number	Publication Date
ATE165514T1 true ATE165514T1 (de)	1998-05-15

Family

ID=20379887

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT91912558T ATE165514T1 (de)	1990-06-28	1991-06-19	Verwendung von inosittriphosphat zur zubereitung von medikamenten

Country Status (10)

Country	Link
US (1)	US5284839A (de)
EP (2)	EP0554861A1 (de)
JP (1)	JPH0639383B2 (de)
AT (1)	ATE165514T1 (de)
AU (1)	AU8188691A (de)
DE (1)	DE69129331T2 (de)
DK (1)	DK0536269T3 (de)
ES (1)	ES2115616T3 (de)
SE (1)	SE9002278L (de)
WO (1)	WO1992000079A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9213215D0 (en) *	1992-06-20	1992-08-05	Wellcome Found	Peptides
IT1265647B1 (it) *	1992-11-18	1996-11-22	Farmin Srl	Composizione farmaceutiche topiche per le allergie respiratorie
WO1995005830A1 (en) *	1993-08-20	1995-03-02	The Regents Of The University Of California	Polyanion anti-inflammatory agents
US5516653A (en) *	1993-12-28	1996-05-14	Synaptic Pharmaceutical Corporation	DNA encoding a human neuropeptide Y/peptide YY/pancreatic polypeptide receptor (Y4) and uses thereof
US5545549A (en) *	1994-02-03	1996-08-13	Synaptic Pharmaceutical Corporation	DNA encoding a human neuropeptide Y/peptide YY (Y2) receptor and uses thereof
US5602024A (en)	1994-12-02	1997-02-11	Synaptic Pharmaceutical Corporation	DNA encoding a hypothalamic atypical neuropeptide Y/peptide YY receptor (Y5) and uses thereof
US5989920A (en) *	1994-12-02	1999-11-23	Synaptic Pharmaceutical Corporation	Methods of modifying feeding behavior compounds useful in such methods and DNA encoding a hypothalmic atypical neuropeptide Y/peptide YY receptor Y5
US7048906B2 (en)	1995-05-17	2006-05-23	Cedars-Sinai Medical Center	Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions
FR2754709B1 (fr)	1996-10-23	1999-03-05	Sanofi Sa	Composition cosmetique contenant un antagoniste des recepteurs du neuropeptide gamma et alpha 2 antagonistes susceptibles d'etre incorpores dans une telle composition
US6713265B1 (en)	1997-06-04	2004-03-30	Synaptic Pharmaceutical Corporation	Methods of modifying feeding behavior, compounds useful in such methods, and DNA encoding a hypothalamic atypical neuropeptide Y/peptide YY receptor (Y5)
CN1135983C (zh) *	2001-06-28	2004-01-28	中山大学	二酸（5－雄甾烯－17－酮－3β－羟基）二酯用于制备药物
GB0121709D0 (en) *	2001-09-07	2001-10-31	Imp College Innovations Ltd	Food inhibition agent
EP1585956A4 (de) *	2001-09-24	2009-10-21	Univ Oregon Health & Science	Beurteilung von neuronen im nucleus arcuatus zum screening auf das essverhalten verändernde stoffe
ES2320979T3 (es)	2001-09-24	2009-06-01	Imperial Innovations Limited	Pyy-36 para la reduccion o prevencion de la obesidad.
JP4733922B2 (ja)	2002-01-10	2011-07-27	インペリアル・イノベ−ションズ・リミテッド	摂食行動の修正
US8058233B2 (en) *	2002-01-10	2011-11-15	Oregon Health And Science University	Modification of feeding behavior using PYY and GLP-1
KR20040051455A (ko) *	2002-12-12	2004-06-18	아미코젠주식회사	산화적 손상을 예방하기 위한 카이로이노시톨 또는피니톨의 용도 및 이들을 함유하는 당뇨합병증 예방용조성물
GB0300571D0 (en) *	2003-01-10	2003-02-12	Imp College Innovations Ltd	Modification of feeding behaviour
GB0511986D0 (en) *	2005-06-13	2005-07-20	Imp College Innovations Ltd	Novel compounds and their effects on feeding behaviour
TWI428346B (zh) *	2006-12-13	2014-03-01	Imp Innovations Ltd	新穎化合物及其等對進食行為影響
WO2011005886A1 (en) *	2009-07-07	2011-01-13	Normoxys, Inc.	Method of reducing multi-drug resistance using inositol tripyrophosphate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE465951B (sv) *	1984-10-23	1991-11-25	Perstorp Ab	Isomer av inositoltrifosfat foeretraedesvis i saltform foer anvaendning som terapeutiskt eller profylaktiskt medel samt kompositioner daerav
SE465305B (sv) *	1986-04-16	1991-08-26	Perstorp Ab	Anvaendning av inositolfosfat foer framstaellning av ett laekemedel
SE464059C (sv) *	1988-09-15	1997-06-02	Perstorp Ab	Användning av inositoltrifosfat för framställning av läkemedel

1990
- 1990-06-28 SE SE9002278A patent/SE9002278L/ not_active Application Discontinuation
1991
- 1991-06-19 AT AT91912558T patent/ATE165514T1/de not_active IP Right Cessation
- 1991-06-19 AU AU81886/91A patent/AU8188691A/en not_active Abandoned
- 1991-06-19 DK DK91912558T patent/DK0536269T3/da active
- 1991-06-19 EP EP93101712A patent/EP0554861A1/de not_active Withdrawn
- 1991-06-19 WO PCT/SE1991/000439 patent/WO1992000079A1/en not_active Ceased
- 1991-06-19 US US07/966,035 patent/US5284839A/en not_active Expired - Fee Related
- 1991-06-19 EP EP91912558A patent/EP0536269B1/de not_active Expired - Lifetime
- 1991-06-19 DE DE69129331T patent/DE69129331T2/de not_active Expired - Fee Related
- 1991-06-19 ES ES91912558T patent/ES2115616T3/es not_active Expired - Lifetime
- 1991-06-27 JP JP3156823A patent/JPH0639383B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
WO1992000079A1 (en)	1992-01-09
ES2115616T3 (es)	1998-07-01
AU8188691A (en)	1992-01-23
DE69129331T2 (de)	1998-09-24
JPH04230220A (ja)	1992-08-19
DK0536269T3 (da)	1998-10-07
SE9002278D0 (sv)	1990-06-28
EP0536269A1 (de)	1993-04-14
JPH0639383B2 (ja)	1994-05-25
DE69129331D1 (de)	1998-06-04
SE9002278L (sv)	1991-12-29
EP0554861A1 (de)	1993-08-11
US5284839A (en)	1994-02-08
EP0536269B1 (de)	1998-04-29

Legal Events

Date	Code	Title	Description
1999-01-15	UEP	Publication of translation of european patent specification
2002-03-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE69129331D1 (de)	1998-06-04	Verwendung von inosittriphosphat zur zubereitung von medikamenten
DE69232323D1 (de)	2002-02-07	Verwendung von Adenosinantagonisten zur Vorbeugung und Behandlung von Pankreatitis und Ulcera
DE69109021D1 (de)	1995-05-24	Augentropfenarzneimittel.
PT97638A (pt)	1992-02-28	Processo para a preparacao de compostos peptidicos e de composicoes farmaceuticas que os contem
ATE108657T1 (de)	1994-08-15	Galanthemin enthaltende pharmazeutische formulierung zur behandlung des alkoholismus.
ATE148630T1 (de)	1997-02-15	Stabilisierte derivate von vitamin d2 und d3 enthaltende pharmazeutische zusammensetzungen
FI870457A0 (fi)	1987-02-03	Farmaceutiska preparatformer foer stabilisering av interferon- .
ATE224728T1 (de)	2002-10-15	Arzneimittel enthaltend aktiviertes protein c
RU94031161A (ru)	1996-03-27	Фармацевтическая композиция и способ ее получения, способ лечения нарушений, развивающихся вследствие нейродегенеративных процессов
DE59200277D1 (de)	1994-08-18	Substituierte Diaminophthalimide und Analoga.
ATE101594T1 (de)	1994-03-15	Einen zink-komplex enthaltende arzneimittel.
DK0636027T3 (da)	2000-01-31	Angiotensin-II-antogonister mod sygdomme forbundet med forringet neuronal ledningshastighed, især diabetisk neuropati
DE69029693D1 (de)	1997-02-27	Hydantoin- oder Imidazolidintrionderivate zur Vorbeugung oder Behandlung von Niereninsuffizienz
DE69114635D1 (de)	1995-12-21	1,3-Diphenyl-2-propin-1-one.
NO882559L (no)	1988-12-13	Transdermalt leveringssystem for farmasoeytiske forbindelser.
DK0524696T3 (da)	1996-08-12	Orale præparater indeholdende dapiprazol
ATE76754T1 (de)	1992-06-15	Pharmazeutische zusammensetzung zur milderung der nebenwirkungen von platinhaltigen arzneimitteln.
ATE224716T1 (de)	2002-10-15	Pharmazeutische zusammensetzungen von cinchonin dihydrochlorid
KR920700641A (ko)	1992-08-10	클로르메티아졸의 신경 변성 예방 및(또는) 치료용 용도
DK1100463T3 (da)	2003-01-20	Injicerbare formuleringer indeholdende ramoplanin
ATE87482T1 (de)	1993-04-15	Pharmazeutische praeparate zur behandlung von zereberalen psycho-organischen syndromen.
ITMI911845A1 (it)	1993-01-04	Uso dei derivati dell'acido benzimidazolin-2-oxo-1-carbossilico.
DE69107226D1 (de)	1995-03-23	Verwendung von Tumornekrosefaktor.
ES2101982T3 (es)	1997-07-16	Composicion conteniendo una alta dosis de vitamina a.
IT9019002A1 (it)	1991-07-03	Composti otticamente attivi per la profilassi dell'insufficienza coronarica acuta e cronica, loro preparazione e composizioni farmaceutiche che li contengono