ATE165983T1 - Reduktion von hautirritationen und hautwiderstand während einer iontophoresebehandlung - Google Patents

Reduktion von hautirritationen und hautwiderstand während einer iontophoresebehandlung

Info

Publication number
ATE165983T1
ATE165983T1 AT94929146T AT94929146T ATE165983T1 AT E165983 T1 ATE165983 T1 AT E165983T1 AT 94929146 T AT94929146 T AT 94929146T AT 94929146 T AT94929146 T AT 94929146T AT E165983 T1 ATE165983 T1 AT E165983T1
Authority
AT
Austria
Prior art keywords
skin
reduction
resistance during
potassium
irritations
Prior art date
Application number
AT94929146T
Other languages
English (en)
Inventor
Michael J N Cormier
Philip W Ledger
Juanita Johnson
Joseph B Phipps
Stella Chao
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of ATE165983T1 publication Critical patent/ATE165983T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Electrotherapy Devices (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Electric Double-Layer Capacitors Or The Like (AREA)
  • Control Of Non-Electrical Variables (AREA)
AT94929146T 1993-09-03 1994-08-31 Reduktion von hautirritationen und hautwiderstand während einer iontophoresebehandlung ATE165983T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/116,660 US5533971A (en) 1993-09-03 1993-09-03 Reduction of skin irritation during electrotransport

Publications (1)

Publication Number Publication Date
ATE165983T1 true ATE165983T1 (de) 1998-05-15

Family

ID=22368498

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94929146T ATE165983T1 (de) 1993-09-03 1994-08-31 Reduktion von hautirritationen und hautwiderstand während einer iontophoresebehandlung

Country Status (11)

Country Link
US (1) US5533971A (de)
EP (1) EP0717645B1 (de)
JP (1) JP3664726B2 (de)
AT (1) ATE165983T1 (de)
AU (1) AU681447B2 (de)
CA (1) CA2166490C (de)
DE (1) DE69410279T2 (de)
DK (1) DK0717645T3 (de)
ES (1) ES2116618T3 (de)
NZ (1) NZ274317A (de)
WO (1) WO1995006497A1 (de)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050159698A1 (en) * 1993-09-30 2005-07-21 Vyteris, Inc. Iontophoretic drug delivery device and reservoir and method of making same
KR970701074A (ko) * 1994-02-15 1997-03-17 프란세스코 마체타 카테테르 관련 감염 발병을 방지하는 람모플라닌족 항생제가 적재된 중심 정맥 카테테르(Central Venous Catheters Loaded With Antibiotics of the Ramoplanin Group Preventing Development of catheter Related Infections)
US5990179A (en) * 1995-04-28 1999-11-23 Alza Corporation Composition and method of enhancing electrotransport agent delivery
IE960312A1 (en) 1995-06-02 1996-12-11 Alza Corp An electrotransport delivery device with voltage boosting¹circuit
WO1997004835A1 (de) * 1995-07-28 1997-02-13 Novartis Ag Transdermales system
WO1997047355A1 (en) * 1996-06-12 1997-12-18 Alza Corporation Reduction of skin sensitization in electrotransport drug delivery
US6306384B1 (en) * 1996-10-01 2001-10-23 E-L Management Corp. Skin battery cosmetic composition
US6800278B1 (en) 1996-10-28 2004-10-05 Ballard Medical Products, Inc. Inherently antimicrobial quaternary amine hydrogel wound dressings
US5800685A (en) * 1996-10-28 1998-09-01 Cardiotronics Systems, Inc. Electrically conductive adhesive hydrogels
FR2755842B1 (fr) * 1996-11-19 1999-04-23 Lhd Lab Hygiene Dietetique Procede de mesure de la resistance electrique cutanee d'un patient soumis a une administration transdermique de medicament
KR20000071103A (ko) * 1997-02-17 2000-11-25 요시히로 미와 이온토포레시스용 디바이스
US6775569B2 (en) * 1997-11-05 2004-08-10 Hisamitsu Pharmaceutical Co., Inc. Electroporation device for in vivo delivery of therapeutic agents
WO1999024015A1 (en) * 1997-11-12 1999-05-20 Alza Corporation Buffered drug formulations for transdermal electrotransport delivery
US6374136B1 (en) * 1997-12-22 2002-04-16 Alza Corporation Anhydrous drug reservoir for electrolytic transdermal delivery device
DK1051219T3 (da) * 1998-01-28 2005-01-10 Alza Corp Elektrokemisk reaktive katoder for en elektrotransportanordning
EP1115454B1 (de) * 1998-08-31 2006-10-25 Travanti Pharma Inc Gesteuerte medikamentdosierungsvorrichtung
DE69921489T2 (de) 1998-08-31 2005-10-27 Johnson & Johnson Consumer Companies, Inc. Elektrotransportvorrichtung mit klingen
US20050171021A1 (en) * 1998-11-12 2005-08-04 Cormier Michel J. Buffered drug formulations for transdermal
WO2000061220A1 (en) * 1999-04-13 2000-10-19 Hisamitsu Pharmaceutical Co., Inc. Iontophoresis device
US8852417B2 (en) 1999-04-13 2014-10-07 Applied Materials, Inc. Electrolytic process using anion permeable barrier
US8236159B2 (en) 1999-04-13 2012-08-07 Applied Materials Inc. Electrolytic process using cation permeable barrier
US20060157355A1 (en) * 2000-03-21 2006-07-20 Semitool, Inc. Electrolytic process using anion permeable barrier
AU4239300A (en) 1999-04-16 2000-11-02 Johnson & Johnson Consumer Companies, Inc. Electrotransport delivery system comprising internal sensors
US20030040665A1 (en) * 1999-05-28 2003-02-27 E-Monitors, Inc. Systems and methods of pH tissue monitoring
US6567679B1 (en) 1999-05-28 2003-05-20 E-Monitors, Inc. Method of using a pH tissue monitor
AU6076200A (en) 1999-07-08 2001-01-30 Johnson & Johnson Consumer Companies, Inc. Exothermic bandage
US6890553B1 (en) 1999-07-08 2005-05-10 Johnson & Johnson Consumer Companies, Inc. Exothermic topical delivery device
US7113821B1 (en) 1999-08-25 2006-09-26 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery
US7133717B2 (en) * 1999-08-25 2006-11-07 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery and diagnostic sampling
US6421561B1 (en) 1999-12-30 2002-07-16 Birch Point Medical, Inc. Rate adjustable drug delivery system
US20060260946A1 (en) * 2000-03-21 2006-11-23 Semitool, Inc. Copper electrolytic process using cation permeable barrier
US7404815B2 (en) * 2000-05-01 2008-07-29 Lifescan, Inc. Tissue ablation by shear force for sampling biological fluids and delivering active agents
US6653014B2 (en) 2001-05-30 2003-11-25 Birch Point Medical, Inc. Power sources for iontophoretic drug delivery systems
ITMI20012060A1 (it) * 2001-10-05 2003-04-05 Recordati Chem Pharm Nuovi eterocilcli n-acilati
AU2003221770A1 (en) * 2002-04-29 2003-11-17 Stephen T. Flock Controlled release transdermal drug delivery
AU2003282683A1 (en) 2002-10-04 2004-05-04 Photokinetix Inc. Photokinetic delivery of biologically active substances using pulsed incoherent light
US20070191815A1 (en) 2004-09-13 2007-08-16 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery
US20050197618A1 (en) * 2004-03-03 2005-09-08 Iomed, Inc. Improved buffer gel for iontophoresis electrodes
US8252321B2 (en) 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
US20060173514A1 (en) * 2005-02-02 2006-08-03 Advanced Photodynamic Technologies, Inc. Wound treatment device for photodynamic therapy and method of using same
US7856263B2 (en) * 2005-04-22 2010-12-21 Travanti Pharma Inc. Transdermal systems for the delivery of therapeutic agents including granisetron using iontophoresis
US8372040B2 (en) 2005-05-24 2013-02-12 Chrono Therapeutics, Inc. Portable drug delivery device including a detachable and replaceable administration or dosing element
US20070048249A1 (en) 2005-08-24 2007-03-01 Purdue Research Foundation Hydrophilized bactericidal polymers
EA023147B1 (ru) * 2006-04-13 2016-04-29 Тева Фармасьютикалс Интернешнл Гмбх Трансдермальный пластырь для лечения мигрени
US7904146B2 (en) * 2006-11-13 2011-03-08 Travanti Pharma Inc. Transdermal systems for the delivery of ionic agents directly to open wounds and surgically repaired incisions
US8197844B2 (en) 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
WO2009000262A1 (de) * 2007-06-25 2008-12-31 Acino Ag Elektrophoretisches transdermales applikationssystem
EP2178598A4 (de) * 2007-08-17 2012-08-15 Isis Biopolymer Llc Iontophoretisches arzneifreisetzungssystem
US8275441B2 (en) * 2007-11-02 2012-09-25 Tyco Healthcare Group Lp Electrodes possessing change indicator
CA2708497A1 (en) * 2007-12-10 2009-06-18 Isis Biopolymer Llc Iontophoretic drug delivery device and software application
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
US8155737B2 (en) * 2008-06-19 2012-04-10 Nupathe, Inc. Pharmacokinetics of iontophoretic sumatriptan administration
US8366600B2 (en) * 2008-06-19 2013-02-05 Nupathe Inc. Polyamine enhanced formulations for triptan compound iontophoresis
ES2526118T3 (es) 2008-12-30 2015-01-07 Nupathe Inc. Control electrónico de sistema de administración de fármacos
MX2011006925A (es) 2008-12-31 2011-07-28 Eyegate Pharma S A S Sistema y metodo de iontoforesis ocular con amortiguacion.
WO2010129928A1 (en) * 2009-05-08 2010-11-11 Isis Biopolymer Llc Iontophoretic device with improved counterelectrode
US20110092881A1 (en) * 2009-05-08 2011-04-21 Isis Biopolymer Inc. Iontophoretic device with contact sensor
CN105748401A (zh) 2009-08-10 2016-07-13 泰华制药国际有限公司 用离子电渗疗法治疗恶心和偏头痛的方法
US20110087153A1 (en) * 2009-10-13 2011-04-14 Angelov Angel S Transdermal Methods And Systems For The Delivery Of Rizatriptan
USD678534S1 (en) 2010-07-20 2013-03-19 Iontera, Inc. Iontophoretic device for application to the brow/forehead of a person
CA2817824A1 (en) 2010-11-23 2012-05-31 Nupathe, Inc. User-activated self-contained co-packaged iontophoretic drug delivery system
US10342968B2 (en) 2010-12-22 2019-07-09 Teikoku Seiyaku Co., Ltd. Electrode pad used for iontophoresis treatment
US20130017259A1 (en) 2011-07-06 2013-01-17 The Parkinson's Institute Compositions and Methods for Treatment of Symptoms in Parkinson's Disease Patients
FI125075B (fi) 2012-08-13 2015-05-29 Novagent Oy Vaikuttavan aineen iontoforeettinen annostelujärjestelmä
US10105487B2 (en) 2013-01-24 2018-10-23 Chrono Therapeutics Inc. Optimized bio-synchronous bioactive agent delivery system
FR3008320B1 (fr) * 2013-07-15 2018-04-20 Centre Hospitalier Univ Grenoble Dispositif de prevention ou de traitement d'une ulceration cutanee
CN103499519A (zh) * 2013-10-10 2014-01-08 河南科技大学 一种复合物理场经皮给药实验装置
WO2016123406A1 (en) 2015-01-28 2016-08-04 Chrono Therapeutics Inc. Drug delivery methods and systems
EP3267875A4 (de) 2015-03-12 2018-12-05 Chrono Therapeutics Inc. Eingabe- und unterstützungssystem für heftiges verlangen
WO2018129304A1 (en) 2017-01-06 2018-07-12 Chrono Therapeutics Inc. Transdermal drug delivery devices and methods
US20180340046A1 (en) 2017-05-27 2018-11-29 Poly Group LLC Dispersible antimicrobial complex and coatings therefrom
HUE068413T2 (hu) 2017-06-16 2024-12-28 Poly Group LLC Polimer, antimikrobiális felületaktív anyag
CA3101966A1 (en) 2018-05-29 2019-12-05 Morningside Venture Investments Limited Drug delivery methods and systems
US12397141B2 (en) 2018-11-16 2025-08-26 Morningside Venture Investments Limited Thermally regulated transdermal drug delivery system
DE102024003705A1 (de) 2024-11-12 2026-05-13 Alienworks S.A. Transdermales Pflaster zur gesteuerten Abgabe von Wirkstoffen unter Verwendung einer elektronischen Regelautomatik in Form einer Smartwatch

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA631424A (en) * 1961-11-21 H. Friedman Nathan Electrically conductive systems
US3989050A (en) * 1972-09-19 1976-11-02 Gilbert Buchalter Process for utilizing certain gel compositions for electrical stimulation
US3991755A (en) * 1973-07-27 1976-11-16 Medicon, Inc. Iontophoresis apparatus for applying local anesthetics
US4164226A (en) * 1976-08-25 1979-08-14 Robert Tapper Iontophoretic burn-protection electrode structure
US4211222A (en) * 1976-08-25 1980-07-08 Robert Tapper Iontophoretic burn-protection method
DE2727396C3 (de) * 1977-06-18 1983-12-08 Beiersdorf Ag, 2000 Hamburg Elektrisch leitendes, viskoelastisches Gel
US4163039A (en) * 1978-01-11 1979-07-31 Emrich Hinderk M Diagnostic means for the rapid detection of mucoviscidosis
US4301794A (en) * 1978-10-18 1981-11-24 Robert Tapper Method for iontophoretic treatment
US4340047A (en) * 1978-10-18 1982-07-20 Robert Tapper Iontophoretic treatment apparatus
US4416274A (en) * 1981-02-23 1983-11-22 Motion Control, Inc. Ion mobility limiting iontophoretic bioelectrode
JPS5810066A (ja) * 1981-07-10 1983-01-20 株式会社アドバンス イオントフオレ−ゼ用プラスタ−構造体
US4846182A (en) * 1982-01-11 1989-07-11 Medtronic, Inc. Method of preparing a fluid absorbent quantitative test device
US4444193A (en) * 1982-01-11 1984-04-24 Medtronic, Inc. Fluid absorbent quantitative test device
WO1986007269A1 (en) * 1985-06-10 1986-12-18 Drug Delivery Systems Inc. Programmable control and mounting system for transdermal drug applicator
US4708716A (en) * 1983-08-18 1987-11-24 Drug Delivery Systems Inc. Transdermal drug applicator
CA1262564A (en) * 1983-09-01 1989-10-31 Minoru Sasaki Iontophoresis device
US4744787A (en) * 1984-10-29 1988-05-17 Medtronic, Inc. Iontophoresis apparatus and methods of producing same
US4747819A (en) * 1984-10-29 1988-05-31 Medtronic, Inc. Iontophoretic drug delivery
US5135477A (en) * 1984-10-29 1992-08-04 Medtronic, Inc. Iontophoretic drug delivery
US4702732A (en) * 1984-12-24 1987-10-27 Trustees Of Boston University Electrodes, electrode assemblies, methods, and systems for tissue stimulation and transdermal delivery of pharmacologically active ligands
US4722726A (en) * 1986-02-12 1988-02-02 Key Pharmaceuticals, Inc. Method and apparatus for iontophoretic drug delivery
US4915685A (en) * 1986-03-19 1990-04-10 Petelenz Tomasz J Methods and apparatus for iontophoresis application of medicaments at a controlled ph through ion exchange
US4752285B1 (en) * 1986-03-19 1995-08-22 Univ Utah Res Found Methods and apparatus for iontophoresis application of medicaments
US4886489A (en) * 1986-03-19 1989-12-12 Jacobsen Stephen C Flow-through methods and apparatus for iontophoresis application of medicaments at a controlled pH
US4717378A (en) * 1986-03-31 1988-01-05 Medtronic, Inc. Methods for detecting dehydration of a biomedical hydrogel
US5042975A (en) * 1986-07-25 1991-08-27 Rutgers, The State University Of New Jersey Iontotherapeutic device and process and iontotherapeutic unit dose
US4752372A (en) * 1986-09-05 1988-06-21 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Moving wall, continuous flow electronphoresis apparatus
US4786277A (en) * 1986-11-21 1988-11-22 Trustees Of Boston University Electrodes, electrode assemblies, methods, and systems for tissue stimulation
KR900005223B1 (ko) * 1986-12-11 1990-07-21 가부시끼가이샤 호리바 세이사꾸쇼 이온농도등의 측정방법과 그 측정에 사용하는 계측기의 교정용시이트 및 교정방법
US4731049A (en) * 1987-01-30 1988-03-15 Ionics, Incorporated Cell for electrically controlled transdermal drug delivery
AU609769B2 (en) * 1987-02-10 1991-05-09 Drug Delivery Systems Inc. Electrolytic transdermal delivery of proteins
US4810418A (en) * 1987-03-23 1989-03-07 Minnesota Mining And Manufacturing Company Electrically conductive composition
US4842701A (en) * 1987-04-06 1989-06-27 Battelle Memorial Institute Combined electrophoretic-separation and electrospray method and system
US5362307A (en) * 1989-01-24 1994-11-08 The Regents Of The University Of California Method for the iontophoretic non-invasive-determination of the in vivo concentration level of an inorganic or organic substance
US5203327A (en) * 1988-09-08 1993-04-20 Sudor Partners Method and apparatus for determination of chemical species in body fluid
US4973303A (en) * 1989-09-05 1990-11-27 Empi, Inc. pH buffered electrode for medical iontophoresis
US5088978A (en) * 1990-01-26 1992-02-18 Gensia Pharmaceuticals, Inc. Apparatus and method for iontophoretic transfer
US5125894A (en) * 1990-03-30 1992-06-30 Alza Corporation Method and apparatus for controlled environment electrotransport
US5116759A (en) * 1990-06-27 1992-05-26 Fiberchem Inc. Reservoir chemical sensors
US5120545A (en) * 1990-08-03 1992-06-09 Alza Corporation Reduction or prevention of sensitization to drugs
EP0604504A4 (de) * 1991-08-26 1995-05-17 Univ Rutgers Iontotherapeutische vorrichtung und verfahren.

Also Published As

Publication number Publication date
AU681447B2 (en) 1997-08-28
NZ274317A (en) 1996-10-28
DE69410279D1 (de) 1998-06-18
US5533971A (en) 1996-07-09
EP0717645A1 (de) 1996-06-26
CA2166490C (en) 2004-08-10
DK0717645T3 (da) 1999-01-25
ES2116618T3 (es) 1998-07-16
JP3664726B2 (ja) 2005-06-29
AU7831394A (en) 1995-03-22
EP0717645B1 (de) 1998-05-13
CA2166490A1 (en) 1995-03-09
JPH09504191A (ja) 1997-04-28
DE69410279T2 (de) 1999-01-07
WO1995006497A1 (en) 1995-03-09

Similar Documents

Publication Publication Date Title
DE69410279D1 (de) Reduktion von hautirritationen und hautwiderstand während einer iontophoresebehandlung
SE9700182D0 (sv) Implantable heart stimulator
ATE514373T1 (de) Minimalinvasives system und verfahren zur überwachung von analytenkonzentrationen
WO1991008795A3 (en) Improved iontophoretic delivery method
AU591997B2 (en) Transdermal drug delivery device
ATE223176T1 (de) Herzschrittmacher mit elektrode und integriertem sauerstoff-fühler
EP0588238A3 (de) Elektrisch leitfähriges Polymergel und Verfahren zu seiner Herstellung und eine organisch brauchbare Elektrode und deren Verwendung.
DE69127342D1 (de) Behandlungssystem durch Iontophorese
EP0186071A3 (en) Transdermal system for timolol
CA2084734A1 (en) Iontophoresis system having features for reducing skin irritation
WO1997013505A3 (fr) UTILISATION D'UN LIGAND AGONISTE SPECIFIQUE RAR-η POUR AUGMENTER LE TAUX D'APOPTOSE
DE69221536D1 (de) Taktempfindlicher Herzschrittmacher
DE69426814D1 (de) Herzschrittmacher- und defibrillationselektrodenleitung, die die erfassung von signalen ermöglicht
IT1208521B (it) Elettrodo, apparecchiatura e defibrillazione per l'impianto in corpi umani o animali.
CA2001444A1 (en) Iontophoresis electrode
EP0337642A3 (de) Vorrichtung zur transdermalen Applikation von Arzneimitteln
BE905928A (fr) Dispositif therapeutique pour administrer un agent actif sur la peau.
ATE186654T1 (de) Vorrichtung zur befestigung von herzleitungen
DE69307819D1 (de) Herzschrittmacher-elektrode mit biologischer Stellschraube
AU1612588A (en) Pulsating transdermal drug delivery system
ATE222789T1 (de) Verfahren zur transdermalen verabreichung von medikamenten
EP0197358A3 (en) Topical use of 3-phenylacetylamino-2,6-piperidinedione for treatment of skin wrinkles and hyperpigmentation
DE68921937D1 (de) Steuerung bzw. Kontrolle des elektrokinetischen Potentials durch Behandlung mit Redoxmitteln.
EP1570879A3 (de) Gelmatrix für iontophoretische Elektroden
Strenta et al. Perceptions of Task Feedback

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee