ATE167232T1 - Protein mit knochenbildungs-eigenschaften und verfahren zu seiner herstellung - Google Patents

Protein mit knochenbildungs-eigenschaften und verfahren zu seiner herstellung

Info

Publication number
ATE167232T1
ATE167232T1 AT93104650T AT93104650T ATE167232T1 AT E167232 T1 ATE167232 T1 AT E167232T1 AT 93104650 T AT93104650 T AT 93104650T AT 93104650 T AT93104650 T AT 93104650T AT E167232 T1 ATE167232 T1 AT E167232T1
Authority
AT
Austria
Prior art keywords
production
bone
protein
forming properties
osf
Prior art date
Application number
AT93104650T
Other languages
English (en)
Inventor
Egon Dr Amann
Yoko Otawara-Hamamoto
Reiko Kikuno
Sunao Takeshita
Kenichi Tezuka
Original Assignee
Hoechst Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Japan filed Critical Hoechst Japan
Application granted granted Critical
Publication of ATE167232T1 publication Critical patent/ATE167232T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT93104650T 1992-03-27 1993-03-22 Protein mit knochenbildungs-eigenschaften und verfahren zu seiner herstellung ATE167232T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4071501A JPH05268982A (ja) 1992-03-27 1992-03-27 骨形成作用を有する新規な蛋白質およびその製造法

Publications (1)

Publication Number Publication Date
ATE167232T1 true ATE167232T1 (de) 1998-06-15

Family

ID=13462492

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93104650T ATE167232T1 (de) 1992-03-27 1993-03-22 Protein mit knochenbildungs-eigenschaften und verfahren zu seiner herstellung

Country Status (9)

Country Link
US (1) US5756664A (de)
EP (1) EP0562508B1 (de)
JP (1) JPH05268982A (de)
AT (1) ATE167232T1 (de)
CA (1) CA2092768A1 (de)
DE (1) DE69319012T2 (de)
DK (1) DK0562508T3 (de)
ES (1) ES2123582T3 (de)
GR (1) GR3027671T3 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995011923A1 (en) * 1993-10-29 1995-05-04 Dana-Farber Cancer Institute, Inc. A novel tumor marker and novel method of isolating same
SE520392C2 (sv) 1996-09-27 2003-07-01 Creative Peptides Sweden Ab C Specifika peptider för behandling av diabetes mellitus
JP2002502250A (ja) 1997-05-29 2002-01-22 ボード・オヴ・リージェンツ，ザ・ユニヴァーシティ・オヴ・テキサス・システム Ｏｓｆ２／ｃｂｆａ１組成物および使用の方法
EP1524524A1 (de) * 1998-12-18 2005-04-20 Scios Inc. Methode zur Detektion und Verwendung von differentiel exprimiertem OSF-2 in der Diagnose von Herzhypertrophie
WO2001057062A1 (en) * 2000-02-03 2001-08-09 Gene Logic, Inc. Modulation of osf-2 in inflammatory and renal diseases
DE60142693D1 (de) * 2000-09-08 2010-09-09 Daiichi Sankyo Co Ltd Arzneimittel für herzversagen
US7087727B2 (en) * 2001-08-13 2006-08-08 Dana-Farber Cancer Institute, Inc. Periostin-based diagnostic assays
CN100348277C (zh) * 2005-08-09 2007-11-14 中国人民解放军第三军医大学 成骨细胞特异性转录因子－2基因修饰的组织工程化骨的构建方法
JP5019464B2 (ja) 2005-12-28 2012-09-05 第一三共株式会社 抗ペリオスチン抗体およびそれを含有するペリオスチンが関与する疾患の予防または治療用医薬組成物
US8017119B2 (en) 2005-12-28 2011-09-13 Daiichi Sankyo Company, Ltd. Antibody against periostin, and a pharmaceutical composition comprising it for preventing or treating a disease in which periostin is involved
JP5238942B2 (ja) 2007-06-27 2013-07-17 国立大学法人大阪大学 ペリオスチンのＥｘｏｎ−１７部位によりコードされるペプチドに対する抗体を含む癌治療剤
JP6161233B2 (ja) * 2008-03-31 2017-07-12 ジェネンテック， インコーポレイテッド 喘息の治療及び診断のための組成物及び方法
US8420310B2 (en) * 2008-06-05 2013-04-16 Saga University Method for detection of idiopathic interstitial pneumonia
JP2012012344A (ja) * 2010-07-01 2012-01-19 Japan Health Science Foundation 創傷治癒剤
EP2652498B1 (de) 2010-12-16 2018-04-18 F.Hoffmann-La Roche Ag Diagnose und behandlungen im zusammenhang mit th2-hemmung
JP6183809B2 (ja) 2011-09-06 2017-08-23 株式会社シノテスト ペリオスチンの特定領域に結合する抗体及びこれを用いたペリオスチンの測定方法
JP6218088B2 (ja) 2013-03-08 2017-11-01 国立大学法人大阪大学 ペリオスチンのＥｘｏｎ−２１部位によりコードされるペプチドに対する抗体及び該抗体を含む炎症関連疾患の予防又は治療用医薬組成物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8078491A (en) * 1990-06-29 1992-01-23 Hoechst Japan Limited Novel protein capable of causing differential growth of cell and production thereof by genetic engineering technology
JPH09200324A (ja) * 1996-01-12 1997-07-31 Ricoh Co Ltd ファクシミリ装置

Also Published As

Publication number Publication date
CA2092768A1 (en) 1993-09-28
JPH05268982A (ja) 1993-10-19
EP0562508B1 (de) 1998-06-10
DK0562508T3 (da) 1999-03-29
EP0562508A2 (de) 1993-09-29
DE69319012D1 (de) 1998-07-16
US5756664A (en) 1998-05-26
GR3027671T3 (en) 1998-11-30
DE69319012T2 (de) 1998-12-17
EP0562508A3 (en) 1994-06-22
ES2123582T3 (es) 1999-01-16

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