ATE167471T1 - Tryptamin analoge mit 5-ht1d selektivität - Google Patents

Tryptamin analoge mit 5-ht1d selektivität

Info

Publication number
ATE167471T1
ATE167471T1 AT94925317T AT94925317T ATE167471T1 AT E167471 T1 ATE167471 T1 AT E167471T1 AT 94925317 T AT94925317 T AT 94925317T AT 94925317 T AT94925317 T AT 94925317T AT E167471 T1 ATE167471 T1 AT E167471T1
Authority
AT
Austria
Prior art keywords
ht1d
4alkyl
chain
selectivity
receptor
Prior art date
Application number
AT94925317T
Other languages
English (en)
Inventor
Richard A Glennon
Original Assignee
Allelix Biopharma
Univ Virginia Commonwealth
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allelix Biopharma, Univ Virginia Commonwealth filed Critical Allelix Biopharma
Application granted granted Critical
Publication of ATE167471T1 publication Critical patent/ATE167471T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
AT94925317T 1993-09-01 1994-08-31 Tryptamin analoge mit 5-ht1d selektivität ATE167471T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11500393A 1993-09-01 1993-09-01

Publications (1)

Publication Number Publication Date
ATE167471T1 true ATE167471T1 (de) 1998-07-15

Family

ID=22358755

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94925317T ATE167471T1 (de) 1993-09-01 1994-08-31 Tryptamin analoge mit 5-ht1d selektivität

Country Status (7)

Country Link
EP (1) EP0666847B1 (de)
JP (1) JPH08506357A (de)
AT (1) ATE167471T1 (de)
AU (1) AU685837B2 (de)
CA (1) CA2147991A1 (de)
DE (1) DE69411143T2 (de)
WO (1) WO1995006638A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2724933A1 (fr) * 1994-09-22 1996-03-29 Pf Medicament Nouveaux ethers aromatiques derives d'indoles utiles comme medicaments
US5654431A (en) * 1996-05-30 1997-08-05 Meng; Qingchang 5-alkoxy tryptamine derivatives
US5998462A (en) * 1996-12-16 1999-12-07 Allelix Biopharmaceuticals Inc. 5-alkyl indole compounds
US20030235557A1 (en) 1998-09-30 2003-12-25 Corixa Corporation Compositions and methods for WT1 specific immunotherapy
SI1859798T1 (sl) 2001-03-29 2016-07-29 Eli Lilly And Company N-(2-ariletil) benzil amini kot antagonisti 5-ht6 receptorja
KR100411599B1 (ko) * 2001-10-23 2003-12-18 동방에프티엘 주식회사 5-치환된 인돌 유도체의 제조방법
JO3459B1 (ar) 2012-09-09 2020-07-05 H Lundbeck As تركيبات صيدلانية لعلاج مرض الزهايمر
EP4146198A4 (de) 2020-05-08 2024-05-15 Psilera Inc. Neue stoffzusammensetzungen und pharmazeutische zusammensetzungen
JP7702654B2 (ja) * 2020-06-30 2025-07-04 リユニオン・ニューロサイエンス、インコーポレイテッド トリプタミンプロドラッグ
CA3218110A1 (en) 2021-05-25 2022-12-01 Majed Fawaz New n,n-dimethyltryptamine salts and crystalline salt forms
US20230041584A1 (en) * 2021-06-09 2023-02-09 ATAI Life Sciences AG Novel prodrugs and conjugates of dimethyltryptamine
EP4457214A4 (de) 2021-12-30 2025-12-03 Atai Therapeutics Inc Dimethyltryptamin-analoga als stickoxid-abgabemittel

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3317560A (en) * 1963-01-03 1967-05-02 Philips Corp Indol-3-yl alkylguanidine derivatives
GB8600398D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
GB9103770D0 (en) * 1991-02-22 1991-04-10 Glaxo Group Ltd Chemical compounds
CA2110574A1 (en) * 1991-06-21 1993-01-07 Lawrence I. Kruse Tryptamine analogues, their synthesis and their use as 5-ht1-like or 5-ht2 receptor agonists

Also Published As

Publication number Publication date
DE69411143D1 (de) 1998-07-23
EP0666847B1 (de) 1998-06-17
AU7528594A (en) 1995-03-22
WO1995006638A1 (en) 1995-03-09
CA2147991A1 (en) 1995-03-09
EP0666847A1 (de) 1995-08-16
JPH08506357A (ja) 1996-07-09
AU685837B2 (en) 1998-01-29
DE69411143T2 (de) 1998-10-22

Similar Documents

Publication Publication Date Title
DE69411143D1 (de) Tryptamin analoge mit 5-ht1d selektivität
ES2133416T3 (es) Ligandos de subtipos de receptores de dopamina.
ATE180479T1 (de) Sulfonat- und carbamatderivate von 3-aroyl- benzo(beta)thiophenen
DE3889536D1 (de) Behandlung von krebs mit somatostatin und mit analogen davon.
DE3371785D1 (en) Novel crystal modifications, processes for their production, and pharmaceutical preparations containing them
AU587054B2 (en) Novel pharmaceutical compositions intended to the treatment of neuropathies and insuring the nervous regeneration
ES2058272T3 (es) Fluoxetina util para el tratamiento de la diabetes.
DE3686022D1 (de) Monosaccharide enthaltende zusammensetzung zum heilen von wunden.
ES8502998A1 (es) Procedimiento para la preparacion de nuevas b-carbolinas substituidas.
CA2188798A1 (en) Tryptamine Derivatives as 5-HT-1D Receptor Ligands
ZA886097B (en) Pharmaceutical composition for the treatment of psoriasis
DK0399185T3 (da) Fremgangsmåde til formindskelse af svovlindholdet i organiske sulfider
ES2099865T3 (es) Ciclopentanoperhidrofenantreno-17beta-(3-furil)-3-derivados y composiciones farmaceuticas que comprenden los mismos para el tratamiento de trastornos cardiovasculares.
ATE114468T1 (de) Ethyl-(+)-apovincaminat zur behandlung der demyelinisierung klinischer erscheinungen autoimmunen ursprungs.
PT86619A (pt) Process for preparing alkylmelatonins
ES2077561T3 (es) Proceso para la modificacion de un tamiz molecular.
ES2081834T3 (es) Pirrolidin-2-onas 4-metil y 4-etil sustituidas.
KR950700684A (ko) 시클릭 항-종양 촉진제 화합물, 그의 조성물, 제조 방법 및 용도(Cyclic Anti-Tumor Promoter Compounds, Compositions and Methods for Production and Use)
SE8404334D0 (sv) 16-fluoro-16,17-didehydro-prostanoids and process for their preparation
ES462643A1 (es) Procedimiento para la preparacion de compuestos antraquini- nicos.
NO882010L (no) Svovelopploesende blanding.
CA1268468C (en) PROSTAGLANDIN ANALOGS WITH SUBSTITUTE THIABICYCLOHEPTAN GROUP
ATE30907T1 (de) Verfahren zur stabilisierung von chlorkohlenwasserstoffen, verfahrensgemaess stabilisierte chlorkohlenwasserstoff und ihre verwendung.
EP0266665A3 (en) Treatment of inflammatory articular diseases
NO950114L (no) Amylin-antagonister og agonister

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee